Antenatal supplementation with folic acid + iron + zinc improves linear growth and reduces peripheral adiposity in school-age children in rural Nepal

American Journal of Clinical Nutrition

Volumn 90, Issue 1, 2009, Pages 132-140

  Stewart, Christine P ^a   Christian, Parul ^a   LeClerq, Steven C ^a,b   West Jr , Keith P ^a   Khatry, Subarna K ^b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Nepal Nutrition Intervention Project Sarlahi   (Nepal)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; COPPER; CYANOCOBALAMIN; FERROUS FUMARATE; FOLIC ACID; MAGNESIUM; NICOTINIC ACID; PYRIDOXINE; RETINOL; RETINOL PALMITATE; RIBOFLAVIN; THIAMINE; VITAMIN D; VITAMIN K GROUP; ZINC SULFATE; IRON; ZINC;

ADIPOSE TISSUE; ANTHROPOMETRY; ARM CIRCUMFERENCE; ARM MUSCLE; ARTICLE; BODY COMPOSITION; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHILD; CHILD GROWTH; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; FETUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL NUTRITION; NEPAL; OBESITY; PRESCHOOL CHILD; RURAL AREA; SCAPULA; SCHOOL CHILD; SKINFOLD THICKNESS; STANDARD; TRICEPS BRACHII MUSCLE; WAIST CIRCUMFERENCE; WORLD HEALTH ORGANIZATION; BODY SIZE; DRUG EFFECT; EMBRYO DEVELOPMENT; GROWTH; HISTOLOGY; LOW BIRTH WEIGHT; NEWBORN; PHYSIOLOGY; PREGNANCY;

ADIPOSE TISSUE; BODY MASS INDEX; BODY SIZE; CHILD; EMBRYONIC DEVELOPMENT; FEMALE; FOLIC ACID; GROWTH; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; IRON; NEPAL; PREGNANCY; PRENATAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ZINC;

EID: 67649846461     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2008.27368     Document Type: Article

References (38)

1. Black RE, Allen LH, Bhutta ZA, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 2008;371:243-260
2. de Onis M. Child growth and development. In: Semba RD, Bloem MW, eds. Nutrition and health in developing countries. Totowa, NJ: Humana Press, 2001:71-91.
3. Christian P, Khatry SK, Katz J, et al. Effects of alternative maternal micronutrient supplements on low birth weight in rural Nepal: double blind randomised community trial. BMJ 2003;326:571. (Pubitemid 36337582)
4. Osrin D, Vaidya A, Shrestha Y, et al. Effects of antenatal multiple micronutrient supplementation on birthweight and gestational duration in Nepal: double-blind, randomised controlled trial. Lancet 2005;365:955-962 (Pubitemid 41071429)
5. Ramakrishnan U, Gonzalez-Cossio T, Neufeld LM, Rivera J, Martorell R. Multiple micronutrient supplementation during pregnancy does not lead to greater infant birth size than does iron-only supplementation: a randomized controlled trial in a semirural community in Mexico. Am J Clin Nutr 2003;77:720-725 (Pubitemid 36258586)
6. Friis H, Gomo E, Nyazema N, et al. Effect of multimicronutrient supplementation on gestational length and birth size: a randomized, placebo-controlled, double-blind effectiveness trial in Zimbabwe. Am J Clin Nutr 2004;80:178-184 (Pubitemid 41115572)
7. Kaestel P, Michaelsen KF, Aaby P, Friis H. Effects of prenatal multimicronutrient supplements on birth weight and perinatal mortality: a randomised, controlled trial in Guinea-Bissau. Eur J Clin Nutr 2005;59:1081-1089 (Pubitemid 43118170)
8. Supplementation with Multiple Micronutrients Intervention Trial (SUMMIT) Study Group, Shankar AH, Jahari AB, et al. Effect of maternal multiple micronutrient supplementation on fetal loss and infant death in Indonesia: a double-blind cluster-randomised trial. Lancet 2008;371:215-227
9. Fawzi WW, Msamanga GI, Urassa W, et al. Vitamins and perinatal outcomes among HIV-negative women in Tanzania. N Engl J Med 2007;356:1423-1431 (Pubitemid 46556327)
10. Gupta P, Ray M, Dua T, Radhakrishnan G, Kumar R, Sachdev HP. Multimicronutrient supplementation for undernourished pregnant women and the birth size of their offspring: a double-blind, randomized, placebo-controlled trial. Arch Pediatr Adolesc Med 2007;161:58-64. (Pubitemid 46045464)
11. Zagre NM, Desplats G, Adou P, Mamadoultaibou A, Aguayo VM. Prenatal multiple micronutrient supplementation has greater impact on birthweight than supplementation with iron and folic acid: a cluster-randomized, double-blind, controlled programmatic study in rural Niger. Food Nutr Bull 2007;28:317-327 (Pubitemid 350055637)
12. Roberfroid D, Huybregts L, Lanou H, et al. Effects of maternal multiple micronutrient supplementation on fetal growth: a double-blind randomized controlled trial in rural Burkina Faso. Am J Clin Nutr 2008;88:1330-1340
13. Haider BA, Bhutta ZA. Multiple-micronutrient supplementation forwomen during pregnancy. Cochrane Database Syst Rev 2006;4:CD004905.
14. Vaidya A, Saville N, Shrestha BP, de L Costello AM, Manandhar DS, Osrin D. Effects of antenatal multiple micronutrient supplementation on children's weight and size at 2 years of age in Nepal: follow-up of a double-blind randomised controlled trial. Lancet 2008;371:492-499 (Pubitemid 351199865)
15. Iannotti LL, Zavaleta N, Leon Z, Shankar AH, Caulfield LE. Maternal zinc supplementation and growth in Peruvian infants. Am J Clin Nutr 2008;88:154-160 (Pubitemid 351988695)
16. Osendarp SJ, van Raaij JM, Darmstadt GL, Baqui AH, Hautvast JG, Fuchs GJ. Zinc supplementation during pregnancy and effects on growth and morbidity in low birthweight infants: a randomised placebo controlled trial. Lancet 2001;357:1080-1085 (Pubitemid 32322539)
17. Christian P, West KP, Khatry SK, et al. Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal. Am J Clin Nutr 2003;78:1194-1202 (Pubitemid 39663462)
18. Tielsch JM, Khatry SK, Stoltzfus RJ, et al. Effect of daily zinc supplementation on child mortality in southern Nepal: a community-based, cluster randomised, placebo-controlled trial. Lancet 2007;370:1230-1239 (Pubitemid 47503301)
19. Tielsch JM, Khatry SK, Stoltzfus RJ, et al. Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trial. Lancet 2006;367:144-152 (Pubitemid 43078584)
20. Gibson RS. Principles of nutritional assessment. 2nd ed. New York, NY: Oxford University Press, 2005.
21. WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards based on length/height, weight and age. Acta Paediatr Suppl 2006;450:76-85.
22. de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ 2007;85:660-667 (Pubitemid 47416716)
23. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 1986;42:121-130
24. Golub MS, Gershwin ME, Hurley LS, Saito WY, Hendrickx AG. Studies of marginal zinc deprivation in rhesus monkeys. IV. Growth of infants in the first year. Am J Clin Nutr 1984;40:1192-1202 (Pubitemid 15221080)
25. Brown KH, Peerson JM, Rivera J, Allen LH. Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials. Am J Clin Nutr 2002;75:1062-1071 (Pubitemid 34547537)
26. Castillo-Duran C, Weisstaub G. Zinc supplementation and growth of the fetus and low birth weight infant. J Nutr 2003;133:1494S-7S. (Pubitemid 36548734)
27. MacDonald RS. The role of zinc in growth and cell proliferation. J Nutr 2000;130:1500S-8S.
28. Matsui T, Yamaguchi M. Zinc modulation of insulin-like growth factor's effect in osteoblastic MC3T3-E1 cells. Peptides 1995;16:1063-1068
29. Christian P, Jiang T, Khatry SK, LeClerq SC, Shrestha SR, West KP Jr. Antenatal supplementation with micronutrients and biochemical indicators of status and subclinical infection in rural Nepal. Am J Clin Nutr 2006;83:788-794 (Pubitemid 44713141)
30. Lonnerdal B. Dietary factors influencing zinc absorption. J Nutr 2000;130:1378S-83S. (Pubitemid 30244133)
31. Kuzawa CW. Adipose tissue in human infancy and childhood: an evolutionary perspective. Am J Phys Anthropol 1998;(suppl 27):177-209. (Pubitemid 128457206)
32. Christian P, Darmstadt GL, Wu L, et al. The effect of maternal micronutrient supplementation on early neonatal morbidity in rural Nepal: a randomised, controlled, community trial. Arch Dis Child 2008;93:660-664
33. Yajnik CS. Obesity epidemic in India: intrauterine origins? Proc Nutr Soc 2004;63:387-396
34. Yajnik CS, Fall CH, Coyaji KJ, et al. Neonatal anthropometry: the thin-fat Indian baby. The Pune Maternal Nutrition Study. Int J Obes Relat Metab Disord 2003;27:173-180
35. Bavdekar A, Yajnik CS, Fall CH, et al. Insulin resistance syndrome in 8-year-old Indian children: small at birth, big at 8 years, or both? Diabetes 1999;48:2422-2429
36. Joglekar CV, Fall CH, Deshpande VU, et al. Newborn size, infant and childhood growth, and body composition and cardiovascular disease risk factors at the age of 6 years: the Pune Maternal Nutrition Study. Int J Obes (Lond) 2007;31:1534-1544
37. Stein AD, Thompson AM, Waters A. Childhood growth and chronic disease: evidence from countries undergoing the nutrition transition. Matern Child Nutr 2005;1:177-184 (Pubitemid 41702546)
38. Jiang T, Christian P, Khatry SK, Wu L, West KP Jr. Micronutrient deficiencies in early pregnancy are common, concurrent, and vary by season among rural Nepali pregnant women. J Nutr 2005;135:1106-1112 (Pubitemid 40638313)