Risk conferred by Fokl polymorphism of vitamin D receptor (VDR) gene for essential hypertension

Indian Journal of Human Genetics

Volumn 17, Issue 3, 2011, Pages 201-206

  Swapna, N ^a   Mohana Vamsi, U ^a   Usha, G ^a,b   Padma, T ^a  

^a OSMANIA UNIVERSITY   (India)

^b Department of Cardiology   (India)

Author keywords

Essential hypertension; risk prediction; VDR gene Fok I polymorphism; vitamin D

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; VITAMIN D RECEPTOR FOK I PROTEIN;

ADULT; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE COURSE; DNA POLYMORPHISM; ESSENTIAL HYPERTENSION; EXON; FAMILY HISTORY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SEX DIFFERENCE; SMOKING HABIT;

EID: 84856395729     PISSN: 09716866     EISSN: 1998362X     Source Type: Journal    
DOI: 10.4103/0971-6866.92104     Document Type: Article

References (21)

1. Ward R. Familial aggregation and genetic epidemiology of blood pressure. In: Laragh JH, Brenner BM, editors. Hypertension: Pathophysiology, Diagnosis and Management. New York: Raven; 1990. p. 811-100.
2. Li YC, Kong J, Wei M, Chen ZF, Liu SQ, Cao LP. 1, 25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest 2002;110:229-38. (Pubitemid 34787360)
3. Carthy EP, Yamashita W, Hsu A, Ooi BS. 1, 25-Dihydroxyvitamin D3and rat vascular smooth muscle cell growth. Hypertension 1989;13:954-9. (Pubitemid 19157996)
4. Borges AC, Feres T, Vianna LM, Paiva TB. Recovery of impaired K channels in mesenteric arteries from spontaneously hypertensive rats by prolonged treatment with cholecalciferol. Br J Pharmacol 1999;127:772-8. (Pubitemid 29276663)
5. Feres T, Vianna LM, Paiva AC, Paiva TB. Effect of treatment with vitamin D3 on the responses of the duodenum of spontaneously hypertensive rats to bradykinin and to potassium. Br J Pharmacol 1992;105:881-4.
6. Sowers MR, Wallace RB, Lemke JH. The association of intakes of vitamin D and calcium with blood pressure among women. Am J Clin Nutr 1985;42:135-42. (Pubitemid 15028533)
7. Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. J Clin Endocrinol Metab 2001;86:1633-7. (Pubitemid 32377290)
8. Li YC, Qiao G, Uskokovic M, Xiang W, Zheng W, Kong J. Vitamin D: A negative endocrine regulator of the reninangiotensin system and blood pressure J Steroid Biochem Mole Biol 2004;89-90:387-92. (Pubitemid 38844316)
9. Merke J, Milde P, Lewicka S, Hügel U, Klaus G, Mangelsdorf DJ. Identification and regulation of 1,25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1,25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillaries. J Clin Invest 1989;83:1903-15. (Pubitemid 19148859)
10. Merke J, Hofmann W, Goldschmidt D, Ritz E Demonstration of 1,25(OH)2 vitamin D3 receptors and actions in vascular smooth muscle cells in vitro. Calcif Tissue Int 1987;41: 112-4.
11. Van Schooten FJ, Hirvonen A, Maas LM Putative susceptibility markers of coronary artery disease: Association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue. FASEB J 1998;12:1409-17. (Pubitemid 28475583)
12. Taymans SE, Pack S, Pak E, Orban Z, Barsony J, Zhuang ZThe human vitamin D Receptor Gene (VDR) Is localized to region 12cen-q12 by fluorescent in situ hybridization and radiation hybrid mapping: Genetic and physical VDR Map. J Bone Mineral Res 1999;14:1163-6. (Pubitemid 29314059)
13. Crofts LA, Hancock MS, Morrison NA, Eisman JA. Multiple promoters direct the tissue-specific expression of novel N-terminal variant human vitamin D receptor gene transcripts. Proc Natl Acad Sci USA 1998;95:10529-34.
14. Miyamoto K, Kesterson RA, Yamamoto H, Taketani Y, Nishiwaki E, Tatsumi SStructural organization of the human vitamin D receptor chromosomal gene and its promoter. Mol Endocrinol 1997;11:1165-79. (Pubitemid 27278838)
15. WhitfieldGK, Remus LS, Jurutka PW, Zitzer H, Oza AK, Dang HT Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene. Mol Cell Endocrinol 2001;177:145-59. (Pubitemid 32506815)
16. Miller S, Dykes D, Polesky H. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
17. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004;80(6 Suppl):1678-88S.
18. Brown AJ, Dusso A, Slatopolsky E. Vitamin D. Am J Physiol 1999;277:F157-75. (Pubitemid 29415134)
19. Yuan W, Pan W, Kong J, Zheng W, Szeto FL, Wong KE. 1,25-Dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. J Biol Chem 2007;282:29821-30.
20. Resnick LM, Muller FB, Laragh JH. Calcium-regulating hormones in essential hypertension Relation to plasma renin activity and sodium metabolism. Ann Intern Med 1986;105:649-54. (Pubitemid 17176965)
21. Burgess E, Hawkins D, Watanabe RG. Interaction of 1,25-dihydroxyvitamin D and plasma renin activity in high renin essential hypertension. Am J Hypertens 1990;3:903-5.