Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors

Journal of Biochemistry

Volumn 151, Issue 2, 2012, Pages 167-178

  Murakawa, Takeshi ^a   Hayashi, Hideyuki ^a   Taki, Masayasu ^b   Yamamoto, Yukio ^b   Kawano, Yoshiaki ^c   Tanizawa, Katsuyuki ^d   Okajima, Toshihide ^a,d  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

copper amine oxidase; irreversible inhibitor; substrate specificity; topa quinone; X ray crystal structure

Indexed keywords

4 HYDROXYBENZYLHYDRAZINE; AMINE OXIDASE (COPPER CONTAINING); BENZYLAMINE; BENZYLHYDRAZINE; ENZYME INHIBITOR; HYDRAZINE DERIVATIVE; HYDRAZONE DERIVATIVE; NITROGEN; PHENETHYLAMINE; PHENYLHYDRAZINE; QUINONE DERIVATIVE; SCHIFF BASE; TYRAMINE; UNCLASSIFIED DRUG;

ARTHROBACTER GLOBIFORMIS; ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; HYDROLYSIS; NONHUMAN;

AMINE OXIDASE (COPPER-CONTAINING); ARTHROBACTER; BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; DIHYDROXYPHENYLALANINE; ENZYME INHIBITORS; HYDRAZINES; HYDROLYSIS; KINETICS; OXIDATION-REDUCTION; SCHIFF BASES; SUBSTRATE SPECIFICITY;

ARTHROBACTER GLOBIFORMIS; BACTERIA (MICROORGANISMS);

EID: 84856470642     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvr125     Document Type: Article

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