Use of procalcitonin to guide duration of antimicrobial therapy in intensive care units: Proceed with caution

Clinical Infectious Diseases

Volumn 54, Issue 4, 2012, Pages 578-

  Manian, Farrin A ^a  

^a MERCY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; PROCALCITONIN;

ANTIBIOTIC THERAPY; DRUG USE; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; LETTER; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TREATMENT DURATION;

ANTI-INFECTIVE AGENTS; BACTERIAL INFECTIONS; CALCITONIN; HUMANS; PROTEIN PRECURSORS;

EID: 84856695336     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cir888     Document Type: Letter

References (6)

1. Agarwal R, Schwartz DN. Procalcitonin to guide duration of antimicrobial therapy in intensive care units: a systematic review. Clin Infect Dis 2011; 53:379-87.
2. Simon L, Gauvin F, Amre DK, et al. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis 2004; 39:206-17. (Pubitemid 38971491)
3. Stucker F, Hermann F, Graf JD, et al. Procalcitonin and infection in elderly patients. J Am Geriatr Soc 2005; 53:1392-5. (Pubitemid 41602486)
4. Gaini S, Koldkjaer OG, Pedersen C, et al. Procalcitonin, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study. Crit Care 2006; 10:R53.
5. Tang BM, Eslick GD, Craig JC, et al. Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: a systematic review and metaanalysis. Lancet Infect Dis 2007; 7:210-7. (Pubitemid 46274517)
6. Jensen JU, Hein L, Lundgren B, et al. Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial. Crit Care Med 2011; 39:2048-58.