Gastroprotective effect of Achyranthes aspera Linn. leaf on rats

Asian Pacific Journal of Tropical Medicine

Volumn 5, Issue 3, 2012, Pages 197-201

  Das, Ashish K ^a   Bigoniya, Papiya ^a   Verma, Neelesh K ^a   Rana, A C ^b  

^a Radharaman College of Pharmacy   (India)

^b Rayat College of Pharmacy   (India)

Author keywords

Achyranthes aspera; Antiulcer; Ethanol; Gastroprotective; Omeprazole

Indexed keywords

ACHYRANTHES ASPERA EXTRACT; ALCOHOL; ALKALOID; CARBOHYDRATE; FLAVONOID; GLYCOSIDE; OMEPRAZOLE; SAPONIN; STEROID; TANNIN DERIVATIVE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIULCER ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; DRUG MEGADOSE; DRUG SCREENING; FEMALE; MALE; MOUTH DISEASE; NONHUMAN; PHYTOCHEMISTRY; PLANT LEAF; PRIORITY JOURNAL; PYLORUS LIGATION; RAT; STOMACH CONTENT; STOMACH JUICE; STOMACH PH; STOMACH PROTECTION; STOMACH ULCER; STOMACH VOLUME; TOXICITY TESTING; TREATMENT RESPONSE; ULCER;

ACHYRANTHES; ANIMALS; ANTI-ULCER AGENTS; CHRONIC DISEASE; ETHANOL; GASTRIC JUICE; HYDROGEN-ION CONCENTRATION; LIGATION; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; SOLVENTS; STOMACH ULCER;

EID: 84856429519     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(12)60024-8     Document Type: Article

References (34)

1. Tripathi KD Essentials of medical pharmacology 1999, 628. Jaypee Brothers Medical Publishers, New Delhi. 4th ed.
2. Goel RK, Bhattacharya SK Gastroduodenal mucosal defence and mucosal protective agents. Indian J Exp Biol 1991, 29:701-714.
3. Hoogerwerf WA, Pasricha PJ Agents used for the control of gastric acidity and treatment of peptic ulcers and gastrooesopahgeal reflux diseases. Goodman and Gilman's: The pharmacological basis of therapeutics 2001, 1005-1019. McGraw-Hill, New York. 10th ed. J.G. Hardman, L.E. Limbrid, C.S. Goodman, B.T. Gilman (Eds.).
4. +ATPase. Annu Rev Pharmacol Toxicol 1995, 35:277-305.
5. Martelli A, Mattlioli F, Mereto E, Brambilla CG, Sini D, Bergamaschi R, et al. Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays. Toxicology 1998, 30:19-41.
6. Wolfef MM, Sachs G Acid suppression: optimizing therapy for gastroduodenal ulcer healing, gastrooesophageal disease and stress-related erosive syndrome. Gastroenterology 2000, 118:S9-S31.
7. Goel RK, Sairam K Antiulcer drugs from indigenous sources with emphasis on Musa sapientum, Tamrabhasna, Asparagus racemosus and Zingiber officinale. Ind J Pharmacol 2002, 34:100-110.
8. Sairam K, Rao CV, Goel RK Effect of Centella asiatica Linn. on physical and chemical factors induced gastric ulceration and secretion. Indian J Exp Biol 2001, 39:137.
9. Sairam K, Rao CV, Goel RK Effect of Convolvulus pluricaulis Chois on gastric ulceration and secretion in rats. Indian J Exp Biol 2001, 39:350.
10. Barua CC, Talukdar A, Begum SA, Lahon LC, Sharma DK, Pathak DC, et al. Antinociceptive activity of methanolic extract of leaves of A. aspera Linn. in animal models of nociception. Indian J Exp Biol 2010, 48:817-821.
11. Kokate CK, Purohit CK, Gokhale SB Pharmacognosy 1996, 510-512. Nirali Prakashan, Pune.
12. Diener W, Mischke U, Kayser D, Schlede E The evaluation of the OECD modified version of acute toxicity class method (oral). Arch Toxicol 1995, 69:729-734.
13. Rao CV, Verma AR, Vijayakumar, Rastogi S Gastroprotective effect of standardized extract of Ficus glomerata on experimental gastric ulcers in rats. J Ethnopharmacol 2008, 115:323-326.
14. Hernández-Muñoz R, Montiel-Ruíz C, Vázquez-Martínez O Gastric mucosal cell proliferation in ethanol-induced chronic mucosal injury is related to oxidative stress and lipid peroxidation in rats. Lab Invest 2000, 80:1161-1169.
15. Roy SP, Shirode D, Patel T, Prabhu K, Setty SR, Rajendra SV Antiulcer activity of 70% ethanolic extract of bark of Madhuca longifolia. Indian J Nat Prod 2008, 24(4):8-10.
16. Hawk A Hawk's physiological chemistry 1965, 483-485. McGraw-Hill Book Co., New York. 14th ed.
17. Kulkarni SK Handbook of experimental pharmacology 2002, 148. Vallabh Prakashan, New Delhi.
18. Kumar MM, Joshi MC, Prabha T, Dorababu M, Goel RK Effect of plantain banana on gastric ulceration in NIDDM rats: Role of gastric mucosal glycoprotein's, cell proliferation, antioxidants and free radicals. Indian J Exp Biol 2006, 44:292-299.
19. Trivedi NP, Rawal UM Hepatoprotective and antioxidant property of Andrographis paniculata Nees in BHC induced liver damage in mice. Indian J Exp Biol 2001, 39:41-46.
20. Ligumsky M, Sestieri M, Okon F, Ginsburg I Antioxidants inhibit ethanol-induced gastric injury in the rat. Role of manganese, glycin and carotene. Scandanavian J Gastroenterol 1995, 30:854-860.
21. Black BA, Morris GP, Wallace JL Effects of acid on the basal lamina of the rat stomach and duodenum. Virchows Arch B Cell Pathol Incl Mol Pathol 1985, 50:109-118.
22. Yoshikawa T, Ichikawa H, Naito Y, Kondo M Role of leukotrienes in gastric mucosal injury induced by ischemia-reperfusion in the rats. J Clin Gastroenterol 1992, 14:568-570.
23. Akowuah GA, Sadikun A, Mariam A Flavonoid identification and hypoglycemic studies of butanol fraction from Gynura procumbens. Pharma Biol 2002, 40:405-410.
24. Saurez J, Herreta MD, Marhuenda E Hesperidin and neohesperidin dihydrochalcone on different experimental models of induced gastric ulcer. Phytother Res 1996, 10:616-618.
25. Zayachkivska OS, Konturek SJ, Drozdowicz D, Konturek PC, Brzozowski T, Ghegotsky MR Gastroprotective effects of flavonoids in plant extracts. J Physiol Pharmacol 2005, 56:219-231.
26. Martin MJ, Marhuenda E, Perez-Guerrero C, Franco JM Antiulcer effect of naringin on gastric lesion induced by ethanol in rats. Pharmacology 1994, 49:144-150.
27. Gonzaler FG, Di Stasi LC Anti-ulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice. Phytomedicine 2002, 9(2):125-134.
28. Aguwa CN Gastrointestinal effects of the extracts of Rhigiocarya racemifera (Menispermaceae). Gen Pharmacol 1985, 16(4):387-390.
29. Brodie DA The mechanism of gastric hyperacidity produced by pyloric ligation in the rat. Am J Dig Dis 1966, 11:231-241.
30. Goswami S, Jain S, Santani D Antiulcer activity of cromakalim, against experimentally induced gastric and duodenal ulcers in rats and guinea pigs. J Pharm Pharmacol 1997, 49:195-199.
31. Hernández-Muñoz R, Montiel-Ruíz F Reversion by histamine H2-receptor antagonists of plasma membrane alterations in ethanol-induced gastritis. Dig Dis Sci 1996, 41:2156-2165.
32. Sood S, Muthuraman A Activity of tacrolimus: An immunosuppressant, in pyloric ligation induced peptic ulcer in rat. J Pharm Soc Japan 2009, 129(12):1523-1528.
33. Eissele R, Roakoph B, Koop H, Alder G, Arnold R Proliferation of endocrine cells in the rat stomach caused by drug-induced achlorhydria. Gastroenterology 1991, 101:70-76.
34. Alvarez A, Pomar F, Sevilla MA, Montero MJ Gastric antisecretory and antiulcer activities of ethanolic extract of Bidens pilosa L. var. radiate Schult. Bip J Ethnopharmacol 1999, 67(3):333-340.