메뉴 건너뛰기




Volumn 142, Issue 2, 2012, Pages 167-175

Noncollagenous 16A domain of type XVII collagen-reactive CD4 + T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model

Author keywords

Autoimmune disease; ; Autoreactive T cells; ; CD40 ligand; ; Pathomechanism

Indexed keywords

COLLAGEN ANTIBODY; COLLAGEN TYPE 17; COLLAGEN TYPE 17 ANTIBODY; EPITOPE; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

EID: 84856522358     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2011.10.002     Document Type: Article
Times cited : (22)

References (37)
  • 1
    • 0025053990 scopus 로고
    • Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome
    • Diaz L.A., Ratrie H., Saunders W.S., Futamura S., Squiquera H.L., Anhalt G.J., et al. Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome. J. Clin. Invest. 1990, 86:1088-1094.
    • (1990) J. Clin. Invest. , vol.86 , pp. 1088-1094
    • Diaz, L.A.1    Ratrie, H.2    Saunders, W.S.3    Futamura, S.4    Squiquera, H.L.5    Anhalt, G.J.6
  • 2
    • 0026726355 scopus 로고
    • Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
    • Giudice G.J., Emery D.J., Diaz L.A. Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180. J. Invest. Dermatol. 1992, 99:243-250.
    • (1992) J. Invest. Dermatol. , vol.99 , pp. 243-250
    • Giudice, G.J.1    Emery, D.J.2    Diaz, L.A.3
  • 3
    • 0026730506 scopus 로고
    • Cytoplasmic domain of the 180-kD bullous pemphigoid antigen, a hemidesmosomal component: molecular and cell biologic characterization
    • Hopkinson S.B., Riddelle K.S., Jones J.C. Cytoplasmic domain of the 180-kD bullous pemphigoid antigen, a hemidesmosomal component: molecular and cell biologic characterization. J. Invest. Dermatol. 1992, 99:264-270.
    • (1992) J. Invest. Dermatol. , vol.99 , pp. 264-270
    • Hopkinson, S.B.1    Riddelle, K.S.2    Jones, J.C.3
  • 4
    • 0027255972 scopus 로고
    • Human autoantibodies against the 230-kD bullous pemphigoid antigen (BPAG1) bind only to the intracellular domain of the hemidesmosome, whereas those against the 180-kD bullous pemphigoid antigen (BPAG2) bind along the plasma membrane of the hemidesmosome in normal human and swine skin
    • Ishiko A., Shimizu H., Kikuchi A., Ebihara T., Hashimoto T., Nishikawa T. Human autoantibodies against the 230-kD bullous pemphigoid antigen (BPAG1) bind only to the intracellular domain of the hemidesmosome, whereas those against the 180-kD bullous pemphigoid antigen (BPAG2) bind along the plasma membrane of the hemidesmosome in normal human and swine skin. J. Clin. Invest. 1993, 91:1608-1615.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1608-1615
    • Ishiko, A.1    Shimizu, H.2    Kikuchi, A.3    Ebihara, T.4    Hashimoto, T.5    Nishikawa, T.6
  • 5
    • 0030908421 scopus 로고    scopus 로고
    • Bullous pemphigoid and cicatricial pemphigoid autoantibodies react with ultrastructurally separable epitopes on the BP180 ectodomain: evidence that BP180 spans the lamina lucida
    • Bedane C., McMillan J.R., Balding S.D., Bernard P., Prost C., Bonnetblanc J.M., et al. Bullous pemphigoid and cicatricial pemphigoid autoantibodies react with ultrastructurally separable epitopes on the BP180 ectodomain: evidence that BP180 spans the lamina lucida. J. Invest. Dermatol. 1997, 108:901-907.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 901-907
    • Bedane, C.1    McMillan, J.R.2    Balding, S.D.3    Bernard, P.4    Prost, C.5    Bonnetblanc, J.M.6
  • 6
    • 0037406396 scopus 로고    scopus 로고
    • Epidermal basement membrane zone components: ultrastructural distribution and molecular interactions
    • McMillan J.R., Akiyama M., Shimizu H. Epidermal basement membrane zone components: ultrastructural distribution and molecular interactions. J. Dermatol. Sci. 2003, 31:169-177.
    • (2003) J. Dermatol. Sci. , vol.31 , pp. 169-177
    • McMillan, J.R.1    Akiyama, M.2    Shimizu, H.3
  • 7
    • 0027487314 scopus 로고
    • Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain
    • Giudice G.J., Emery D.J., Zelickson B.D., Anhalt G.J., Liu Z., Diaz L.A. Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain. J. Immunol. 1993, 151:5742-5750.
    • (1993) J. Immunol. , vol.151 , pp. 5742-5750
    • Giudice, G.J.1    Emery, D.J.2    Zelickson, B.D.3    Anhalt, G.J.4    Liu, Z.5    Diaz, L.A.6
  • 8
    • 0030879947 scopus 로고    scopus 로고
    • Tight clustering of extracellular BP180 epitopes recognized by bullous pemphigoid autoantibodies
    • Zillikens D., Rose P.A., Balding S.D., Liu Z., Olague-Marchan M., Diaz L.A., et al. Tight clustering of extracellular BP180 epitopes recognized by bullous pemphigoid autoantibodies. J. Invest. Dermatol. 1997, 109:573-579.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 573-579
    • Zillikens, D.1    Rose, P.A.2    Balding, S.D.3    Liu, Z.4    Olague-Marchan, M.5    Diaz, L.A.6
  • 9
    • 14744301980 scopus 로고    scopus 로고
    • Correlation of clinical severity and ELISA indices for the NC16A domain of BP180 measured using BP180 ELISA kit in bullous pemphigoid
    • Tsuji-Abe Y., Akiyama M., Yamanaka Y., Kikuchi T., Sato-Matsumura K.C., Shimizu H. Correlation of clinical severity and ELISA indices for the NC16A domain of BP180 measured using BP180 ELISA kit in bullous pemphigoid. J. Dermatol. Sci. 2005, 37:145-149.
    • (2005) J. Dermatol. Sci. , vol.37 , pp. 145-149
    • Tsuji-Abe, Y.1    Akiyama, M.2    Yamanaka, Y.3    Kikuchi, T.4    Sato-Matsumura, K.C.5    Shimizu, H.6
  • 10
    • 77949889249 scopus 로고    scopus 로고
    • A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen
    • Ujiie H., Shibaki A., Nishie W., Sawamura D., Wang G., Tateishi Y., et al. A novel active mouse model for bullous pemphigoid targeting humanized pathogenic antigen. J. Immunol. 2010, 184:2166-2174.
    • (2010) J. Immunol. , vol.184 , pp. 2166-2174
    • Ujiie, H.1    Shibaki, A.2    Nishie, W.3    Sawamura, D.4    Wang, G.5    Tateishi, Y.6
  • 11
    • 0032535445 scopus 로고    scopus 로고
    • Identification and characterization of autoreactive T cell responses to bullous pemphigoid antigen 2 in patients and healthy controls
    • Budinger L., Borradori L., Yee C., Eming R., Ferencik S., Grosse-Wilde H., et al. Identification and characterization of autoreactive T cell responses to bullous pemphigoid antigen 2 in patients and healthy controls. J. Clin. Invest. 1998, 102:2082-2089.
    • (1998) J. Clin. Invest. , vol.102 , pp. 2082-2089
    • Budinger, L.1    Borradori, L.2    Yee, C.3    Eming, R.4    Ferencik, S.5    Grosse-Wilde, H.6
  • 12
    • 0034519016 scopus 로고    scopus 로고
    • Epitopes targeted by bullous pemphigoid T lymphocytes and autoantibodies map to the same sites on the bullous pemphigoid 180 ectodomain
    • Lin M.S., Fu C.L., Giudice G.J., Olague-Marchan M., Lazaro A.M., Stastny P., et al. Epitopes targeted by bullous pemphigoid T lymphocytes and autoantibodies map to the same sites on the bullous pemphigoid 180 ectodomain. J. Invest. Dermatol. 2000, 115:955-961.
    • (2000) J. Invest. Dermatol. , vol.115 , pp. 955-961
    • Lin, M.S.1    Fu, C.L.2    Giudice, G.J.3    Olague-Marchan, M.4    Lazaro, A.M.5    Stastny, P.6
  • 13
    • 31144466804 scopus 로고    scopus 로고
    • Autoreactive T and B cells from bullous pemphigoid (BP) patients recognize epitopes clustered in distinct regions of BP180 and BP230
    • Thoma-Uszynski S., Uter W., Schwietzke S., Schuler G., Borradori L., Hertl M. Autoreactive T and B cells from bullous pemphigoid (BP) patients recognize epitopes clustered in distinct regions of BP180 and BP230. J. Immunol. 2006, 176:2015-2023.
    • (2006) J. Immunol. , vol.176 , pp. 2015-2023
    • Thoma-Uszynski, S.1    Uter, W.2    Schwietzke, S.3    Schuler, G.4    Borradori, L.5    Hertl, M.6
  • 14
    • 9444242640 scopus 로고    scopus 로고
    • A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid
    • Delgado J.C., Turbay D., Yunis E.J., Yunis J.J., Morton E.D., Bhol K., et al. A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:8569-8571.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 8569-8571
    • Delgado, J.C.1    Turbay, D.2    Yunis, E.J.3    Yunis, J.J.4    Morton, E.D.5    Bhol, K.6
  • 15
    • 3242762566 scopus 로고    scopus 로고
    • A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice
    • Aoki-Ota M., Tsunoda K., Ota T., Iwasaki T., Koyasu S., Amagai M., et al. A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice. Br. J. Dermatol. 2004, 151:346-354.
    • (2004) Br. J. Dermatol. , vol.151 , pp. 346-354
    • Aoki-Ota, M.1    Tsunoda, K.2    Ota, T.3    Iwasaki, T.4    Koyasu, S.5    Amagai, M.6
  • 16
    • 77949327289 scopus 로고    scopus 로고
    • T cells are required for the production of blister-inducing autoantibodies in experimental epidermolysis bullosa acquisita
    • Sitaru A.G., Sesarman A., Mihai S., Chiriac M.T., Zillikens D., Hultman P., et al. T cells are required for the production of blister-inducing autoantibodies in experimental epidermolysis bullosa acquisita. J. Immunol. 2010, 184:1596-1603.
    • (2010) J. Immunol. , vol.184 , pp. 1596-1603
    • Sitaru, A.G.1    Sesarman, A.2    Mihai, S.3    Chiriac, M.T.4    Zillikens, D.5    Hultman, P.6
  • 18
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle R.J., Roy M., Shepherd D.M., Stamenkovic I., Ledbetter J.A., Aruffo A. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl. Acad. Sci. U.S.A. 1992, 89:6550-6554.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 6550-6554
    • Noelle, R.J.1    Roy, M.2    Shepherd, D.M.3    Stamenkovic, I.4    Ledbetter, J.A.5    Aruffo, A.6
  • 19
    • 70349151322 scopus 로고    scopus 로고
    • CD40 and autoimmunity: the dark side of a great activator
    • Peters A.L., Stunz L.L., Bishop G.A. CD40 and autoimmunity: the dark side of a great activator. Semin. Immunol. 2009, 21:293-300.
    • (2009) Semin. Immunol. , vol.21 , pp. 293-300
    • Peters, A.L.1    Stunz, L.L.2    Bishop, G.A.3
  • 20
    • 0035338676 scopus 로고    scopus 로고
    • Blockade of CD40 ligand suppresses chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4
    • Im S.H., Barchan D., Maiti P.K., Fuchs S., Souroujon M.C. Blockade of CD40 ligand suppresses chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4. J. Immunol. 2001, 166:6893-6898.
    • (2001) J. Immunol. , vol.166 , pp. 6893-6898
    • Im, S.H.1    Barchan, D.2    Maiti, P.K.3    Fuchs, S.4    Souroujon, M.C.5
  • 21
    • 33644770230 scopus 로고    scopus 로고
    • Tolerance induction by the blockade of CD40/CD154 interaction in pemphigus vulgaris mouse model
    • Aoki-Ota M., Kinoshita M., Ota T., Tsunoda K., Iwasaki T., Tanaka S., et al. Tolerance induction by the blockade of CD40/CD154 interaction in pemphigus vulgaris mouse model. J. Invest. Dermatol. 2006, 126:105-113.
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 105-113
    • Aoki-Ota, M.1    Kinoshita, M.2    Ota, T.3    Tsunoda, K.4    Iwasaki, T.5    Tanaka, S.6
  • 22
    • 0037378497 scopus 로고    scopus 로고
    • Suppression of the immune response against exogenous desmoglein 3 in desmoglein 3 knockout mice: an implication for gene therapy
    • Ohyama M., Ota T., Aoki M., Tsunoda K., Harada R., Koyasu S., et al. Suppression of the immune response against exogenous desmoglein 3 in desmoglein 3 knockout mice: an implication for gene therapy. J. Invest. Dermatol. 2003, 120:610-615.
    • (2003) J. Invest. Dermatol. , vol.120 , pp. 610-615
    • Ohyama, M.1    Ota, T.2    Aoki, M.3    Tsunoda, K.4    Harada, R.5    Koyasu, S.6
  • 23
    • 36248972519 scopus 로고    scopus 로고
    • Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice
    • Olasz E.B., Roh J., Yee C.L., Arita K., Akiyama M., Shimizu H., et al. Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice. J. Invest. Dermatol. 2007, 127:2807-2817.
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 2807-2817
    • Olasz, E.B.1    Roh, J.2    Yee, C.L.3    Arita, K.4    Akiyama, M.5    Shimizu, H.6
  • 24
    • 0034116198 scopus 로고    scopus 로고
    • Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus
    • Amagai M., Tsunoda K., Suzuki H., Nishifuji K., Koyasu S., Nishikawa T. Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus. J. Clin. Invest. 2000, 105:625-631.
    • (2000) J. Clin. Invest. , vol.105 , pp. 625-631
    • Amagai, M.1    Tsunoda, K.2    Suzuki, H.3    Nishifuji, K.4    Koyasu, S.5    Nishikawa, T.6
  • 25
    • 20144387101 scopus 로고    scopus 로고
    • Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen
    • Sitaru C., Mihai S., Otto C., Chiriac M.T., Hausser I., Dotterweich B., et al. Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen. J. Clin. Invest. 2005, 115:870-878.
    • (2005) J. Clin. Invest. , vol.115 , pp. 870-878
    • Sitaru, C.1    Mihai, S.2    Otto, C.3    Chiriac, M.T.4    Hausser, I.5    Dotterweich, B.6
  • 26
    • 65049084893 scopus 로고    scopus 로고
    • Transient anti-CD40L co-stimulation blockade prevents immune responses against human bullous pemphigoid antigen 2: implications for gene therapy
    • Lanschuetzer C.M., Olasz E.B., Lazarova Z., Yancey K.B. Transient anti-CD40L co-stimulation blockade prevents immune responses against human bullous pemphigoid antigen 2: implications for gene therapy. J. Invest. Dermatol. 2009, 129:1203-1207.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1203-1207
    • Lanschuetzer, C.M.1    Olasz, E.B.2    Lazarova, Z.3    Yancey, K.B.4
  • 27
    • 0032953939 scopus 로고    scopus 로고
    • Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis
    • Howard L.M., Miga A.J., Vanderlugt C.L., Dal Canto M.C., Laman J.D., Noelle R.J., et al. Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J. Clin. Invest. 1999, 103:281-290.
    • (1999) J. Clin. Invest. , vol.103 , pp. 281-290
    • Howard, L.M.1    Miga, A.J.2    Vanderlugt, C.L.3    Dal Canto, M.C.4    Laman, J.D.5    Noelle, R.J.6
  • 28
    • 0032030667 scopus 로고    scopus 로고
    • Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function
    • Kalled S.L., Cutler A.H., Datta S.K., Thomas D.W. Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function. J. Immunol. 1998, 160:2158-2165.
    • (1998) J. Immunol. , vol.160 , pp. 2158-2165
    • Kalled, S.L.1    Cutler, A.H.2    Datta, S.K.3    Thomas, D.W.4
  • 29
    • 0141453661 scopus 로고    scopus 로고
    • Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis
    • Quezada S.A., Eckert M., Adeyi O.A., Schned A.R., Noelle R.J., Burns C.M. Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis. Arthritis Rheum. 2003, 48:2541-2554.
    • (2003) Arthritis Rheum. , vol.48 , pp. 2541-2554
    • Quezada, S.A.1    Eckert, M.2    Adeyi, O.A.3    Schned, A.R.4    Noelle, R.J.5    Burns, C.M.6
  • 30
    • 9144233481 scopus 로고    scopus 로고
    • Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients
    • Di Zenzo G., Grosso F., Terracina M., Mariotti F., De Pita O., Owaribe K., et al. Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients. J. Invest. Dermatol. 2004, 122:103-110.
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 103-110
    • Di Zenzo, G.1    Grosso, F.2    Terracina, M.3    Mariotti, F.4    De Pita, O.5    Owaribe, K.6
  • 32
    • 80054767012 scopus 로고    scopus 로고
    • Demonstration of epitope-spreading phenomena in bullous pemphigoid: results of a prospective multicenter study
    • Di Zenzo G., Thoma-Uszynski S., Calabresi V., Fontao L., Hofmann S.C., Lacour J.P., et al. Demonstration of epitope-spreading phenomena in bullous pemphigoid: results of a prospective multicenter study. J. Invest. Dermatol. 2011, 131:2271-2280.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 2271-2280
    • Di Zenzo, G.1    Thoma-Uszynski, S.2    Calabresi, V.3    Fontao, L.4    Hofmann, S.C.5    Lacour, J.P.6
  • 33
    • 77949538894 scopus 로고    scopus 로고
    • Sequential intramolecular epitope spreading of humoral responses to human BPAG2 in a transgenic model
    • Di Zenzo G., Calabresi V., Olasz E.B., Zambruno G., Yancey K.B. Sequential intramolecular epitope spreading of humoral responses to human BPAG2 in a transgenic model. J. Invest. Dermatol. 2010, 130:1040-1047.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 1040-1047
    • Di Zenzo, G.1    Calabresi, V.2    Olasz, E.B.3    Zambruno, G.4    Yancey, K.B.5
  • 34
    • 78650633489 scopus 로고    scopus 로고
    • Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model
    • Li Q., Ujiie H., Shibaki A., Wang G., Moriuchi R., Qiao H.J., et al. Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model. J. Immunol. 2010, 185:7746-7755.
    • (2010) J. Immunol. , vol.185 , pp. 7746-7755
    • Li, Q.1    Ujiie, H.2    Shibaki, A.3    Wang, G.4    Moriuchi, R.5    Qiao, H.J.6
  • 36
    • 76149144802 scopus 로고    scopus 로고
    • Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody fragments against pathogenic autoantigen
    • Wang G., Ujiie H., Shibaki A., Nishie W., Tateishi Y., Kikuchi K., et al. Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody fragments against pathogenic autoantigen. Am. J. Pathol. 2010, 176:914-925.
    • (2010) Am. J. Pathol. , vol.176 , pp. 914-925
    • Wang, G.1    Ujiie, H.2    Shibaki, A.3    Nishie, W.4    Tateishi, Y.5    Kikuchi, K.6
  • 37
    • 85042610490 scopus 로고    scopus 로고
    • IgG from patients with bullous pemphigoid depletes cultured keratinocytes of the 180-kDa bullous pemphigoid antigen (type XVII collagen) and weakens cell attachment
    • Iwata H., Kamio N., Aoyama Y., Yamamoto Y., Hirako Y., Owaribe K., et al. IgG from patients with bullous pemphigoid depletes cultured keratinocytes of the 180-kDa bullous pemphigoid antigen (type XVII collagen) and weakens cell attachment. J. Invest. Dermatol. 2009, 129:919-926.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 919-926
    • Iwata, H.1    Kamio, N.2    Aoyama, Y.3    Yamamoto, Y.4    Hirako, Y.5    Owaribe, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.