Supratentorial neurometabolic alterations in pediatric survivors of posterior fossa tumors

International Journal of Radiation Oncology Biology Physics

Volumn 82, Issue 3, 2012, Pages 1135-1141

  Rueckriegel, Stefan M ^a   Driever, Pablo Hernáiz ^a   Bruhn, Harald ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

Medulloblastoma; MR proton spectroscopy; Neurometabolism; Pilocytic astrocytoma; Sequelae

Indexed keywords

ASTROCYTOMA; MEDULLOBLASTOMA; MR PROTON; NEUROMETABOLISM; SEQUELAE;

BRAIN; CHEMOTHERAPY; IRRADIATION; MAGNETIC RESONANCE SPECTROSCOPY; METABOLISM; METABOLITES; PEDIATRICS; TUMORS;

PATIENT TREATMENT;

CARBOPLATIN; CREATINE; CYCLOPHOSPHAMIDE; ETOPOSIDE; LOMUSTINE; METHOTREXATE; N ACETYLASPARTIC ACID; VINCRISTINE;

ADOLESCENT; ADULT; ARTICLE; BRAIN METABOLISM; BRAIN RADIATION; CANCER SURVIVOR; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; MALE; MEDULLOBLASTOMA; METABOLITE; NEUROMETABOLISM; PARIETAL LOBE; PILOCYTIC ASTROCYTOMA; POSTERIOR CRANIAL FOSSA TUMOR; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHOOL CHILD; WHITE MATTER; WORLD HEALTH ORGANIZATION;

ADOLESCENT; ADULT; AGE FACTORS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASPARTIC ACID; ASTROCYTOMA; BRAIN; CASE-CONTROL STUDIES; CEREBELLAR NEOPLASMS; CHEMORADIOTHERAPY; CHILD; CHILD, PRESCHOOL; CREATINE; FEMALE; HUMANS; INFANT; INFRATENTORIAL NEOPLASMS; LEUKOENCEPHALOPATHIES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEDULLOBLASTOMA; PHOSPHOCREATINE; SEX FACTORS; YOUNG ADULT;

EID: 84856378357     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.04.017     Document Type: Article

References (44)

1. R.K. Mulhern, T.E. Merchant, and A. Gajjar Late neurocognitive sequelae in survivors of brain tumours in childhood Lancet Oncol 5 2004 399 408
2. D. Qiu, D.L. Kwong, and G.C. Chan Diffusion tensor magnetic resonance imaging finding of discrepant fractional anisotropy between the frontal and parietal lobes after whole-brain irradiation in childhood medulloblastoma survivors: Reflection of regional white matter radiosensitivity? Int J Radiat Oncol Biol Phys 69 2007 846 851
3. T.E. Schultheiss, L.E. Kun, K.K. Ang, and L.C. Stephens Radiation response of the central nervous system Int J Radiat Oncol Biol Phys 31 1995 1093 1112
4. J. Grill, V.K. Renaux, and C. Bulteau Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes Int J Radiat Oncol Biol Phys 45 1999 137 145
5. S.L. Palmer, W.E. Reddick, and A. Gajjar Understanding the cognitive impact on children who are treated for medulloblastoma J Pediatr Psychol 32 2007 1040 1049
6. C. Ronning, K. Sundet, and B. Due-Tonnessen Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood Pediatr Neurosurg 41 2005 15 21
7. E.A. Quintero-Gallego, C.M. Gomez, and E. Vaquero Casares Declarative and procedural learning in children and adolescents with posterior fossa tumours Behav Brain Funct 2 2006 9
8. E. Vaquero, C.M. Gomez, and E.A. Quintero Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor Behav Brain Funct 4 2008 18
9. L.S. Constine, A. Konski, and S. Ekholm Adverse effects of brain irradiation correlated with MR and CT imaging Int J Radiat Oncol Biol Phys 15 1988 319 330
10. W.E. Reddick, Z.Y. Shan, and J.O. Glass Smaller white-matter volumes are associated with larger deficits in attention and learning among long-term survivors of acute lymphoblastic leukemia Cancer 106 2006 941 949
11. R.K. Mulhern, S.L. Palmer, and W.E. Reddick Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss J Clin Oncol 19 2001 472 479
12. W.E. Reddick, H.A. White, and J.O. Glass Developmental model relating white matter volume to neurocognitive deficits in pediatric brain tumor survivors Cancer 97 2003 2512 2519
13. S.M. Rueckriegel, P.H. Driever, and F. Blankenburg Differences in supratentorial damage of white matter in pediatric survivors of posterior fossa tumors with and without adjuvant treatment as detected by magnetic resonance diffusion tensor imaging Int J Radiat Oncol Biol Phys 76 2010 859 866
14. T. Michaelis, K.D. Merboldt, and H. Bruhn Absolute concentrations of metabolites in the adult human brain in vivo: Quantification of localized proton MR spectra Radiology 187 1993 219 227
15. B. Ross, and S. Bluml Magnetic resonance spectroscopy of the human brain Anat Rec 265 2001 54 84
16. J.R. Moffett, B. Ross, and P. Arun N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology Prog Neurobiol 81 2007 89 131
17. S.M. Waldrop, P.C. Davis, and C.A. Padgett Treatment of brain tumors in children is associated with abnormal MR spectroscopic ratios in brain tissue remote from the tumor site AJNR Am J Neuroradiol 19 1998 963 970
18. A. Trotti, A.D. Colevas, and A. Setser CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment Semin Radiat Oncol 13 2003 176 181
19. S.J. Kellie, J. Chaku, and L.R. Lockwood Late magnetic resonance imaging features of leukoencephalopathy in children with central nervous system tumours following high-dose methotrexate and neuraxis radiation therapy Eur J Cancer 41 2005 1588 1596
20. Bottomley PA, inventor. iGEa: Selective volume method for performing localized NMR spectroscopy. US patent 4,480,228. 1984 October 30.
21. P.G. Webb, N. Sailasuta, and S.J. Kohler Automated single-voxel proton MRS: Technical development and multisite verification Magn Reson Med 31 1994 365 373
22. S.W. Provencher Estimation of metabolite concentrations from localized in vivo proton NMR spectra Magn Reson Med 30 1993 672 679
23. T.E. Inder, and P.S. Huppi In vivo studies of brain development by magnetic resonance techniques Ment Retard Dev Disabil Res Rev 6 2000 59 67
24. C.J. Peden, F.M. Cowan, and D.J. Bryant Proton MR spectroscopy of the brain in infants J Comput Assist Tomogr 14 1990 886 894
25. P.S. Huppi, C. Fusch, and C. Boesch Regional metabolic assessment of human brain during development by proton magnetic resonance spectroscopy in vivo and by high-performance liquid chromatography/gas chromatography in autopsy tissue Pediatr Res 37 1995 145 150
26. M.S. van der Knaap, J. van der Grond, and P.C. van Rijen Age-dependent changes in localized proton and phosphorus MR spectroscopy of the brain Radiology 176 1990 509 515
27. P.J. Pouwels, K. Brockmann, and B. Kruse Regional age dependence of human brain metabolites from infancy to adulthood as detected by quantitative localized proton MRS Pediatr Res 46 1999 474 485
28. S.M. Rueckriegel, F. Blankenburg, and R. Burghardt Influence of age and movement complexity on kinematic hand movement parameters in childhood and adolescence Int J Dev Neurosci 26 2008 655 663
29. K. Muller, V. Homberg, and H.G. Lenard Magnetic stimulation of motor cortex and nerve roots in children. Maturation of cortico-motoneuronal projections Electroencephalogr Clin Neurophysiol 81 1991 63 70
30. T. Kaminaga, and K. Shirai Radiation-induced brain metabolic changes in the acute and early delayed phase detected with quantitative proton magnetic resonance spectroscopy J Comput Assist Tomogr 29 2005 293 297
31. S.J. Qiu, X.L. Zhang, Y. Zhang, and M. Jiang Proton magnetic resonance spectroscopy for radiation encephalopathy induced by radiotherapy for nasopharyngeal carcinoma Nan Fang Yi Ke Da Xue Xue Bao 27 2007 241 246
32. W.C. Chu, K.W. Chik, and Y.L. Chan White matter and cerebral metabolite changes in children undergoing treatment for acute lymphoblastic leukemia: Longitudinal study with MR imaging and 1H MR spectroscopy Radiology 229 2003 659 669
33. T. Usenius, J.P. Usenius, and M. Tenhunen Radiation-induced changes in human brain metabolites as studied by 1H nuclear magnetic resonance spectroscopy in vivo Int J Radiat Oncol Biol Phys 33 1995 719 724
34. M. Hajek, M. Dezortova, and R. Liscak 1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife Eur Radiol 13 2003 994 1000
35. B. Movsas, B.S. Li, and J.S. Babb Quantifying radiation therapy-induced brain injury with whole-brain proton MR spectroscopy: Initial observations Radiology 221 2001 327 331
36. Y.L. Chan, D.K. Yeung, S.F. Leung, and G. Cao Proton magnetic resonance spectroscopy of late delayed radiation-induced injury of the brain J Magn Reson Imaging 10 1999 130 137
37. Y.L. Chan, D.J. Roebuck, and M.P. Yuen Long-term cerebral metabolite changes on proton magnetic resonance spectroscopy in patients cured of acute lymphoblastic leukemia with previous intrathecal methotrexate and cranial irradiation prophylaxis Int J Radiat Oncol Biol Phys 50 2001 759 763
38. I.J. Barani, S.H. Benedict, and P.S. Lin Neural stem cells: Implications for the conventional radiotherapy of central nervous system malignancies Int J Radiat Oncol Biol Phys 68 2007 324 333
39. N.A. Hellstrom, T. Bjork-Eriksson, K. Blomgren, and H.G. Kuhn Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation Stem Cells 27 2009 634 641
40. A. Davidson, D.M. Tait, and G.S. Payne Magnetic resonance spectroscopy in the evaluation of neurotoxicity following cranial irradiation for childhood cancer Br J Radiol 73 2000 421 424
41. A. Davidson, G. Payne, and M.O. Leach Proton magnetic resonance spectroscopy ((1)H-MRS) of the brain following high-dose methotrexate treatment for childhood cancer Med Pediatr Oncol 35 2000 28 34
42. E.A. Steffen-Smith, P.L. Wolters, and P.S. Albert Detection and characterization of neurotoxicity in cancer patients using proton MR spectroscopy Childs Nerv Syst 24 2008 807 813
43. S.M. Rueckriegel, F. Blankenburg, and G. Henze Loss of fine motor function correlates with ataxia and decline of cognition in cerebellar tumor survivors Pediatr Blood Cancer 53 2009 424 431
44. L. Chang, C.S. Jiang, and T. Ernst Effects of age and sex on brain glutamate and other metabolites Magn Reson Imag 27 2009 142 145