Chiral separation of Huperzine A using CE - Method validation and application in pharmaceutical formulations

Electrophoresis

Volumn 33, Issue 3, 2012, Pages 516-522

  Tsioupi, Despina A ^a   Nicolaou, Irene N ^a   Moore, Leonard ^b   Kapnissi Christodoulou, Constantina P ^a  

^a UNIVERSITY OF CYPRUS   (Cyprus)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Acetylcholinesterase inhibitor; Enantioseparation; Huperzine A; Pharmaceutical formulation; Polymeric surfactants

Indexed keywords

CHIRALITY; NEURODEGENERATIVE DISEASES;

ACETYLCHOLINESTERASE INHIBITORS; ALZHEIMERS DISEASE; CHIRAL SEPARATIONS; ENANTIOSEPARATIONS; HUPERZINE A; METHOD VALIDATIONS; OPTIMAL CONDITIONS; PHARMACEUTICAL FORMULATION; POLYMERIC SURFACTANT; RESOLUTION TIME;

EFFICIENCY;

ACETIC ACID; HUPERZINE A; POLY(SODIUM N UNDECANOYL LEUCINELEUCINE ALANYL VALINATE); SURFACTANT; TERT BUTYL ALCOHOL; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; CHIRAL SELECTOR; CHIRAL SEPARATION; CONCENTRATION (PARAMETERS); DRUG PURITY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; PARAMETERS; PH; PROCESS OPTIMIZATION; REPRODUCIBILITY; SEPARATION TECHNIQUE; TABLET FORMULATION; TEMPERATURE; VALIDATION PROCESS;

EID: 84856386414     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201100372     Document Type: Article

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