Functional analysis of Pro-inflammatory properties within the cerebrospinal fluid after subarachnoid hemorrhage in vivo and in vitro

Journal of Neuroinflammation

Volumn 9, Issue , 2012, Pages

  Schneider, Ulf C ^a   Schiffler, Jennifer ^a   Hakiy, Nahid ^a   Horn, Peter ^a   Vajkoczy, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cerebral vasospasm; Delayed brain injury; Neuro inflammation; Secondary brain injury; Subarachnoid hemorrhage

Indexed keywords

FLUORESCENT DYE;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; BRAIN EDEMA; BRAIN INJURY; BRAIN VASOSPASM; CELL ASSAY; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; ENDOTHELIUM; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACRANIAL HYPERTENSION; INTRAVITAL MULTIFLUORESCENCE IMAGING; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LEUKOCYTE COUNT; LEUKOCYTE ROLLING; MALE; MICROCIRCULATION; MICROVASCULATURE; MONOCYTE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PERFUSION AND SUPERFUSION; QUANTITATIVE ANALYSIS; SKINFOLD; SUBARACHNOID HEMORRHAGE; SUBARACHNOID SPACE; SURGICAL DRAINAGE; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; CELL MOTION; CEREBROSPINAL FLUID; DIGITAL SUBTRACTION ANGIOGRAPHY; DISEASE MODEL; ECHOGRAPHY; ENDOTHELIUM CELL; FEMALE; INFLAMMATION; LEUKOCYTE; METABOLISM; METHODOLOGY; MIDDLE AGED; MIDDLE CEREBRAL ARTERY; PATHOLOGY; PHYSIOLOGY; TIME;

ADULT; AGED; ANGIOGRAPHY, DIGITAL SUBTRACTION; ANIMALS; BRAIN EDEMA; CELL MOVEMENT; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTES; MALE; MICE; MIDDLE AGED; MIDDLE CEREBRAL ARTERY; MONOCYTES; SUBARACHNOID HEMORRHAGE; TIME FACTORS; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VASOSPASM, INTRACRANIAL;

EID: 84856611258     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-28     Document Type: Article

References (27)

1. Barth M, Capelle H-H, Weidauer S, Weiss C, Münch E, Thomé C, Luecke T, Schmiedek P, Kasuya H, Vajkoczy P. Effect of nicardipine prolonged-release implants on cerebral vasospasm and clinical outcome after severe aneurysmal subarachnoid hemorrhage: a prospective, randomized, double-blind phase IIa study. Stroke 2007, 38:330-336. 10.1161/01.STR.0000254601.74596.0f, 17185636.
2. Vajkoczy P, Meyer B, Weidauer S, Raabe A, Thomé C, Ringel F, Breu V, Schmiedek P. Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter phase IIa study. J Neurosurg 2005, 103:9-17. 10.3171/jns.2005.103.1.0009, 16121967.
3. Hansen-Schwartz J, Vajkoczy P, Macdonald RL, Pluta RM, Zhang JH. Cerebral vasospasm: looking beyond vasoconstriction. Trends Pharmacol Sci 2007, 28:252-256. 10.1016/j.tips.2007.04.002, 17466386.
4. Osuka K, Suzuki Y, Tanazawa T, Hattori K, Yamamoto N, Takayasu M, Shibuya M, Yoshida J. Interleukin-6 and development of vasospasm after subarachnoid haemorrhage. Acta Neurochir (Wien) 1998, 140:943-951.
5. Polin RS, Bavbek M, Shaffrey ME, Billups K, Bogaev CA, Kassell NF, Lee KS. Detection of soluble E-selectin, ICAM-1, VCAM-1, and L-selectin in the cerebrospinal fluid of patients after subarachnoid hemorrhage. J Neurosurg 1998, 89:559-567. 10.3171/jns.1998.89.4.0559, 9761049.
6. Hagen AA, Gerber JN, Sweeley CC, White RP, Robertson JT. Levels and disappearance of prostaglandin F2a in cerebral spinal fluid: a clinical and experimental study. Stroke 1977, 8:672-675. 10.1161/01.STR.8.6.672, 929655.
7. Boullin DJ, Bunting S, Blaso WP, Hunt TM, Moncada S. Responses of human and baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: their relevance to cerebral arterial spasm in man. Br J Clin Pharmacol 1979, 7:139-147. 1429425, 367413.
8. Brandt L, Ljunggren B, Andersson KE, Hindfelt B, Uski T. Prostaglandin metabolism and prostacyclin in cerebral vasospasm. Gen Pharmac 1982, 14:141-143.
9. Rodriguez-y-Baena R, Gaetani P, Folco G, Vigano T, Paoletti P. Arachidonate metabolites and vasospasm after subarachnoid hemorrhage. Neurol Res 1986, 8:25-32.
10. Rodriguez-y-Baena R, Gaetani P, Grignani G, Pacchiarini L. Effect of nimodipine on arachidonic acid metabolites after subarachnoid hemorrhage. Acta Neurol Scand 1987, 76:267-271. 10.1111/j.1600-0404.1987.tb03579.x, 3120489.
11. Paoletti P, Gaetani P, Grignain G, Pacchiarini L, Silvani V, Rodriguez-y-Baena R. CSF leukotriene C4 following subarachnoid hemorrhage. J Neurosurg 1988, 69:488-493. 10.3171/jns.1988.69.4.0488, 3418380.
12. Rodriguez-y-Baena R, Gaetani P, Paoletti P. A study on cisternal CSF levels of arachidonic acid metabolites after aneurysmal subarachnoid hemorrhage. J Neurol Sci 1988, 84:329-335. 10.1016/0022-510X(88)90136-0, 3132538.
13. Chehrazi BB, Giri S, Joy RM. Prostaglandins and vasoactive amins in cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke 1989, 20:217-224. 10.1161/01.STR.20.2.217, 2465585.
14. Minami N, Tani E, Yokota Y, Maeda Y, Yamaura I. Immunohistochemistry of leukotriene C4 in experimental cerebral vasospasm. Acta Neuropathol 1991, 81:401-407. 10.1007/BF00293461, 2028744.
15. Pradilla G, Chaichana KL, Hoang S, Huang J, Tamargo RJ. Inflammation and cerebral vasospasm after subarachnoid hemorrhage. Neurosurg Clin N Am 2010, 21:365-379. 10.1016/j.nec.2009.10.008, 20380976.
16. Vajkoczy P, Menger MD, Simpson E, Messmer K. Angiogenesis and vascularization of murine pancreatic islet isografts. Transplantation 1995, 60:123-127.
17. Laird AD, Vajkoczy P, Shawver LK, Thurnher A, Liang C, Mohammadi M, Schlessinger J, Ullrich A, Hubbard SR, Blake RA, Fong TA, Strawn LM, Sun L, Tang C, Hawtin R, Tang F, Shenoy N, Hirth KP, McMahon G, Cherrington. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 2000, 60:4152-4160.
18. Laschke MW, Elitzsch A, Vollmar B, Vajkoczy P, Menger MD. Combined inhibition of vascular endothelial growth factor (VEGF), fibroblast growth factor and platelet-derived growth factor, but not inhibition of VEGF alone, effectively suppresses angiogenesis and vessel maturation in endometriotic lesions. Hum Reprod 2006, 21:262-268.
19. Fiedler U, Reiss Y, Scharpfenecker M, Grunow V, Koidl S, Thurston G, Gale NW, Witzenrath M, Rosseau S, Suttorp N, Sobke A, Herrmann M, Preissner KT, Vajkoczy P, Augustin HG. Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Nat Med 2006, 12:235-239. 10.1038/nm1351, 16462802.
20. Choi EY, Chavakis E, Czabanka MA, Langer HF, Fraemohs L, Economopoulou M, Kundu RK, Orlandi A, Zheng YY, Prieto DA, Ballantyne CM, Constant SL, Aird WC, Papayannopoulou T, Gahmberg CG, Udey MC, Vajkoczy P, Quertermous T, Dimmeler S, Weber C, Chavakis T. Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment. Science 2008, 322:1101-1104. 10.1126/science.1165218, 2753175, 19008446.
21. Rasi K, Piuhola J, Czabanka M, Sormunen R, Ilves M, Leskinen H, Rysä J, Kerkelä R, Janmey P, Heljasvaara R, Peuhkurinen K, Vuolteenaho O, Ruskoaho H, Vajkoczy P, Pihlajaniemi T, Eklund L. Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy. Circ Res 2010, 107:1241-1252. 10.1161/CIRCRESAHA.110.222133, 20847313.
22. Ostrowski RP, Colohan AR, Zhang JH. Molecular mechanisms of early brain injury after subarachnoid hemorrhage. Neurol Res 2006, 28:399-414. 10.1179/016164106X115008, 16759443.
23. Tulamo R, Frösen J, Junnikkala S, Paetau A, Pitkäniemi J, Kangasniemi M, Niemelä M, Jääskeläinen J, Jokitalo E, Karatas A, Hernesniemi J, Meri S. Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture. Neurosurgery 2006, 59:1069-1076. discussion 1076-7.
24. Frösen J, Piippo A, Paetau A, Kangasniemi M, Niemelä M, Hernesniemi J, Jääskeläinen J. Remodeling of saccular cerebral artery aneurysm wall is associated with rupture: histological analysis of 24 unruptured and 42 ruptured cases. Stroke 2004, 35:2287-2293. 10.1161/01.STR.0000140636.30204.da, 15322297.
25. Kataoka K, Taneda M, Asai T, Kinoshita A, Ito M, Kuroda R. Structural fragility and inflammatory response of ruptured cerebral aneurysms. A comparative study between ruptured and unruptured cerebral aneurysms. Stroke 1999, 30:1396-1401. 10.1161/01.STR.30.7.1396, 10390313.
26. Sarrafzadeh A, Schlenk F, Gericke C, Vajkoczy P. Relevance of cerebral interleukin-6 after aneurysmal subarachnoid hemorrhage. Neurocrit Care 2010, 13:339-346. 10.1007/s12028-010-9432-4, 20725805.
27. Fassbender K, Hodapp B, Rossol S, Bertsch T, Schmeck J, Schütt S, Fritzinger M, Horn P, Vajkoczy P, Wendel-Wellner M, Ragoschke A, Kuehl S, Brunner J, Schürer L, Schmiedeck P, Hennerici M. Endothelin-1 in subarachnoid hemorrhage: an acute-phase reactant produced by cerebrospinal fluid leukocytes. Stroke 2000, 31:2971-2975. 10.1161/01.STR.31.12.2971, 11108758.