One day of motor training with amphetamine impairs motor recovery following spinal cord injury

Experimental Neurology

Volumn 233, Issue 2, 2012, Pages 693-707

  Wong, Jamie K ^a   Steward, Oswald ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CERVICAL SPINE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FUNCTIONAL ASSESSMENT; GRIP STRENGTH; HISTOPATHOLOGY; LOCOMOTION; MALE; MOTOR ACTIVITY; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MUSCLE TRAINING; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; TASK PERFORMANCE; THORACIC SPINE; WALKING;

AMPHETAMINE; ANIMALS; CERVICAL VERTEBRAE; COMBINED MODALITY THERAPY; EXERCISE THERAPY; FEMALE; MALE; MOTOR ACTIVITY; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; TIME FACTORS;

EID: 84856553555     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.08.011     Document Type: Article

References (28)

1. Anderson K.D., Gunawan A., Steward O. Quantitative assessment of forelimb motor function after cervical spinal cord injury in rats: relationship to the corticospinal tract. Exp. Neurol. 2005, 194:161-174.
2. Anderson K.D., Gunawan A., Steward O. Spinal pathways involved in the control of forelimb motor function in rats. Exp. Neurol. 2007, 206:318-331.
3. Ballermann M., Fouad K. Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers. Eur. J. Neurosci. 2006, 23:1988-1996.
4. Bareyre F.M., Kerschensteiner M., Raineteau O., Metterleiter T.C., Weinmann O., Schwab M.E. The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nat. Neurosci. 2004, 7:269-277.
5. Basso D.M., Beattie M.S., Bresnahan J.C. A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 1995, 12:1-21.
6. Bourdelais A., Kalivas P.W. Amphetamine lowers extracellular GABA concentration in the ventral pallidum. Brain Res. 1990, 516:132-136.
7. Boyeson M.G., Feeney D.M. Intraventricular norepinephrine facilitates motor recovery following sensorimotor cortex injury. Pharmacol. Biochem. Behav. 1990, 35:497-501.
8. Engesser-Cesar C., Anderson A.J., Basso D.M., Edgerton V.R., Cotman C. Voluntary wheel running improves recovery from a moderate spinal cord injury. J. Neurotrauma 2005, 22:157-171.
9. Feeney D.M., Westerberg V.S. Norepinephrine and brain damage: alpha noradrenergic pharmacology alters functional recovery after cortical trauma. Can. J. Psychol. 1990, 44:233-252.
10. Feeney D.M., Gonzalez A., Law W.A. Amphetamine, haloperidol, and experience interact to affect rate of recovery after motor cortex injury. Science 1982, 217:855-857.
11. Fouad K., Pedersen V., Schwab M.E., Brösamle C. Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr. Biol. 2001, 11:1766-1770.
12. Gulino R., Dimartino M., Casabona A., Lombardo S.A., Perciavalle V. Synaptic plasticity modulates the spontaneous recovery of locomotion after spinal cord hemisection. Neurosci. Res. 2007, 57:148-156.
13. Lovely R.G., Gregor R.J., Roy R.R., Edgerton V.R. Effects of training on the recovery of full-weight-bearing stepping in the adult spinal cat. Exp. Neurol. 1986, 92:421-435.
14. Luo C.X., Jiang J., Zhou Q.G., Zhu X.J., Wang W., Zhang Z.J., Han X., Zhu D.Y. Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke. J. Neurosci. Res. 2007, 85:1637-1646.
15. Matsuda F., Sakakima H., Yoshida Y. The effects of early exercise on brain damage and recovery after focal cerebral infarction in rats. Acta Physiol. 2010, 201:275-287.
16. Mautes A.E.M., Weinzierl M.R., Donovan F., Noble L.J. Vascular events after spinal cord injury: contribution to secondary pathogenesis. Phys. Ther. 2000, 80:673-687.
17. Raineteau O., Schwab M.E. Plasticity of motor systems after incomplete spinal cord injury. Nat. Rev. Neurosci. 2001, 2:263-273.
18. Ramic M., Emerick A.J., Bollnow M.R., O'Brien T.E., Tsai S., Kartje G.L. Axonal plasticity is associated with motor recovery following amphetamine treatment combined with rehabilitation after brain injury in the adult rat. Brain Res. 2006, 1111:176-186.
19. Saruhashi Y., Young W., Perkins R. The recovery of 5-HT immunoreactivity in lumbosacral spinal cord and locomotor function after thoracic hemisection. Exp. Neurol. 1996, 139:203-213.
20. Schnell L., Fearn S., Klassen H., Schwab M.E., Perry V.H. Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord. Eur. J. Neurosci. 1999, 11:3648-3658.
21. Seiden L.S., Sabol K.E., Ricaurte G.A. Amphetamine: effects on catecholamine systems and behavior. Annu. Rev. Pharmacol. Toxicol. 1993, 33:639-677.
22. Silveira E.M.S., Rodrigues M.F., Krause M.S., Vianna D.R., Almeida B.S., Rossato J.S., Oliveira L.P., Curi R., Homem de Bittencourt P.I. Acute exercise stimulates macrophage function: possible role of NF-kB pathways. Cell. Biochem. Funct. 2007, 25:63-73.
23. Stroemer R.P., Kent T.A., Hulsebosch C.E. Enhanced neocortical neural sprouting, synaptogenesis, and behavioral recovery with d-amphetamine therapy after neocortical infarction in rats. Stroke 1998, 29:2381-2395.
24. Tegenthoff M., Cornelius B., Pleger B., Malin J.P., Schwenkreis P. Amphetamine enhances training-induced motor cortex plasticity. Acta Neurol. Scand. 2004, 109:330-336.
25. Thomas D.M., Dowgiert J., Geddes T.J., Francescutti-Verbeem D., Liu X., Kuhn D.M. Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines. Neurosci. Lett. 2004, 367:349-354.
26. Weinstock M., Razin M., Schorer-Apelbaum D., Men D., McCarty R. Gender differences in sympathoadrenal activity in rats at rest and in response to footshock stress. Int. J. Dev. Neurosci. 1998, 16:289-295.
27. Wong J.K., Sharp K., Steward O. A straight alley version of the BBB locomotor scale. Exp. Neurol. 2009, 217:417-420.
28. Ying Z., Roy R.R., Edgerton V.R., Gómez-Pinilla F. Exercise restores levels of neurotrophins and synaptic plasticity following spinal cord injury. Exp. Neurol. 2005, 193:411-419.