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Volumn 119, Issue 5, 2012, Pages 1190-1199

The cell cycle regulator CDC25A is a target for JAK2V617F oncogene

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; INITIATION FACTOR 2ALPHA; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE CDC25A; STAT5 PROTEIN; UNCLASSIFIED DRUG;

EID: 84856599979     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-01-327742     Document Type: Article
Times cited : (26)

References (35)
  • 5
    • 77951759127 scopus 로고    scopus 로고
    • Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease
    • Akada H, Yan D, Zou H, Fiering S, Hutchison RE, Mohi MG. Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease. Blood. 2010;115(17):3589-3597.
    • (2010) Blood. , vol.115 , Issue.17 , pp. 3589-3597
    • Akada, H.1    Yan, D.2    Zou, H.3    Fiering, S.4    Hutchison, R.E.5    Mohi, M.G.6
  • 6
    • 77956280929 scopus 로고    scopus 로고
    • Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knockin mice
    • Marty C, Lacout C, Martin A, et al. Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knockin mice. Blood. 2010;116(5):783-787.
    • (2010) Blood , vol.116 , Issue.5 , pp. 783-787
    • Marty, C.1    Lacout, C.2    Martin, A.3
  • 8
    • 33750038853 scopus 로고    scopus 로고
    • Oncogenic kinases of myeloproliferative disorders induce both protein synthesis and G1 activators [3]
    • DOI 10.1038/sj.leu.2404361, PII 2404361
    • Lelièvre H, Cervera N, Finetti P, et al. Oncogenic kinases of myeloproliferative disorders induce both protein synthesis and G1 activators. Leukemia. 2006;20(10):1885-1888. (Pubitemid 44575001)
    • (2006) Leukemia , vol.20 , Issue.10 , pp. 1885-1888
    • Lelievre, H.1    Cervera, N.2    Finetti, P.3    Delhommeau, F.4    Vainchenker, W.5    Bertucci, F.6    Birnbaum, D.7
  • 9
    • 34250865564 scopus 로고    scopus 로고
    • CDC25 phosphatases in cancer cells: Key players? Good targets?
    • DOI 10.1038/nrc2169, PII NRC2169
    • Boutros R, Lobjois V, Ducommun B. CDC25 phosphatases in cancer cells: key players? Good targets? Nat Rev Cancer. 2007;7(7):495-507. (Pubitemid 46985396)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.7 , pp. 495-507
    • Boutros, R.1    Lobjois, V.2    Ducommun, B.3
  • 10
    • 0033000779 scopus 로고    scopus 로고
    • Serum-induced expression of the cdc25A gene by relief of E2F-mediated repression
    • Chen X, Prywes R. Serum-induced expression of the cdc25A gene by relief of E2F-mediated repression. Mol Cell Biol. 1999;19(7):4695-4702. (Pubitemid 29289507)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.7 , pp. 4695-4702
    • Chen, X.1    Prywes, R.2
  • 11
    • 0034014307 scopus 로고    scopus 로고
    • 1/S-promoting mechanism parallel to the pRb/E2F pathway
    • DOI 10.1128/MCB.20.10.3497-3509.2000
    • Santoni-Rugiu E, Falck J, Mailand N, Bartek J, Lukas J. Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway. Mol Cell Biol. 2000;20(10):3497-3509. (Pubitemid 30243895)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.10 , pp. 3497-3509
    • Santoni-Rugiu, E.1    Falck, J.2    Mailand, N.3    Bartek, J.4    Lukas, J.5
  • 12
    • 18144388986 scopus 로고    scopus 로고
    • The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter
    • Barr é B, Vigneron A, Coqueret O. The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter. J Biol Chem. 2005;280(16):15673-15681.
    • (2005) J Biol Chem , vol.280 , Issue.16 , pp. 15673-15681
    • Barré, B.1    Vigneron, A.2    Coqueret, O.3
  • 13
    • 1842486794 scopus 로고    scopus 로고
    • Cdc25A phosphatase: Combinatorial phosphorylation, ubiquitylation and proteolysis
    • DOI 10.1038/sj.onc.1207394
    • Busino L, Chiesa M, Draetta GF, Donzelli M. Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysis. Oncogene. 2004;23(11):2050-2056. (Pubitemid 38496734)
    • (2004) Oncogene , vol.23 , Issue.11 REV. ISS. 1 , pp. 2050-2056
    • Busino, L.1    Chiesa, M.2    Draetta, G.F.3    Donzelli, M.4
  • 15
    • 37349094929 scopus 로고    scopus 로고
    • GSK-3beta Targets Cdc25A for Ubiquitin-Mediated Proteolysis, and GSK-3beta Inactivation Correlates with Cdc25A Overproduction in Human Cancers
    • DOI 10.1016/j.ccr.2007.12.002, PII S1535610807003716
    • Kang T, Wei Y, Honaker Y, et al. GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Cancer Cell. 2008;13(1):36-47. (Pubitemid 350309739)
    • (2008) Cancer Cell , vol.13 , Issue.1 , pp. 36-47
    • Kang, T.1    Wei, Y.2    Honaker, Y.3    Yamaguchi, H.4    Appella, E.5    Hung, M.-C.6    Piwnica-Worms, H.7
  • 16
    • 77950517895 scopus 로고    scopus 로고
    • Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A
    • Pereg Y, Liu BY, O'Rourke KM, et al. Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A. Nat Cell Biol. 2010;12(4):400-406.
    • (2010) Nat Cell Biol , vol.12 , Issue.4 , pp. 400-406
    • Pereg, Y.1    Liu, B.Y.2    O'Rourke, K.M.3
  • 17
    • 33847013064 scopus 로고    scopus 로고
    • Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability
    • Ray D, Terao Y, Fuhrken PG, et al. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Res. 2007;67(3):984-991.
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 984-991
    • Ray, D.1    Terao, Y.2    Fuhrken, P.G.3
  • 20
    • 65949109269 scopus 로고    scopus 로고
    • Upregulation of the CDC25A phosphatase down-stream of the NPM/ALK oncogene participates to anaplastic large cell lymphoma enhanced proliferation
    • Fernandez-Vidal A, Mazars A, Gautier EF, Prevost G, Payrastre B, Manenti S. Upregulation of the CDC25A phosphatase down-stream of the NPM/ALK oncogene participates to anaplastic large cell lymphoma enhanced proliferation. Cell Cycle. 2009;8(9):1373-1379.
    • (2009) Cell Cycle , vol.8 , Issue.9 , pp. 1373-1379
    • Fernandez-Vidal, A.1    Mazars, A.2    Gautier, E.F.3    Prevost, G.4    Payrastre, B.5    Manenti, S.6
  • 21
    • 60549098655 scopus 로고    scopus 로고
    • IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells
    • Brezak MC, Valette A, Quaranta M, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009;124(6):1449-1456.
    • (2009) Int J Cancer , vol.124 , Issue.6 , pp. 1449-1456
    • Brezak, M.C.1    Valette, A.2    Quaranta, M.3
  • 22
    • 77649085550 scopus 로고    scopus 로고
    • Inhibitors of Cdc25 phosphatases as anticancer agents: A patent review
    • Lavecchia A, Di Giovanni C, Novellino E. Inhibitors of Cdc25 phosphatases as anticancer agents: a patent review. Expert Opin Ther Pat. 2010;20(3):405-425.
    • (2010) Expert Opin Ther Pat , vol.20 , Issue.3 , pp. 405-425
    • Lavecchia, A.1    Di Giovanni, C.2    Novellino, E.3
  • 23
    • 33645400695 scopus 로고    scopus 로고
    • X-inactivation-based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative ET and MMM patients with clonal hematopoiesis
    • DOI 10.1182/blood-2005-09-3900
    • Levine RL, Belisle C, Wadleigh M, et al. X-inactivation-based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative ET and MMM patients with clonal hematopoiesis. Blood. 2006;107(10):4139-4141. (Pubitemid 43726824)
    • (2006) Blood , vol.107 , Issue.10 , pp. 4139-4141
    • Levine, R.L.1    Belisle, C.2    Wadleigh, M.3    Zahrieh, D.4    Lee, S.5    Chagnon, P.6    Gilliland, D.G.7    Busque, L.8
  • 24
    • 49449094277 scopus 로고    scopus 로고
    • New mutations of MPL in primitive myelofibrosis: Only the MPL W515 mutations promote a G1/S-phase transition
    • Chaligné R, Tonetti C, Besancenot R, et al. New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition. Leukemia. 2008;22(8):1557-1566.
    • (2008) Leukemia , vol.22 , Issue.8 , pp. 1557-1566
    • Chaligné, R.1    Tonetti, C.2    Besancenot, R.3
  • 25
    • 0344393475 scopus 로고    scopus 로고
    • Distinct modes of deregulation of the proto-oncogenic Cdc25A phosphatase in human breast cancer cell lines
    • DOI 10.1038/sj.onc.1206976
    • Löffler H, Syljuasen RG, Bartkova J, Worm J, Lukas J, Bartek J. Distinct modes of deregulation of the proto-oncogenic Cdc25A phosphatase in human breast cancer cell lines. Oncogene. 2003;22(50):8063-8071. (Pubitemid 37487297)
    • (2003) Oncogene , vol.22 , Issue.50 , pp. 8063-8071
    • Loffler, H.1    Syljuasen, R.G.2    Bartkova, J.3    Worm, J.4    Lukas, J.5    Bartek, J.6
  • 26
    • 5044229348 scopus 로고    scopus 로고
    • Molecular mechanisms of translational control
    • DOI 10.1038/nrm1488
    • Gebauer F, Hentze MW. Molecular mechanisms of translational control. Nat Rev Mol Cell Biol. 2004;5(10):827-835. (Pubitemid 39336276)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.10 , pp. 827-835
    • Gebauer, F.1    Hentze, M.W.2
  • 27
    • 54749089211 scopus 로고    scopus 로고
    • Multimodal control of Cdc25A by nitrosative stress
    • Tomko RJ Jr, Lazo JS. Multimodal control of Cdc25A by nitrosative stress. Cancer Res. 2008;68(18):7457-7465.
    • (2008) Cancer Res , vol.68 , Issue.18 , pp. 7457-7465
    • Tomko Jr., R.J.1    Lazo, J.S.2
  • 29
    • 77952786601 scopus 로고    scopus 로고
    • EIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress
    • Bevilacqua E, Wang X, Majumder M, et al. eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress. J Biol Chem. 2010;285(22):17098-17111.
    • (2010) J Biol Chem , vol.285 , Issue.22 , pp. 17098-17111
    • Bevilacqua, E.1    Wang, X.2    Majumder, M.3
  • 31
    • 0032546266 scopus 로고    scopus 로고
    • Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: Protection is correlated with up regulation of Bcl-X(L)
    • Amarante-Mendes GP, McGahon AJ, Nishioka WK, Afar DE, Witte ON, Green DR. Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL. Oncogene. 1998;16(11):1383-1390. (Pubitemid 28151845)
    • (1998) Oncogene , vol.16 , Issue.11 , pp. 1383-1390
    • Amarante-Mendes, G.P.1    McGahon, A.J.2    Nishioka, W.K.3    Afar, D.E.H.4    Witte, O.N.5    Green, D.R.6
  • 33
    • 67349223963 scopus 로고    scopus 로고
    • P27 deregulation by Skp2 overexpression induced by the JAK2V617 mutation
    • Furuhata A, Kimura A, Shide K, et al. p27 deregulation by Skp2 overexpression induced by the JAK2V617 mutation. Biochem Biophys Res Commun. 2009;383(4):411-416.
    • (2009) Biochem Biophys Res Commun , vol.383 , Issue.4 , pp. 411-416
    • Furuhata, A.1    Kimura, A.2    Shide, K.3
  • 35
    • 77949904181 scopus 로고    scopus 로고
    • Recent developments on JAK2 inhibitors: A patent review
    • Kiss R, Sayeski PP, Keseru GM. Recent developments on JAK2 inhibitors: a patent review. Expert Opin Ther Pat. 2010;20(4):471-495.
    • (2010) Expert Opin Ther Pat , vol.20 , Issue.4 , pp. 471-495
    • Kiss, R.1    Sayeski, P.P.2    Keseru, G.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.