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Volumn 65, Issue 1, 2012, Pages 9-13

Efflux pump genes and antimicrobial resistance of Pseudomonas aeruginosa strains isolated from lower respiratory tract infections acquired in an intensive care unit

Author keywords

intensive care unit; lower respiratory tract infection; P. aeruginosa; resistance genes

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE; BACTERIAL PROTEIN; BETA LACTAMASE AMPC; CARBAPENEMASE; CEFEPIME; CIPROFLOXACIN; IMIPENEM; MEROPENEM; MEXC PROTEIN; MEZLOCILLIN; NFXB PROTEIN; NORFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM; TOBRAMYCIN; UNCLASSIFIED DRUG;

EID: 84856497696     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.102     Document Type: Article
Times cited : (26)

References (25)
  • 1
    • 4444240819 scopus 로고    scopus 로고
    • Nosocomial lung infections in adult intensive care units
    • DOI 10.1016/j.micinf.2004.05.019, PII S1286457904002035
    • Hernández, G., Rico, P., Díaz, E. & Rello, J. Nosocomial lung infections in adult intensive care units. Microbes Infect. 6, 1004-1014 (2004). (Pubitemid 39166043)
    • (2004) Microbes and Infection , vol.6 , Issue.11 , pp. 1004-1014
    • Hernandez, G.1    Rico, P.2    Diaz, E.3    Rello, J.4
  • 2
    • 0033947513 scopus 로고    scopus 로고
    • Nosocomial pulmonary infection by antimicrobial-resistant bacteria of patients hospitalized in intensive care units: Risk factors and survival
    • DOI 10.1053/jhin.2000.0752
    • Vanhems, P. et al. Nosocomial pulmonary infection by antimicrobial- resistant bacteria of patients hospitalized in intensive care units: risk factors and survival. J. Hosp. Infect. 45, 98-106 (2000). (Pubitemid 30438973)
    • (2000) Journal of Hospital Infection , vol.45 , Issue.2 , pp. 98-106
    • Vanhems, P.1    Lepape, A.2    Savey, A.3    Jambou, P.4    Fabry, J.5
  • 3
    • 0033836084 scopus 로고    scopus 로고
    • Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria
    • DOI 10.1128/AAC.44.9.2233-2241.2000
    • Poole, K. Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria. Antimicrob. Agents Chemother. 44, 2233-2241 (2000). (Pubitemid 30650861)
    • (2000) Antimicrobial Agents and Chemotherapy , vol.44 , Issue.9 , pp. 2233-2241
    • Poole, K.1
  • 4
    • 0035087832 scopus 로고    scopus 로고
    • Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms
    • Poole, K. Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms. J. Mol. Microbiol. Biotechnol. 3, 255-264 (2001).
    • (2001) J. Mol. Microbiol. Biotechnol. , vol.3 , pp. 255-264
    • Poole, K.1
  • 5
    • 84856509043 scopus 로고    scopus 로고
    • 8th edn (eds Muray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH) (ASM Press, Washington
    • Kiska, D. L. & Gilligan, P. H. In: Man. Clin. Microbio. 8th edn (eds Muray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH) (ASM Press, Washington, 2003).
    • (2003) Man. Clin. Microbio.
    • Kiska, D.L.1    Gilligan, P.H.2
  • 6
    • 33646696219 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute, CLSI document M100-S21 (Clinical and Laboratory Standards Institute, Wayne, Pennsylvania, USA
    • Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing-Nineteenth Informational Supplement. CLSI document M100-S21 (Clinical and Laboratory Standards Institute, Wayne, Pennsylvania, USA, 2011).
    • (2011) Performance Standards for Antimicrobial Susceptibility Testing-Nineteenth Informational Supplement
  • 7
    • 0027215943 scopus 로고
    • A simple and rapid method for the preparation of gram-negative bacterial genomic DNA
    • Chen, W. & Kuo, T. A simple and rapid method for the preparation of gram negative bacterial genomic DNA. Nucleic Acids Res. 21, 2260 (1993). (Pubitemid 23160759)
    • (1993) Nucleic Acids Research , vol.21 , Issue.9 , pp. 2260
    • Chen, W.-P.1    Kuo, T.-T.2
  • 8
    • 33644862846 scopus 로고    scopus 로고
    • Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR
    • Dumas, J. L., van Delden, C., Peron, K. & Köhler, T. Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR. FEMS Microbiol. Lett. 254, 217-225 (2006).
    • (2006) FEMS Microbiol. Lett. , vol.254 , pp. 217-225
    • Dumas, J.L.1    Van Delden, C.2    Peron, K.3    Köhler, T.4
  • 9
    • 24644515282 scopus 로고    scopus 로고
    • Overview of nosocomial infections caused by gram-negative bacilli
    • DOI 10.1086/432803
    • Gaynes, R. & Edwards, J. R. Overview of nosocomial infections caused by gram-negative bacilli. Clin. Infect. Dis. 41, 848-854 (2005). (Pubitemid 41266753)
    • (2005) Clinical Infectious Diseases , vol.41 , Issue.6 , pp. 848-854
    • Gaynes, R.1    Edwards, J.R.2
  • 10
    • 0038673434 scopus 로고    scopus 로고
    • Surveillance for antimicrobial susceptibility among clinical isolates of Pseudomonas aeruginosa and Acinetobacter baumannii from hospitalized patients in the United States, 1998 to 2001
    • DOI 10.1128/AAC.47.5.1681-1688.2003
    • Karlowsky, J. A., Draghi, D. C., Jones, M. E., Thornsberry, C., Friedland, I. R. & Sahm, D. F. Surveillance for antimicrobial susceptibility among clinical isalates of Pseudomonas aeruginosa and Acinetobacter baumannii from hospitalized patients in the United States, 1998 to 2002. Antimicrob. Agents. Chemother. 47, 1681-1688 (2003). (Pubitemid 36548554)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.5 , pp. 1681-1688
    • Karlowsky, J.A.1    Draghi, D.C.2    Jones, M.E.3    Thornsberry, C.4    Friedland, I.R.5    Sahm, D.F.6
  • 11
    • 34447263017 scopus 로고    scopus 로고
    • Problematic clinical isolates of Pseudomonas aeruginosa from the university hospitals in Sofia, Bulgaria: Current status of antimicrobial resistance and prevailing resistance mechanisms
    • DOI 10.1099/jmm.0.46986-0
    • Strateva, T., Ouzounova Raykova, V., Markova, B., Todorova, A., Marteva Proevska, Y. & Mitov, I. Problematic clinical isolates of Pseudomonas aeruginosa from the university hospitals in Sofia, Bulgaria: current status of antimicrobial resistance and prevailing resistance mechanisms. J. Med. Microbiol. 56, 956-963 (2007). (Pubitemid 47047490)
    • (2007) Journal of Medical Microbiology , vol.56 , Issue.7 , pp. 956-963
    • Strateva, T.1    Ouzounova-Raykova, V.2    Markova, B.3    Todorova, A.4    Marteva-Proevska, Y.5    Mitov, I.6
  • 13
    • 9644274002 scopus 로고    scopus 로고
    • National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002
    • DOI 10.1128/AAC.48.12.4606-4610.2004
    • Obritsch, M. D., Fish, D. N., MacLaren, R. & Jung, R. National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002. Antimicrob. Agents Chemother. 48, 4606-4610 (2004). (Pubitemid 39577660)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.12 , pp. 4606-4610
    • Obritsch, M.D.1    Fish, D.N.2    MacLaren, R.3    Jung, R.4
  • 14
    • 0038733705 scopus 로고    scopus 로고
    • Expression stability of six housekeeping genes: A proposal for resistance gene quantification studies of Pseudomonas aeruginosa by real-time quantitative RT-PCR
    • Savli, H. et al. Expression stability of six housekeeping genes: a proposal for resistance gene quantification studies of Pseudomonas aeruginosa by real-time quantitative RT-PCR. J. Med. Microbiol. 52, 1-6 (2003).
    • (2003) J. Med. Microbiol. , vol.52 , pp. 1-6
    • Savli, H.1
  • 16
    • 12944262276 scopus 로고    scopus 로고
    • Aminoglycoside resistance in Pseudomonas aeruginosa
    • DOI 10.1128/AAC.49.2.479-487.2005
    • Poole, K. Aminoglycoside resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 49, 479-487 2005. (Pubitemid 40175650)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.2 , pp. 479-487
    • Poole, K.1
  • 17
    • 70349564832 scopus 로고    scopus 로고
    • Characteristics of Pseudomonas aeruginosa isolates from intensive care unit
    • Ozer, B., Tatman-Otkun, M., Memis, D. & Otkun, M. Characteristics of Pseudomonas aeruginosa isolates from intensive care unit. Cent. Eur. J. Med. 4, 156-163 (2009).
    • (2009) Cent. Eur. J. Med. , vol.4 , pp. 156-163
    • Ozer, B.1    Tatman-Otkun, M.2    Memis, D.3    Otkun, M.4
  • 18
  • 19
    • 1642543119 scopus 로고    scopus 로고
    • Enhancement of the mexAB-oprM Efflux Pump Expression by a Quorum-Sensing Autoinducer and Its Cancellation by a Regulator, MexT, of the mexEF-oprN Efflux Pump Operon in Pseudomonas aeruginosa
    • DOI 10.1128/AAC.48.4.1320-1328.2004
    • Maseda, H. et al. Enhancement of the mexAB-oprM efflux pump expression by a quorum-sensing autoinducer and its cancellation by a regulator, MexT, of the mexEFoprN efflux pump operon in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 48, 1320-1328 (2004). (Pubitemid 38405488)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.4 , pp. 1320-1328
    • Maseda, H.1    Sawada, I.2    Saito, K.3    Uchiyama, H.4    Nakae, T.5    Nomura, N.6
  • 20
    • 0036065909 scopus 로고    scopus 로고
    • The MexR repressor of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: Characterization of mutations compromising activity
    • DOI 10.1128/JB.184.15.4308-4312.2002
    • Adewoye, L., Sutherland, A., Srikumar, R. & Poole, K. The MexR repressor of mexABoprM multidrug efflux operon in Pseudomonas aeruginosa: characterization of mutations compromising activity. J. Bacteriol. 184, 4308-4312 (2002). (Pubitemid 34774314)
    • (2002) Journal of Bacteriology , vol.184 , Issue.15 , pp. 4308-4312
    • Adewoye, L.1    Sutherland, A.2    Srikumar, R.3    Poole, K.4
  • 21
    • 33646453620 scopus 로고    scopus 로고
    • Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates
    • Quale, J., Bratu, S., Gupta, J. & Landman, D. Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates. Antimicrob. Agents Chemother. 50, 1633-1641 (2006).
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1633-1641
    • Quale, J.1    Bratu, S.2    Gupta, J.3    Landman, D.4
  • 22
    • 0344131941 scopus 로고    scopus 로고
    • Characterization of MexT, the regulator of the MexE-MexF-OprN multidrug efflux system of Pseudomonas aeruginosa
    • Kohler, T., Epp, S. F., Curty, L. K. & Pechere, J. C. Characterization of MexT, the regulator of the MexE-MexF-OprN multidrug efflux system of Pseudomonas aeruginosa. J. Bacteriol. 181, 6300-6305 (1999). (Pubitemid 29512938)
    • (1999) Journal of Bacteriology , vol.181 , Issue.20 , pp. 6300-6305
    • Kohler, T.1    Epp, S.F.2    Curty, L.K.3    Pechere, J.-C.4
  • 23
    • 0026730399 scopus 로고
    • Interplay of impermeability and chromosomal beta lactamase activity in imipenem-resistant Pseudomonas aeruginosa
    • Livermore, D M. Interplay of impermeability and chromosomal beta lactamase activity in imipenem-resistant Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 36, 2046-2048 (1992).
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 2046-2048
    • Livermore, D.M.1
  • 24
    • 33744950954 scopus 로고    scopus 로고
    • Potency of carbapenems for the prevention of carbapenem-resistant mutants of Pseudomonas aeruginosa: The high potency of a new carbapenem doripenem
    • Sakyo, S., Tomita, H., Tanimoto, K., Fujimoto, S. & Ike, Y. Potency of carbapenems for the prevention of carbapenem-resistant mutants of Pseudomonas aeruginosa. J. Antibiot. 59, 220-228 (2006). (Pubitemid 43854733)
    • (2006) Journal of Antibiotics , vol.59 , Issue.4 , pp. 220-228
    • Sakyo, S.1    Tomita, H.2    Tanimoto, K.3    Fujimoto, S.4    Ike, Y.5
  • 25
    • 49649093171 scopus 로고    scopus 로고
    • Occurrence and mechanisms of amikacin resistance and its association with beta-lactamases in Pseudomonas aeruginosa: A Korean nationwide study
    • Kim, J. Y. et al. Occurrence and mechanisms of amikacin resistance and its association with beta-lactamases in Pseudomonas aeruginosa: a Korean nationwide study. J. Antimicrob. Chemother. 62, 479-483 (2008).
    • (2008) J. Antimicrob. Chemother. , vol.62 , pp. 479-483
    • Kim, J.Y.1


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