A pilot scale study on the fluidized bed binderless granulation of a humidified type C hygroscopic pharmaceutical material

Powder Technology

Volumn 219, Issue , 2012, Pages 65-71

  Kwek, J W ^a   Lim, M W ^a   Shen, S C ^a   Ng, W K ^a   Tan, Reginald B H ^a,b  

^a INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Drying step; Fluidization; Granulation; Humidification; Pilot scale

Indexed keywords

AEROSOLIZATION; COMMERCIAL PRODUCTS; DRY POWDER INHALER; DRYING STEP; FINE PARTICLE FRACTIONS; FLOW PROPERTIES; FLUIDIZED BED GRANULATION; FLUIDIZED BED GRANULATOR; HUMIDIFICATION; INTERNAL DIAMETERS; PARTICLE MORPHOLOGIES; PHARMACEUTICAL MATERIALS; PILOT SCALE; PILOT-SCALE STUDY; PRODUCT QUALITY; TECHNICAL FEASIBILITY; WET AIR;

DRIERS (MATERIALS); DRYING; ELECTRIC IMPEDANCE; FLUIDIZATION; FLUIDIZED BED PROCESS; GRANULATION;

FLUIDIZED BEDS;

AEROSOL; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG GRANULATION; FLOW RATE; FLUIDIZATION; FLUIDIZED BED; HUMIDIFIER; MOISTURE; PARTICLE SIZE; POWDER INHALER; PROCESS OPTIMIZATION; WETTABILITY;

EID: 84856476361     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2011.12.010     Document Type: Article

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