The Pseudomonas aeruginosa toxin L-2-amino-4-methoxy-trans-3-butenoic acid inhibits growth and induces encystment in Acanthamoeba castellanii

Microbes and Infection

Volumn 14, Issue 3, 2012, Pages 268-272

  Lee, Xiaoyun ^a   Reimmann, Cornelia ^a   Greub, Gilbert ^a   Sufrin, Janice ^b   Croxatto, Antony ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

2 Amino 4 methoxy 3 butenoic acid; Acanthamoeba castellanii; Antimetabolite; Pseudomonas aeruginosa; Vinylglycine

Indexed keywords

2 AMINO 4 METHOXY 3 BUTENOIC ACID; ANTIMETABOLITE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ACANTHAMOEBA CASTELLANII; AMOEBA (LIFE CYCLE STAGE); ANTIBIOTIC RESISTANCE; ANTIPROTOZOAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYST (RESTING STAGE); IMMUNE RESPONSE; MICROBIAL GROWTH; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

ACANTHAMOEBA CASTELLANII; AMINOBUTYRIC ACIDS; BACTERIAL TOXINS; BUFFERS; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCINE; MICROBIAL VIABILITY; PSEUDOMONAS AERUGINOSA; STAINING AND LABELING; TROPHOZOITES; TRYPAN BLUE; VIRULENCE FACTORS;

ACANTHAMOEBA CASTELLANII; BACTERIA (MICROORGANISMS); PSEUDOMONAS AERUGINOSA;

EID: 84856344525     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2011.10.004     Document Type: Article

References (24)

1. Döring G. Pseudomonas aeruginosa lung infection in cystic fibrosis patients. Pseudomonas aeruginosa as an Opportunistic Pathogen 1993, 245-273. Plenum Press, New York. M. Campa, M. Bendinelli, H. Friedman (Eds.).
2. D'Argenio D.A. The pathogenic lifestyle of Pseudomonas aeruginosa in model systems of virulence. Pseudomonas 2004, Vol 1:477-503. Kluwer Academic, Plenum Publishers, New York. J.-L. Ramos (Ed.).
3. Sahm U., Knobloch G., Wagner F. Isolation and characterization of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid from Pseudomonas aeruginosa grown on n-paraffin. J. Antibiot. 1973, 26:389-390.
4. Scannell J.P., Pruess D.L., Demny T.C., Sello L.H., Williams T., Stempel A. Antimetabolites produced by microorganisms. V. L-2-amino-4-methoxy-trans-3-butenoic acid. J. Antibiot. 1972, 25:122-127.
5. Tisdale M.J. The effect of the methionine antagonist L-2-amino-4-methoxy-trans-3-butenoic acid on the growth and metabolism of walker carcinosarcoma invitro. Biochem. Pharmacol. 1980, 29:501-508.
6. Berkowitz D.A., Charette B.D., Karukurichi K.R., McFadden J.M. α-Vinylic amino acids: occurrence, asymmetric synthesis, and biochemical mechanisms. Tetrahedron: Asymmetry 2006, 17:869-882.
7. McPhail K.L., Armstrong D.J., Azevedo M.D., Banowetz G.M., Mills D.I. 4-Formylaminooxyvinylglycine, an herbicidal germination-arrest factor from Pseudomonas rhizosphere bacteria. J. Nat. Prod. 2010, 73:1853-1857.
8. Lee X., Fox á, Sufrin J., Henry H., Majcherczyk P., Haas D., Reimmann C. Identification of the biosynthetic gene cluster for the Pseudomonas aeruginosa antimetabolite L-2-amino-4-methoxy-trans-3-butenoic acid. J. Bacteriol. 2010, 192:4251-4255.
9. Kurz C.E., Ewbank J.J. Infection in a dish: high-throughput analyses of bacterial pathogenesis. Curr. Opin. Microbiol. 2007, 10:10-16.
10. Lienard J., Greub G. Discovering new pathogens: amoebae as tools to isolate amoeba-resisting microorganisms from environmental samples. Environmental Microbiology 2011, 143-162. Current Technology and Water Applications, Norfolk, UK. K. Sen, N.J. Ashbolt (Eds.).
11. Arndt J., Schmidt-Denter K., Auer B., Weitere M. Biofilms and protozoans. Fossil and Recent Biofilms, Mats and Networks 2003, 173-189. Kluwer Academic Publishers, Dordrecht. W.E. Krumbein, D.M. Paterson, G.A. Zavarzin (Eds.).
12. Cordingley J.S., Wills R.A., Willemez C.L. Osmolarity is an independent trigger of Acanthamoeba castellanii differentiation. J. Cell. Biochem. 1996, 61:167-171.
13. McClellan K., Howard K., Mayhew E., Niederkorn J., Alizadeh H. Adaptive immune responses to Acanthamoeba cysts. Exp. Eye Res. 2002, 75:285-293.
14. Rowbotham T.J. Isolation of Legionella pneumophila from clinical specimens via amoebae, and the interaction of those and other isolates with amoebae. Clin. Pathol. 1983, 36:978-986.
15. Pearson J.P., Pesci E.C., Iglewski B.H. Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J. Bacteriol. 1997, 179:5756-5767.
16. Alks V., Sufrin J.R. Improved synthetic access to the β,γ-enol ether amino acids, L-2-amino-4-methoxy-trans-but-3-enoic acid and L-2-amino-4-methoxy-cis-but-3-enoic acid. Tetrahedron Lett. 1990, 31:5257-5260.
17. Froquet R., Lelong E., Marchetti A., Cosson P. Dictyostelium discoideum: a model host to measure bacterial virulence. Nat. Protoc. 2009, 4:25-30.
18. Cosson P., Zulianello L., Join-Lambert O., Faurisson F., Gebbie L., Benghezal M., Van Delden C., Curty L.K., Köhler T. Pseudomonas aeruginosa virulence analyzed in a Dictyostelium discoideum host system. J. Bacteriol. 2002, 184:3027-3033.
19. Molmeret M., Horn M., Wagner M., Santic M., Abu Kwaik Y. Amoebae as training grounds for intracellular bacterial pathogens. Appl. Environ. Microbiol. 2005, 71:20-28.
20. Weber S.S., Ragaz C., Hilbi H. The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE. Cell. Microbiol. 2009, 11:442-460.
21. Seeger E.M., Thuma M., Fernandez-Moreira E., Jacobs E., Schmitz M., Helbig J.H. Lipopolysaccharide of Legionella pneumophila shed in a liquid culture as a nonvesicular fraction arrests phagosome maturation in amoeba and monocytic host cells. FEMS Microbiol. Lett. 2010, 307:113-119.
22. Segal G., Shuman H.A. Legionella pneumophila utilizes the same genes to multiply within Acanthamoeba castellanii and human macrophages. Infect. Immun. 1999, 67:2117-2124.
23. Kim E.H., Charpentier X., Torres-Urquidy O., McEvoy M.M., Rensing C. The metal efflux island of Legionella pneumophila is not required for survival in macrophages and amoebas. FEMS Microbiol. Lett. 2009, 301:164-170.
24. Alibaud L., Köhler T., Coudray A., Prigent-Combaret C., Bergeret E., Perrin J., Benghezal M., Reimmann C., Gauthier Y., van Delden C., Attree I., Fauvarque M.O., Cosson P. Pseudomonas aeruginosa virulence genes identified in a Dictyostelium host model. Cell. Microbiol. 2008, 10:729-740.