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Volumn 9, Issue 2, 2012, Pages 74-76

Melanoma in 2011: A new paradigm tumor for drug development

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; B RAF KINASE; B RAF KINASE INHIBITOR; DACARBAZINE; IMATINIB; IPILIMUMAB; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PEGINTERFERON ALPHA2B; STEM CELL FACTOR; VEMURAFENIB;

EID: 84856598992     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2011.201     Document Type: Review
Times cited : (23)

References (10)
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    • Flaherty, K.T.1
  • 2
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman, P. B. et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364, 2507-2516 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2507-2516
    • Chapman, P.B.1
  • 3
    • 80053154225 scopus 로고    scopus 로고
    • Phase I/II study to assess safety pharmacokinetics and efficacy of the oral MEK 1/2 inhibitor GSK1120212 (GSK212) dosed in combination with the oral BRAF inhibitor GSK2118436 (GSK436) [abstract]
    • Infante, J. R. et al. Phase I/II study to assess safety, pharmacokinetics, and efficacy of the oral MEK 1/2 inhibitor GSK1120212 (GSK212) dosed in combination with the oral BRAF inhibitor GSK2118436 (GSK436) [abstract]. J. Clin. Oncol. 29 (Suppl.), CRA8503J (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.SUPPL.
    • Infante, J.R.1
  • 4
    • 79958066836 scopus 로고    scopus 로고
    • KIT as a therapeutic target in metastatic melanoma
    • Carvajal, R. D. et al. KIT as a therapeutic target in metastatic melanoma. JAMA. 305, 2327-2334 (2011).
    • (2011) JAMA , vol.305 , pp. 2327-2334
    • Carvajal, R.D.1
  • 5
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    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi, F. S. et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
    • (2010) N. Engl. J. Med. , vol.363 , pp. 711-723
    • Hodi, F.S.1
  • 6
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert, C. et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364, 2517-2526 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2517-2526
    • Robert, C.1
  • 7
    • 77957273591 scopus 로고    scopus 로고
    • Improved endpoints for cancer immunotherapy trials
    • Hoos, A. et al. Improved endpoints for cancer immunotherapy trials. J. Natl Cancer Inst. 102, 1388-1397 (2010).
    • (2010) J. Natl Cancer Inst. , vol.102 , pp. 1388-1397
    • Hoos, A.1
  • 9
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    • Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
    • Brahmer, J. R. et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 28, 3167-3175 (2010).
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    • Brahmer, J.R.1
  • 10
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    • Ulceration and stage are predictive of interferon efficacy in melanoma: Results of the phase III adjuvant trials EORTC 18952 and EORTC 18991
    • doi:10.1016/j.ejca.2011.09.028
    • Eggermont, A. M. et al. Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991. Eur. J. Cancer. doi:10.1016/j.ejca.2011.09.028
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.