-
1
-
-
80051580618
-
Cancer statistics 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA A Cancer J Clin. 2011;61:212-36.
-
(2011)
CA A Cancer J Clin.
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
2
-
-
11844273481
-
-
World cancer report. Lyon: International Agency for Research on Cancer
-
Colorectal Cancer. In: Stewart BW, Kleihues P, editors. World cancer report. Lyon: International Agency for Research on Cancer, 2003. pp 198-2.
-
(2003)
Colorectal Cancer
, pp. 198-192
-
-
Stewart, B.W.1
Kleihues, P.2
-
3
-
-
11844273837
-
-
Weitz J, Koch M, Debus J, Hohler T, Galle PR, Buchler MW. Colorectal Cancer. Lancet. 2005;365:153-65.
-
(2005)
Lancet
, vol.365
, pp. 153-165
-
-
Weitz, J.1
Koch, M.2
Debus, J.3
Hohler, T.4
Galle, P.R.5
Buchler, M.W.6
Cancer, C.7
-
4
-
-
1542348477
-
Cancer statistics
-
Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, Feuer EJ, Thun MJ. Cancer statistics, 2004. CA Cancer J Clin. 2004;54:8-29.
-
(2004)
CA Cancer J Clin
, vol.2004
, Issue.54
, pp. 8-29
-
-
Jemal, A.1
Tiwari, R.C.2
Murray, T.3
Ghafoor, A.4
Samuels, A.5
Ward, E.6
Feuer, E.J.7
Thun, M.J.8
-
5
-
-
2642552668
-
Phase I/II mutant p53 vaccination in advanced malignancies
-
Behrens RJ, Achtar M, Herrin V, Gause B, Bernstein S, Brent- Steele T, Maruffi C, Yancey M, Khleif SN: Phase I/II mutant p53 vaccination in advanced malignancies. Proc Am Soc Clin Oncol. 2003;22:186.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 186
-
-
Behrens, R.J.1
Achtar, M.2
Herrin, V.3
Gause, B.4
Bernstein, S.5
Brent- Steele, T.6
Maruffi, C.7
Yancey, M.8
Khleif, S.N.9
-
6
-
-
24644522923
-
Immunization with mutant p53- and K-ras-derived peptides in cancer patients: Immune response and clinical outcome
-
Carbone DP, Ciernik IF, Kelley MJ, Smith MC, Nadaf S, Kavanaugh D, Maher VE, Stipanov M, Contois D, Johnson BE, Pendleton CD, Seifert B, Carter C, Read EJ, Greenblatt J, Top LE, Kelsey MI, Minna JD, Berzofsky JA: Immunization with mutant p53- and K-ras-derived peptides in cancer patients: Immune response and clinical outcome. J Clin Oncol. 2005;23:5099-7.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5099-5097
-
-
Carbone, D.P.1
Ciernik, I.F.2
Kelley, M.J.3
Smith, M.C.4
Nadaf, S.5
Kavanaugh, D.6
Maher, V.E.7
Stipanov, M.8
Contois, D.9
Johnson, B.E.10
Pendleton, C.D.11
Seifert, B.12
Carter, C.13
Read, E.J.14
Greenblatt, J.15
Top, L.E.16
Kelsey, M.I.17
Minna, J.D.18
Berzofsky, J.A.19
-
7
-
-
21344434858
-
Mutant P53 vaccination of patients with advanced cancers generates specific immunological responses
-
Ibrahim RA, Achtar MS, Herrin VE, Gause B, Bernstein SA, Brent-Steel TB, Maruffi CM, Berzofsky JA, Khleif SN: Mutant P53 vaccination of patients with advanced cancers generates specific immunological responses. J Clin Oncol ASCO Ann Meet Proc. 2004;22:2521.
-
J Clin Oncol ASCO Ann Meet Proc
, vol.2004
, Issue.22
, pp. 2521
-
-
Ibrahim, R.A.1
Achtar, M.S.2
Herrin, V.E.3
Gause, B.4
Bernstein, S.A.5
Brent-Steel, T.B.6
Maruffi, C.M.7
Berzofsky, J.A.8
Khleif, S.N.9
-
8
-
-
0035992254
-
Active specific immunotherapy with a β-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: Antibody response is associated with improved survival
-
Moulton HM, Yoshihara PH, Mason DH, Iversen PL, Triozzi PL. Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: Antibody response is associated with improved survival. Clin Cancer Res. 2002;8:2044-51. (Pubitemid 34753572)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.7
, pp. 2044-2051
-
-
Moulton, H.M.1
Yoshihara, P.H.2
Mason, D.H.3
Iversen, P.L.4
Triozzi, P.L.5
-
9
-
-
0036847668
-
Dendritic cells pulsed with HER-2/neu-derived peptides can induce specific T-cell responses in patients with gastric cancer
-
Kono K, Takahashi A, Sugai H, Fujii H, Choudhury AR, Kiessling R, Matsumoto Y. Dendritic cells pulsed with HER-2/ neu-derived peptides can induce specific T-cell responses in patients with gastric cancer. Clin Cancer Res. 2002;8: 3394-400. (Pubitemid 35340713)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.11
, pp. 3394-3400
-
-
Kono, K.1
Takahashi, A.2
Sugai, H.3
Fujii, H.4
Choudhury, A.R.5
Kiessling, R.6
Matsumoto, Y.7
-
10
-
-
33745758097
-
Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer
-
Tsuruma T, Hata F, Torigoe T, Furuhata T, Idenoue S, Kurotaki T, Yamamoto M, Yagihashi A, Ohmura T, Yamaguchi K, Katsuramaki T, Yasoshima T, Sasaki K, Mizushima Y, Minamida H, Kimura H, Akiyama M, Hirohashi Y, Asanuma H, Tamura Y, Shimozawa K, Sato N, Hirata K: Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer. J Transl Med. 2004;2:19.
-
(2004)
J Transl Med
, vol.2
, pp. 19
-
-
Tsuruma, T.1
Hata, F.2
Torigoe, T.3
Furuhata, T.4
Idenoue, S.5
Kurotaki, T.6
Yamamoto, M.7
Yagihashi, A.8
Ohmura, T.9
Yamaguchi, K.10
Katsuramaki, T.11
Yasoshima, T.12
Sasaki, K.13
Mizushima, Y.14
Minamida, H.15
Kimura, H.16
Akiyama, M.17
Hirohashi, Y.18
Asanuma, H.19
Tamura, Y.20
Shimozawa, K.21
Sato, N.22
Hirata, K.23
more..
-
11
-
-
20044364936
-
Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas
-
Marshall JL, Gulley JL, Arlen PM, Beetham PK, Tsang K-Y, Slack R, Hodge JW, Doren S, Grosenbach DW, Hwang J, Fox E, Odogwu L, Park S, Panicali D, Schlom J: Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcinomas. J Clin Oncol. 2005;23:720-1.
-
(2005)
J Clin Oncol
, vol.23
, pp. 720-721
-
-
Marshall, J.L.1
Gulley, J.L.2
Arlen, P.M.3
Beetham, P.K.4
Tsang, K.-Y.5
Slack, R.6
Hodge, J.W.7
Doren, S.8
Grosenbach, D.W.9
Hwang, J.10
Fox, E.11
Odogwu, L.12
Park, S.13
Panicali, D.14
Schlom, J.15
-
12
-
-
0036726329
-
Expression of molecular marker genes in various types of normal tissue: Implication for detection of micrometastases
-
Nagao K, Hisatomi H, Hirata H, Yamamoto S, Hikiji K, Yamamoto M, Kanamaru T. Expression of molecular marker genes in various types of normal tissue: Implication for detection of micrometastases. Int J Mol Med. 2002;10:307-10.
-
(2002)
Int J Mol Med
, vol.10
, pp. 307-310
-
-
Nagao, K.1
Hisatomi, H.2
Hirata, H.3
Yamamoto, S.4
Hikiji, K.5
Yamamoto, M.6
Kanamaru, T.7
-
13
-
-
0031904274
-
Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients
-
Bostick PJ, Chatterjee S, Chi DD, Huynh KT, Giuliano AE, Cote R, Hoon DS. Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients. J Clin Oncol. 1998;16:2632-40.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2632-3640
-
-
Bostick, P.J.1
Chatterjee, S.2
Chi, D.D.3
Huynh, K.T.4
Giuliano, A.E.5
Cote, R.6
Hoon, D.S.7
-
14
-
-
34547683572
-
Different forms of helper tolerance to carcinoembryonic antigen: Ignorance and regulation
-
DOI 10.1158/1078-0432.CCR-07-0721
-
Pickford WJ, Watson AJ, Barker RN. Different forms of helper tolerance to carcinoembryonic antigen: Ignorance and regulation. Clin Cancer Res. 2007;13:4528-37. (Pubitemid 47219723)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.15
, pp. 4528-4537
-
-
Pickford, W.J.1
Watson, A.J.M.2
Barker, R.N.3
-
15
-
-
85049056837
-
T Cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
-
Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, Davis JL, Morgan RA, Merino MJ, Sherry RM, Hughes MS, Kammula US, Phan GQ, Lim RM, Wank SA, Restifo NP, Robbins PF, Laurencot CM, Rosenberg SA: T Cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2010.
-
Mol Ther 2010
-
-
Parkhurst, M.R.1
Yang, J.C.2
Langan, R.C.3
Dudley, M.E.4
Nathan, D.A.5
Feldman, S.A.6
Davis, J.L.7
Morgan, R.A.8
Merino, M.J.9
Sherry, R.M.10
Hughes, M.S.11
Kammula, U.S.12
Phan, G.Q.13
Lim, R.M.14
Wank, S.A.15
Restifo, N.P.16
Robbins, P.F.17
Laurencot, C.M.18
Rosenberg, S.A.19
-
16
-
-
77749242569
-
Lessons learned from natural infection: Focusing on the design of protective T cell vaccines for HIV/AIDS
-
Ahlers JD, Belyakov IM. Lessons learned from natural infection: Focusing on the design of protective T cell vaccines for HIV/AIDS. Trends Immunol. 2010;31:120-30.
-
(2010)
Trends Immunol
, vol.31
, pp. 120-130
-
-
Ahlers, J.D.1
Belyakov, I.M.2
-
18
-
-
1842509115
-
+ T cell population in different tissues
-
DOI 10.1016/j.vaccine.2003.11.043, PII S0264410X03007680
-
Qimron U, Paul L, Bar-Haim E, Bloushtain N, Eisenbach L, Staats HF, Porgador A. Non-replicating mucosal and systemic vaccines: Quantitative and qualitative differences in the Ag-specific CD8(?) T cell population in different tissues. Vaccine. 2004;22:1390-4. (Pubitemid 38446915)
-
(2004)
Vaccine
, vol.22
, Issue.11-12
, pp. 1390-1394
-
-
Qimron, U.1
Paul, L.2
Bar-Haim, E.3
Bloushtain, N.4
Eisenbach, L.5
Staats, H.F.6
Porgador, A.7
-
19
-
-
0028181865
-
Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo
-
Hamann A, Andrew DP, Jablonski-Westrich D, Holzmann B, Butcher EC. Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo. J Immunol. 1994;152:3282-93.
-
(1994)
J Immunol
, vol.152
, pp. 3282-3293
-
-
Hamann, A.1
Andrew, D.P.2
Jablonski-Westrich, D.3
Holzmann, B.4
Butcher, E.C.5
-
20
-
-
0027237424
-
-
Berg
-
Berlin C, Berg EL, Briskin MJ, Andrew DP, Kilshaw PJ, Holzmann B, Weissman IL, Hamann A, Butcher EC. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell. 1993;74:185-95.
-
(1993)
EL, Briskin MJ, Andrew DP, Kilshaw PJ, Holzmann B, Weissman IL, Hamann A, Butcher EC. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell
, vol.74
, pp. 185-195
-
-
Berlin, C.1
-
21
-
-
0037033376
-
+ T cells activated in cutaneous or mucosal lymphoid tissues
-
DOI 10.1084/jem.20011502
-
Campbell DJ, Butcher EC. Rapid acquisition of tissue-specific homing phenotypes by CD4+ T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med. 2002;195:135-41. (Pubitemid 34074503)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.1
, pp. 135-141
-
-
Campbell, D.J.1
Butcher, E.C.2
-
22
-
-
0030900764
-
The anatomical basis of intestinal immunity
-
Mowat AM, Viney JL. The anatomical basis of intestinal immunity. Immunol Rev. 1997;156:145-66. (Pubitemid 27197200)
-
(1997)
Immunological Reviews
, vol.156
, pp. 145-166
-
-
Mowat, A.McI.1
Viney, J.L.2
-
24
-
-
0033864867
-
+ T lymphocytes by attenuated simian immunodeficiency virus
-
DOI 10.1128/JVI.74.18.8762-8766.2000
-
Cromwell MA, Veazey RS, Altman JD, Mansfield KG, Glickman R, Allen TM, Watkins DI, Lackner AA, Johnson RP. Induction of mucosal homing virus-specific CD8+ T lymphocytes by attenuated simian immunodeficiency virus. J Virol. 2000;74:8762-6. (Pubitemid 30666728)
-
(2000)
Journal of Virology
, vol.74
, Issue.18
, pp. 8762-8766
-
-
Cromwell, M.A.1
Veazey, R.S.2
Altman, J.D.3
Mansfield, K.G.4
Glickman, R.5
Allen, T.M.6
Watkins, D.I.7
Lackner, A.A.8
Johnson, R.P.9
-
25
-
-
0031660670
-
Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein
-
Belyakov IM, Wyatt LS, Ahlers JD, Earl P, Pendleton CD, Kelsall BL, Strober W, Moss B, Berzofsky JA. Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein. J Virol. 1998;72:8264-72. (Pubitemid 28421824)
-
(1998)
Journal of Virology
, vol.72
, Issue.10
, pp. 8264-8272
-
-
Belyakov, I.M.1
Wyatt, L.S.2
Ahlers, J.D.3
Earl, P.4
Pendleton, C.D.5
Kelsall, B.L.6
Strober, W.7
Moss, B.8
Berzofsky, J.A.9
-
26
-
-
0033551132
-
Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity
-
DOI 10.1073/pnas.96.8.4512
-
Belyakov IM, Moss B, Strober W, Berzofsky JA. Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity. Proc Natl Acad Sci USA. 1999;96:4512-7. (Pubitemid 29190367)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.8
, pp. 4512-4517
-
-
Belyakov, I.M.1
Moss, B.2
Strober, W.3
Berzofsky, J.A.4
-
27
-
-
0032535760
-
+ cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administration of IL-12
-
Belyakov IM, Ahlers JD, Brandwein BY, Earl P, Kelsall BL, Moss B, Strober W, Berzofsky JA. The importance of local mucosal HIV-specific CD8+ cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administration of IL-12. J Clin Invest. 1998;102:2072-81. (Pubitemid 29018813)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.12
, pp. 2072-2081
-
-
Belyakov, I.M.1
Ahlers, J.D.2
Brandwein, B.Y.3
Earl, P.4
Kelsall, B.L.5
Moss, B.6
Strober, W.7
Berzofsky, J.A.8
-
28
-
-
0033832073
-
Guanylyl cyclases and signaling by cyclic GMP
-
Lucas KA, Pitari GM, Kazerounian S, Ruiz-Stewart I, Park J, Schulz S, Chepenik KP, Waldman SA. Guanylyl cyclases and signaling by cyclic GMP. Pharmacol Rev. 2000;52:375-414.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 375-414
-
-
Lucas, K.A.1
Pitari, G.M.2
Kazerounian, S.3
Ruiz-Stewart, I.4
Park, J.5
Schulz, S.6
Chepenik, K.P.7
Waldman, S.A.8
-
29
-
-
38349041719
-
Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine
-
Li P, Lin JE, Chervoneva I, Schulz S, Waldman SA, Pitari GM. Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine. Am J Pathol. 2007;171:1847-58.
-
(2007)
Am J Pathol
, vol.171
, pp. 1847-1858
-
-
Li, P.1
Lin, J.E.2
Chervoneva, I.3
Schulz, S.4
Waldman, S.A.5
Pitari, G.M.6
-
30
-
-
72249093342
-
The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling
-
Lin JE, Li P, Snook AE, Schulz S, Dasgupta A, Hyslop TM, Gibbons AV, Marszlowicz G, Pitari GM, Waldman SA. The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. Gastroenterology. 2009;138: 241-54.
-
(2009)
Gastroenterology
, vol.138
, pp. 241-254
-
-
Lin, J.E.1
Li, P.2
Snook, A.E.3
Schulz, S.4
Dasgupta, A.5
Hyslop, T.M.6
Gibbons, A.V.7
Marszlowicz, G.8
Pitari, G.M.9
Waldman, S.A.10
-
31
-
-
0025647794
-
Guanylyl cyclase is a heat-stable enterotoxin receptor
-
Schulz S, Green CK, Yuen PS, Garbers DL. Guanylyl cyclase is a heat-stable enterotoxin receptor. Cell. 1990;63:941-8. (Pubitemid 120034935)
-
(1990)
Cell
, vol.63
, Issue.5
, pp. 941-948
-
-
Schulz, S.1
Green, C.K.2
Yuen, P.S.T.3
Garbers, D.L.4
-
32
-
-
0028329579
-
Distribution of heat-stable enterotoxin/guanylin receptors in the intestinal tract of man and other mammals
-
Krause WJ, Cullingford GL, Freeman RH, Eber SL, Richardson KC, Fok KF, Currie MG, Forte LR. Distribution of heat-stable enterotoxin/guanylin receptors in the intestinal tract of man and other mammals. J Anat. 1994;184(Pt 2):407-17. (Pubitemid 24114601)
-
(1994)
Journal of Anatomy
, vol.184
, Issue.2
, pp. 407-417
-
-
Krause, W.J.1
Cullingford, G.L.2
Freeman, R.H.3
Eber, S.L.4
Richardson, K.C.5
Fok, K.F.6
Currie, M.G.7
Forte, L.R.8
-
33
-
-
0030801587
-
Epitope conservation and immunohistochemical localization of the guanylin/stable toxin peptide receptor, guanylyl cyclase C
-
DOI 10.1002/(SICI)1097-4644(19970915)66:4<500::AID-JCB9>3.0.CO;2-P
-
Nandi A, Bhandari R, Visweswariah SS. Epitope conservation and immunohistochemical localization of the guanylin/stable toxin peptide receptor, guanylyl cyclase C. J Cell Biochem. 1997;66:500-11. (Pubitemid 27377615)
-
(1997)
Journal of Cellular Biochemistry
, vol.66
, Issue.4
, pp. 500-511
-
-
Nandi, A.1
Bhandari, R.2
Visweswariah, S.S.3
-
34
-
-
0031568228
-
Purification, cDNA sequence, and tissue distribution of rat uroguanylin
-
DOI 10.1016/S0167-0115(96)02103-9, PII S0167011596021039
-
Li Z, Perkins AG, Peters MF, Campa MJ, Goy MF. Purification, cDNA sequence, and tissue distribution of rat uroguanylin. Regul Pept. 1997;68:45-56. (Pubitemid 27117802)
-
(1997)
Regulatory Peptides
, vol.68
, Issue.1
, pp. 45-56
-
-
Li, Z.1
Perkins, A.G.2
Peters, M.F.3
Campa, M.J.4
Goy, M.F.5
-
35
-
-
0027180713
-
Ligand-based histochemical localization and capture of cells expressing heat-stable enterotoxin receptors
-
Almenoff JS, Williams SI, Scheving LA, Judd AK, Schoolnik GK. Ligand-based histochemical localization and capture of cells expressing heat-stable enterotoxin receptors. Mol Microbiol. 1993;8:865-73. (Pubitemid 23171468)
-
(1993)
Molecular Microbiology
, vol.8
, Issue.5
, pp. 865-873
-
-
Almenoff, J.S.1
Williams, S.I.2
Scheving, L.A.3
Judd, A.K.4
Schoolnik, G.K.5
-
36
-
-
0001337601
-
The guanylin/STa receptor is expressed in crypts and apical epithelium throughout the mouse intestine
-
DOI 10.1006/bbrc.1996.1286
-
Swenson ES, Mann EA, Jump ML, Witte DP, Giannella RA. The guanylin/STa receptor is expressed in crypts and apical epithelium throughout the mouse intestine. Biochem Biophys Res Commun. 1996;225:1009-14. (Pubitemid 26319218)
-
(1996)
Biochemical and Biophysical Research Communications
, vol.225
, Issue.3
, pp. 1009-1014
-
-
Swenson, E.S.1
Mann, E.A.2
Jump, M.L.3
Witte, D.P.4
Giannella, R.A.5
-
37
-
-
0034456642
-
Expression of GC-C, a receptor-guanylate cyclase, and its endogenous ligands uroguanylin and guanylin along the rostrocaudal axis of the intestine
-
DOI 10.1210/en.141.9.3210
-
Qian X, Prabhakar S, Nandi A, Visweswariah SS, Goy MF. Expression of GC-C, a receptor-guanylate cyclase, and its endogenous ligands uroguanylin and guanylin along the rostrocaudal axis of the intestine. Endocrinology. 2000;141:3210-24. (Pubitemid 32269009)
-
(2000)
Endocrinology
, vol.141
, Issue.9
, pp. 3210-3224
-
-
Qian, X.1
Prabhakar, S.2
Nandi, A.3
Visweswariah, S.S.4
Goy, M.F.5
-
38
-
-
14644392242
-
Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract
-
DOI 10.1016/j.humpath.2004.12.002
-
Birbe R, Palazzo JP, Walters R, Weinberg D, Schulz S, Waldman SA. Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract. Hum Pathol. 2005;36:170-9. (Pubitemid 40313574)
-
(2005)
Human Pathology
, vol.36
, Issue.2
, pp. 170-179
-
-
Birbe, R.1
Palazzo, J.P.2
Walters, R.3
Weinberg, D.4
Schulz, S.5
Waldman, S.A.6
-
39
-
-
0030070525
-
-
Carrithers SL, Parkinson SJ, Goldstein SD, Park PK, Urbanski RW, Waldman SA. Escherichia coli heat-stable enterotoxin receptors. A novel marker for colorectal tumors. Dis Colon Rectum. 1996;39:171-81.
-
(1996)
Escherichia coli heat-stable enterotoxin receptors. A novel marker for colorectal tumors. Dis Colon Rectum
, vol.39
, pp. 171-181
-
-
Carrithers, S.L.1
Parkinson, S.J.2
Goldstein, S.D.3
Park, P.K.4
Urbanski, R.W.5
Waldman, S.A.6
-
40
-
-
0029856172
-
Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues
-
DOI 10.1073/pnas.93.25.14827
-
Carrithers SL, Barber MT, Biswas S, Parkinson SJ, Park PK, Goldstein SD, Waldman SA. Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues. Proc Natl Acad Sci USA. 1996;93:14827-32. (Pubitemid 26419054)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.25
, pp. 14827-14832
-
-
Carrithers, S.L.1
Barber, M.T.2
Biswas, S.3
Parkinson, S.J.4
Park, P.K.5
Goldstein, S.D.6
Waldman, S.A.7
-
41
-
-
0023220836
-
Binding of E. coli heat-stable enterotoxin to rat intestinal brush borders and to basolateral membranes
-
Guarino A, Cohen MB, Overmann G, Thompson MR, Giannella RA. Binding of E. coli heat-stable enterotoxin to rat intestinal brush borders and to basolateral membranes. Dig Dis Sci. 1987;32:1017-26. (Pubitemid 17137984)
-
(1987)
Digestive Diseases and Sciences
, vol.32
, Issue.9
, pp. 1017-1026
-
-
Guarino, A.1
Cohen, M.B.2
Overmann, G.3
-
43
-
-
0028031074
-
Distribution of membrane bound guanylyl cyclases in human intestine
-
Krause G, Bayerl A, Heim JM, Singh S, Gerzer R. Distribution of membrane bound guanylyl cyclases in human intestine. Gut. 1994;35:1250-7. (Pubitemid 24277339)
-
(1994)
Gut
, vol.35
, Issue.9
, pp. 1250-1257
-
-
Krause, G.1
Bayerl, A.2
Heim, J.-M.3
Singh, S.4
Gerzer, R.5
-
44
-
-
0033534114
-
Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer
-
Cagir B, Gelmann A, Park J, Fava T, Tankelevitch A, Bittner EW, Weaver EJ, Palazzo JP, Weinberg D, Fry RD, Waldman SA. Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer. Ann Intern Med. 1999;131:805-12.
-
(1999)
Ann Intern Med
, vol.131
, pp. 805-812
-
-
Cagir, B.1
Gelmann, A.2
Park, J.3
Fava, T.4
Tankelevitch, A.5
Bittner, E.W.6
Weaver, E.J.7
Palazzo, J.P.8
Weinberg, D.9
Fry, R.D.10
Waldman, S.A.11
-
45
-
-
0031938629
-
Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer
-
DOI 10.1007/BF02237484
-
Waldman SA, Cagir B, Rakinic J, Fry RD, Goldstein SD, Isenberg G, Barber M, Biswas S, Minimo C, Palazzo J, Park PK, Weinberg D. Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer. Dis Colon Rectum. 1998;41:310-5. (Pubitemid 28141595)
-
(1998)
Diseases of the Colon and Rectum
, vol.41
, Issue.3
, pp. 310-315
-
-
Waldman, S.A.1
Cagir, B.2
Rakinic, J.3
Fry, R.D.4
Goldstein, S.D.5
Isenberg, G.6
Barber, M.7
Biswas, S.8
Minimo, C.9
Palazzo, J.10
Park, P.K.11
Weinberg, D.12
-
46
-
-
60749102639
-
Association of GUCY2C expression in lymph nodes with time to recurrence and diseasefree survival in pN0 colorectal cancer
-
Waldman SA, Hyslop T, Schulz S, Barkun A, Nielsen K, Haaf J, Bonaccorso C, Li Y, Weinberg DS. Association of GUCY2C expression in lymph nodes with time to recurrence and diseasefree survival in pN0 colorectal cancer. JAMA. 2009;301: 745-52.
-
(2009)
JAMA
, vol.301
, pp. 745-752
-
-
Waldman, S.A.1
Hyslop, T.2
Schulz, S.3
Barkun, A.4
Nielsen, K.5
Haaf, J.6
Bonaccorso, C.7
Li, Y.8
Weinberg, D.S.9
-
47
-
-
0027933841
-
Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: A phase I trial
-
Wilson JM, Engelhardt JF, Grossman M, Simon RH, Yang Y. Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: A phase I trial. Hum Gene Ther. 1994;5:501-19.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 501-519
-
-
Wilson, J.M.1
Engelhardt, J.F.2
Grossman, M.3
Simon, R.H.4
Yang, Y.5
-
48
-
-
0034023958
-
Gene therapy: A rocky start to the new millennium
-
DOI 10.1016/S1357-4310(99)01666-4
-
Senior K: Gene therapy: A rocky start to the new millennium. Mol Med Today. 2000;6:93. (Pubitemid 30148512)
-
(2000)
Molecular Medicine Today
, vol.6
, Issue.3
, pp. 93
-
-
Senior, K.1
-
49
-
-
34247248864
-
Use of viral vectors for the development of vaccines
-
DOI 10.1586/14760584.6.2.255
-
Liniger M, Zuniga A, Naim HY. Use of viral vectors for the development of vaccines. Expert Rev Vaccin. 2007;6:255-66. (Pubitemid 46613525)
-
(2007)
Expert Review of Vaccines
, vol.6
, Issue.2
, pp. 255-266
-
-
Liniger, M.1
Zuniga, A.2
Naim, H.Y.3
-
50
-
-
0017710978
-
Characteristics of a human cell line transformed by DNA from human adenovirus type 5
-
Graham FL, Smiley J, Russell WC, Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol. 1977;36:59-74.
-
(1977)
J Gen Virol
, vol.36
, pp. 59-74
-
-
Graham, F.L.1
Smiley, J.2
Russell, W.C.3
Nairn, R.4
-
52
-
-
0029616020
-
Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutants
-
Krougliak V, Graham FL. Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutants. Hum Gene Ther. 1995;6:1575-86. (Pubitemid 26014568)
-
(1995)
Human Gene Therapy
, vol.6
, Issue.12
, pp. 1575-1586
-
-
Krougliak, V.1
Graham, F.L.2
-
53
-
-
70349348934
-
A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: Report of the Southwest Oncology Group
-
Yoo GH, Moon J, Leblanc M, Lonardo F, Urba S, Kim H, Hanna E, Tsue T, Valentino J, Ensley J, Wolf G: A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: Report of the Southwest Oncology Group. Arch Otolaryngol Head Neck Surg. 2009;135:869-4.
-
(2009)
Arch Otolaryngol Head Neck Surg
, vol.135
, pp. 869-864
-
-
Yoo, G.H.1
Moon, J.2
Leblanc, M.3
Lonardo, F.4
Urba, S.5
Kim, H.6
Hanna, E.7
Tsue, T.8
Valentino, J.9
Ensley, J.10
Wolf, G.11
-
54
-
-
64149107093
-
Phase I study of repeated intraepithelial delivery of adenoviral p53 in patients with dysplastic oral leukoplakia
-
Zhang S, Li Y, Li L, Zhang Y, Gao N, Zhang Z, Zhao H. Phase I study of repeated intraepithelial delivery of adenoviral p53 in patients with dysplastic oral leukoplakia. J Oral Maxillofac Surg. 2009;67:1074-82.
-
(2009)
J Oral Maxillofac Surg
, vol.67
, pp. 1074-1082
-
-
Zhang, S.1
Li, Y.2
Li, L.3
Zhang, Y.4
Gao, N.5
Zhang, Z.6
Zhao, H.7
-
55
-
-
68949197421
-
Phase I. And biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors
-
Xu F, Li S, Li XL, Guo Y, Zou BY, Xu R, Liao H, Zhao HY, Zhang Y, Guan ZZ, Zhang L. Phase I and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors. Cancer Gene Ther. 2009;16:723-30.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 723-730
-
-
Xu, F.1
Li, S.2
Li, X.L.3
Guo, Y.4
Zou, B.Y.5
Xu, R.6
Liao, H.7
Zhao, H.Y.8
Zhang, Y.9
Guan, Z.Z.10
Zhang, L.11
-
56
-
-
43949099690
-
Safety and immunogenicity of a replication-incompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults
-
DOI 10.1086/587993
-
Priddy FH, Brown D, Kublin J, Monahan K, Wright DP, Lalezari J, Santiago S, Marmor M, Lally M, Novak RM, Brown SJ, Kulkarni P, Dubey SA, Kierstead LS, Casimiro DR, Mogg R, DiNubile MJ, Shiver JW, Leavitt RY, Robertson MN, Mehrotra DV, Quirk E. Safety and immunogenicity of a replicationincompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults. Clin Infect Dis. 2008;46:1769-81. (Pubitemid 351706778)
-
(2008)
Clinical Infectious Diseases
, vol.46
, Issue.11
, pp. 1769-1781
-
-
Priddy, F.H.1
Brown, D.2
Kublin, J.3
Monahan, K.4
Wright, D.P.5
Lalezari, J.6
Santiago, S.7
Marmor, M.8
Lally, M.9
Novak, R.M.10
Brown, S.J.11
Kulkarni, P.12
Dubey, S.A.13
Kierstead, L.S.14
Casimiro, D.R.15
Mogg, R.16
DiNubile, M.J.17
Shiver, J.W.18
Leavitt, R.Y.19
Robertson, M.N.20
Mehrotra, D.V.21
Quirk, E.22
more..
-
57
-
-
33845439080
-
Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector
-
DOI 10.1086/509258
-
Catanzaro AT, Koup RA, Roederer M, Bailer RT, Enama ME, Moodie Z, Gu L, Martin JE, Novik L, Chakrabarti BK, Butman BT, Gall JG, King CR, Andrews CA, Sheets R, Gomez PL, Mascola JR, Nabel GJ, Graham BS. Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector. J Infect Dis. 2006;194:1638-49. (Pubitemid 44901994)
-
(2006)
Journal of Infectious Diseases
, vol.194
, Issue.12
, pp. 1638-1649
-
-
Catanzaro, A.T.1
Koup, R.A.2
Roederer, M.3
Bailer, R.T.4
Enama, M.E.5
Moodie, Z.6
Gu, L.7
Martin, J.E.8
Novik, L.9
Chakrabarti, B.K.10
Butman, B.T.11
Gall, J.G.D.12
King, C.R.13
Andrews, C.A.14
Sheets, R.15
Gomez, P.L.16
Mascola, J.R.17
Nabel, G.J.18
Graham, B.S.19
Larkin, B.20
McCluskey, M.21
Hubka, S.22
Holman, L.23
Gordon, I.24
Edmonds, P.25
Rucker, S.26
Parrino, J.27
Casazza, J.28
Fix, A.29
more..
-
58
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, Li D, Gilbert PB, Lama JR, Marmor M, Del Rio C, McElrath MJ, Casimiro DR, Gottesdiener KM, Chodakewitz JA, Corey L, Robertson MN. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet. 2008;372:1881-93.
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
Fitzgerald, D.W.4
Mogg, R.5
Li, D.6
Gilbert, P.B.7
Lama, J.R.8
Marmor, M.9
Del Rio, C.10
McElrath, M.J.11
Casimiro, D.R.12
Gottesdiener, K.M.13
Chodakewitz, J.A.14
Corey, L.15
Robertson, M.N.16
-
59
-
-
46849089908
-
Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity
-
DOI 10.1093/jnci/djn178
-
Snook AE, Stafford BJ, Li P, Tan G, Huang L, Birbe R, Schulz S, Schnell MJ, Thakur M, Rothstein JL, Eisenlohr LC, Waldman SA. Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity. J Natl Cancer Inst. 2008;100:950-61. (Pubitemid 351957514)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.13
, pp. 950-961
-
-
Snook, A.E.1
Stafford, B.J.2
Li, P.3
Tan, G.4
Huang, L.5
Birbe, R.6
Schulz, S.7
Schnell, M.J.8
Thakur, M.9
Rothstein, J.L.10
Eisenlohr, L.C.11
Waldman, S.A.12
-
60
-
-
65949089637
-
Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease
-
Snook AE, Li P, Stafford BJ, Faul EJ, Huang L, Birbe RC, Bombonati A, Schulz S, Schnell MJ, Eisenlohr LC, Waldman SA. Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease. Cancer Res. 2009;69:3537-44.
-
(2009)
Cancer Res
, vol.69
, pp. 3537-3544
-
-
Snook, A.E.1
Li, P.2
Stafford, B.J.3
Faul, E.J.4
Huang, L.5
Birbe, R.C.6
Bombonati, A.7
Schulz, S.8
Schnell, M.J.9
Eisenlohr, L.C.10
Waldman, S.A.11
-
61
-
-
77953465549
-
Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens
-
Snook AE, Huang L, Schulz S, Eisenlohr LC, Waldman SA. Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens. Clin Trans Sci. 2008;1:263-4.
-
(2008)
Clin Trans Sci
, vol.1
, pp. 263-264
-
-
Snook, A.E.1
Huang, L.2
Schulz, S.3
Eisenlohr, L.C.4
Waldman, S.A.5
-
62
-
-
33744815600
-
Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer
-
DOI 10.1158/1078-0432.CCR-05-2788
-
Nagorsen D, Thiel E. Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer. Clin Cancer Res. 2006;12:3064-9. (Pubitemid 43837352)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.10
, pp. 3064-3069
-
-
Nagorsen, D.1
Thiel, E.2
-
64
-
-
22144433725
-
Towards therapeutic vaccines for colorectal carcinoma: A review of clinical trials
-
DOI 10.1586/14760584.4.3.329
-
Mosolits S, Nilsson B, Mellstedt H. Towards therapeutic vaccines for colorectal carcinoma: A review of clinical trials. Expert Rev Vaccines. 2005;4:329-50. (Pubitemid 40978696)
-
(2005)
Expert Review of Vaccines
, vol.4
, Issue.3
, pp. 329-350
-
-
Mosolits, S.1
Nilsson, B.2
Mellstedt, H.3
-
67
-
-
0003809054
-
AJCC cancer staging manual
-
Springer
-
Greene FL. AJCC cancer staging manual. New York: Springer; 2002.
-
(2002)
New York
-
-
Greene, F.L.1
-
68
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
DOI 10.1038/nm1100
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: Moving beyond current vaccines. Nat Med. 2004;10:909-15. (Pubitemid 39273730)
-
(2004)
Nature Medicine
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
69
-
-
80053567512
-
Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know
-
Rosenberg SA: Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know. Nat Rev Clin Oncol 2011.
-
Nat Rev Clin Oncol 2011
-
-
Rosenberg, S.A.1
-
70
-
-
65249173447
-
Adoptive cell therapy for the treatment of patients with metastatic melanoma
-
Rosenberg SA, Dudley ME. Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr Opin Immunol. 2009;21:233-40.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 233-240
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
71
-
-
77957981209
-
Adoptive cell therapy: Genetic modification to redirect effector cell specificity
-
Morgan RA, Dudley ME, Rosenberg SA. Adoptive cell therapy: Genetic modification to redirect effector cell specificity. Cancer J. 2010;16:336-41.
-
(2010)
Cancer J
, vol.16
, pp. 336-341
-
-
Morgan, R.A.1
Dudley, M.E.2
Rosenberg, S.A.3
-
72
-
-
0029608719
-
Targeting p53 as a general tumor antigen
-
DOI 10.1073/pnas.92.26.11993
-
Theobald M, Biggs J, Dittmer D, Levine AJ, Sherman LA. Targeting p53 as a general tumor antigen. Proc Natl Acad Sci USA. 1995;92:11993-7. (Pubitemid 26013997)
-
(1995)
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, Issue.26
, pp. 11993-11997
-
-
Theobald, M.1
Biggs, J.2
Dittmer, D.3
Levine, A.J.4
Sherman, L.A.5
-
73
-
-
58849160937
-
Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells
-
Parkhurst MR, Joo J, Riley JP, Yu Z, Li Y, Robbins PF, Rosenberg SA. Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells. Clin Cancer Res. 2009;15:169-80.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 169-180
-
-
Parkhurst, M.R.1
Joo, J.2
Riley, J.P.3
Yu, Z.4
Li, Y.5
Robbins, P.F.6
Rosenberg, S.A.7
-
74
-
-
33646804507
-
Mechanisms of immune evasion by tumors
-
DOI 10.1016/S0065-2776(06)90002-9, PII S0065277606900029
-
Drake CG, Jaffee E, Pardoll DM. Mechanisms of immune evasion by tumors. Adv Immunol. 2006;90:51-81. (Pubitemid 43765799)
-
(2006)
Advances in Immunology
, vol.90
, pp. 51-81
-
-
Drake, C.G.1
Jaffee, E.2
Pardoll, D.M.3
-
75
-
-
0027471898
-
Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the γ or ζsubunits of the immunoglobulin and T-cell receptors
-
DOI 10.1073/pnas.90.2.720
-
Eshhar Z, Waks T, Gross G, Schindler DG. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors. Proc Natl Acad Sci USA. 1993;90:720-4. (Pubitemid 23028937)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.2
, pp. 720-724
-
-
Eshhar, Z.1
Waks, T.2
Gross, G.3
Schindler, D.G.4
-
76
-
-
77950961198
-
Building better chimeric antigen receptors for adoptive T cell therapy
-
Bridgeman JS, Hawkins RE, Hombach AA, Abken H, Gilham DE. Building better chimeric antigen receptors for adoptive T cell therapy. Curr Gene Ther. 2010;10:77-90.
-
(2010)
Curr Gene Ther
, vol.10
, pp. 77-90
-
-
Bridgeman, J.S.1
Hawkins, R.E.2
Hombach, A.A.3
Abken, H.4
Gilham, D.E.5
-
77
-
-
20944439742
-
The role of extracellular spacer regions in the optimal design of chimeric immune receptors: Evaluation of four different scFvs and antigens
-
Guest RD, Hawkins RE, Kirillova N, Cheadle EJ, Arnold J, O'Neill A, Irlam J, Chester KA, Kemshead JT, Shaw DM, Embleton MJ, Stern PL, Gilham DE. The role of extracellular spacer regions in the optimal design of chimeric immune receptors: Evaluation of four different scFvs and antigens. J Immunother. 2005;28:203-11. (Pubitemid 40593985)
-
(2005)
Journal of Immunotherapy
, vol.28
, Issue.3
, pp. 203-211
-
-
Guest, R.D.1
Hawkins, R.E.2
Kirillova, N.3
Cheadle, E.J.4
Arnold, J.5
O'Neill, A.6
Irlam, J.7
Chester, K.A.8
Kemshead, J.T.9
Shaw, D.M.10
Embleton, M.J.11
Stern, P.L.12
Gilham, D.E.13
-
78
-
-
44449162630
-
Retargeting of human T cells to tumor-associated MUC1: The evolution of a chimeric antigen receptor
-
Wilkie S, Picco G, Foster J, Davies DM, Julien S, Cooper L, Arif S, Mather SJ, Taylor-Papadimitriou J, Burchell JM, Maher J. Retargeting of human T cells to tumor-associated MUC1: The evolution of a chimeric antigen receptor. J Immunol. 2008;180: 4901-9.
-
(2008)
J Immunol
, vol.180
, pp. 4901-4909
-
-
Wilkie, S.1
Picco, G.2
Foster, J.3
Davies, D.M.4
Julien, S.5
Cooper, L.6
Arif, S.7
Mather, S.J.8
Taylor-Papadimitriou, J.9
Burchell, J.M.10
Maher, J.11
-
79
-
-
58149331194
-
Second-generation anti-carcinoembryonic antigen designer T cells resist activation-induced cell death, proliferate on tumor contact, secrete cytokines, and exhibit superior antitumor activity in vivo: A preclinical evaluation
-
Emtage PC, Lo AS, Gomes EM, Liu DL, Gonzalo-Daganzo RM, Junghans RP. Second-generation anti-carcinoembryonic antigen designer T cells resist activation-induced cell death, proliferate on tumor contact, secrete cytokines, and exhibit superior antitumor activity in vivo: A preclinical evaluation. Clin Cancer Res. 2008;14:8112-22.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8112-8122
-
-
Emtage, P.C.1
Lo, A.S.2
Gomes, E.M.3
Liu, D.L.4
Gonzalo-Daganzo, R.M.5
Junghans, R.P.6
-
80
-
-
0347994955
-
Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain
-
Finney HM, Akbar AN, Lawson AD. Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain. J Immunol. 2004;172:104-13. (Pubitemid 38020461)
-
(2004)
Journal of Immunology
, vol.172
, Issue.1
, pp. 104-113
-
-
Finney, H.M.1
Akbar, A.N.2
Lawson, A.D.G.3
-
81
-
-
77957756405
-
Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells
-
Kochenderfer JN, Yu Z, Frasheri D, Restifo NP, Rosenberg SA: Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood. 2010.
-
(2010)
Blood
-
-
Kochenderfer, J.N.1
Yu, Z.2
Frasheri, D.3
Restifo, N.P.4
Rosenberg, S.A.5
-
82
-
-
78549278144
-
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically-engineered to recognize CD19
-
Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler- Stevenson M, Feldman SA, Maric I, Raffeld M, Nathan DA, Lanier BJ, Morgan RA, Rosenberg SA: Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically-engineered to recognize CD19. Blood. 2010.
-
(2010)
Blood
-
-
Kochenderfer, J.N.1
Wilson, W.H.2
Janik, J.E.3
Dudley, M.E.4
Stetler-Stevenson, M.5
Feldman, S.A.6
Maric, I.7
Raffeld, M.8
Nathan, D.A.9
Lanier, B.J.10
Morgan, R.A.11
Rosenberg, S.A.12
-
83
-
-
84856524751
-
-
Song D, Ye Q, Carpenito C, Poussin M, Wang LP, Ji C, Figini M, June CH, Coukos G, Sr., Powell DJ, Jr.: Improved T cell survival provided by CD137 costimulatory signaling to folate receptor- redirected T cells results in tumor localization and eradication. Cancer Res. 2011.
-
(2011)
Jr.: Improved T cell survival provided by CD137 costimulatory signaling to folate receptor- redirected T cells results in tumor localization and eradication. Cancer Res
-
-
Song, D.1
Ye, Q.2
Carpenito, C.3
Poussin, M.4
Wang, L.P.5
Ji, C.6
Figini, M.7
June, C.H.8
Coukos Sr., G.9
Powell, D.J.10
-
85
-
-
62549097817
-
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
-
Carpenito C, Milone MC, Hassan R, Simonet JC, Lakhal M, Suhoski MM, Varela-Rohena A, Haines KM, Heitjan DF, Albelda SM, Carroll RG, Riley JL, Pastan I, June CH. Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. Proc Natl Acad Sci USA. 2009;106:3360-5.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3360-3365
-
-
Carpenito, C.1
Milone, M.C.2
Hassan, R.3
Simonet, J.C.4
Lakhal, M.5
Suhoski, M.M.6
Varela-Rohena, A.7
Haines, K.M.8
Heitjan, D.F.9
Albelda, S.M.10
Carroll, R.G.11
Riley, J.L.12
Pastan, I.13
June, C.H.14
-
86
-
-
27744566329
-
A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells
-
DOI 10.1016/j.ymthe.2005.04.016, PII S1525001605001863
-
Pule MA, Straathof KC, Dotti G, Heslop HE, Rooney CM, Brenner MK. A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells. Mol Ther. 2005;12:933-41. (Pubitemid 41614489)
-
(2005)
Molecular Therapy
, vol.12
, Issue.5
, pp. 933-941
-
-
Pule, M.A.1
Straathof, K.C.2
Dotti, G.3
Heslop, H.E.4
Rooney, C.M.5
Brenner, M.K.6
-
87
-
-
79955517235
-
CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
-
Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, Kamble RT, Bollard CM, Gee AP, Mei Z, Liu H, Grilley B, Rooney CM, Heslop HE, Brenner MK, Dotti G: CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest. 2011.
-
(2011)
J Clin Invest
-
-
Savoldo, B.1
Ramos, C.A.2
Liu, E.3
Mims, M.P.4
Keating, M.J.5
Carrum, G.6
Kamble, R.T.7
Bollard, C.M.8
Gee, A.P.9
Mei, Z.10
Liu, H.11
Grilley, B.12
Rooney, C.M.13
Heslop, H.E.14
Brenner, M.K.15
Dotti, G.16
-
88
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos M, Levine BL, Porter DL, Katz S, Grupp SA, Bagg A, June CH: T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med. 2011;3:95ra73.
-
(2011)
Sci Transl Med
, vol.3
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
June, C.H.7
-
89
-
-
83055168476
-
Chimeric antigen receptor therapy for B-cell malignancies
-
Porter DL, Kalos M, Zheng Z, Levine B, June C. Chimeric antigen receptor therapy for B-cell malignancies. J Cancer. 2011;2:331-2.
-
(2011)
J Cancer
, vol.2
, pp. 331-332
-
-
Porter, D.L.1
Kalos, M.2
Zheng, Z.3
Levine, B.4
June, C.5
-
90
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
DOI 10.1126/science.1076514
-
Dudley ME, Wunderlich JR, Robbins PF, Yang JC, Hwu P, Schwartzentruber DJ, Topalian SL, Sherry R, Restifo NP, Hubicki AM, Robinson MR, Raffeld M, Duray P, Seipp CA, Rogers-Freezer L, Morton KE, Mavroukakis SA, White DE, Rosenberg SA. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science. 2002;298:850-4. (Pubitemid 35231542)
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 850-854
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Robbins, P.F.3
Yang, J.C.4
Hwu, P.5
Schwartzentruber, D.J.6
Topalian, S.L.7
Sherry, R.8
Restifo, N.P.9
Hubicki, A.M.10
Robinson, M.R.11
Raffeld, M.12
Duray, P.13
Seipp, C.A.14
Rogers-Freezer, L.15
Morton, K.E.16
Mavroukakis, S.A.17
White, D.E.18
Rosenberg, S.A.19
-
91
-
-
33646440024
-
Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
-
Lamers CH, Sleijfer S, Vulto AG, Kruit WH, Kliffen M, Debets R, Gratama JW, Stoter G, Oosterwijk E. Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience. J Clin Oncol. 2006;24:e20-2.
-
(2006)
J Clin Oncol
, vol.24
-
-
Lamers, C.H.1
Sleijfer, S.2
Vulto, A.G.3
Kruit, W.H.4
Kliffen, M.5
Debets, R.6
Gratama, J.W.7
Stoter, G.8
Oosterwijk, E.9
-
92
-
-
54249148553
-
Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen
-
Bos R, van Duikeren S, Morreau H, Franken K, Schumacher TN, Haanen JB, van der Burg SH, Melief CJ, Offringa R. Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen. Cancer Res. 2008;68:8446-55.
-
(2008)
Cancer Res
, vol.68
, pp. 8446-8455
-
-
Bos, R.1
Van Duikeren, S.2
Morreau, H.3
Franken, K.4
Schumacher, T.N.5
Haanen, J.B.6
Van Der Burg, S.H.7
Melief, C.J.8
Offringa, R.9
-
93
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther. 2010;18:843-51.
-
(2010)
Mol Ther
, vol.18
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
Dudley, M.E.4
Laurencot, C.M.5
Rosenberg, S.A.6
-
94
-
-
79955512733
-
Considerations for the clinical application of chimeric antigen receptor T cells: Observations from a recombinant DNA advisory committee symposium held June 15 2010
-
Ertl HC, Zaia J, Rosenberg SA, June CH, Dotti G, Kahn J, Cooper LJ, Corrigan-Curay J, Strome SE. Considerations for the clinical application of chimeric antigen receptor T cells: Observations from a recombinant DNA advisory committee symposium held, June 15, 2010. Cancer Res. 2011;71:3175-81.
-
(2011)
Cancer Res
, vol.71
, pp. 3175-3181
-
-
Ertl, H.C.1
Zaia, J.2
Rosenberg, S.A.3
June, C.H.4
Dotti, G.5
Kahn, J.6
Cooper, L.J.7
Corrigan-Curay, J.8
Strome, S.E.9
-
95
-
-
77955510549
-
Anti-transgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor re-directed T cells in humans
-
Jensen MC, Popplewell L, Cooper LJ, Digiusto D, Kalos M, Ostberg JR, Forman SJ: Anti-transgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor re-directed T cells in humans. Biol Blood Marrow Transplant. 2010.
-
(2010)
Biol Blood Marrow Transplant
-
-
Jensen, M.C.1
Popplewell, L.2
Cooper, L.J.3
Digiusto, D.4
Kalos, M.5
Ostberg, J.R.6
Forman, S.J.7
-
96
-
-
35549007239
-
Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes
-
DOI 10.1182/blood-2007-02-072843
-
Quintarelli C, Vera JF, Savoldo B, Giordano Attianese GM, Pule M, Foster AE, Heslop HE, Rooney CM, Brenner MK, Dotti G. Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood. 2007;110:2793-802. (Pubitemid 350006931)
-
(2007)
Blood
, vol.110
, Issue.8
, pp. 2793-2802
-
-
Quintarelli, C.1
Vera, J.F.2
Savoldo, B.3
Attianese, G.M.P.G.4
Pule, M.5
Foster, A.E.6
Heslop, H.E.7
Rooney, C.M.8
Brenner, M.K.9
Dotti, G.10
-
97
-
-
36148966955
-
Cancer mucosa antigens as a novel immunotherapeutic class of tumor-associated antigen
-
DOI 10.1038/sj.clpt.6100369, PII 6100369
-
Snook AE, Eisenlohr LC, Rothstein JL, Waldman SA. Cancer mucosa antigens as a novel immunotherapeutic class of tumorassociated antigen. Clin Pharmacol Ther. 2007;82:734-9. (Pubitemid 350114818)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.82
, Issue.6
, pp. 734-739
-
-
Snook, A.E.1
Eisenlohr, L.C.2
Rothstein, J.L.3
Waldman, S.A.4
-
98
-
-
0036971525
-
Guanylin and functional coupling proteins in the human salivary glands and gland tumors: Expression, cellular localization, and target membrane domains
-
Kulaksiz H, Rehberg E, Stremmel W, Cetin Y. Guanylin and functional coupling proteins in the human salivary glands and gland tumors: Expression, cellular localization, and target membrane domains. Am J Pathol. 2002;161:655-64. (Pubitemid 36142174)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.2
, pp. 655-664
-
-
Kulaksiz, H.1
Rehberg, E.2
Stremmel, W.3
Cetin, Y.4
-
99
-
-
80052362732
-
A uroguanylin-GUCY2C endocrine axis regulates feeding in mice
-
Valentino MA, Lin JE, Snook AE, Li P, Kim GW, Marszalowicz G, Magee MS, Hyslop T, Schulz S, Waldman SA: A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. J Clin Invest. 2011.
-
(2011)
J Clin Invest
-
-
Valentino, M.A.1
Lin, J.E.2
Snook, A.E.3
Li, P.4
Kim, G.W.5
Marszalowicz, G.6
Magee, M.S.7
Hyslop, T.8
Schulz, S.9
Waldman, S.A.10
-
100
-
-
79953325686
-
Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment
-
Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, Rosenberg SA, Morgan RA. Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Mol Ther. 2011;19:751-9.
-
(2011)
Mol Ther
, vol.19
, pp. 751-759
-
-
Zhang, L.1
Kerkar, S.P.2
Yu, Z.3
Zheng, Z.4
Yang, S.5
Restifo, N.P.6
Rosenberg, S.A.7
Morgan, R.A.8
-
101
-
-
84856533535
-
IL-12 release by macrophages expressing chimeric antigen receptors can effectively restore T cell attacks on tumor cells that have shut down tumor antigen expression
-
Chmielewski M, Kopecky C, Hombach A, Abken H: IL-12 release by macrophages expressing chimeric antigen receptors can effectively restore T cell attacks on tumor cells that have shut down tumor antigen expression. Cancer Res. 2011.
-
(2011)
Cancer Res
-
-
Chmielewski, M.1
Kopecky, C.2
Hombach, A.3
Abken, H.4
|