No effect of maternal micronutrient supplementation on early childhood growth in rural western China: 30 month follow-up evaluation of a double blind, cluster randomized controlled trial

European Journal of Clinical Nutrition

Volumn 66, Issue 2, 2012, Pages 261-268

  Wang, W ^a   Yan, H ^a   Zeng, L ^a   Cheng, Y ^a   Wang, D ^b   Li, Q ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

early childhood growth; folic acid; iron folic acid; multi micronutrient; randomized controlled trial

Indexed keywords

FOLIC ACID; IRON; TRACE ELEMENT;

ARTICLE; BIRTH WEIGHT; BODY HEIGHT; CHILD; CHILD GROWTH; CHILD HEALTH CARE; CHILD NUTRITION; CHINA; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FETUS OUTCOME; GROWTH CURVE; HUMAN; LONGITUDINAL STUDY; MALNUTRITION; MATERNAL NUTRITION; MOTHER CHILD RELATION; NEWBORN; PREGNANCY OUTCOME; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; RURAL AREA; THERAPY EFFECT;

ADULT; BODY HEIGHT; CHINA; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FOLIC ACID; FOLLOW-UP STUDIES; GROWTH; GROWTH DISORDERS; HUMANS; IRON; LONGITUDINAL STUDIES; MALE; MICRONUTRIENTS; ODDS RATIO; PREGNANCY; PREVALENCE; RISK FACTORS; THINNESS; WASTING SYNDROME; YOUNG ADULT;

EID: 84856668683     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2011.190     Document Type: Article

References (28)

1. Allen LH (2000). Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr 71 (Suppl), 1280S-1284S. (Pubitemid 30230529)
2. Christian P, Khatry SK, Katz J, Pradhan EK, LeClerq S, Shrestha SR et al. (2003). Effects of alternative maternal micronutrient supplements on low birth weight in rural Nepal: double blind randomised community trial. BMJ 326, 571-576.
3. de Onis M, Garza C, Onyango AW, Martorell R (eds) (2006). WHO child growth standards. Acta Paediatrics 95 (Suppl 450), S1-S101.
4. Filmer D, Pritchett L (2001). Estimating wealth effects without expenditure data-or tears: an application to educational enrollments in states of India. Demography 38, 115-132. (Pubitemid 33597463)
5. Huy ND, Le Hop T, Shrimpton R, Hoa CV (2009). An effectiveness trial of multiple micronutrient supplementation during pregnancy in Vietnam: impact on birthweight and on stunting in children at around 2 years of age. Food Nutr Bull 30 (4 Suppl), S506-S516.
6. Jiang T, Christian P, Khatry SK, Wu L, West KP (2005). Micronutrient deficiencies in early pregnancy are common, concurrent, and vary by season among rural Nepali pregnant women. J Nutr 135, 1106-1112. (Pubitemid 40638313)
7. Juarez-Vazquez J, Bonizzoni E, Scotti A (2002). Iron plus folate is more effective than iron alone in the treatment of iron deficiency anemia in pregnancy: a randomized, double blind clinical trial. BJOG 109, 1009-1014. (Pubitemid 35279131)
8. Kawai K, Spiegelman D, Shankar AH, Fawzi WW (2011). Maternal multiple micronutrient supplemen pregnancy outcomes in developing countrie and meta-regression. Bull World Health Organ 89, 402-411.
9. Kontic-Vucinic O, Sulovic N, Radunovic N (2006). Micronutrients in women's reproductive health: I. Vitamins. Int J Fertil Womens Med 51, 106-115.
10. Li Q, Yan H, Zeng L, Cheng Y, Liang W, Dang S et al. (2009). Effects of maternal multimicronutrient supplementation on the mental development of infants in rural western China: follow-up evaluation of a double-blind, randomised, controlled trial. Pediatrics 123, 685-692.
11. Lindblad B, Zaman S, Malik A, Martin H, Ekström AM, Amu S et al. (2005). Folate, vitamin B12, and homocysteine levels in South Asian women with growth-retarded fetuses. Acta Obstet Gynecol Scand 84, 1055-1061. (Pubitemid 41564528)
12. Lingxia Z, Hong Y, Xiong G, Shaonong D, Hong X (2003). Analysis on malnutrition of children under 3 years old in 40 poor counties in the western areas of China. Chin J Public Health 19, 55-58.
13. Ma A, Chen X, Wang Y, Xu R, Zheng M, Li J (2004). The multiple vitamin status of Chinese pregnant women with anemia and nonanemia in the last trimester. J Nutr Sci Vitaminol (Tokyo) 50, 87-92. (Pubitemid 38657516)
14. 12 deficiencies during pregnancy on fetal, infant, and child development. Food Nutr Bull 29 (2 Suppl), S101-S111.
15. Mu L, Lingxia Z, Jinping W, Lihua C, Yanming L, Haili L et al. (2005). Analysis of prevalence study on maternity and child care in the experimental units of new-type rural co-medical treatment of Shaanxi province. J Xi'an Jiaotong Univ Med Sci 26, 392-394.
16. Pathak P, Kapil U, Kapoor SK, Saxena R, Kumar A, Gupta N et al. (2004). Prevalence of multiple micronutrient deficiencies amongst pregnant women in a rural area of Haryana. Indian J Pediatr 71, 1007-1014. (Pubitemid 40036613)
17. Pathak P, Kapil U, Yajnik CS, Kapoor SK, Dwivedi SN, Singh R (2007). Iron, folate, and vitamin B12 stores among pregnant women in a rural area of Haryana State, India. Food Nutr Bull 28, 435-438. (Pubitemid 351149520)
18. Schümanna K, Ettle T, Szegner B, Elsenhans B, Solomons NW (2007). On risks and benefits of iron supplementation recommendations for iron intake revisited. J Trace Elements Med Biol 21, 147-168. (Pubitemid 47241218)
19. Seshadri S (2001). Prevalence of micronutrient deficiency particularly of iron, zinc and folic acid in pregnant women in South East Asia. Br J Nutr 85 (Suppl 2), S87-S92. (Pubitemid 32590773)
20. Stewart CP, Christian P, Le Clerq SC, West KP, Khatry SK (2009a). Antenatal supplementation with folic acid θ iron θ zinc improves linear growth and reduces peripheral adiposity in school-age children in rural Nepal. Am J Clin Nutr 90, 132-140.
21. Stewart CP, Christian P, Schulze KJ, Le Clerq SC, West KP, Khatry SK (2009b). Antenatal micronutrient supplementation reduces metabolic syndrome in 6-to 8-year-old children in rural Nepal. J Nutr 139, 1575-1581.
22. UNICEF/UNU/WHO (1999). Composition of a Multi-Micronutrient Supplement to be Used in Pilot Programmes Among Pregnant Women in Developing Countries. UNICEF: New York, NY.
23. Vaidya A, Saville N, Shrestha BP, Costello AM, Manandhar DS, Osrin D (2008). Effects of antenatal multiple micronutrient supplementation on children's weight and size at 2 years of age in Nepal: follow-up of a double-blind randomised controlled trial. Lancet 371, 492-499. (Pubitemid 351199865)
24. Villamor E, Saathoff E, Bosch RJ, Hertzmark E, Baylin A, Manji K et al. (2005). Vitamin supplementation of HIV-infected women improves postnatal child growth. Am J Clin Nutr 81, 880-888. (Pubitemid 41724998)
25. WHO (1995). Physical Status: The Use and Interpretation of Anthropometry. Expert Committee Report. WHO Technical Report Series No. 854. World Health Organization: Geneva (http://whqlibdoc.who.int/trs/WHO-TRS-854.pdf).
26. WHO (2006). Anthro 2005 for mobile devices version 1.00 Sfaga-dotwscGW (http://www.who.int/childgrowth/software/en/).
27. Zeng L, Cheng Y, Dang S, Yan H, Dibley M, Chang S et al. (2008). Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial. BMJ 337, a2001-a2011.
28. Zeng F, Song YY, Li Z (2006). A research on relationship between fetal growth restriction and vitamin nutritional status in late pregnancy. Chin J Matern Child Health Res 17, 4-5.