-
1
-
-
70349634397
-
Guidelines for the diagnosis and treatment of pulmonary hypertension
-
Galiè N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2009; 34: 1219-1263.
-
(2009)
Eur Respir J
, vol.34
, pp. 1219-1263
-
-
Galiè, N.1
Hoeper, M.M.2
Humbert, M.3
-
3
-
-
0033817459
-
Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension
-
Lane KB, Machado RD, Pauciulo MW, et al. Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. Nat Genet 2000; 26: 81-84.
-
(2000)
Nat Genet
, vol.26
, pp. 81-84
-
-
Lane, K.B.1
Machado, R.D.2
Pauciulo, M.W.3
-
4
-
-
0033838125
-
Familial primary pulmonary hypertension (Gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
-
DOI 10.1086/303059
-
Deng Z, Morse JH, Slager SL, et al. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet 2000; 67: 737-744. (Pubitemid 30659603)
-
(2000)
American Journal of Human Genetics
, vol.67
, Issue.3
, pp. 737-744
-
-
Deng, Z.1
Morse, J.H.2
Slager, S.L.3
Cuervo, N.4
Moore, K.J.5
Venetos, G.6
Kalachikov, S.7
Cayanis, E.8
Fischer, S.G.9
Barst, R.J.10
Hodge, S.E.11
Knowles, J.A.12
-
5
-
-
67649573380
-
Genetics and genomics of pulmonary arterial hypertension
-
Machado RD, Eickelberg O, Elliott CG, et al. Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol 2009; 54: Suppl. 1, S32-S42.
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.SUPPL. 1
-
-
Machado, R.D.1
Eickelberg, O.2
Elliott, C.G.3
-
6
-
-
32544438253
-
BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension
-
Aldred MA, Vijayakrishnan J, James V, et al. BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension. Hum Mutat 2006; 27: 212-213.
-
(2006)
Hum Mutat
, vol.27
, pp. 212-213
-
-
Aldred, M.A.1
Vijayakrishnan, J.2
James, V.3
-
7
-
-
67649579669
-
Updated clinical classification of pulmonary hypertension
-
Simonneau G, Robbins IM, Beghetti M, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2009; 54: Suppl. 1, S43-S54.
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.SUPPL. 1
-
-
Simonneau, G.1
Robbins, I.M.2
Beghetti, M.3
-
8
-
-
0035163071
-
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
-
DOI 10.1086/316947
-
Machado RD, Pauciulo MW, Thomson JR, et al. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet 2001; 68: 92-102. (Pubitemid 32048364)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.1
, pp. 92-102
-
-
Machado, R.D.1
Pauciulo, M.W.2
Thomson, J.R.3
Lane, K.B.4
Morgan, N.V.5
Wheeler, L.6
Phillips III, J.A.7
Newman, J.8
Williams, D.9
Galie, N.10
Manes, A.11
McNeil, K.12
Yacoub, M.13
Mikhail, G.14
Rogers, P.15
Corris, P.16
Humbert, M.17
Donnai, D.18
Martensson, G.19
Tranebjaerg, L.20
Loyd, J.E.21
Trembath, R.C.22
Nichols, W.C.23
more..
-
9
-
-
0037046175
-
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
-
DOI 10.1161/01.CIR.0000012754.72951.3D
-
Atkinson C, Stewart S, Upton PD, et al. Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation 2002; 105: 1672-1678. (Pubitemid 34298611)
-
(2002)
Circulation
, vol.105
, Issue.14
, pp. 1672-1678
-
-
Atkinson, C.1
Stewart, S.2
Upton, P.D.3
Machado, R.4
Thomson, J.R.5
Trembath, R.C.6
Morrell, N.W.7
-
10
-
-
33644958041
-
Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension
-
DOI 10.1152/ajplung.00206.2005
-
Takahashi H, Goto N, Kojima Y, et al. Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2006; 290: L450-L458. (Pubitemid 43725089)
-
(2006)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.290
, Issue.3
-
-
Takahashi, H.1
Goto, N.2
Kojima, Y.3
Tsuda, Y.4
Morio, Y.5
Muramatsu, M.6
Fukuchi, Y.7
-
11
-
-
34247387518
-
Dysregulated bone morphogenetic protein signaling in monocrotaline- induced pulmonary arterial hypertension
-
DOI 10.1161/ATVBAHA.107.141200
-
Morty RE, Nejman B, Kwapiszewska G, et al. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol 2007; 27: 1072-1078. (Pubitemid 46641959)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.5
, pp. 1072-1078
-
-
Morty, R.E.1
Nejman, B.2
Kwapiszewska, G.3
Hecker, M.4
Zakrzewicz, A.5
Kouri, F.M.6
Peters, D.M.7
Dumitrascu, R.8
Seeger, W.9
Knaus, P.10
Schermuly, R.T.11
Eickelberg, O.12
-
12
-
-
75649127963
-
Bone morphogenetic protein receptors and signal transduction
-
Miyazono K, Kamiya Y, Morikawa M. Bone morphogenetic protein receptors and signal transduction. J Biochem 2010; 147: 35-51.
-
(2010)
J Biochem
, vol.147
, pp. 35-51
-
-
Miyazono, K.1
Kamiya, Y.2
Morikawa, M.3
-
13
-
-
67650188576
-
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells
-
Upton PD, Davies RJ, Trembath RC, et al. Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells. J Biol Chem 2009; 284: 15794-15804.
-
(2009)
J Biol Chem
, vol.284
, pp. 15794-15804
-
-
Upton, P.D.1
Davies, R.J.2
Trembath, R.C.3
-
14
-
-
9144219585
-
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
-
Harrison RE, Flanagan JA, Sankelo M, et al. Molecular and functional analysis identifies ALK-1 as the predominant cause ofpulmonary hypertension related to hereditary haemorrhagic telangiectasia. J Med Genet 2003; 40: 865-871. (Pubitemid 38117534)
-
(2003)
Journal of Medical Genetics
, vol.40
, Issue.12
, pp. 865-871
-
-
Harrison, R.E.1
Flanagan, J.A.2
Sankelo, M.3
Abdalla, S.A.4
Rowell, J.5
Machado, R.D.6
Elliott, C.G.7
Robbins, I.M.8
Olschewski, H.9
McLaughlin, V.10
Gruenig, E.11
Kermeen, F.12
Laitinen, T.13
Morrell, N.W.14
Halme, M.15
Raisanen-Sakolowski16
Trembath, R.C.17
-
15
-
-
77953067153
-
Clinical outcomes of pulmonary arterial hypertension in patients carrying an ACVRL1 (ALK1) mutation
-
Girerd B, Montani D, Coulet F, et al. Clinical outcomes of pulmonary arterial hypertension in patients carrying an ACVRL1 (ALK1) mutation. Am J Respir Crit Care Med 2010; 181: 851-861.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 851-861
-
-
Girerd, B.1
Montani, D.2
Coulet, F.3
-
16
-
-
39849084288
-
Implications of mutations of activin receptor-like kinase 1 gene (ALK1) in addition to bone morphogenetic protein receptor II gene (BMPR2) in children with pulmonary arterial hypertension
-
DOI 10.1253/circj.72.127
-
Fujiwara M, Yagi H, Matsuoka R, et al. Implications of mutations of activin receptor-like kinase 1 gene (ALK1) in addition to bone morphogenetic protein receptor II gene (BMPR2) in children with pulmonary arterial hypertension. Circ J 2008; 72: 127-133. (Pubitemid 351413340)
-
(2008)
Circulation Journal
, vol.72
, Issue.1
, pp. 127-133
-
-
Fujiwara, M.1
Yagi, H.2
Matsuoka, R.3
Akimoto, K.4
Furutani, M.5
Imamura, S.-I.6
Uehara, R.7
Nakayama, T.8
Takao, A.9
Nakazawa, M.10
Saji, T.11
-
17
-
-
66249125359
-
A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension
-
Shintani M, Yagi H, Nakayama T, et al. A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension. J Med Genet 2009; 46: 331-337.
-
(2009)
J Med Genet
, vol.46
, pp. 331-337
-
-
Shintani, M.1
Yagi, H.2
Nakayama, T.3
-
18
-
-
81255136932
-
Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension
-
Nasim MT, Ogo T, Ahmed M, et al. Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension. Hum Mutat 2011; 32: 1385-1389.
-
(2011)
Hum Mutat
, vol.32
, pp. 1385-1389
-
-
Nasim, M.T.1
Ogo, T.2
Ahmed, M.3
-
19
-
-
61349100681
-
Altered bone morphogenetic protein and transforming growth factor-β signaling in rat models of pulmonary hypertension: Potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease
-
Long L, Crosby A, Yang X, et al. Altered bone morphogenetic protein and transforming growth factor-β signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease. Circulation 2009; 119: 566-576.
-
(2009)
Circulation
, vol.119
, pp. 566-576
-
-
Long, L.1
Crosby, A.2
Yang, X.3
-
20
-
-
80051671703
-
Current therapeutics and practical management strategies for pulmonary arterial hypertension
-
Agarwal R, Gomberg-Maitland M. Current therapeutics and practical management strategies for pulmonary arterial hypertension. Am Heart J 2011; 162: 201-213.
-
(2011)
Am Heart J
, vol.162
, pp. 201-213
-
-
Agarwal, R.1
Gomberg-Maitland, M.2
-
21
-
-
79954624192
-
Alternatives to lung transplantation: Treatment of pulmonary arterial hypertension
-
Corris PA. Alternatives to lung transplantation: treatment of pulmonary arterial hypertension. Clin Chest Med 2011; 32: 399-410.
-
(2011)
Clin Chest Med
, vol.32
, pp. 399-410
-
-
Corris, P.A.1
-
22
-
-
77954758530
-
Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
-
Humbert M, Sitbon O, Chaouat A, et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 2010; 122: 156-163.
-
(2010)
Circulation
, vol.122
, pp. 156-163
-
-
Humbert, M.1
Sitbon, O.2
Chaouat, A.3
-
23
-
-
77954759389
-
Predicting survival in pulmonary arterial hypertension: Insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL)
-
Benza RL, Miller DP, Gomberg-Maitland M, et al. Predicting survival in pulmonary arterial hypertension: insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL). Circulation 2010; 122: 164-172.
-
(2010)
Circulation
, vol.122
, pp. 164-172
-
-
Benza, R.L.1
Miller, D.P.2
Gomberg-Maitland, M.3
-
24
-
-
77955953602
-
Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension
-
Humbert M, Sitbon O, Yaïci A, et al. Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension. Eur Respir J 2010; 36: 549-555.
-
(2010)
Eur Respir J
, vol.36
, pp. 549-555
-
-
Humbert, M.1
Sitbon, O.2
Yaïci, A.3
-
25
-
-
84856721781
-
Targeted gene delivery of BMPR2 attenuates pulmonary hypertension
-
Reynolds AM, Holmes MD, Danilov SM, et al. Targeted gene delivery of BMPR2 attenuates pulmonary hypertension. Eur Respir J 2012; 39: 329-343.
-
(2012)
Eur Respir J
, vol.39
, pp. 329-343
-
-
Reynolds, A.M.1
Holmes, M.D.2
Danilov, S.M.3
|