Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis

Clinical Rheumatology

Volumn 31, Issue 2, 2012, Pages 251-257

  Ogasawara, Michihiro ^a   Tamura, Naoto ^a   Kageyama, Michiaki ^a   Onuma, Shin ^a   Kusaoi, Makio ^a   Toyama, Shoko ^a   Sekiya, Fumio ^a   Matsudaira, Ran ^a   Nawata, Masuyuki ^a   Tada, Kurisu ^a   Matsushita, Masakazu ^a   Kempe, Kazuo ^a   Amano, Hirofumi ^a   Morimoto, Shinji ^a   Yamaji, Ken ^a   Takasaki, Yoshinari ^a  

^a JUNTENDO UNIVERSITY   (Japan)

Author keywords

Combination therapy; Rheumatoid arthritis; Second line DMARDs; Tacrolimus

Indexed keywords

ANTIBIOTIC AGENT; BUCILLAMINE; CORTICOSTEROID; METHOTREXATE; SALAZOSULFAPYRIDINE; TACROLIMUS;

ADULT; AGED; ARTICLE; BACTERIAL ENDOCARDITIS; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RHEUMATOID ARTHRITIS;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CYSTEINE; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; METHOTREXATE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SULFASALAZINE; TACROLIMUS; TREATMENT OUTCOME;

EID: 84856707447     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-011-1810-6     Document Type: Article

References (13)

1. D Furst K Saag M Fleischmann Y Sherrer J Block T Schnitzer, et al. 2002 Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate: a six-month, double-blind, randomized, dose-ranging study Arthritis Rheum 46 2020 2028 12209503 10.1002/art.10427 1:CAS:528:DC%2BD38XmvFOqtL8%3D
2. D Yocum D Furst J Kaine A Baldassare J Stevenson M Borton, et al. 2003 Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: a double-blind trial Arthritis Rheum 48 3328 3337 14673984 10.1002/art.11363 1:CAS:528:DC%2BD2cXkt12ktg%3D%3D (Pubitemid 37531899)
3. D Yocum D Furst W Bensen F Burch M Borton L Mengle-Gaw, et al. 2004 Safety of tacrolimus in patients with rheumatoid arthritis: long-term experience Rheumatology (Oxford) 43 992 999 10.1093/rheumatology/keh155 1:CAS:528:DC%2BD2cXlsl2ku7w%3D (Pubitemid 39144446)
4. S Kawai H Hashimoto H Kondo T Murayama T Kiuchi T Abe 2006 Comparison of tacrolimus and mizoribine in a randomized, double-blind controlled study in patients with rheumatoid arthritis J Rheumatol 33 2153 2161 16960930 1:CAS:528:DC%2BD28Xhtlemu77O (Pubitemid 44749772)
5. S Kawai K Yamamoto 2006 Safety of tacrolimus, an immunosuppressive agent, in the treatment of rheumatoid arthritis in elderly patients Rheumatology (Oxford) 45 441 444 10.1093/rheumatology/kei172 1:CAS:528:DC%2BD28Xis1Gltr0%3D
6. S Kawai K Tanaka I Ohno K Utsunomiya Y Seino 2008 Safety of long-term tacrolimus therapy for rheumatoid arthritis: an open-label, uncontrolled study in non-elderly patients Mod Rheumatol 18 345 353 18427723 10.1007/s10165-008- 0058-8 1:CAS:528:DC%2BD1cXpsVGnsbo%3D
7. H Kondo T Abe H Hashimoto S Uchida S Irimajiri M Hara, et al. 2004 Efficacy and safety of tacrolimus (FK506) in treatment of rheumatoid arthritis: a randomized, double blind, placebo controlled dose-finding study J Rheumatol 31 243 251 14760792 1:CAS:528:DC%2BD2cXhslehtb8%3D (Pubitemid 38160744)
8. K Suzuki H Kameda K Amano H Nagasawa H Takei N Sekiguchi, et al. 2009 Single center prospective study of tacrolimus efficacy and safety in treatment of rheumatoid arthritis Rheumatol Int 29 431 436 19127365 10.1007/s00296-008- 0833-z 1:CAS:528:DC%2BD1MXhsFWnurw%3D
9. J Kremer J Habros K Kolba J Kaine M Borton L Mengle-Gaw, et al. 2003 Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study Arthritis Rheum 48 2763 2768 14558080 10.1002/art.11257 1:CAS:528:DC%2BD3sXpt1Sku7g%3D (Pubitemid 37280603)
10. Y Morita Y Sasae T Sakuta M Satoh T Sasaki N Kashihara 2008 Efficacy of low-dose tacrolimus added to methotrexate in patients with rheumatoid arthritis in Japan: a retrospective study Mod Rheumatol 18 379 384 18463945 10.1007/s10165-008-0071-y 1:CAS:528:DC%2BD1cXpsVGnsbY%3D
11. F Arnett S Edworthy D Bloch D McShane J Fries N Cooper, et al. 1988 The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 315 324 3358796 10.1002/art.1780310302 1:STN:280:DyaL1c7pt1Ohsg%3D%3D (Pubitemid 18091653)
12. O Steinbrocker CH Traeger RC Batterman 1949 Therapeutic criteria in rheumatoid arthritis J Am Med Assoc 140 659 662 18150288 10.1001/jama.1949. 02900430001001 1:STN:280:DyaH1M%2FltFyltw%3D%3D
13. J O'Dell R Leff G Paulsen C Haire J Mallek P Eckhoff, et al. 2002 Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications: results of a two-year, randomized, double-blind, placebo-controlled trial Arthritis Rheum 46 1164 1170 12115219 10.1002/art.10228 (Pubitemid 34525821)