-
1
-
-
0001733527
-
On oophorectomy in cancer of the breast
-
Boyd S. On oophorectomy in cancer of the breast. BMJ. 1900;2:1161-1167.
-
(1900)
BMJ
, vol.2
, pp. 1161-1167
-
-
Boyd, S.1
-
2
-
-
1842295624
-
Prostatic cancer treated by orchiectomy; The five year results
-
Huggins C. Prostatic cancer treated by orchiectomy; the five year results. JAMA. 1946;15:576-581.
-
(1946)
JAMA
, vol.15
, pp. 576-581
-
-
Huggins, C.1
-
3
-
-
78651047933
-
Adrenalectomy and oophorectomy in treatment of advanced carcinoma of the breast
-
Huggins C, Dao TL. Adrenalectomy and oophorectomy in treatment of advanced carcinoma of the breast. JAMA. 1953;18:1388-1394.
-
(1953)
JAMA
, vol.18
, pp. 1388-1394
-
-
Huggins, C.1
Dao, T.L.2
-
4
-
-
0019857013
-
A randomized trial comparing surgical adrenalectomy with aminoglutethimide plus hydrocortisone in women with advanced breast cancer
-
Santen RJ, Worgul TJ, Samojlik E, et al. A randomized trial comparing surgical adrenalectomy with aminoglutethimide plus hydrocortisone in women with advanced breast cancer. N Engl J Med. 1981;305:545-551. (Pubitemid 12201131)
-
(1981)
New England Journal of Medicine
, vol.305
, Issue.10
, pp. 545-551
-
-
Santen, R.J.1
Worgul, T.J.2
Samojlik, E.3
-
5
-
-
0017153067
-
Regression of prostate cancer metastasis by high doses of diethylsilbestrol phosphate
-
Susan LP, Roth RB, Adkins WC. Regression of prostate cancer metastasis by high doses of diethylsilbestrol phosphate. Urology. 1976;7:598-601.
-
(1976)
Urology
, vol.7
, pp. 598-601
-
-
Susan, L.P.1
Roth, R.B.2
Adkins, W.C.3
-
6
-
-
0021721387
-
Leuprolide versus diethylstilbestrol for metastatic prostate cancer. The leuprolide study group. The leuprolide study group
-
The Leuprolide Study Group. Leuprolide versus diethylstilbestrol for metastatic prostate cancer. The Leuprolide Study Group. N Engl J Med. 1984;311:1281-1286.
-
(1984)
N Engl J Med
, vol.311
, pp. 1281-1286
-
-
-
7
-
-
10344260143
-
A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate carcinoma: Analysis of time to progression
-
DOI 10.1002/(SICI)1097-0142(19961115)78:10<2164::AID-CNCR18>3.0. CO;2-X
-
Schellhammer PF, Sharifi R, Block NL, et al. A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormoneYreleasing hormone analogue therapy, in patients with advanced prostate carcinoma. Analysis of time to progression. CASODEX Combination Study Group. Cancer. 1996;78:2164-2169. (Pubitemid 26367610)
-
(1996)
Cancer
, vol.78
, Issue.10
, pp. 2164-2169
-
-
Schellhammer, P.F.1
Sharifi, R.2
Block, N.L.3
Soloway, M.S.4
Venner, P.M.5
Patterson, A.L.6
Sarosdy, M.F.7
Vogelzang, N.J.8
Chen, Y.9
Kolvenbag, G.J.C.M.10
-
8
-
-
0032569831
-
Tamoxifen in the treatment of breast cancer
-
DOI 10.1056/NEJM199811263392207
-
Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998;339:1609-1618. (Pubitemid 28536137)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.22
, pp. 1609-1618
-
-
Osborne, C.K.1
-
9
-
-
0037157603
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
-
DOI 10.1016/S0140-6736(02)09088-8
-
Baum M, Budzar AU, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet. 2002;359:2131-2139. (Pubitemid 34694019)
-
(2002)
Lancet
, vol.359
, Issue.9324
, pp. 2131-2139
-
-
Baum, M.1
Buzdar, A.U.2
Cuzick, J.3
Forbes, J.4
Houghton, J.5
Klijn, J.G.M.6
Sahmoud, T.7
-
10
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med. 2011;364:1995-2005.
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
11
-
-
79951665862
-
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders
-
Miller WL, Auchus RJ. The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders. Endocr Rev. 2011;32:81-151.
-
(2011)
Endocr Rev
, vol.32
, pp. 81-151
-
-
Miller, W.L.1
Auchus, R.J.2
-
12
-
-
0031808778
-
Lessons from congenital lipoid adrenal hyperplasia
-
Miller WL. Lessons from congenital lipoid adrenal hyperplasia. Curr Opin Endocrinol Diabetes. 1998;5:155-161. (Pubitemid 28311501)
-
(1998)
Current Opinion in Endocrinology and Diabetes
, vol.5
, Issue.3
, pp. 155-161
-
-
Miller, W.L.1
-
13
-
-
0025728051
-
Intracrinology
-
Labrie F. Intracrinology. Mol Cell Endocrinol. 1991;78:113-118.
-
(1991)
Mol Cell Endocrinol
, vol.78
, pp. 113-118
-
-
Labrie, F.1
-
14
-
-
0026544312
-
Androgen resistanceVthe clinical and molecular spectrum
-
Griffin JE. Androgen resistanceVthe clinical and molecular spectrum. N Engl J Med. 1992;326:611-618.
-
(1992)
N Engl J Med
, vol.326
, pp. 611-618
-
-
Griffin, J.E.1
-
15
-
-
0031731177
-
Early steps in androgen biosynthesis: From cholesterol to DHEA
-
DOI 10.1016/S0950-351X(98)80461-8
-
Miller WL. Early steps in androgen biosynthesis: from cholesterol to DHEA. Baillieres Clin Endocrinol Metab. 1998;12:67-81. (Pubitemid 28495390)
-
(1998)
Bailliere's Clinical Endocrinology and Metabolism
, vol.12
, Issue.1
, pp. 67-81
-
-
Miller, W.L.1
-
16
-
-
0028104418
-
The purification, cloning and expression of a novel luteinizing hormoneYinduced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR
-
Clark BJ, Wells J, King SR, et al. The purification, cloning and expression of a novel luteinizing hormoneYinduced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J Biol Chem. 1994;269:28314-28322.
-
(1994)
J Biol Chem
, vol.269
, pp. 28314-28322
-
-
Clark, B.J.1
Wells, J.2
King, S.R.3
-
17
-
-
0034064138
-
Structure and lipid transport mechanism of a StAr-related domain
-
DOI 10.1038/75192
-
Tsujishita Y, Hurley JH. Structure and lipid transport mechanism of a StAR-related domain. Nat Struct Biol. 2000;7:408-414. (Pubitemid 30250006)
-
(2000)
Nature Structural Biology
, vol.7
, Issue.5
, pp. 408-414
-
-
Tsujishita, Y.1
Hurley, J.H.2
-
18
-
-
0037007628
-
Rapid regulation of steroidogenesis by mitochondrial protein import
-
DOI 10.1038/417087a
-
Bose H, Lingappa VR, Miller WL. Rapid regulation of steroidogenesis by mitochondrial protein import. Nature. 2002;417:87-91. (Pubitemid 34498821)
-
(2002)
Nature
, vol.417
, Issue.6884
, pp. 87-91
-
-
Bose, H.S.1
Lingappat, V.R.2
Miller, W.L.3
-
19
-
-
0031453141
-
Phosphorylation of steroidogenic acute regulatory protein (StAR) modulates its steroidogenic activity
-
DOI 10.1074/jbc.272.51.32656
-
Arakane F, King SR, Du Y, et al. Phosphorylation of steroidogenic acute regulatory protein (StAR) modulates its steroidogenic activity. J Biol Chem. 1997;272:32656-32662. (Pubitemid 28011957)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.51
, pp. 32656-32662
-
-
Arakane, F.1
King, S.R.2
Du, Y.3
Kallen, C.B.4
Walsh, L.P.5
Watari, H.6
Stocco, D.M.7
Strauss III, J.F.8
-
20
-
-
0028944669
-
Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis
-
Lin D, Sugawara T, Strauss JF III, et al. Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis. Science. 1995;267:1828-1831.
-
(1995)
Science
, vol.267
, pp. 1828-1831
-
-
Lin, D.1
Sugawara, T.2
Strauss III, J.F.3
-
21
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
Montgomery RB, Mostaghel EA, Vessella R, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 2008;68:4447-4454.
-
(2008)
Cancer Res
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
-
22
-
-
80054021222
-
Intratumoral de novo steroid synthesis activates androgen receptor in castration resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
-
Cai C, Chen S, Ng P, et al. Intratumoral de novo steroid synthesis activates androgen receptor in castration resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Res. 2011;71:6503-6513.
-
(2011)
Cancer Res
, vol.71
, pp. 6503-6513
-
-
Cai, C.1
Chen, S.2
Ng, P.3
-
23
-
-
76249096762
-
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
-
Hofland J, van Weerden WM, Dits NF, et al. Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res. 2010;70:1256-1264.
-
(2010)
Cancer Res
, vol.70
, pp. 1256-1264
-
-
Hofland, J.1
Van Weerden, W.M.2
Dits, N.F.3
-
24
-
-
0027446505
-
The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature
-
Nelson DR, Kamataki T, Waxman DJ, et al. The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 1993;12:1-51. (Pubitemid 23064489)
-
(1993)
DNA and Cell Biology
, vol.12
, Issue.1
, pp. 1-51
-
-
Nelson, D.R.1
Kamataki, T.2
Waxman, D.J.3
Guengerich, F.P.4
Estabrook, R.W.5
Feyereisen, R.6
Gonzalez, F.J.7
Coon, M.J.8
Gunsalus, I.C.9
Gotoh, O.10
Okuda, K.11
Nebert, D.W.12
-
25
-
-
3543068881
-
Human 17β-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells
-
DOI 10.1016/j.abb.2004.05.023, PII S0003986104003030
-
Khan N, Sharma KK, Andersson S, et al. Human 17A-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells. Arch Biochem Biophys. 2004;429:50-59. (Pubitemid 39022591)
-
(2004)
Archives of Biochemistry and Biophysics
, vol.429
, Issue.1
, pp. 50-59
-
-
Khan, N.1
Sharma, K.K.2
Andersson, S.3
Auchus, R.J.4
-
26
-
-
60249092664
-
Androgens, estrogens, and hydroxysteroid dehydrogenases
-
Mizrachi D, Auchus RJ. Androgens, estrogens, and hydroxysteroid dehydrogenases. Mol Cell Endocrinol. 2009;301:37-42.
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 37-42
-
-
Mizrachi, D.1
Auchus, R.J.2
-
27
-
-
0027930787
-
Male pseudohermaphroiditism caused by mutations of testicular 17A-hydroxysteroid dehydrogenase 3
-
Geissler WM, Davis DL, Wu L, et al. Male pseudohermaphroiditism caused by mutations of testicular 17A-hydroxysteroid dehydrogenase 3. Nat Genet. 1994;7:34-39.
-
(1994)
Nat Genet
, vol.7
, pp. 34-39
-
-
Geissler, W.M.1
Davis, D.L.2
Wu, L.3
-
28
-
-
0027225486
-
Expression cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity
-
Wu L, Einstein M, Geissler WM, et al. Expression cloning and characterization of human 17A-hydrosteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity. J Biol Chem. 1993;268:12964-12969. (Pubitemid 23182471)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.17
, pp. 12964-12969
-
-
Wu, L.1
Einstein, M.2
Geissler, W.M.3
Chan, H.K.4
Elliston, K.O.5
Andersson, S.6
-
29
-
-
0029586941
-
Structure-function relationships and molecular genetics of the 3β-hydroxysteroid dehydrogenase gene family
-
DOI 10.1016/0960-0760(95)00198-0
-
Simard J, Sanchez R, Durocher F, et al. Structure-function relationships and molecular genetics of the 3A-hydroxysteroid dehydrogenase gene family. J Steroid Biochem Mol Biol. 1995;55:489-505. (Pubitemid 26022382)
-
(1995)
Journal of Steroid Biochemistry and Molecular Biology
, vol.55
, Issue.5-6
, pp. 489-505
-
-
Simard, J.1
Sanchez, R.2
Durocher, F.3
Rheaume, E.4
Turgeon, C.5
Labrie, Y.6
Luu-The, V.7
Mebarki, F.8
Morel, Y.9
De Launoit, Y.10
Labrie, F.11
-
30
-
-
0033673885
-
Role of 17A-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues
-
Labrie F, Luu-The V, Lin SX, et al. Role of 17A-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues. Trends Endocrinol Metab. 2000;11:421-427.
-
(2000)
Trends Endocrinol Metab
, vol.11
, pp. 421-427
-
-
Labrie, F.1
Luu-The, V.2
Lin, S.X.3
-
31
-
-
0035103197
-
Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members
-
DOI 10.1210/en.142.2.778
-
Turgeon D, Carrier JS, Levesque E, et al. Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members. Endocrinology. 2001;142:778-787. (Pubitemid 32222427)
-
(2001)
Endocrinology
, vol.142
, Issue.2
, pp. 778-787
-
-
Turgeon, D.1
Carrier, J.-S.2
Levesque, E.3
Hum, D.W.4
Belanger, A.5
-
32
-
-
0032519431
-
Genetic predisposition to the metabolism of irinotecan (CPT-11): Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
-
Iyer L, King CD, Whitington PF, et al. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest. 1998;101:847-854. (Pubitemid 28096082)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.4
, pp. 847-854
-
-
Iyer, L.1
King, C.D.2
Whitington, P.F.3
Green, M.D.4
Roy, S.K.5
Tephly, T.R.6
Coffman, B.L.7
Ratain, M.J.8
-
33
-
-
0029872530
-
Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients
-
DOI 10.1210/jc.81.4.1460
-
Pasqualini JR, Chetrite G, Blacker C, et al. Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J Clin Endocrinol Metab. 1996;81:1460-1464. (Pubitemid 26118577)
-
(1996)
Journal of Clinical Endocrinology and Metabolism
, vol.81
, Issue.4
, pp. 1460-1464
-
-
Pasqualini, J.R.1
Chetrite, G.2
Blacker, C.3
Feinstein, M.-C.4
Delalonde, L.5
Talbi, M.6
Maloche, C.7
-
34
-
-
33744951313
-
Serum 21-deoxycortisol, 17-hydroxyprogesterone, and 11-deoxycortisol in classic congenital adrenal hyperplasia: Clinical and hormonal correlations and identification of patients with 11β-hydroxylase deficiency among a large group with alleged 21-hydroxylase deficiency
-
DOI 10.1210/jc.2005-1890
-
Tonetto-Fernandes V, Lemos-Marini SH, Kuperman H, et al. Serum 21-deoxycortisol, 17-hydroxyprogesterone, and 11-deoxycortisol in classic congenital adrenal hyperplasia: clinical and hormonal correlations and identification of patients with 11A-hydroxylase deficiency among a large group with alleged 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2006;91:2179-2184. (Pubitemid 43855002)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.6
, pp. 2179-2184
-
-
Tonetto-Fernandes, V.1
Lemos-Marini, S.H.V.2
Kuperman, H.3
Ribeiro-Neto, L.M.4
Verreschi, I.T.N.5
Kater, C.E.6
-
36
-
-
80051963331
-
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
-
Chang KH, Li R, Papari-Zareei M, et al. Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2011;108:13728-13733.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 13728-13733
-
-
Chang, K.H.1
Li, R.2
Papari-Zareei, M.3
-
37
-
-
7444233759
-
The backdoor pathway to dihydrotestosterone
-
DOI 10.1016/j.tem.2004.09.004, PII S1043276004002140
-
Auchus RJ. The backdoor pathway to dihydrotestosterone. Trends Endocrinol Metab. 2004;15:432-438. (Pubitemid 39440726)
-
(2004)
Trends in Endocrinology and Metabolism
, vol.15
, Issue.9
, pp. 432-438
-
-
Auchus, R.J.1
-
38
-
-
0037317265
-
5α-androstane-3α,17β-diol is formed in tammar wallaby pouch young testes by a pathway involving 5α-pregnane-3α,17α- diol-20-one as a key intermediate
-
DOI 10.1210/en.2002-220721
-
Wilson JD, Auchus RJ, Leihy MW, et al. 5α-Androstane-3α,17A- diol is formed in tammar wallaby pouch young testes by a pathway involving 5α-pregnane-3α,17α-diol-20-one as a key intermediate. Endocrinology. 2003;144:575-580. (Pubitemid 36205230)
-
(2003)
Endocrinology
, vol.144
, Issue.2
, pp. 575-580
-
-
Wilson, J.D.1
Auchus, R.J.2
Leihy, M.W.3
Guryev, O.L.4
Estabrook, R.W.5
Osborn, S.M.6
Shaw, G.7
Renfree, M.B.8
-
39
-
-
0036514773
-
The marsupial model for male phenotypic development
-
DOI 10.1016/S1043-2760(01)00525-2, PII S1043276001005252
-
Wilson JD, Shaw G, Leihy ML, et al. The marsupial model for male phenotypic development. Trends Endocrinol Metab. 2002;13:78-83. (Pubitemid 36740451)
-
(2002)
Trends in Endocrinology and Metabolism
, vol.13
, Issue.2
, pp. 78-83
-
-
Wilson, J.D.1
Shaw, G.2
Leihy, M.L.3
Renfree, M.B.4
-
40
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009;324:787-790.
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
-
41
-
-
34247523157
-
Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: Results from a Cancer and Leukemia Group B study
-
DOI 10.1158/1078-0432.CCR-06-2344
-
Ryan CJ, Halabi S, Ou SS, et al. Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: results from a cancer and leukemia group B study. Clin Cancer Res. 2007;13:2030-2037. (Pubitemid 46649869)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.7
, pp. 2030-2037
-
-
Ryan, C.J.1
Halabi, S.2
Ou, S.-S.3
Vogelzang, N.J.4
Kantoff, P.5
Small, E.J.6
-
42
-
-
0025150875
-
A phase II randomized trial of megestrol acetate or dexamethasone in the treatment of hormonally refractory advanced carcinioma of the prostate
-
DOI 10.1002/1097-0142(19900815)66:4<655::AID-CNCR2820660409>3.0. CO;2-P
-
Patel SR, Kvols LK, Hahn RG, et al. A phase II randomized trial of megestrol acetate or dexamethasone in the treatment of hormonally refractory advanced carcinoma of the prostate. Cancer. 1990;66:655-658. (Pubitemid 20281305)
-
(1990)
Cancer
, vol.66
, Issue.4
, pp. 655-658
-
-
Patel, S.R.1
Kvols, L.K.2
Hahn, R.G.3
Windschitl, H.4
Levitt, R.5
Therneau, T.6
-
43
-
-
53749090666
-
Phase i clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
Attard G, Reid AH, Yap TA, et al. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol. 2008;26:463-4571.
-
(2008)
J Clin Oncol
, vol.26
, pp. 463-4571
-
-
Attard, G.1
Reid, A.H.2
Yap, T.A.3
-
44
-
-
68949094223
-
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
Attard G, Reid AH, A'Hern R, et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol. 2009;27:3742-3748.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'hern, R.3
-
45
-
-
3042784503
-
17,20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer
-
O'Donnell A, Judson I, Dowsett M, et al. Hormonal impact of the 17α-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. Br J Cancer. 2004;90:2317-2325. (Pubitemid 38961894)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.12
, pp. 2317-2325
-
-
O'Donnell, A.1
Judson, I.2
Dowsett, M.3
Raynaud, F.4
Dearnaley, D.5
Mason, M.6
Harland, S.7
Robbins, A.8
Halbert, G.9
Nutley, B.10
Jarman, M.11
-
46
-
-
0035032081
-
The genetics, pathophysiology, and management of human deficiencies of P450c17
-
Auchus RJ. The genetics, pathophysiology, and management of human deficiencies of P450c17. Endocrinol Metab Clin North Am. 2001;30:101-119. (Pubitemid 32381716)
-
(2001)
Endocrinology and Metabolism Clinics of North America
, vol.30
, Issue.1
, pp. 101-119
-
-
Auchus, R.J.1
-
47
-
-
0842291524
-
Two Prevalent CYP17 Mutations and Genotype-Phenotype Correlations in 24 Brazilian Patients with 17-Hydroxylase Deficiency
-
DOI 10.1210/jc.2003-031021
-
Costa-Santos M, Kater CE, Auchus RJ. Two prevalent CYP17 mutations and genotype-phenotype correlations in 24 Brazilian patients with 17-hydroxylase deficiency. J Clin Endocrinol Metab. 2004;89:49-60. (Pubitemid 38183859)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.1
, pp. 49-60
-
-
Costa-Santos, M.1
Kater, C.E.2
Auchus, R.J.3
-
49
-
-
84878522002
-
Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer
-
In press
-
Attard G, Reid AHM, Auchus RJ, et al. Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer. J Clin Endocrinol Metab. In press.
-
J Clin Endocrinol Metab
-
-
Attard, G.1
Ahm, R.2
Auchus, R.J.3
-
50
-
-
0029287476
-
Endocrine therapy of prostate cancer: Optimal form and timing
-
Labrie F. Endocrine therapy of prostate cancer: optimal form and timing. J Clin Endocrinol Metab. 1995;80:1066-1071.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 1066-1071
-
-
Labrie, F.1
-
51
-
-
33644881888
-
Aldo-keto reductase (AKR) 1C3: Role in prostate disease and the development of specific inhibitors
-
Penning TM, Steckelbroeck S, Bauman DR, et al. Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitors. Mol Cell Endocrinol. 2006;248:182-191.
-
(2006)
Mol Cell Endocrinol
, vol.248
, pp. 182-191
-
-
Penning, T.M.1
Steckelbroeck, S.2
Bauman, D.R.3
-
52
-
-
78651492301
-
Getting from here to there''Vmechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer
-
Sharifi N, McPhaul MJ, Auchus RJ. ''Getting from here to there''Vmechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer. J Investig Med.2010;58:938-944.
-
(2010)
J Investig Med
, vol.58
, pp. 938-944
-
-
Sharifi, N.1
McPhaul, M.J.2
Auchus, R.J.3
-
53
-
-
0020035703
-
Origin of serum estradiol in postmenopausal women
-
Judd HL, Shamonki IM, Frumar AM, et al. Origin of serum estradiol in postmenopausal women. Obstet Gynecol. 1982;59:680-686. (Pubitemid 12107424)
-
(1982)
Obstetrics and Gynecology
, vol.59
, Issue.6
, pp. 680-686
-
-
Judd, H.L.1
Shamonki, I.M.2
Frumar, A.M.3
Lagasse, L.D.4
-
54
-
-
0028332035
-
Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis
-
DOI 10.1210/er.15.3.342
-
Simpson ER, Mahendroo MS, Means GD, et al. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr Rev. 1994;15:342-355. (Pubitemid 24180792)
-
(1994)
Endocrine Reviews
, vol.15
, Issue.3
, pp. 342-355
-
-
Simpson, E.R.1
Mahendroo, M.S.2
Means, G.D.3
Kilgore, M.W.4
Hinshelwood, M.M.5
Graham-Lorence, S.6
Amarneh, B.7
Ito, Y.8
Fisher, C.R.9
Michael, M.D.10
Mendelson, C.R.11
Bulun, S.E.12
-
55
-
-
0031027033
-
Aromatase activity and expression in breast cancer and benign breast tissue stromal cells
-
DOI 10.1210/jc.82.1.200
-
Santner SJ, Pauley RJ, Tait L, et al. Aromatase activity and expression in breast cancer and benign breast tissue stromal cells. J Clin Endocrinol Metab. 1997;82:200-208. (Pubitemid 27021297)
-
(1997)
Journal of Clinical Endocrinology and Metabolism
, vol.82
, Issue.1
, pp. 200-208
-
-
Santner, S.J.1
Pauley, R.J.2
Tait, L.3
Kaseta, J.4
Santen, R.J.5
-
56
-
-
37849052460
-
The breast cancer continuum in hormone-receptorYpositive breast cancer in postmenopausal women: Evolving management options focusing on aromatase inhibitors
-
Rugo HS. The breast cancer continuum in hormone-receptorYpositive breast cancer in postmenopausal women: evolving management options focusing on aromatase inhibitors. Ann Oncol. 2008;19:16-27.
-
(2008)
Ann Oncol
, vol.19
, pp. 16-27
-
-
Rugo, H.S.1
-
57
-
-
79953248180
-
Premenopausal hormone-responsive breast cancer with extensive axillary nodes involvement: Total estrogen blockade and chemotherapy
-
Recchia F, Candeloro G, Necozione S, et al. Premenopausal hormone-responsive breast cancer with extensive axillary nodes involvement: total estrogen blockade and chemotherapy. Anticancer Res. 2011;31:671-676.
-
(2011)
Anticancer Res
, vol.31
, pp. 671-676
-
-
Recchia, F.1
Candeloro, G.2
Necozione, S.3
-
58
-
-
33745005540
-
Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: Caution and suggested guidelines
-
DOI 10.1200/JCO.2005.05.3694
-
Smith IE, Dowsett M, Yap YS, et al. Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines. J Clin Oncol. 2006;24:2444-2447. (Pubitemid 46630620)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2444-2447
-
-
Smith, I.E.1
Dowsett, M.2
Yap, Y.-S.3
Walsh, G.4
Lonning, P.E.5
Santen, R.J.6
Hayes, D.7
-
59
-
-
79151479122
-
Which factors should be taken into account in perimenopausal women with early breast cancer who may become eligible for an aromatase inhibitor? Recommendations of an expert panel
-
Ortmann O, Pagani O, Jones A, et al. Which factors should be taken into account in perimenopausal women with early breast cancer who may become eligible for an aromatase inhibitor? Recommendations of an expert panel. Cancer Treat Rev. 2011;37:97-104.
-
(2011)
Cancer Treat Rev
, vol.37
, pp. 97-104
-
-
Ortmann, O.1
Pagani, O.2
Jones, A.3
-
60
-
-
43249113162
-
Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer
-
Dixon JM, Renshaw L, Young O, et al. Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer. J Clin Oncol. 2008;26:1671-1676.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1671-1676
-
-
Dixon, J.M.1
Renshaw, L.2
Young, O.3
-
61
-
-
20044382779
-
American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: Status report 2004
-
DOI 10.1200/JCO.2005.09.121
-
Winer EP, Hudis C, Burstein HJ, et al. American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptorYpositive breast cancer: status report 2004. J Clin Oncol. 2005;23:619-629. (Pubitemid 46224240)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.3
, pp. 619-629
-
-
Winer, E.P.1
Hudis, C.2
Burstein, H.J.3
Wolff, A.C.4
Pritchard, K.I.5
Ingle, J.N.6
Chlebowski, R.T.7
Gelber, R.8
Edge, S.B.9
Gralow, J.10
Cobleigh, M.A.11
Mamounas, E.P.12
Goldstein, L.J.13
Whelan, T.J.14
Powles, T.J.15
Bryant, J.16
Perkins, C.17
Perotti, J.18
Braun, S.19
Langer, A.S.20
Browman, G.P.21
Somerfield, M.R.22
more..
-
62
-
-
0042071592
-
Androgen receptors frequently are expressed in breast carcinomas: Potential relevance to new therapeutic strategies
-
DOI 10.1002/cncr.11532
-
Moinfar F, Okcu M, Tsybrovskyy O, et al. Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies. Cancer. 2003;98:703-711. (Pubitemid 36959265)
-
(2003)
Cancer
, vol.98
, Issue.4
, pp. 703-711
-
-
Moinfar, F.1
Okcu, M.2
Tsybrovskyy, O.3
Regitnig, P.4
Lax, S.F.5
Weybora, W.6
Ratschek, M.7
Tavassoli, F.A.8
Denk, H.9
-
63
-
-
67349101669
-
The androgen metabolite 5α-androstane-3A,17A-diol (3AAdiol) induces breast cancer growth via estrogen receptor: Implications for aromatase inhibitor resistance
-
Sikora MJ, Cordero KE, Larios JM, et al. The androgen metabolite 5α-androstane-3A,17A-diol (3AAdiol) induces breast cancer growth via estrogen receptor: implications for aromatase inhibitor resistance. Breast Cancer Res Treat. 2009;115:289-296.
-
(2009)
Breast Cancer Res Treat
, vol.115
, pp. 289-296
-
-
Sikora, M.J.1
Cordero, K.E.2
Larios, J.M.3
|