Pilocarpine-induced status epilepticus and subsequent spontaneous seizures: Lack of effect on the number of gonadotropin-releasing hormone-positive neurons in a mouse model of temporal lobe epilepsy

Neuroscience

Volumn 203, Issue , 2012, Pages 153-159

  Fawley, J A ^a,b   Pouliot, W A ^a,b   Dudek, F E ^a,b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

CA1 area; CA3 area; Catamenial epilepsy; Estrous cycle; Neuronal loss; Reproductive disorders

Indexed keywords

DIAZEPAM; GONADORELIN; PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL COUNT; CELL LOSS; CONTROLLED STUDY; EPILEPTIC STATE; ESTRUS CYCLE; FEMALE; HIPPOCAMPUS; HORMONE RELEASE; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENT DISEASE; SEIZURE; TEMPORAL LOBE EPILEPSY;

ANIMALS; CELL COUNT; EPILEPSY, TEMPORAL LOBE; ESTROUS CYCLE; FEMALE; GONADOTROPIN-RELEASING HORMONE; HIPPOCAMPUS; MICE; NEURONS; PILOCARPINE; SEIZURES; STATUS EPILEPTICUS;

EID: 84856480338     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.12.026     Document Type: Article

References (29)

1. Amado D., Cavalheiro E.A. Hormonal and gestational parameters in female rats submitted to the pilocarpine model of epilepsy. Epilepsy Res 1998, 32:266-274.
2. Amado D., Cavalheiro E.A., Bentivoglio M. Epilepsy and hormonal regulation: the patterns of GnRH and galanin immunoreactivity in the hypothalamus of epileptic female rats. Epilepsy Res 1993, 14:149-159.
3. Amado D., Verreschi I.T., Berzaghi M.P., Cavalheiro E.A. Effects of intrahippocampal injection of kainic acid on estrous cycle in rats. Braz J Med Biol Res 1987, 20:829-832.
4. Borges K., Gearing M., McDermott D.L., Smith A.B., Almonte A.G., Wainer B.H., Dingledine R. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Exp Neurol 2003, 182:21-34.
5. Buckmaster P.S., Dudek F.E. Network properties of the dentate gyrus in epileptic rats with hilar neuron loss and granule cell axon reorganization. J Neurophysiol 1997, 77:2685-2696.
6. Cavalheiro E.A., Santos N.F., Priel M.R. The pilocarpine model of epilepsy in mice. Epilepsia 1996, 37:1015-1019.
7. Curia G., Longo D., Biagini G., Jones R.S., Avoli M. The pilocarpine model of temporal lobe epilepsy. J Neurosci Methods 2008, 172:143-157.
8. Drislane F.W., Coleman A.E., Schomer D.L., Ives J., Levesque L.A., Seibel M.M., Herzog A.G. Altered pulsatile secretion of luteinizing hormone in women with epilepsy. Neurology 1994, 44:306-310.
9. Dudek F.E., Hellier J.L., Williams P.A., Ferraro D.J., Staley K.J. The course of cellular alterations associated with the development of spontaneous seizures after status epilepticus. Prog Brain Res 2002, 135:53-65.
10. Edwards H.E., Burnham W.M., Ng M.M., Asa S., MacLusky N.J. Limbic seizures alter reproductive function in the female rat. Epilepsia 1999, 40:1370-1377.
11. Edwards H.E., MacLusky N.J., Burnham W.M. The effect of seizures and kindling on reproductive hormones in the rat. Neurosci Biobehav Rev 2000, 24:753-762.
12. Everett J.W. Pituitary and hypothalamus: perspectives and overview. The physiology of reproduction 1994, 1509-1526. Raven Press, New York. E. Knobil, J.D. Neill (Eds.).
13. Friedman M.N., Geula C., Holmes G.L., Herzog A.G. GnRH-immunoreactive fiber changes with unilateral amygdala-kindled seizures. Epilepsy Res 2002, 52:73-77.
14. Herbison A.E., Porteous R., Pape J.R., Mora J.M., Hurst P.R. Gonadotropin-releasing hormone neuron requirements for puberty, ovulation, and fertility. Endocrinology 2008, 149:597-604.
15. Herzog A.G. Disorders of reproduction in patients with epilepsy: primary neurological mechanisms. Seizure 2008, 17:101-110.
16. Levine J.E., Ramirez V.D. Luteinizing hormone-releasing hormone release during the rat estrous cycle and after ovariectomy, as estimated with push-pull cannulae. Endocrinology 1982, 111:1439-1448.
17. Lloyd J.M., Hoffman G.E., Wise P.M. Decline in immediate early gene expression in gonadotropin-releasing hormone neurons during proestrus in regularly cycling, middle-aged rats. Endocrinology 1994, 134:1800-1805.
18. Mathern G.W., Adelson P.D., Cahan L.D., Leite J.P. Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Prog Brain Res 2002, 135:237-251.
19. Morrell M.J. Effects of epilepsy on women's reproductive health. Epilepsia 1998, 39(Suppl 8):S32-S37.
20. Nappi C., Meo R., Di Carlo C., Estraneo A., Bilo L. Reduced fertility and neuroendocrine dysfunction in women with epilepsy. Gynecol Endocrinol 1994, 8:133-145.
21. Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol 1972, 32:281-294.
22. Scharfman H.E., Kim M., Hintz T.M., MacLusky N.J. Seizures and reproductive function: insights from female rats with epilepsy. Ann Neurol 2008, 64:687-697.
23. Shibley H., Smith B.N. Pilocarpine-induced status epilepticus results in mossy fiber sprouting and spontaneous seizures in C57BL/6 and CD-1 mice. Epilepsy Res 2002, 49:109-120.
24. Silverman A.J., Witkin J.W. Biosynthesis of gonadotropin-releasing hormone during the rat estrous cycle: a cellular analysis. Neuroendocrinology 1994, 59:545-551.
25. Suter K.J., Song W.J., Sampson T.L., Wuarin J.P., Saunders J.T., Dudek F.E., Moenter S.M. Genetic targeting of green fluorescent protein to gonadotropin-releasing hormone neurons: characterization of whole-cell electrophysiological properties and morphology. Endocrinology 2000, 141:412-419.
26. Sutula T.P., Hagen J., Pitkänen A. Do epileptic seizures damage the brain?. Curr Opin Neurol 2003, 16:189-195.
27. Taylor A.E., McCourt B., Martin K.A., Anderson E.J., Adams J.M., Schoenfeld D., Hall J.E. Determinants of abnormal gonadotropin secretion in clinically defined women with polycystic ovary syndrome. J Clin Endocrinol Metab 1997, 82:2248-2256.
28. Turski W.A., Cavalheiro E.A., Bortolotto Z.A., Mello L.M., Schwarz M., Turski L. Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis. Brain Res 1984, 321:237-253.
29. Turski W.A., Cavalheiro E.A., Schwarz M., Czuczwar S.J., Kleinrok Z., Turski L. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res 1983, 9:315-335.