Interferon-inducible genes, TNF-related apoptosis-inducing ligand (TRAIL) and interferon inducible protein 27 (IFI27) are negatively regulated in leiomyomas: Implications for a role of the interferon pathway in leiomyoma development

Gynecological Endocrinology

Volumn 28, Issue 3, 2012, Pages 216-219

  Mihalich, Alessandra ^a   Viganò, Paola ^b   Gentilini, Davide ^a   Borghi, Maria Orietta ^c   Vignali, Michele ^c   Busacca, Mauro ^c   Di Blasio, Annamaria ^a  

^a ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

IFI27; IFN ; Leiomyoma; Miometrium; TRAIL

Indexed keywords

CHEMOKINE; INTERFERON INDUCIBLE PROTEIN 27; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRIDIZATION; LEIOMYOMA; MYOMETRIUM; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; TUMOR GROWTH;

CELLS, CULTURED; DOWN-REGULATION; FEMALE; HUMANS; INTERFERON-ALPHA; LEIOMYOMA; MEMBRANE PROTEINS; MICROARRAY ANALYSIS; MYOMETRIUM; PREMENOPAUSE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; UTERINE NEOPLASMS;

EID: 84856832198     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2011.588746     Document Type: Article

References (28)

1. Ferenczy A, Richart RM, Okagaki T. A comparative ultrastuctural study of leiomyosarcoma, cellular leiomyoma, and leiomyoma of the uterus. Cancer 1971;28:1004-1018.
2. Packenham JP, du Manoir S, Schrock E, Risinger JI, Dixon D, Denz DN. Analysis of genetic alteration in uterine leiomyomas and leiomyosarcomas by comparative genomic hybridization. Mol Carcinog 1997;19:273-274.
3. Brandon DD, Bethea CL, Strawn EY, Novy MJ, Burry KA, Harrington MS, Erickson TE, et al. Progesterone receptor messenger ribonucleic acid and protein are overexpressed in human uterine leiomyomas. Am J Obstet Gynecol 1993;169:78-85. (Pubitemid 23223932)
4. Brandon DD, Erickson TE, Keenan EJ, Strawn EY, Novy MJ, Burry KA, Warner C, Clinton GM. Estrogen receptor gene expression in human uterine leiomyomata. J Clin Endocrinol Metab 1995;80:1876-1881.
5. Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. How cells respond to interferons. Annu Rev Biochem 1998;67:227-264. (Pubitemid 28411130)
6. Tyrell L, Erickson S, Zhivotovsky B, Pokrovskaja K, Sangfelt O, Castro J, Einhorn S, Grandér D. Mechanisms of Interferon-alpha induced apoptosis in malignant cells. Oncogene 2002;21:1251-1262. (Pubitemid 34185242)
7. Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-1421. (Pubitemid 24217131)
8. Der SD, Zhou A, Williams BR, Silverman RH. Identifcation of genes diferentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc Natl Acad Sci USA 1998;95:15623-15628. (Pubitemid 29018750)
9. Minakuchi K, Kawamura N, Tsujimura A, Ogita S. Remarkable and persistent shrinkage of uterine leiomyoma associated with interferon alfa treatment for hepatitis. Lancet 1999;353:2127-2128. (Pubitemid 29278487)
10. Wiley SR, Schooley K, Smolak PJ, Din WS, Huang C P, Nicholl JK, Sutherland GR, et al. Identifcation and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995;3:673-682. (Pubitemid 26091143)
11. Rasmussen UB, Wolf C, Mattei MG, Chenard MP, Bellocq JP, Chambon P, Rio MC, Basset P. Identifcation of a new interferon-alpha-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma. Cancer Res 1993;53:4096-4101. (Pubitemid 23267717)
12. Mangioni S, Viganò P, Lattuada D, Abbiati A, Vignali M, Di Blasio AM. Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor. J Clin Endocrinol Metab 2005;90:5349-5355. (Pubitemid 41262300)
13. Taylor M W, Grosse WM, Schaley JE, Sanda C, Wu X, Chien SC, Smith F, et al. Global efect of PEG-IFN-alpha and ribavirin on gene expression in PBMC in vitro. J Interferon Cytokine Res 2004;24:107-118. (Pubitemid 38253638)
14. Martensen PM, Justesen J. Small ISGs coming forward. J Interferon Cytokine Res 2004;24:1-19. (Pubitemid 38152967)
15. Gjermandsen IM, Justesen J, Martensen PM. The interferon-induced gene ISG12 is regulated by various cytokines as the gene 6-16 in human cell lines. Cytokine 2000;12:233-238. (Pubitemid 30449880)
16. Kayagaki N, Yamaguchi N, Nakayama M, Eto H, Okumura K, Yagita H. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor efects of type I IFNs. J Exp Med 1999;189:1451-1460. (Pubitemid 29227531)
17. Hofman PJ, Milliken DB, Gregg LC, Davis RR, Gregg JP. Molecular characterization of uterine fbroids and its implication for underlying mechanisms of pathogenesis. Fertil Steril 2004;82:639-649. (Pubitemid 39243186)
18. Tsibris JC, Segars J, Coppola D, Mane S, Wilbanks GD, O'Brien WF, Spellacy WN. Insights from gene arrays on the development and growth regulation of uterine leiomyomata. Fertil Steril 2002;78:114-121. (Pubitemid 34722680)
19. Woong Shick A, Ko-Woon K, Su Mi B et al. Targeted cellular process profling approach for uterine leiomyoma using cDNA microarray, proteomics and gene ontology analysis. Int J Exp Path 2003;84:267-279.
20. Arslan AA, Gold LI, Mittal K, Suen TC, Belitskaya-Levy I, Tang MS, Toniolo P. Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review. Hum Reprod 2005;20:852-863. (Pubitemid 40667828)
21. Dimitrova IK, Richer JK, Rudolph MC, Spoelstra NS, Reno EM, Medina TM, Bradford AP. Gene expression profling of multiple leiomyomata uteri and matched normal tissue from a single patient. Fertil Steril 2009;91:2650-2663.
22. Catherino WH, Segars JH. Microarray analysis in fbroids: which gene list is the correct list? Fertil Steril 2003;80:293-294. (Pubitemid 36959784)
23. Chawla-Sarkar M, Lindner DJ, Liu YF, Williams BR, Sen GC, Silverman RH, Borden EC. Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis 2003;8: 237-249. (Pubitemid 36749609)
24. Rosebeck S, Leaman D W. Mitochondrial localization and pro-apoptotic efects of the interferon-inducible protein ISG12a. Apoptosis 2008;13:562-572.
25. Xu X, Shi YC, Gao W, Mao G, Zhao G, Agrawal S, Chisolm GM, et al. The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein. J Biol Chem 2002;277:48913-48922. (Pubitemid 35470861)
26. Byun DS, Cho K, Ryu BK, Lee MG, Kang MJ, Kim HR, Chi SG. Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas. Cancer Res 2003;63:7068-7075. (Pubitemid 37413441)
27. Lu R, Au WC, Yeow WS, Hageman N, Pitha PM. Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon snd silencing by hypermethylation. J Biol Chem 2000;275:31805-31812.
28. Reu FJ, Leaman D W, Maitra RR, Bae SI, Cherkassky L, Fox M W, Rempinski DR, et al. Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons. Cancer Res 2006;66:2785-2793.