Predictive ability of serum high-molecular-weight adiponectin in combination with serum insulin and serum C-reactive protein for the presence of metabolic syndrome

Annals of Human Biology

Volumn 39, Issue 2, 2012, Pages 108-112

  Kawada, Tomoyuki ^a   Hasegawa, Miyuki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

C reactive protein; High molecular weight adiponectin; Insulin; Liver enzymes; Metabolic syndrome

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; GAMMA GLUTAMYLTRANSFERASE; INSULIN; URIC ACID;

ENZYME ACTIVITY; HEALTH RISK; HORMONE; OBESITY; PROTEIN; REGRESSION ANALYSIS; SERUM;

ADULT; ARTICLE; BLOOD; HUMAN; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PREDICTIVE VALUE;

ADIPONECTIN; ADULT; ALANINE TRANSAMINASE; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; URIC ACID;

EID: 84856832831     PISSN: 03014460     EISSN: 14645033     Source Type: Journal    
DOI: 10.3109/03014460.2011.652170     Document Type: Article

References (26)

1. Alberti KGM, Zimmet P, Shaw J. 2005. The metabolic syndrome: a new worldwide definition. Lancet 366:1059-1062. (Pubitemid 41338752)
2. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. 1999. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257:79-83. (Pubitemid 29299050)
3. Berg AH, Combs TP, Scherer PE. 2002. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13:84-89. (Pubitemid 36740452)
4. Berkman LF, Breslow L. 1983. Health and ways of living. New York: Oxford University Press.
5. Bray GA, Bellanger T. 2006. Epidemiology, trends, and morbidities of obesity and the metabolic syndrome. Endocrine 29:109-117. (Pubitemid 43780352)
6. Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, Tanen M, Berg AH, O'Rahilly S, Savage DB, Chatterjee K, Weiss S, Larson PJ, Gottesdiener KM, Gertz BJ, Charron MJ, Scherer PE, Moller DE. 2002. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 143:998-1007. (Pubitemid 34164048)
7. Dullaart RP, de Vries R, van Tol A, Sluiter WJ. 2007. Lower plasma adiponectin is a marker of increased intima-media thickness associated with type 2 diabetes mellitus and with male gender. Eur J Endocrinol 156:387-394. (Pubitemid 46554507)
8. Fujimatsu D, Kotooka N, Inoue T, Nishiyama M, Node K. 2009. Association between high molecular weight adiponectin levels and metabolic parameters. J Atheroscler Thromb 16:553-559.
9. Gable DR, Hurel SJ, Humphries SE. 2006. Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic syndrome and cardiovascular disease. Atherosclerosis 188:231-244. (Pubitemid 44301148)
10. Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T. 2006. Measurement of the highmolecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome. Diabetes Care 29:1357-1362. (Pubitemid 44125935)
11. Heidemann C, Sun Q, van Dam RM, Meigs JB, Zhang C, Tworoger SS, Mantzoros CS, Hu FB. 2008. Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. Ann Intern Med 149:307-316.
12. Herder C, Hauner H, Haastert B, Rohrig K, KoenigW, Kolb H, Muller- Scholze S, Thorand B, Holle R, Rathmann W. 2006. Hypoadiponectinemia and proinflammatory state: two sides of the same coin?: results from the Cooperative Health Research in the Region of Augsburg Survey 4 (KORA S4). Diabetes Care 29:1626-1631. (Pubitemid 44127591)
13. Hirose H, Yamamoto Y, Seino-Yoshihara Y, Kawabe H, Saito I. 2010. Serum high-molecular-weight adiponectin as a marker for the evaluation and care of subjects with metabolic syndrome and related disorders. J Atheroscler Thromb 17:1201-1211.
14. Hung J, McQuillan BM, Thompson PL, Beilby JP. 2008. Circulating adiponectin levels associate with inflammatory markers, insulin resistance and metabolic syndrome independent of obesity. Int J Obes (Lond) 32:772-779. (Pubitemid 351670618)
15. International Diabetes Federation (IDF). 2006. The IDF Consensus Worldwide Definition of the Metabolic Syndrome. Available online at: http://www.idf.org/webdata/docs/IDF-Meta-def-final. pdf, accessed February 1, 2012.
16. Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. 2006. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116: 1784-1792. (Pubitemid 44033298)
17. Kuo SM, Halpern MM. 2011. Lack of association between body mass index and plasma adiponectin levels in healthy adults. Int J Obes (Lond) 35:1487-1494.
18. Li S, Shin HJ, Ding EL, van Dam RM. 2009. Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis. JAMA 302:179-188.
19. Libby P, Okamoto Y, Rocha VZ, Folco E. 2010. Inflammation in atherosclerosis: transition from theory to practice. Circ J 74: 213-220.
20. Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Takefuji S, Sugiura K, Kondo T, Murohara T, Toyoshima H. 2006. Comparison of circulating adiponectin and proinflammatory markers regarding their association with metabolic syndrome in Japanese men. Arterioscler Thromb Vasc Biol 26:871-876. (Pubitemid 43732165)
21. National Cholesterol Education Program (NCEP). 2002. Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation 106:3143-3421.
22. Saisho Y, Hirose H, Seino Y, Saito I, Itoh H. 2010. Usefulness of C-reactive protein to high-molecular-weight adiponectin ratio to predict insulin resistance and metabolic syndrome in Japanese men. J Atheroscler Thromb 17:944-952.
23. Seino Y, Hirose H, Saito I, Itoh H. 2007. High molecular weight multimer form of adiponectin as a useful marker to evaluate insulin resistance and metabolic syndrome in Japanese men. Metabolism 56:1493-1499. (Pubitemid 47562499)
24. Seino Y, Hirose H, Saito I, Itoh H. 2009. High-molecular-weight adiponectin is a predictor of progression to metabolic syndrome: a population-based 6-year follow-up study in Japanese men. Metabolism 58:355-360.
25. Tsao TS, Lodish HF, Fruebis J. 2002. ACRP30, a new hormone controlling fat and glucose metabolism. Eur J Pharmacol 440: 213-221. (Pubitemid 34458025)
26. Wannamethee SG, Tchernova J, Whincup P, Lowe GD, Rumley A, Brown K, Cherry L, Sattar N. 2007. Associations of adiponectin with metabolic and vascular risk parameters in the British regional heart study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters. Int J Obes (Lond) 31:1089-1098. (Pubitemid 46987759)