메뉴 건너뛰기




Volumn 160, Issue 2, 2012, Pages 121-130

Metabolomic biomarkers of impaired glucose tolerance and type 2 diabetes mellitus with a potential for risk stratification in women with polycystic ovary syndrome

Author keywords

Impaired glucose tolerance; Metabolomics; Polycystic ovary; Type 2 diabetes

Indexed keywords

ALANINE; ALBUMIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLESTEROL; CHOLINE; CITRIC ACID; CREATININE; FUMARIC ACID; GLUCOSE; GLUTAMINE; GLYCOCHENODEOXYCHOLIC ACID; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; HISTIDINE; HOMOCYSTEINE; INSULIN; ISOLEUCINE; LACTIC ACID; LEUCINE; LOW DENSITY LIPOPROTEIN; LYSINE; MALIC ACID; METHIONINE; METHYLXANTHINE; PHENYLALANINE; SUCCINIC ACID; TYROSINE; URIC ACID; VALINE;

EID: 84856384840     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2011.11.005     Document Type: Review
Times cited : (20)

References (26)
  • 1
    • 2642566238 scopus 로고    scopus 로고
    • Metabolomics - A new exciting field within the "omics" sciences
    • K. Dettmer, and B.D. Hammock Metabolomics - a new exciting field within the "omics" sciences Environ Health Perspect 112 7 2004 A396 A397
    • (2004) Environ Health Perspect , vol.112 , Issue.7
    • Dettmer, K.1    Hammock, B.D.2
  • 2
    • 78349268757 scopus 로고    scopus 로고
    • Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules
    • pii: 525497
    • I. Kouskoumvekaki, and G. Panagiotou Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules J Biomed Biotechnol 2011 2011 pii: 525497
    • (2011) J Biomed Biotechnol , pp. 2011
    • Kouskoumvekaki, I.1    Panagiotou, G.2
  • 3
    • 70350560562 scopus 로고    scopus 로고
    • Metabolomics applied to diabetes research: Moving from information to knowledge
    • J.R. Bain, R.D. Stevens, B.R. Wenner, O. Ilkayeva, D.M. Muoio, and C.B. Newgard Metabolomics applied to diabetes research: moving from information to knowledge Diabetes 58 11 2009 2429 2443
    • (2009) Diabetes , vol.58 , Issue.11 , pp. 2429-2443
    • Bain, J.R.1    Stevens, R.D.2    Wenner, B.R.3    Ilkayeva, O.4    Muoio, D.M.5    Newgard, C.B.6
  • 4
    • 70449450345 scopus 로고    scopus 로고
    • Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses
    • X. Zhang, Y. Wang, and F. Hao Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses J Proteome Res 8 11 2009 5188 5195
    • (2009) J Proteome Res , vol.8 , Issue.11 , pp. 5188-5195
    • Zhang, X.1    Wang, Y.2    Hao, F.3
  • 5
    • 77954457972 scopus 로고    scopus 로고
    • Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits
    • X. Zhao, J. Fritsche, and J. Wang Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits Metabolomics 6 3 2010 362 374
    • (2010) Metabolomics , vol.6 , Issue.3 , pp. 362-374
    • Zhao, X.1    Fritsche, J.2    Wang, J.3
  • 7
    • 42049105149 scopus 로고    scopus 로고
    • Medical therapy in women with polycystic ovarian syndrome before and during pregnancy and lactation
    • N. Goldenberg, and C. Glueck Medical therapy in women with polycystic ovarian syndrome before and during pregnancy and lactation Minerva Ginecol 60 2008 63 75 (Pubitemid 351517723)
    • (2008) Minerva Ginecologica , vol.60 , Issue.1 , pp. 63-75
    • Goldenberg, N.1    Glueck, C.2
  • 8
    • 38149053665 scopus 로고    scopus 로고
    • Pregnancy complications in women with polycystic ovary syndrome
    • C.M. Boomsma, B.C. Fauser, and N.S. Macklon Pregnancy complications in women with polycystic ovary syndrome Semin Reprod Med 26 2008 72 84
    • (2008) Semin Reprod Med , vol.26 , pp. 72-84
    • Boomsma, C.M.1    Fauser, B.C.2    MacKlon, N.S.3
  • 9
    • 33645851024 scopus 로고    scopus 로고
    • The presence of antibodies to oxidative modified proteins in serum from polycystic ovary syndrome patients
    • J.R. Palacio, A. Iborra, Z. Ulcova-Gallova, R. Badia, and P. Martinez The presence of antibodies to oxidative modified proteins in serum from polycystic ovary syndrome patients Clin Exp Immunol 144 2006 217 222
    • (2006) Clin Exp Immunol , vol.144 , pp. 217-222
    • Palacio, J.R.1    Iborra, A.2    Ulcova-Gallova, Z.3    Badia, R.4    Martinez, P.5
  • 10
    • 0028998166 scopus 로고
    • A disorder without identity: "hCA", "pCO", "pCOD", "pCOS", "sLS". What are we to call it?
    • R.A. Lobo A disorder without identity: "HCA", "PCO", "PCOD", "PCOS", "SLS". What are we to call it? Fertil Steril 63 1995 1158 1159
    • (1995) Fertil Steril , vol.63 , pp. 1158-1159
    • Lobo, R.A.1
  • 13
    • 0030960289 scopus 로고    scopus 로고
    • Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome, and its clinical implications
    • J.E. Nestler Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome, and its clinical implications Semin Reprod Endocrinol 15 1997 111 112
    • (1997) Semin Reprod Endocrinol , vol.15 , pp. 111-112
    • Nestler, J.E.1
  • 14
    • 0142185995 scopus 로고    scopus 로고
    • Insulin-Lowering Agents in the Management of Polycystic Ovary Syndrome
    • DOI 10.1210/er.2002-0015
    • V. De Leo, A. la Marca, and F. Petraglia Insulin-lowering agents in the management of polycystic ovary syndrome Endocr Rev 24 2003 633 667 (Pubitemid 37330585)
    • (2003) Endocrine Reviews , vol.24 , Issue.5 , pp. 633-667
    • De Leo, V.1    La Marca, A.2    Petraglia, F.3
  • 15
    • 77955387187 scopus 로고    scopus 로고
    • Methodological deficits in diagnostic research using '-omics' technologies: Evaluation of the QUADOMICS tool and quality of recently published studies
    • L.A. Parker, N. Gómez Saez, B. Lumbreras, M. Porta, and I. Hernández-Aguado Methodological deficits in diagnostic research using '-omics' technologies: evaluation of the QUADOMICS tool and quality of recently published studies PLoS One 5 7 2010 2 e11419
    • (2010) PLoS One , vol.5 , Issue.7 , pp. 11419
    • Parker, L.A.1    Gómez Saez, N.2    Lumbreras, B.3    Porta, M.4    Hernández-Aguado, I.5
  • 16
    • 34247397544 scopus 로고    scopus 로고
    • Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in type 2 diabetes mellitus patients and healthy volunteers
    • DOI 10.1111/j.1365-2125.2006.02816.x
    • M. van Doorn, J. Vogels, and A. Tas Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in type 2 diabetes mellitus patients and healthy volunteers Br J Clin Pharmacol 63 5 2007 562 574 (Pubitemid 46632578)
    • (2007) British Journal of Clinical Pharmacology , vol.63 , Issue.5 , pp. 562-574
    • Van Doorn, M.1    Vogels, J.2    Tas, A.3    Van Hoogdalem, E.J.4    Burggraaf, J.5    Cohen, A.6    Van Der Greef, J.7
  • 17
    • 78649735772 scopus 로고    scopus 로고
    • Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting
    • K. Suhre, C. Meisinger, and A. Döring Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting PLoS One 5 11 2010 e13953
    • (2010) PLoS One , vol.5 , Issue.11 , pp. 13953
    • Suhre, K.1    Meisinger, C.2    Döring, A.3
  • 18
    • 78149428043 scopus 로고    scopus 로고
    • Insulin sensitivity is reflected by characteristic metabolic fingerprints - A Fourier transform mass spectrometric non-targeted metabolomics approach
    • M. Lucio, A. Fekete, and C. Weigert Insulin sensitivity is reflected by characteristic metabolic fingerprints - a Fourier transform mass spectrometric non-targeted metabolomics approach PLoS One 5 10 2010 e13317
    • (2010) PLoS One , vol.5 , Issue.10 , pp. 13317
    • Lucio, M.1    Fekete, A.2    Weigert, C.3
  • 20
    • 79953737332 scopus 로고    scopus 로고
    • Metabolite profiles and the risk of developing diabetes
    • T.J. Wang, M.G. Larson, and R.S. Vasan Metabolite profiles and the risk of developing diabetes Nat Med 17 4 2011 448 453
    • (2011) Nat Med , vol.17 , Issue.4 , pp. 448-453
    • Wang, T.J.1    Larson, M.G.2    Vasan, R.S.3
  • 21
    • 79951948205 scopus 로고    scopus 로고
    • Lipid levels in polycystic ovary syndrome: Systematic review and meta-analysis
    • R.A. Wild, M. Rizzo, S. Clifton, and E. Carmina Lipid levels in polycystic ovary syndrome: systematic review and meta-analysis Fertil Steril 95 3 2011 1073 1079
    • (2011) Fertil Steril , vol.95 , Issue.3 , pp. 1073-1079
    • Wild, R.A.1    Rizzo, M.2    Clifton, S.3    Carmina, E.4
  • 23
    • 0035202886 scopus 로고    scopus 로고
    • Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio
    • M. Anello, V. Ucciardello, and S. Piro Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio Am J Physiol Endocrinol Metab 281 5 2001 E1082 E1087
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , Issue.5
    • Anello, M.1    Ucciardello, V.2    Piro, S.3
  • 24
    • 34447574828 scopus 로고    scopus 로고
    • Hypoglycemic effect of isoleucine involves muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis
    • M. Doi, I. Yamaoka, M. Nakayama, K. Sugahara, and F. Yoshizawa Hypoglycemic effect of isoleucine involves muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis Am J Physiol Endocrinol Metab 292 2007 E1683 E1693
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Doi, M.1    Yamaoka, I.2    Nakayama, M.3    Sugahara, K.4    Yoshizawa, F.5
  • 25
    • 0014818609 scopus 로고
    • The stimulation of insulin release by essential amino acids from rabbit pancreas in vitro
    • R.D. Milner The stimulation of insulin release by essential amino acids from rabbit pancreas in vitro J Endocrinol 47 1970 347 356
    • (1970) J Endocrinol , vol.47 , pp. 347-356
    • Milner, R.D.1
  • 26
    • 66349111734 scopus 로고    scopus 로고
    • Criteria for evaluation of novel markers of cardiovascular risk: A scientific statement from the American Heart Association
    • A.H. Mark, G. Philip, and K.A. Donna Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association Circulation 119 2009 2408 2416
    • (2009) Circulation , vol.119 , pp. 2408-2416
    • Mark, A.H.1    Philip, G.2    Donna, K.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.