Effects of high-impact training and detraining on femoral neck structure in premenopausal women: A hip structural analysis of an 18-month randomized controlled exercise intervention with 3.5-year follow-up

Physiotherapy Canada

Volumn 64, Issue 1, 2012, Pages 98-105

  Heinonen, Ari ^a   Mäntynen, Jyri ^b   Kannus, Pekka ^c,d   Uusi Rasi, Kirsti ^c   Nikander, Riku ^c   Kontulainen, Saija ^e   Sievänen, Harri ^c  

^a UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^b KuntoFysio   (Finland)

^c UKK INSTITUTE FOR HEALTH PROMOTION RESEARCH   (Finland)

^d TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^e UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Bone and bones; Bone mineral density; Exercise; Osteoporosis; Women

Indexed keywords

EID: 84856859288     PISSN: 03000508     EISSN: None     Source Type: Journal    
DOI: 10.3138/ptc.2010-37     Document Type: Article

References (53)

1. Kannus P, Sievänen H, Palvanen M, et al. Prevention of falls and consequent injuries in elderly people. Lancet. 2005;366(9500):1885-93. doi:10.1016/S0140-6736(05)67604-0. Medline:16310556
2. Järvinen TL, Sievänen H, Khan KM, et al. Shifting the focus in fracture prevention from osteoporosis to falls. BMJ. 2008;336(7636):124-6. doi:10.1136/bmj.39428.470752.AD. Medline:18202065
3. Karinkanta S, Piirtola M, Sievänen H, et al. Physical therapy approaches to reduce fall and fracture risk among older adults. Nat Rev Endocrinol. 2010;6(7):396-407. doi:10.1038/nrendo.2010.70. Medline:20517287
4. Nikander R, Sievänen H, Heinonen A, et al. Targeted exercise against osteoporosis: A systematic review and meta-analysis for optimising bone strength throughout life. BMC Med. 2010;8(1):47. doi:10.1186/1741-7015-8-47. Medline:20663158
5. Hamilton CJ, Thomas SG, Jamal SA. Associations between leisure physical activity participation and cortical bone mass and geometry at the radius and tibia in a Canadian cohort of postmenopausal women. Bone. 2010;46(3):774-9. doi:10.1016/j.bone.2009.10.041. Medline:19897064
6. Wolff I, van Croonenborg JJ, Kemper HC, et al. The effect of exercise training programs on bone mass: a meta-analysis of published controlled trials in pre-and postmenopausal women. Osteoporos Int. 1999;9(1):1-12. doi:10.1007/s001980050109. Medline:10367023
7. Wallace BA, Cumming RG. Systematic review of randomized trials of the effect of exercise on bone mass in pre-and postmenopausal women. Calcif Tissue Int. 2000;67(1):10-8. doi:10.1007/s00223001089. Medline:10908406
8. Kelley GA, Kelley KS. Efficacy of resistance exercise on lumbar spine and femoral neck bone mineral density in premenopausal women: a meta-analysis of individual patient data. J Womens Health (Larchmt). 2004;13(3):293-300. doi:10.1089/154099904323016455. Medline:15130258
9. Kelley GA, Kelley KS, Tran ZV. Exercise and lumbar spine bone mineral density in postmenopausal women: a meta-analysis of individual patient data. J Gerontol A Biol Sci Med Sci. 2002;57(9):M599-604. Medline:12196498
10. Kelley GA, Kelley KS, Tran ZV. Exercise and bone mineral density in men: a meta-analysis. J Appl Physiol. 2000;88(5):1730-6. Medline:10797136
11. Kelley GA. Exercise and regional bone mineral density in postmenopausal women: a meta-analytic review of randomized trials. Am J Phys Med Rehabil. 1998;77(1):76-87. doi:10.1097/00002060-199801000-00015. Medline:9482383
12. Snow-Harter C, Bouxsein ML, Lewis BT, et al. Effects of resistance and endurance exercise on bone mineral status of young women: a randomized exercise intervention trial. J Bone Miner Res. 1992;7(7):761-9. doi:10.1002/jbmr.5650070706. Medline:1642145
13. Bassey EJ, Ramsdale SJ. Increase in femoral bone density in young women following high-impact exercise. Osteoporos Int. 1994;4(2):72-5. doi:10.1007/BF01623226. Medline:8003843
14. Friedlander AL, Genant HK, Sadowsky S, et al. A two-year program of aerobics and weight training enhances bone mineral density of young women. J Bone Miner Res. 1995;10(4):574-85. doi:10.1002/jbmr.5650100410. Medline:7610928
15. Heinonen A, Kannus P, Sievänen H, et al. Randomised controlled trial of effect of high-impact exercise on selected risk factors for osteoporotic fractures. Lancet. 1996;348(9038):1343-7. doi:10.1016/S0140-6736(96)04214-6. Medline:8918277
16. Heinonen A, Oja P, Sievänen H, et al. Effect of two training regimens on bone mineral density in healthy perimenopausal women: a randomized controlled trial. J Bone Miner Res. 1998;13(3):483-90. doi:10.1359/jbmr.1998.13.3.483. Medline:9525349
17. Vainionpää A, Korpelainen R, Leppäluoto J, et al. Effects of highimpact exercise on bone mineral density: a randomized controlled trial in premenopausal women. Osteoporos Int. 2005;16(2):191-7. doi:10.1007/s00198-004-1659-5. Medline:15221206
18. Vainionpää A, Korpelainen R, Leppäluoto J, et al. Effects of highimpact exercise on bone mineral density: a randomized controlled trial in premenopausal women. Osteoporos Int. 2005;16(2):191-7. doi:10.1007/s00198-004-1659-5. Medline:15221206
19. Karinkanta S, Heinonen A, Sievänen H, et al. A multi-component exercise regimen to prevent functional decline and bone fragility in home-dwelling elderly women: randomized, controlled trial. Osteoporos Int. 2007;18(4):453-62. doi:10.1007/s00198-006-0256-1. Medline:17103296
20. Bailey CA, Brooke-Wavell K. Optimum frequency of exercise for bone health: randomised controlled trial of a high-impact unilateral intervention. Bone. 2010;46(4):1043-9. doi:10.1016/j.bone.2009.12.001. Medline:20004758
21. Järvinen TL, Kannus P, Sievänen H. Have the DXA-based exercise studies seriously underestimated the effects of mechanical loading on bone [letter; comment]? J Bone Miner Res. 1999;14(9):1634-5. doi:10.1359/jbmr.1999.14.9.1634. Medline:10469294
22. Sievänen H, Kannus P. Physical activity reduces the risk of fragility fracture. PLoS Med. 2007;4(6):e222. doi:10.1371/journal.pmed.0040222. Medline:17579512
23. Järvinen TL, Sievänen H, Jokihaara J, et al. Revival of bone strength: the bottom line. J Bone Miner Res. 2005;20(5):717-20. doi:10.1359/JBMR.050211. Medline:15824843
24. Sievänen H, Kannus P, Järvinen TL. Bone quality: an empty term. PLoS Med. 2007;4(3):e27. doi:10.1371/journal.pmed.0040027. Medline:17341126
25. Kontulainen S, Heinonen A, Kannus P, et al. Former exercisers of an 18-month intervention display residual aBMD benefits compared with control women 3.5 years post-intervention: a follow-up of a randomized controlled high-impact trial. Osteoporos Int. 2004;15(3):248-51. doi:10.1007/s00198-003-1559-0. Medline:14673517
26. Beck TJ, Ruff CB, Warden KE, et al. Predicting femoral neck strength from bone mineral data. A structural approach. Invest Radiol. 1990;25(1):6-18. doi:10.1097/00004424-199001000-00004. Medline:2298552
27. Beck TJ, Looker AC, Ruff CB, et al. Structural trends in the aging femoral neck and proximal shaft: analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res. 2000;15(12):2297-304. doi:10.1359/jbmr.2000.15.12.2297. Medline:11127194
28. Sievänen H, Kannus P, Nieminen V, et al. Estimation of various mechanical characteristics of human bones using dual energy X-ray absorptiometry: methodology and precision. Bone. 1996;18(1 Suppl): S17-27. doi:10.1016/8756-3282(95)00376-2. Medline:8717544
29. Nikander R, Sievänen H, Heinonen A, et al. Femoral neck structure in adult female athletes subjected to different loading modalities. J Bone Miner Res. 2005;20(3):520-8. doi:10.1359/JBMR.041119. Medline:15746998
30. Sillanpää J, Sievänen H, Heinonen A, et al. Reproducibility of a novel measurement and analytic method for jump testing. In: Häkkinen K, Keskinen KL, Komi PV, Mero A, editors. XVth Congress of the International Society of Biomechanics: book of abstracts. Jyväskylä, Finland: the Society; 1995. pp. 850-851.
31. Oja P, Laukkanen R, Pasanen M, et al. A 2-km walking test for assessing the cardiorespiratory fitness of healthy adults. Int J Sports Med. 1991;12(4):356-62. doi:10.1055/s-2007-1024694. Medline:1917218
32. Laukkanen RM, Kukkonen-Harjula TK, Oja P, et al. Prediction of change in maximal aerobic power by the 2-km walk test after walking training in middle-aged adults. Int J Sports Med. 2000;21(2):113-6. doi:10.1055/s-2000-8872. Medline:10727071
33. Sievänen H. Measuring small changes versus measurement error. J Bone Miner Res. 2008;23:576-7; author reply 578-9.
34. Heinonen A, Sievänen H, Kyröläinen H, et al. Mineral mass, size, and estimated mechanical strength of triple jumpers' lower limb. Bone. 2001;29(3):279-85. doi:10.1016/S8756-3282(01)00574-9. Medline:11557373
35. Haapasalo H, Kontulainen S, Sievänen H, et al. Exercise-induced bone gain is due to enlargement in bone size without a change in volumetric bone density: a peripheral quantitative computed tomography study of the upper arms of male tennis players. Bone. 2000;27(3):351-7. doi:10.1016/S8756-3282(00)00331-8. Medline:10962345
36. Kontulainen S, Sievänen H, Kannus P, et al. Effect of long-term impact-loading on mass, size, and estimated strength of humerus and radius of female racquet-sports players: a peripheral quantitative computed tomography study between young and old starters and controls. J Bone Miner Res. 2003;18(2):352-9. doi:10.1359/jbmr.2003.18.2.352. Medline:12568413
37. Heinonen A, Sievänen H, Kannus P, et al. Site-specific skeletal response to long-term weight training seems to be attributable to principal loading modality: a pQCT study of female weightlifters. Calcif Tissue Int. 2002;70(6):469-74. doi:10.1007/s00223-001-1019-9. Medline:12016461
38. Sievänen H. A physical model for dual-energy X-ray absorptiometryderived bone mineral density. Invest Radiol. 2000;35(5):325-30. doi:10.1097/00004424-200005000-00007. Medline:10803674
39. Petit MA, McKay HA, MacKelvie KJ, et al. A randomized schoolbased jumping intervention confers site and maturity-specific benefits on bone structural properties in girls: a hip structural analysis study. J Bone Miner Res. 2002;17(3):363-72. doi:10.1359/jbmr.2002.17.3.363. Medline:11874228
40. Sievänen H. Immobilization and bone structure in humans. Arch Biochem Biophys. 2010;503(1):146-52. doi:10.1016/j.abb.2010.07.008. Medline:20637174
41. Vuori I, Heinonen A, Sievänen H, et al. Effects of unilateral strength training and detraining on bone mineral density and content in young women: a study of mechanical loading and deloading on human bones. Calcif Tissue Int. 1994;55(1):59-67. doi:10.1007/BF00310170. Medline:7922791
42. Kontulainen S, Kannus P, Haapasalo H, et al. Changes in bone mineral content with decreased training in competitive young adult tennis players and controls: a prospective 4-yr follow-up. Med Sci Sports Exerc. 1999;31(5):646-52. doi:10.1097/00005768-199905000-00004. Medline:10331882
43. Nordström A, Karlsson C, Nyquist F, et al. Bone loss and fracture risk after reduced physical activity. J Bone Miner Res. 2005;20(2):202-7. doi:10.1359/JBMR.041012. Medline:15647813
44. Kontulainen S, Kannus P, Haapasalo H, et al. Good maintenance of exercise-induced bone gain with decreased training of female tennis and squash players: a prospective 5-year follow-up study of young and old starters and controls. J Bone Miner Res. 2001;16(2):195-201. doi:10.1359/jbmr.2001.16.2.195. Medline:11204418
45. Karlsson MK, Johnell O, Obrant KJ. Is bone mineral density advantage maintained long-term in previous weight lifters? Calcif Tissue Int. 1995;57(5):325-8. doi:10.1007/BF00302066. Medline:8564793
46. Bass S, Pearce G, Bradney M, et al. Exercise before puberty may confer residual benefits in bone density in adulthood: studies in active prepubertal and retired female gymnasts. J Bone Miner Res. 1998;13(3):500-7. doi:10.1359/jbmr.1998.13.3.500. Medline:9525351
47. Kudlac J, Nichols DL, Sanborn CF, et al. Impact of detraining on bone loss in former collegiate female gymnasts. Calcif Tissue Int. 2004;75(6):482-7. doi:10.1007/s00223-004-0228-4. Medline:15365660
48. Zanker CL, Osborne C, Cooke CB, et al. Bone density, body composition and menstrual history of sedentary female former gymnasts, aged 20-32 years. Osteoporos Int. 2004;15(2):145-54. doi:10.1007/ s00198-003-1524-y. Medline:14647879
49. Heinonen A, Oja P, Kannus P, et al. Bone mineral density in female athletes representing sports with different loading characteristics of the skeleton. Bone. 1995;17(3):197-203. doi:10.1016/8756-3282(95)00151-3. Medline:8541131
50. Nikander R, Kannus P, Dastidar P, et al. Targeted exercises against hip fragility. Osteoporos Int. 2009;20(8):1321-8. doi:10.1007/s00198-008-0785-x. Medline:19002370
51. Lanyon LE. Using functional loading to influence bone mass and architecture: objectives, mechanisms, and relationship with estrogen of the mechanically adaptive process in bone. Bone. 1996;18(1 Suppl): S37-43. doi:10.1016/8756-3282(95)00378-9. Medline:8717546
52. Chodzko-Zajko WJ, Proctor DN, Fiatarone Singh MA, et al; American College of Sports Medicine. American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc. 2009;41(7):1510-30. doi:10.1249/MSS.0b013e3181a0c95c. Medline:19516148
53. Beck TJ. Measuring the structural strength of bones with dual-energy X-ray absorptiometry: principles, technical limitations, and future possibilities. Osteoporos Int. 2003;14(Suppl 5):81-8. doi:10.1007/ s00198-003-1478-0. Medline:14504711