Pseudomonas aeruginosa virulence genes identified in a Dictyostelium host model

Cellular Microbiology

Volumn 10, Issue 3, 2008, Pages 729-740

  Alibaud, Laeticia ^a   Köhler, Thilo ^a,b   Coudray, Alice ^a   Prigent Combaret, Claire ^a   Bergeret, Evelyne ^c,d,e   Perrin, Jackie ^c,d,e   Benghezal, Mohammed ^a   Reimmann, Cornelia ^f   Gauthier, Yves ^g   Van Delden, Christian ^a,b   Attree, Ina ^h   Fauvarque, Marie Odile ^c,d,e   Cosson, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c CEA GRENOBLE   (France)

^d INSERM   (France)

^e UniversitéJoseph Fourier ^*  (France)

^f Centre de Recherche du Service de Santédes Armées   (France)

^g UNIVERSITY OF LAUSANNE   (Switzerland)

^h DIF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN PCHH; PROTEIN PCHL; PROTEIN TRPD; RHAMNOLIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL PNEUMONIA; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; DICTYOSTELIUM; DROSOPHILA; FEMALE; GENE IDENTIFICATION; GENE INDUCTION; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; TYPE III SECRETION SYSTEM;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; DICTYOSTELIUM; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA; FEMALE; HUMANS; MALE; MICE; MUTAGENESIS, INSERTIONAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SURVIVAL ANALYSIS; VIRULENCE; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); DICTYOSTELIUM; MAMMALIA; MUS; PSEUDOMONAS AERUGINOSA;

EID: 38849188460     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2007.01080.x     Document Type: Article

References (48)

1. Bazire, A., Dheilly, A., Diab, F., Morin, D., Jebbar, M., Haras, D., and Dufour, A. (2005) Osmotic stress and phosphate limitation alter production of cell-to-cell signal molecules and rhamnolipid biosurfactant by Pseudomonas aeruginosa. FEMS Microbiol Lett 253: 125-131.
2. Benghezal, M., Fauvarque, M.O., Tournebize, R., Froquet, R., Marchetti, A., Bergeret, E., et al. (2006) Specific host genes required for the killing of Klebsiella bacteria by phagocytes. Cell Microbiol 8: 139-148.
3. Caterina, M.J., Milne, J.L., and Devreotes, P.N. (1994) Mutation of the third intracellular loop of the cAMP receptor, cAR1, of Dictyostelium yields mutants impaired in multiple signaling pathways. J Biol Chem 269: 1523-1532.
4. Chandrasekaran, E.V., and Bemiller, J.N. (1980) Constituent analysis of glycosaminoglycans. In Methods in Carbohydrate Chemistry. Whistler, R.L. (ed.). New York: Academic Press, pp. 89-96.
5. Cornillon, S., Olie, R.A., and Golstein, P. (1998) An insertional mutagenesis approach to Dictyostelium cell death. Cell Death Differ 5: 416-425.
6. Cornillon, S., Pech, E., Benghezal, M., Ravanel, K., Gaynor, E., Letourneur, F., et al. (2000) Phg1p is a nine-transmembrane protein superfamily member involved in dictyostelium adhesion and phagocytosis. J Biol Chem 275: 34287-34292.
7. Cosson, P., Zulianello, L., Join-Lambert, O., Faurisson, F., Gebbie, L., Benghezal, M., et al. (2002) Pseudomonas aeruginosa virulence analyzed in a Dictyostelium discoideum host system. J Bacteriol 184: 3027-3033.
8. D'Argenio, D.A., Gallagher, L.A., Berg, C.A., and Manoil, C. (2001) Drosophila as a model host for Pseudomonas aeruginosa infection. J Bacteriol 183: 1466-1471.
9. D'Argenio, D.A., Wu, M., Hoffman, L.R., Kulasekara, H.D., Deziel, E., Smith, E.E., et al. (2007) Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Mol Microbiol 64: 512-533.
10. Dacheux, D., Attree, I., Schneider, C., and Toussaint, B. (1999) Cell death of human polymorphonuclear neutrophils induced by a Pseudomonas aeruginosa cystic fibrosis isolate requires a functional type III secretion system. Infect Immun 67: 6164-6167.
11. van Delden, C., Comte, R., and Bally, A.M. (2001) Stringent response activates quorum sensing and modulates cell density-dependent gene expression in Pseudomonas aeruginosa. J Bacteriol 183: 5376-5384.
12. Denervaud, V., TuQuoc, P., Blanc, D., Favre-Bonte, S., Krishnapillai, V., Reimmann, C., et al. (2004) Characterization of cell-to-cell signaling-deficient Pseudomonas aeruginosa strains colonizing intubated patients. J Clin Microbiol 42: 554-562.
13. Dumas, J.L., van Delden, C., Perron, K., and Kohler, T. (2006) Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR. FEMS Microbiol Lett 254: 217-225.
14. Erickson, D.L., Lines, J.L., Pesci, E.C., Venturi, V., and Storey, D.G. (2004) Pseudomonas aeruginosa relA contributes to virulence in Drosophila melanogaster. Infect Immun 72: 5638-5645.
15. Essar, D.W., Eberly, L., Han, C.Y., and Crawford, I.P. (1990) DNA sequences and characterization of four early genes of the tryptophan pathway in Pseudomonas aeruginosa. J Bacteriol 172: 853-866.
16. Fauvarque, M.O., Bergeret, E., Chabert, J., Dacheux, D., Satre, M., and Attree, I. (2002) Role and activation of type III secretion system genes in Pseudomonas aeruginosa -induced Drosophila killing. Microb Pathog 32: 287-295.
17. Froquet, R., Cherix, N., Burr, S., Frey, J., Vilches, S., Tomas, J.M., and Cosson, P. (2007) An alternative host model to evaluate Aeromonas virulence. Appl Environ Microbiol 73: 5657-5659.
18. Hilbi, H., Weber, S.S., Ragaz, C., Nyfeler, Y., and Urwyler, S. (2007) Environmental predators as models for bacterial pathogenesis. Environ Microbiol 9: 563-575.
19. Latifi, A., Foglino, M., Tanaka, K., Williams, P., and Lazdunski, A. (1996) A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS. Mol Microbiol 21: 1137-1146.
20. de Lorenzo, V., Herrero, M., Jakubzik, U., and Timmis, K.N. (1990) Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria. J Bacteriol 172: 6568-6572.
21. Lyczak, J.B., Cannon, C.L., and Pier, G.B. (2000) Establishment of Pseudomonas aeruginosa infection: Lessons from a versatile opportunist. Microbes Infect 2: 1051-1060.
22. McKnight, S.L., Iglewski, B.H., and Pesci, E.C. (2000) The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 182: 2702-2708.
23. Mei, J.M., Nourbakhsh, F., Ford, C.W., and Holden, D.W. (1997) Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis. Mol Microbiol 26: 399-407.
24. Moffett, J.R., and Namboodiri, M.A. (2003) Tryptophan and the immune response. Immunol Cell Biol 81: 247-265.
25. Morgan, A.F. (1979) Transduction of Pseudomonas aeruginosa with a mutant of bacteriophage E79. J Bacteriol 139: 137-140.
26. Ochsner, U.A., Koch, A.K., Fiechter, A., and Reiser, J. (1994) Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. J Bacteriol 176: 2044-2054.
27. Pesci, E.C., Milbank, J.B., Pearson, J.P., McKnight, S., Kende, A.S., Greenberg, E.P., and Iglewski, B.H. (1999) Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci USA 96: 11229-11234.
28. Pesci, E.C., Pearson, J.P., Seed, P.C., and Iglewski, B.H. (1997) Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 179: 3127-3132.
29. Pukatzki, S., Kessin, R.H., and Mekalanos, J.J. (2002) The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideum. Proc Natl Acad Sci USA 99: 3159-3164.
30. Rahme, L.G., Ausubel, F.M., Cao, H., Drenkard, E., Goumnerov, B.C., Lau, G.W., et al. (2000) Plants and animals share functionally common bacterial virulence factors. Proc Natl Acad Sci USA 97: 8815-8821.
31. Rahme, L.G., Tan, M.W., Le, L., Wong, S.M., Tompkins, R.G., Calderwood, S.B., and Ausubel, F.M. (1997) Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci USA 94: 13245-13250.
32. Reimmann, C., Patel, H.M., Serino, L., Barone, M., Walsh, C.T., and Haas, D. (2001) Essential PchG-dependent reduction in pyochelin biosynthesis of Pseudomonas aeruginosa. J Bacteriol 183: 813-820.
33. Reimmann, C., Serino, L., Beyeler, M., and Haas, D. (1998) Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa. Microbiology 144 (Part 11): 3135-3148.
34. Roy-Burman, A., Savel, R.H., Racine, S., Swanson, B.L., Revadigar, N.S., Fujimoto, J., et al. (2001) Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections. J Infect Dis 183: 1767-1774.
35. Rumbaugh, K.P., Griswold, J.A., and Hamood, A.N. (2000) The role of quorum sensing in the in vivo virulence of Pseudomonas aeruginosa. Microbes Infect 2: 1721-1731.
36. Serino, L., Reimmann, C., Visca, P., Beyeler, M., Chiesa, V.D., and Haas, D. (1997) Biosynthesis of pyochelin and dihydroaeruginoic acid requires the iron-regulated pchDCBA operon in Pseudomonas aeruginosa. J Bacteriol 179: 248-257.
37. Sifri, C.D., Begun, J., and Ausubel, F.M. (2005) The worm has turned -microbial virulence modeled in Caenorhabditis elegans. Trends Microbiol 13: 119-127.
38. Smith, D.A., Parish, T., Stoker, N.G., and Bancroft, G.J. (2001) Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates. Infect Immun 69: 1142-1150.
39. Soberon-Chavez, G., Aguirre-Ramirez, M., and Ordonez, L. (2005) Is Pseudomonas aeruginosa only 'sensing quorum'? Crit Rev Microbiol 31: 171-182.
40. Switzer, R.C., 3rd, Merril, C.R., and Shifrin, S. (1979) A highly sensitive silver stain for detecting proteins and peptides in polyacrylamide gels. Anal Biochem 98: 231-237.
41. Van Delden, C., and Iglewski, B.H. (1998) Cell-to-cell signaling and Pseudomonas aeruginosa infections. Emerg Infect Dis 4: 551-560.
42. Vodovar, N., Acosta, C., Lemaitre, B., and Boccard, F. (2004) Drosophila: A polyvalent model to decipher host-pathogen interactions. Trends Microbiol 12: 235-242.
43. Vodovar, N., Vinals, M., Liehl, P., Basset, A., Degrouard, J., Spellman, P., et al. (2005) Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species. Proc Natl Acad Sci USA 102: 11414-11419.
44. Wade, D.S., Calfee, M.W., Rocha, E.R., Ling, E.A., Engstrom, E., Coleman, J.P., and Pesci, E.C. (2005) Regulation of Pseudomonas quinolone signal synthesis in Pseudomonas aeruginosa. J Bacteriol 187: 4372-4380.
45. Watson, A.A., Alm, R.A., and Mattick, J.S. (1996) Construction of improved vectors for protein production in Pseudomonas aeruginosa. Gene 172: 163-164.
46. Yahr, T.L., Mende-Mueller, L.M., Friese, M.B., and Frank, D.W. (1997) Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon. J Bacteriol 179: 7165-7168.
47. Yahr, T.L., and Wolfgang, M.C. (2006) Transcriptional regulation of the Pseudomonas aeruginosa type III secretion system. Mol Microbiol 62: 631-640.
48. Zulianello, L., Canard, C., Kohler, T., Caille, D., Lacroix, J.S., and Meda, P. (2006) Rhamnolipids are virulence factors that promote early infiltration of primary human airway epithelia by Pseudomonas aeruginosa. Infect Immun 74: 3134-3147.