Associations of periodontal microorganisms with salivary proteins and MMP-8 in gingival crevicular fluid

Journal of Clinical Periodontology

Volumn 39, Issue 3, 2012, Pages 256-263

  Yakob, Maha ^a   Kari, Kirsti ^b   Tervahartiala, Taina ^b   Sorsa, Timo ^b   Söder, Per Östen ^a   Meurman, Jukka H ^b   Söder, Birgitta ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

GCF; MMP 8; periodontal disease; periodontal microorganisms; salivary albumin; salivary total protein

Indexed keywords

ALBUMINOID; NEUTROPHIL COLLAGENASE; SALIVA PROTEIN;

ARTICLE; BACTEROIDES; CASE CONTROL STUDY; CHEMISTRY; CHI SQUARE DISTRIBUTION; COHORT ANALYSIS; ENZYME ACTIVATION; ENZYMOLOGY; FEMALE; GINGIVITIS; HUMAN; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; PERIODONTITIS; PHYSIOLOGY; SALIVA; SECRETION (PROCESS); SECRETION RATE; TREPONEMA DENTICOLA;

ALBUMINS; BACTEROIDES; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; COHORT STUDIES; ENZYME ACTIVATION; FEMALE; GINGIVAL CREVICULAR FLUID; HUMANS; MALE; MATRIX METALLOPROTEINASE 8; MIDDLE AGED; PERIODONTITIS; SALIVA; SALIVARY PROTEINS AND PEPTIDES; SECRETORY RATE; TREPONEMA DENTICOLA;

EID: 84856623860     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2011.01813.x     Document Type: Article

References (62)

1. Aas, J. A., Paster, B. J., Stokes, L. N., Olsen, I., &, Dewhirst, F. E., (2005) Defining the normal bacterial flora of the oral cavity. Journal of Clinical Microbiology 43, 5721-5732. (Pubitemid 41612354)
2. Abico, Y., Sato, T., Mayanagi, G., &, Takahashi, N., (2010) Profiling of subgingival plaque biofilm microflora from periodontally healthy subjects and from subjects with periodontitis using quantitative real-time PCR. Journal of Periodontal Research 45, 389-395.
3. Airila-Mansson, S., Soder, B., &, Klinge, B., (2005) Bone height changes in individuals with periodontal disease: a 17-year prospective longitudinal study. Journal of Clinical Periodontology 32, 822-827. (Pubitemid 40923060)
4. Buduneli, N., &, Kinane, D. F., (2011) Host-derived diagnostic markers related to soft tissue destruction and bone degradation in periodontitis. Journal of Clinical Periodontology 38 (Suppl. 1), 85-105.
5. Dawes, C., &, Ong, B. Y., (1973) Circadian rhythms in the flow rate and proportional contribution of parotid to whole saliva volume in man. Archives of Oral Biology 18, 1145-1153.
6. Eggert, F. M., Maenz, L., &, Tam, Y. C., (1987) Measuring the interaction of human secretory glycoproteins with oral bacteria. Journal of Dental Research 66, 610-612.
7. Greene, J. C., &, Vermillion, J. R., (1964) The simplified oral hygiene index. The Journal of American Dental Association 68, 7-13.
8. Gürsoy, U. K., Könönen, E., Pradhan-Palikhe, P., Tervahartiala, T., Pussinen, P. J., Suominen-Taipale, L., &, Sorsa, T., (2010) Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis. Journal of Clinical Periodontology 37, 487-493.
9. Güven, O., &, De Visscher, J. G., (1982) Salivary IgA in periodontal disease. Journal of Periodontology 53, 334-335. (Pubitemid 12014296)
10. Haffajee, A. D., &, Socransky, S. S., (2005) Microbiology of periodontal diseases: introduction. Periodontol 2000 38, 9-12. (Pubitemid 43034320)
11. Hanemaaijer, R., Sorsa, T., Konttinen, Y. T., Ding, Y., Sutinen, M., Visser, H., van Hinsbergh, V. W., Helaakoski, T., Kainulainen, T., Rönkä, H., Tschesche, H., &, Salo, T., (1997) Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline. Journal of Biological Chemistry 272, 31504-31509. (Pubitemid 28013291)
12. Hemmila, I., Dakubu, S., Mukkala, V., Siitari, H., &, Lovgren, T., (1984) Europium as a label in time-resolved immunofluorometric assays. Analytical Biochemistry 137, 335-343.
13. Henskens, Y. M. C., vandenKeijbus, P. A. M., Veerman, E. C. I., VanderWeijden, G. A., Timmerman, M. F., Snoek, C. M., VanderVelden, U., &, Amerongen, A. V. N., (1996) Protein composition of whole and parotid saliva in healthy and periodontitis subjects-determination of cystatins, albumin, amylase and IgA. Journal of Periodontal Research 31, 57-65.
14. Henskens, Y. M., van der Velden, U., Veerman, E. C., &, Nieuw Amerongen, A. V., (1993) Protein, albumin and cystatin concentrations in saliva of healthy subjects and of patients with gingivitis or periodontitis. Journal of Periodontal Research 28, 43-48.
15. Hernández, M., Gamonal, J., Tervahartiala, T., Mäntylä, P., Rivera, O., Dezerega, A., Dutzan, N., &, Sorsa, T., (2010) Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study. Journal of Periodontology 81, 1644-1652.
16. Hollmann, R., &, Van der Hoeven, H. J., (1999) Inability of intact cells of Treponema denticola to degrade human serum proteins IgA, IgG and albumin. Journal of Clinical Periodontology 26, 477-479.
17. Holt, S. C., &, Bramanti, T. E., (1991) Factors in virulence expression and their role in periodontal disease pathogenesis. Critical Reviews in Oral Biology and Medicine 2, 177-281.
18. Hugoson, A., &, Rolandsson, M., (2011) Periodontal disease in relation to smoking and the use of Swedish snus: epidemiological studies covering 20 years (1983-2003). Journal of Clinical Periodontology 38, 809-816.
19. Jenzano, J. W., Brown, C. K., &, Mauriello, S. M., (1987) Temporal variations of glandular kallikrein, protein and amylase in mixed human saliva. Archives of Oral Biology 32, 757-759.
20. Jin, L. J., Söder, P. O., Asman, B., &, Bergström, K., (1995) Granulocyte elastase in gingival crevicular fluid: improved monitoring of the site-specific response to treatment in patients with destructive periodontitis. Journal of Clinical Periodontology 22, 240-246.
21. Kaufman, E., &, Lamster, I. B., (2000) Analysis of saliva for periodontal diagnosis-a review. Journal of Clinical Periodontology 27, 453-465.
22. Kornman, K. S., Page, R. C., &, Tonetti, M. S., (1997) The host response to the microbial challenge in periodontitis: assembling the players. Periodontology 2000 14, 33-53. (Pubitemid 127601170)
23. Kumar, P. S., Griffen, A. L., Barton, J. A., Paster, B. J., Moeschberger, M. L., &, Leys, E. J., (2003) New bacterial species associated with chronic periodontitis. Journal of Dental Research 82, 338-344. (Pubitemid 41756823)
24. Lee, W., Aitken, S., Sodek, J., &, McCulloch, C. A., (1995) Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: role of active enzyme in human periodontitis. Journal of Periodontal Research 30, 23-33.
25. Lehtonen, O. P., Grahn, E. M., Stahlberg, T. H., &, Laitinen, L. A., (1984) Amount and avidity of salivary and serum antibodies against streptococcus-mutans in 2 groups of human- subjects with different dental-caries susceptibility. Infection and Immunity 43, 308-313. (Pubitemid 14218733)
26. Leppilahti, J. M., Ahonen, M. M., Hernández, M., Munjal, S., Netuschil, L., Uitto, V. J., Sorsa, T., &, Mäntylä, P., (2011) Oral rinse MMP-8 point-of-care immuno test identifies patients with strong periodontal inflammatory burden. Oral Diseases 17, 115-122.
27. Löe, H., &, Silness, J., (1963) Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontologica Scandinavia 21, 533-551.
28. Lowry, O. H., Rosebrough, N. J., Farr, A. L., &, Randall, R. J., (1951) Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193, 265-275.
29. Mäkinen, K. K., &, Mäkinen, P. L., (1996) The peptidolytic capacity of the spirochete system. Medical Microbiololgy and Immunology 185, 1-10.
30. Mancini, S., Romanelli, R., Laschinger, C. A., Overall, C. M., Sodek, J., &, McCulloch, C. A., (1999) Assessment of a novel screening test for neutrophil collagenase activity in the diagnosis of periodontal diseases. Journal of Periodontology 70, 1292-1302.
31. Mandel, I. D., &, Khurana, H. S., (1969) The relation of human salivary gamma A globulin and albumin to flow rate. Archives of Oral Biology 14, 1433-1435.
32. Mäntylä, P., Stenman, M., Kinane, D. F., Tikanoja, S., Luoto, H., Salo, T., &, Sorsa, T., (2003) Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis. Journal of Periodontal Research 38, 436-439. (Pubitemid 37465553)
33. Mäntylä, P., Stenman, M., Kinane, D., Salo, T., Suomalainen, K., Tikanoja, S., &, Sorsa, T., (2006) Monitoring periodontal disease status in smokers and nonsmokers using a gingival crevicular fluid matrix metalloproteinase-8-specific chair-side test. Journal of Periodontal Research 41, 503-512. (Pubitemid 44656925)
34. McGurk, M., Hanford, L., Justice, S., &, Metcalfe, R. A., (1990) The secretory characteristics of epidermal growth factor in human saliva. Archives of Oral Biology 35, 653-659.
35. Meurman, J. H., Wahlfors, J., Korhonen, A., Alakuijala, P., Vaisanen, P., Torkko, H., &, Janne, J., (1997) Identification of Bacteroides forsythus in subgingival dental plaque with the aid of a rapid PCR method. Journal of Dental Research 76, 1376-1380. (Pubitemid 127732220)
36. Offenbacher, S., Barros, S. P., &, Beck, J. D., (2008) Rethinking periodontal inflammation. Journal of Periodontology 79, 1577-1584.
37. Oppenheim, F. G., (1970) Preliminary observations on the presence and origin of serum albumin in human saliva. Helvetica Odontologica Acta 14, 10-17.
38. Ramseier, C. A., Kinney, J. S., Herr, A. E., Braun, T., Sugai, J. V., Shelburne, C. A., Rayburn, L. A., Tran, H. M., Singh, A. K., &, Giannobile, W. V., (2009) Identification of pathogen and host-response markers correlated with periodontal disease. Journal of Periodontology 80, 436-446.
39. Rantonen, P. J., &, Meurman, J. H., (2000) Correlations between total protein, lysozyme, immunoglobulins, amylase, and albumin in stimulated whole saliva during daytime. Acta Odontologica Scandinavia 58, 160-165.
40. Romanelli, R., Mancini, S., Laschinger, C., Overall, C. M., Sodek, J., &, McCulloch, C. A., (1999) Activation of neutrophil collagenase in periodontitis. Infection and Immunity 67, 2319-2326. (Pubitemid 29200488)
41. Salonen, J. I., &, Paunio, K. U., (1991) An intracrevicular washing method for collection of crevicular contents. Scandinavian Journal of Dental Research 99, 406-412.
42. Sanz, M., Lau, L., Herrera, D., Morillo, J. M., &, Silva, A., (2004) Methods of detection of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythensis in periodontal microbiology, with special emphasis on advanced molecular techniques: a review. Journal of Clinical Periodontology 31, 1034-1047. (Pubitemid 39643699)
43. Seemann, R., Hägewald, S. J., Sztankay, V., Drews, J., Bizhang, M., &, Kage, A., (2004) Levels of parotid and submandibular/sublingual salivary immunoglobulin A in response to experimental gingivitis in humans. Clinical Oral Investigations 8, 233-237.
44. Silness, J., &, Löe, H., (1964) Periodontal disease in pregnancy. Ii. Correlation between oral hygiene and periodontal condtion. Acta Odontologica Scandinavia 22, 121-135.
45. Socransky, S. S., &, Haffajee, A. D., (2005) Periodontal microbial ecology. Periodontololy 2000 38, 135-187. (Pubitemid 43034326)
46. Socransky, S. S., Haffajee, A. D., Cugini, M. A., Smith, C., &, Kent, R. L., (1998) Microbial complexes in subgingival plaque. Journal of Clinical Periodontology 25, 134-144. (Pubitemid 128705944)
47. Söder, B., Jin, L. J., Klinge, B., &, Söder, P. O., (2007a) Periodontitis and premature death: a 16-year longitudinal study in a Swedish urban population. Journal of Periodontal Research 42, 361-366.
48. Söder, B., Jin, L. J., &, Wickholm, S., (2002) Granulocyte elastase, matrix metalloproteinase-8 and prostaglandin E-2 in gingival crevicular fluid in matched clinical sites in smokers and non-smokers with persistent periodontitis. Journal of Clinical Periodontology 29, 384-391. (Pubitemid 41697824)
49. Söder, B., Mansson, S. A., Söder, P. O., Kari, K., &, Meurman, J., (2006) Levels of matrix metalloproteinases-8 and-9 with simultaneous presence of periodontal pathogens in gingival crevicular fluid as well as matrix metalloproteinase-9 and cholesterol in blood. Journal of Periodontal Research 41, 411-417. (Pubitemid 44337256)
50. Söder, B., Yakob, M., Nowak, J., &, Jogestrand, T., (2007b) Risk for the development of atherosclerosis in women with a high amount [corrected] of dental plaque and severe gingival inflammation. Internation Journal of Dental Hygiene 5, 133-138.
51. Söder, P. O., Jin, L. J., Söder, B., &, Wikner, S., (1994) Periodontal status in an urban adult population in Sweden. Community Dentistry and Oral Epidemiology 22, 106-111.
52. Söder, P. O., Söder, B., Nowak, J., &, Jogestrand, T., (2005) Early carotid atherosclerosis in subjects with periodontal diseases. Stroke 36, 1195-1200. (Pubitemid 40798738)
53. Sorsa, T., Hernández, M., Leppilahti, J., Munjal, S., Netuschil, L., &, Mäntylä, P., (2010) Detection of gingival crevicular fluid MMP-8 levels with different laboratory andchair-side methods. Oral Diseases 16, 39-45.
54. Sorsa, T., Ingman, T., Suomalainen, K., Haapasalo, M., Konttinen, Y. T., Lindy, O., Saari, H., &, Uitto, V. J., (1992) Identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases. Infection and Immunity 60, 4491-4495.
55. Sorsa, T., Tervahartiala, T., Leppilahti, J., Hernandez, M., Gamonal, J., Tuomainen, A. M., Lauhio, A., Pussinen, P. J., &, Mäntylä, P., (2011) Collagenase-2 (MMP-8) as a point-of-care biomarker in periodontitis and cardiovascular diseases. Therapeutic response to non-antimicrobial properties of tetracyclines. Pharmacological Research 63, 108-13.
56. Sorsa, T., Tjäderhane, L., Konttinen, Y. T., Lauhio, A., Salo, T., Lee, H. M., Golub, L. M., Brown, D. L., &, Mäntylä, P., (2006) Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Annals of Medicine 38, 306-321. (Pubitemid 44385100)
57. Sorsa, T., Tjäderhane, L., &, Salo, T., (2004) Matrix metalloproteinases (MMPs) in oral diseases. Oral Diseases 10, 311-318. (Pubitemid 39564343)
58. Takeuchi, Y., Umeda, M., Sakamoto, M., Benno, Y., Huang, Y., &, Ishikawa, I., (2001) Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction. Journal of Periodontology 72, 1354-1363. (Pubitemid 32998712)
59. Uitto, V. J., Overall, C. M., &, McCulloch, C., (2003) Proteolytic host cell enzymes in gingival crevice fluid. Periodontology 2000 31, 77-104. (Pubitemid 37487411)
60. Uzel, N. G., Teles, F. R., Teles, R. P., Song, X. Q., Torresyap, G., Socransky, S. S., &, Haffajee, A. D., (2011) Microbial shifts during dental biofilm re-development in the absence of oral hygiene in periodontal health and disease. Journal of Clinical Periodontology 38, 612-620.
61. Wade, W. G., (2011) Has the use of molecular methods for the characterization of the human oral microbiome changed our understanding of the role of bacteria in the pathogenesis of periodontal disease? Journal of Clinical Periodontology 38 (Suppl. 1), 7-16.
62. Wahlfors, J., Meurman, J. H., Vaisanen, P., Alakuijala, P., Korhonen, A., Torkko, H., &, Janne, J., (1995) Simultaneous detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis by a rapid PCR method. Journal of Dental Research 74, 1796-1801.