The effects of Fumaria parviflora L extract on chronic hand eczema: A randomized double-blind placebo controlled clinical trial

Iranian Red Crescent Medical Journal

Volumn 13, Issue 11, 2011, Pages 824-828

  Jowkar, F ^a   Jamshidzadeh, A ^b   Yazdi, A Mirzadeh ^a   Pasalar, M ^c  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Eczema; Fumaria parviflora; Fumaric acid

Indexed keywords

ALCOHOL; FUMARIA PARVIFLORA EXTRACT; PLACEBO; PLANT EXTRACT; POLYPHENOL; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; APPLICATION SITE EXCORIATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CREAM; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; ERYTHEMA; FEMALE; HAND ECZEMA; HUMAN; MALE; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION;

EID: 84856443860     PISSN: 20741804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Holden CA, Berth-Jones J. Eczema, Lichenification, Prurigo and Erythroderma. In: Burns T, Breathnach S, Cox N, Greffiths C. Rook 's Text book of Dermatology. 8 th edition. Wiley-Blackwell, Oxford: 2010; p. 876-934.
2. James WD, Berger TG, Elson DM. Andrews' Diseases of the skin clinical dermatology. Saunders company, Philadelphia, 2005; p. 78-83.
3. Avicenna. A1 Qanun Fil Tibb. Jamia Hamdard printing press, New Delhi, 1998; p. 425-691. [English translation]
4. Mills S, Bone K. Principals and practice of phytotherapy modern herbal medicine. Churchill Livingstone, London, 2000; p. 254.
5. Hagerman A, Harvey-Mueller I, Makkar HPS. Quantification of Tannins in Tree Foliage-A Laboratory Manual for FAO/IAEA. IAEA 2000; 1:21-24.
6. Hanifin JM, Thurston M, Omoto M, Cherill R, Tofte SJ, Graeber M. The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. Exp Dermatol 2001;10:11-18. [11168575] [http://dx.doi.org/10.1034/j.1600-0625.2001.100102.x]
7. Hentschel C, Dressler S, Hahn EG. Fumaria officinalis (Fumitory)- clinical applications. Fortscher Med 1995;113:291-292. [7672742]
8. Harvies MJ, Chalmers RJ, Griffiths CE. Fumaric acid esters for severe psoriasis: a retrospective review of 58 cases. Br J Dermatol 2005;153: 549-551. [16120141] [http://dx.doi.org/10.1111/j.1365-2133.2005.06728.x]
9. Sousek J, Guedon D, Adam T, Bochorakova H, Toborska E, Valka I, Simanek V. Alkaloids and organic acids content of eight Fumaria species. Phytochem Anal 1999;10:6-11. [http://dx.doi.org/10.1002/(SICI)1099-1565(199901/02)10:16::AID-PCA4313.0.CO;2-0]
10. Khalighi-Sigaroodi F, Yazdani D, Taghizadeh M, Rezazadeh Sh. Quantitative determination of an effective component of Fumaria parviflora lam. J Med Plant 2005;41:62-71.
11. Litjens NH, Rademaker M, Ravensbergen B, Rea D, van der Plas MJ, Thio B, Walding A, van Dissel JT, Nibbering PH. Monomethylefumarate affects polarization of monocyte- derived dendritic cells resulting in down-regulated the lymphocyte responses. Eur J Immunol 2004; 34:565-575. [14768062] [http://dx.doi.org/10.1002/eji.200324174]
12. Kreuter A, Knierim C, Stücker M, Pawlak F, Rotterdam S, Altmeyer P, Gambichler T. Fumaric acid esters in necrobiosis lipoidica: results of a prospective non cotrolled study. Br J Dermatol 2005;153:802-807. [16181 464] [http://dx.doi.org/10.1111/j.1365-2133.2005.06762.x]
13. Breuer K, Gutzmer R, Volker B, Werfel T. Therapy of noninfections granulomatous skin diseases with fumaric acid esters. Br J Dermatol 2005;152:1290-1295. [15948995] [http://dx.doi.org/10.1111/j.1365-2133.2005.06585.x]
14. Lehmann M, Risch K, Nizze H, Lutz J, Heemann U, Volk HD, Asadullah K. Fumaric acid esters are potent immunosuppressants: inhibition of acute and chronic rejection in rat kidney transplantation models by methyl hydrogen fumarate. Arch Dermatol Res 2002;294:399-404. [12522577]
15. Zhu K, Morwietz U. Inhibition if dendritic cell differentiation by fumaric acid esters. J Invest Dermatol 2001; 116:203-208. [11179994] [http://dx.doi.org/10.1046/j.1523-1747.2001.01159.x]
16. Litjens NH, Rademaker M, Ravensbergen B, Thio HB, van Dissel JT, Nibbering PH. Effects of monomethylfumarate on dendritic cell differentiation. Br J Dermatol 2006; 154: 211-217. [1643378] [http://dx.doi.org/10.1111/j.1365-2133.2005.07002.x]
17. Martindale W. Martindale the Extra Pharmacopeia. Pharmaceutical Press, London, 2007; p. 75-83.