메뉴 건너뛰기




Volumn 75, Issue 3, 2012, Pages 348-352

Docetaxel-carboplatin chemotherapy combined with cetuximab in patients with locally advanced or metastatic non small-cell lung cancer (NSCLC)-Results of the nonrandomised phase II study TaxErb

Author keywords

Advanced; Carboplatin; Cetuximab; Docetaxel; First line; Metastatic; Non small cell lung cancer; Weekly

Indexed keywords

CARBOPLATIN; CETUXIMAB; DOCETAXEL;

EID: 84856576793     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2011.08.006     Document Type: Article
Times cited : (7)

References (46)
  • 2
    • 74949133978 scopus 로고    scopus 로고
    • American society of clinical oncology clinical practice guideline update on chemotherapy for stage IV non-small cell lung cancer
    • Azzoli C.G., et al. American society of clinical oncology clinical practice guideline update on chemotherapy for stage IV non-small cell lung cancer. J Clin Oncol 2009, 27(36):6251-6266.
    • (2009) J Clin Oncol , vol.27 , Issue.36 , pp. 6251-6266
    • Azzoli, C.G.1
  • 3
    • 77949478600 scopus 로고    scopus 로고
    • Prävention, diagnostik therapie und nachsorge des lungenkarzinoms
    • Goeckenjan G., Sitter H., Thomas M., et al. Prävention, diagnostik therapie und nachsorge des lungenkarzinoms. Pneumologie 2010, 64(Suppl. 2):e1-e164.
    • (2010) Pneumologie , vol.64 , Issue.SUPPL. 2
    • Goeckenjan, G.1    Sitter, H.2    Thomas, M.3
  • 4
    • 0036500831 scopus 로고    scopus 로고
    • Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy
    • Herbst R.S., Shin D.M. Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy. Cancer 2002, 94:1593-1611.
    • (2002) Cancer , vol.94 , pp. 1593-1611
    • Herbst, R.S.1    Shin, D.M.2
  • 5
    • 77949886293 scopus 로고    scopus 로고
    • Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small cell lung cancer
    • Khambata-Ford S., Harbison C., Hart L., et al. Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small cell lung cancer. J Clin Oncol 2010, 28:918-927.
    • (2010) J Clin Oncol , vol.28 , pp. 918-927
    • Khambata-Ford, S.1    Harbison, C.2    Hart, L.3
  • 8
    • 0033580853 scopus 로고    scopus 로고
    • Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for akt activation
    • Gibson S., Tu S., Oyer R., et al. Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for akt activation. J Ciol Chem 1999, 274:17612-17618.
    • (1999) J Ciol Chem , vol.274 , pp. 17612-17618
    • Gibson, S.1    Tu, S.2    Oyer, R.3
  • 9
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd F.A., Pereira J.R., Ciuleanu T., et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005, 353:123-132.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Pereira, J.R.2    Ciuleanu, T.3
  • 10
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial
    • Kim E., Hirsch V., Mok T., et al. Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet 2008, 372:1809-1818.
    • (2008) Lancet , vol.372 , pp. 1809-1818
    • Kim, E.1    Hirsch, V.2    Mok, T.3
  • 11
    • 1542713370 scopus 로고    scopus 로고
    • Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2
    • Herbst R.S., Giaccone G., Schiller J.H., et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2. J Clin Oncol 2004, 22:785-794.
    • (2004) J Clin Oncol , vol.22 , pp. 785-794
    • Herbst, R.S.1    Giaccone, G.2    Schiller, J.H.3
  • 12
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1
    • Giaccone G., Herbst R.S., Manegold C., et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1. J Clin Oncol 2004, 22:777-784.
    • (2004) J Clin Oncol , vol.22 , pp. 777-784
    • Giaccone, G.1    Herbst, R.S.2    Manegold, C.3
  • 13
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small cell lung cancer: the tarceva lung cancer investigation trial
    • Gatzemeier U., Pluzanska A., Szczesna A., et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small cell lung cancer: the tarceva lung cancer investigation trial. J Clin Oncol 2007, 25:1545-1552.
    • (2007) J Clin Oncol , vol.25 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 14
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
    • Herbst R.S., Prager D., Fehrenbacher L., et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005, 23:5892-5899.
    • (2005) J Clin Oncol , vol.23 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Fehrenbacher, L.3
  • 15
    • 45149084723 scopus 로고    scopus 로고
    • Firstline gefitinib in patients with advanced non-small cell lung cancer harboring somatic EGFR mutations
    • Sequist L., Martins R.G., Spigel D., et al. Firstline gefitinib in patients with advanced non-small cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 2008, 26:2442-2449.
    • (2008) J Clin Oncol , vol.26 , pp. 2442-2449
    • Sequist, L.1    Martins, R.G.2    Spigel, D.3
  • 16
    • 0028819660 scopus 로고
    • Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in human tumor xenograft model
    • Goldstein N.I., Prewett M., Zuklys K., et al. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in human tumor xenograft model. Clin Cancer Res 1995, 1:1311-1318.
    • (1995) Clin Cancer Res , vol.1 , pp. 1311-1318
    • Goldstein, N.I.1    Prewett, M.2    Zuklys, K.3
  • 17
    • 23844491524 scopus 로고    scopus 로고
    • Differential effects of gefitinib and cetuximab on non small-cell lung cancers bearing epidermal growth factor receptor mutations
    • Mukohara T., Engelman J.A., Hanna N.H., et al. Differential effects of gefitinib and cetuximab on non small-cell lung cancers bearing epidermal growth factor receptor mutations. J Natl Cancer Inst 2005, 97:1185-1194.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1185-1194
    • Mukohara, T.1    Engelman, J.A.2    Hanna, N.H.3
  • 18
    • 33947420511 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines
    • Kurai J., Chikumi H., Hashimoto K., et al. Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines. Clin Cancer Res 2007, 13:1552-1561.
    • (2007) Clin Cancer Res , vol.13 , pp. 1552-1561
    • Kurai, J.1    Chikumi, H.2    Hashimoto, K.3
  • 19
    • 33846564399 scopus 로고    scopus 로고
    • Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma
    • Kawaguchi Y., Kono K., Mimura K., et al. Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma. Int J Cancer 2007, 120:781-787.
    • (2007) Int J Cancer , vol.120 , pp. 781-787
    • Kawaguchi, Y.1    Kono, K.2    Mimura, K.3
  • 20
    • 33144484457 scopus 로고    scopus 로고
    • Multicenter phase I/II study of cetuximab with paclitaxel and carboplatin in untreated patients with stage IV non-small cell lung cancer
    • Thienelt C.D., Bunn P.A., Hanna N., Rosenberg A., Needle M.N., Long M.E., et al. Multicenter phase I/II study of cetuximab with paclitaxel and carboplatin in untreated patients with stage IV non-small cell lung cancer. J Clin Oncol 2005, 23:8786-8793.
    • (2005) J Clin Oncol , vol.23 , pp. 8786-8793
    • Thienelt, C.D.1    Bunn, P.A.2    Hanna, N.3    Rosenberg, A.4    Needle, M.N.5    Long, M.E.6
  • 21
    • 58949087252 scopus 로고    scopus 로고
    • Phase II study of paclitaxel, carboplatin, and cetuximab as first line treatment, for patients with advanced non-small cell lung cancer (NSCLC): results of OPN-017
    • Borghaei H., Langer C.J., Millenson M., Ruth K.J., Litwin S., Tuttle H., et al. Phase II study of paclitaxel, carboplatin, and cetuximab as first line treatment, for patients with advanced non-small cell lung cancer (NSCLC): results of OPN-017. J Thorac Oncol 2008, 3:1286-1292.
    • (2008) J Thorac Oncol , vol.3 , pp. 1286-1292
    • Borghaei, H.1    Langer, C.J.2    Millenson, M.3    Ruth, K.J.4    Litwin, S.5    Tuttle, H.6
  • 22
    • 55549127901 scopus 로고    scopus 로고
    • Cetuximab in combination with carboplatin and docetaxel for patients with metastatic or advanced-stage nonsmall cell lung cancer: a multicenter phase 2 study
    • Belani C.P., Schreeder M.T., Steis R.G., Guidice R.A., Marsland T.A., Butler E.H., et al. Cetuximab in combination with carboplatin and docetaxel for patients with metastatic or advanced-stage nonsmall cell lung cancer: a multicenter phase 2 study. Cancer 2008, 113:2512-2517.
    • (2008) Cancer , vol.113 , pp. 2512-2517
    • Belani, C.P.1    Schreeder, M.T.2    Steis, R.G.3    Guidice, R.A.4    Marsland, T.A.5    Butler, E.H.6
  • 23
    • 38849114239 scopus 로고    scopus 로고
    • Randomized phase II study of cetuximab plus cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small cell lung cancer
    • Rosell R., Robinet G., Szczesna A., Ramlau R., Constenla M., Mennecier B.C., et al. Randomized phase II study of cetuximab plus cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small cell lung cancer. Ann Oncol 2008, 19:362-369.
    • (2008) Ann Oncol , vol.19 , pp. 362-369
    • Rosell, R.1    Robinet, G.2    Szczesna, A.3    Ramlau, R.4    Constenla, M.5    Mennecier, B.C.6
  • 24
    • 37649022615 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine plus cisplatin, with or without cetuximab, as first-line therapy for patients with advanced or metastatic non-small cell lung cancer
    • Butts C.A., Bodkin D., Middleman E.L., Englund C.W., Ellison D., Alam Y., et al. Randomized phase II study of gemcitabine plus cisplatin, with or without cetuximab, as first-line therapy for patients with advanced or metastatic non-small cell lung cancer. J Clin Oncol 2007, 25:5777-5784.
    • (2007) J Clin Oncol , vol.25 , pp. 5777-5784
    • Butts, C.A.1    Bodkin, D.2    Middleman, E.L.3    Englund, C.W.4    Ellison, D.5    Alam, Y.6
  • 25
    • 37649016023 scopus 로고    scopus 로고
    • A phase II randomized selection trial evaluating concurrent chemotherapy plus cetuximab or chemotherapy followed by cetuximab in patients with advanced non-small cell lung cancer (NSCLC): final report of SWOG 0342
    • [Abstract 7545]
    • Herbst R.S., Chansky K., Kelly K., Atkins J.N., Davies A.M., Dakhil S.R., et al. A phase II randomized selection trial evaluating concurrent chemotherapy plus cetuximab or chemotherapy followed by cetuximab in patients with advanced non-small cell lung cancer (NSCLC): final report of SWOG 0342. J Clin Oncol 2007, 25(18S):395s. [Abstract 7545].
    • (2007) J Clin Oncol , vol.25 , Issue.18 S
    • Herbst, R.S.1    Chansky, K.2    Kelly, K.3    Atkins, J.N.4    Davies, A.M.5    Dakhil, S.R.6
  • 26
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced NSCLC (FLEX): an open-label randomised phase III trial
    • Pirker R., Pereira J.R., Szczesna A., et al. Cetuximab plus chemotherapy in patients with advanced NSCLC (FLEX): an open-label randomised phase III trial. Lancet 2009, 373:1515-1531.
    • (2009) Lancet , vol.373 , pp. 1515-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3
  • 27
    • 77949891126 scopus 로고    scopus 로고
    • Cetuximab and first-line taxane/carboplatin chemotherapy in advanced NSCLC: results of the randomised multicenter phase III trial BMS099
    • Lynch T., Patel T., Dreisbach L., et al. Cetuximab and first-line taxane/carboplatin chemotherapy in advanced NSCLC: results of the randomised multicenter phase III trial BMS099. J Clin Oncol 2010, 28(6):911-917.
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 911-917
    • Lynch, T.1    Patel, T.2    Dreisbach, L.3
  • 28
    • 33750485379 scopus 로고    scopus 로고
    • Weekly docetaxel as second line chemotherapy for advanced non-small-cell lung cancer: meta-analysis of randomized trials
    • Bria E., Cuppone F., Ciccarese M., et al. Weekly docetaxel as second line chemotherapy for advanced non-small-cell lung cancer: meta-analysis of randomized trials. Cancer Treat Rev 2006, 32:583-587.
    • (2006) Cancer Treat Rev , vol.32 , pp. 583-587
    • Bria, E.1    Cuppone, F.2    Ciccarese, M.3
  • 29
    • 33846849272 scopus 로고    scopus 로고
    • A phase I dose escalation study of weekly docetaxel and carboplatin in elderly patients with nonsmall cell lung cancer
    • Kaira K., Tsuchiya S., Sunaga N., Yanagitani N., et al. A phase I dose escalation study of weekly docetaxel and carboplatin in elderly patients with nonsmall cell lung cancer. Am J Clin Oncol 2007, 30:51-56.
    • (2007) Am J Clin Oncol , vol.30 , pp. 51-56
    • Kaira, K.1    Tsuchiya, S.2    Sunaga, N.3    Yanagitani, N.4
  • 30
    • 34247847907 scopus 로고    scopus 로고
    • Phase II study of carboplatin combined with biweekly docetaxel for advanced non-small cell lung cancer
    • Ishimoto O., Sugawara S., Inoue A., et al. Phase II study of carboplatin combined with biweekly docetaxel for advanced non-small cell lung cancer. J Thorac Oncol. 2006, 1:979-983.
    • (2006) J Thorac Oncol. , vol.1 , pp. 979-983
    • Ishimoto, O.1    Sugawara, S.2    Inoue, A.3
  • 31
    • 18944389851 scopus 로고    scopus 로고
    • Cisplatin and weekly docetaxel as first-line therapy in patients with advanced non-small cell lung cancer a phase II study
    • Tartarone A., Romano G., Iodice G. Cisplatin and weekly docetaxel as first-line therapy in patients with advanced non-small cell lung cancer a phase II study. Tumori 2005, 9:131-134.
    • (2005) Tumori , vol.9 , pp. 131-134
    • Tartarone, A.1    Romano, G.2    Iodice, G.3
  • 32
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organisation of Research and Treatment of Cancer, National Cancer Institute of the United States, National Institute of Canada
    • Therasse P., Arbuck S.G., Eisenhauer E.A., Wanders J., Kaplan R.S., Rubinstein L., et al. New guidelines to evaluate the response to treatment in solid tumors. European Organisation of Research and Treatment of Cancer, National Cancer Institute of the United States, National Institute of Canada. J Natl Cancer Inst 2000, 92:205-221.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-221
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 33
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials 1989, 10:1-10.
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 34
    • 5444235920 scopus 로고    scopus 로고
    • Metaanalysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small-cell lung cancer
    • Hotta K., Matsuo K., Ueoka H., et al. Metaanalysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small-cell lung cancer. J Clin Oncol 2004, 22:3852-3859.
    • (2004) J Clin Oncol , vol.22 , pp. 3852-3859
    • Hotta, K.1    Matsuo, K.2    Ueoka, H.3
  • 35
    • 34347379142 scopus 로고    scopus 로고
    • Cisplatin- versus carboplatin based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis
    • Ardizzoni A., Boni L., Tiseo M., Fossella F.V., Schiller J.H., Paesmans M., et al. Cisplatin- versus carboplatin based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis. J Natl Cancer Inst 2007, 99:847-857.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 847-857
    • Ardizzoni, A.1    Boni, L.2    Tiseo, M.3    Fossella, F.V.4    Schiller, J.H.5    Paesmans, M.6
  • 36
    • 0042413836 scopus 로고    scopus 로고
    • Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group
    • Fossella F., Pereira J.R., von Pawel J., et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. J Clin Oncol 2003, 21:3016-3024.
    • (2003) J Clin Oncol , vol.21 , pp. 3016-3024
    • Fossella, F.1    Pereira, J.R.2    von Pawel, J.3
  • 37
    • 0036810227 scopus 로고    scopus 로고
    • Phase III randomised trial comparing paclitaxel/carboplatin with paclitaxel/cisplatin in patients with advanced non-small-cell lung cancer: a cooperative multinational trial
    • Rosell R., Gatzemeier U., Betticher D.C., et al. Phase III randomised trial comparing paclitaxel/carboplatin with paclitaxel/cisplatin in patients with advanced non-small-cell lung cancer: a cooperative multinational trial. Ann Oncol 2002, 13:1539-1549.
    • (2002) Ann Oncol , vol.13 , pp. 1539-1549
    • Rosell, R.1    Gatzemeier, U.2    Betticher, D.C.3
  • 38
    • 0036843105 scopus 로고    scopus 로고
    • Phase III randomized trial comparing three platinum based doublets in advanced non-small-cell lungcancer
    • Scagliotti G.V., De Marinis F., Rinaldi M., et al. Phase III randomized trial comparing three platinum based doublets in advanced non-small-cell lungcancer. J Clin Oncol 2002, 20:4285-4291.
    • (2002) J Clin Oncol , vol.20 , pp. 4285-4291
    • Scagliotti, G.V.1    De Marinis, F.2    Rinaldi, M.3
  • 39
    • 9144243571 scopus 로고    scopus 로고
    • Cisplatin versus carboplatin in combination with mitomycin and vinblastine in advanced non small cell lung cancer: a multicenter, randomized phase III trial
    • Paccagnella A., Favaretto A., Oniga F., et al. Cisplatin versus carboplatin in combination with mitomycin and vinblastine in advanced non small cell lung cancer: a multicenter, randomized phase III trial. Lung Cancer 2004, 43:83-91.
    • (2004) Lung Cancer , vol.43 , pp. 83-91
    • Paccagnella, A.1    Favaretto, A.2    Oniga, F.3
  • 40
    • 25444511051 scopus 로고    scopus 로고
    • Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer
    • Belani C.P., Lee J.S., Socinski M.A., et al. Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer. Ann Oncol 2005, 16:1069-1075.
    • (2005) Ann Oncol , vol.16 , pp. 1069-1075
    • Belani, C.P.1    Lee, J.S.2    Socinski, M.A.3
  • 41
    • 16644398719 scopus 로고    scopus 로고
    • Gemcitabine plus carboplatin versus mitomycin, ifosfamide and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group
    • Rudd R.M., Gower N.H., Spiro S.G., et al. Gemcitabine plus carboplatin versus mitomycin, ifosfamide and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group. J Clin Oncol 2005, 23:142-153.
    • (2005) J Clin Oncol , vol.23 , pp. 142-153
    • Rudd, R.M.1    Gower, N.H.2    Spiro, S.G.3
  • 42
    • 33745632406 scopus 로고    scopus 로고
    • A phase III trial of docetaxel/carboplatin versus mitomycin C/ifosfamide/cisplatin (MIC) or mitomycin C/vinblastine/cisplatin (MVP) in patients with advanced non-small-cell lung cancer: a randomised multicentre trial of the British Thoracic Oncology Group (BTOG1)
    • Booton R., Lorigan P., Anderson H., et al. A phase III trial of docetaxel/carboplatin versus mitomycin C/ifosfamide/cisplatin (MIC) or mitomycin C/vinblastine/cisplatin (MVP) in patients with advanced non-small-cell lung cancer: a randomised multicentre trial of the British Thoracic Oncology Group (BTOG1). Ann Oncol 2006, 17:1111-1119.
    • (2006) Ann Oncol , vol.17 , pp. 1111-1119
    • Booton, R.1    Lorigan, P.2    Anderson, H.3
  • 43
    • 33745893529 scopus 로고    scopus 로고
    • Effect of chemotherapy for advanced non-small cell lung cancer on patients' quality of life: a randomized controlled trial
    • Belani C.P., Pereira J.R., von Pawel J., et al. Effect of chemotherapy for advanced non-small cell lung cancer on patients' quality of life: a randomized controlled trial. Lung Cancer 2006, 53:231-239.
    • (2006) Lung Cancer , vol.53 , pp. 231-239
    • Belani, C.P.1    Pereira, J.R.2    von Pawel, J.3
  • 44
    • 68949124435 scopus 로고    scopus 로고
    • Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): data from the FLEX study
    • [Abstract 8007]
    • O'Byrne K.J., Bondarenko I., Barrios C., Eschbach C., Martens U., Hotko Y., et al. Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): data from the FLEX study. J Clin Oncol 2009, 27(15S). [Abstract 8007].
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • O'Byrne, K.J.1    Bondarenko, I.2    Barrios, C.3    Eschbach, C.4    Martens, U.5    Hotko, Y.6
  • 45
    • 78650694719 scopus 로고    scopus 로고
    • First-cycle rash and survival in patients with advanced non-small-cell lung cancer receiving cetuximab in combination with first-line chemotherapy: a subgroup analysis of data from the FLEX phase 3 study
    • January
    • Gatzemeier U., von Pawel J., Vynnychenko I., Zatloukal P., et al. First-cycle rash and survival in patients with advanced non-small-cell lung cancer receiving cetuximab in combination with first-line chemotherapy: a subgroup analysis of data from the FLEX phase 3 study. Lancet Oncol 2011, 12(January (1)):30-37.
    • (2011) Lancet Oncol , vol.12 , Issue.1 , pp. 30-37
    • Gatzemeier, U.1    von Pawel, J.2    Vynnychenko, I.3    Zatloukal, P.4
  • 46
    • 84856579849 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) expression as a predictor of survival for first-line chemotherapy plus cetuximab in FLEX study patients with advanced non-small cell lung cancer (NSCLC)
    • In: IASLC: 14th. WCLC , abstract 001.06.
    • Pirker R, Paz Ares L, Eberhardt WE, Krzakowski M, Störkel S, Heeger S, et al. Epidermal growth factor receptor (EGFR) expression as a predictor of survival for first-line chemotherapy plus cetuximab in FLEX study patients with advanced non-small cell lung cancer (NSCLC). In: IASLC: 14th. WCLC 2011, abstract 001.06. http://www.2011worldlungcancer.org/abstracts.
    • (2011)
    • Pirker, R.1    Paz Ares, L.2    Eberhardt, W.E.3    Krzakowski, M.4    Störkel, S.5    Heeger, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.