Variant within CELSR2/PSRC1/SORT1, but not within CILP2/PBX4, PCSK9 and APOB genes, has a potential to influence statin treatment efficacy

Journal of Applied Biomedicine

Volumn 10, Issue 1, 2012, Pages 19-28

  Hubácek, Jaroslav Alois ^a,b   Adámková, Věra ^a,b   Lánská, Věra ^a   Dlouhá, Dana ^a   Rynekrová, Jitka ^a   Zlatohlávek, Lukáš ^c   Prusíková, Martina ^c   Ceška, Richard ^c   Vrablík, Michal ^c  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

APOB; CELSR2 PSRC1 SORT1; CILP2 PBX4; Dyslipidemia; Gene variants; PCSK9; Pharmacogenetics; Statins; Treatment efficacy

Indexed keywords

APOLIPOPROTEIN B; ATORVASTATIN; CARTILAGE INTERMEDIATE LAYER PROTEIN 2; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; PROTEIN; SIMVASTATIN; SORTILIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFICACY; DYSLIPIDEMIA; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; RETROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT DURATION; TREATMENT OUTCOME; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84856597947     PISSN: 1214021X     EISSN: 12140287     Source Type: Journal    
DOI: 10.2478/v10136-012-0001-3     Document Type: Article

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