Efficacy of blue light vs. red light in the treatment of psoriasis: A double-blind, randomized comparative study

Journal of the European Academy of Dermatology and Venereology

Volumn 26, Issue 2, 2012, Pages 219-225

  Kleinpenning, M M ^a   Otero, M E ^a   Van Erp, P E J ^a   Gerritsen, M J P ^a   Van De Kerkhof, P C M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PETROLATUM; SALICYLIC ACID;

ADULT; AGED; ARTICLE; BLUE LIGHT; CLINICAL ARTICLE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ERYTHEMA; FEMALE; HUMAN; HYPERPIGMENTATION; MALE; PHOTODYNAMIC THERAPY; PILOT STUDY; PRIORITY JOURNAL; PSORIASIS; RANDOMIZED CONTROLLED TRIAL; RED LIGHT; SKIN INDURATION; TREATMENT OUTCOME; XERODERMA;

ADULT; AGED; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LIGHT; MALE; MIDDLE AGED; PHOTOTHERAPY; PSORIASIS;

EID: 84856341210     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2011.04039.x     Document Type: Article

References (25)

1. Shnitkind E, Yaping E, Geen S, et al. Anti-inflammatory properties of narrow-band blue light. J Drugs Dermatol 2006; 5: 605-610.
2. Kjeldstad B, Johnsson A,. An action spectrum for blue and near ultraviolet inactivation of Propionibacterium acnes; with emphasis on a possible porphyrin photosensitization. Photochem Photobiol 2001; 43: 67-70.
3. Lipovsky A, Nitzan Y, Lubart R,. A possible mechanism for visible light-induced wound healing. Lasers Surg Med 2008; 40: 509-514.
4. Krutmann J, Hönigsmann H, Elmets C,. Dermatological Phototherapy and Photodiagnostic Methods, Vol. 1. Springer-Verlag, Heidelberg, 2001.
5. Collins P, Robinson DJ, Stringer MR, et al. The variable response of plaque psoriasis after a single treatment with topical 5-aminolaevulinic acid photodynamic therapy. Br J Dermatol 1997; 137: 743-749. (Pubitemid 27496191)
6. Stringer MR, Collins P, Robinson DJ, et al. The accumulation of protoporphyrin IX in plaque psoriasis after topical application of 5-aminolevulinic acid indicates a potential for superficial photodynamic therapy. J Invest Dermatol 1996; 107: 76-81. (Pubitemid 26236098)
7. Smits T, Kleinpenning MM, van Erp PE, et al. A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis. Br J Dermatol 2006; 155: 429-436. (Pubitemid 44050580)
8. Robinson DJ, Collins P, Stringer MR, et al. Improved response of plaque psoriasis after multiple treatments with topical 5-aminolaevulinic acid photodynamic therapy. Acta Derm Venereol 2001; 79: 451-455.
9. Boehncke WH, Konig K, Kaufmann R, et al. Photodynamic therapy in psoriasis: suppression of cytokine production in vitro and recording of fluorescence modification during treatment in vivo. Arch Dermatol Res 2001; 286: 300-303.
10. Boehncke WH, Sterry W, Kaufmann R,. Treatment of psoriasis by topical photodynamic therapy with polychromatic light. Lancet 2001; 343: 801.
11. Bissonnette R, Zeng H, McLean DI, et al. Psoriatic plaques exhibit red autofluorescence that is due to protoporphyrin IX. J Invest Dermatol 1998; 111: 586-591. (Pubitemid 28452317)
12. Liebmann J, Born M, Kolb-Bachofen V,. Blue-light irradiation regulates proliferation and differentiation in human skin cells. J Invest Dermatol 2010; 130: 259-269.
13. Fluhr JW, Cavallotti C, Berardesca E,. Emollients, moisturizers, and keratolytic agents in psoriasis. Clin Dermatol 2008; 26: 380-386.
14. Maari C, Viau G, Bissonnette R,. Repeated exposure to blue light does not improve psoriasis. J Am Acad Dermatol 2003; 49: 55-58. (Pubitemid 36801631)
15. Smits T, van Laarhoven AIM, Staassen A, van de Kerkhof PCM, van Erp PEJ, Gerritsen MJP,. Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells. Br J Dermatol 2009; 160: 849-857.
16. Ibbotson SH, Jong C, Lesar A, et al. Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo. Photodermatol Photoimmunol Photomed 2006; 22: 105-110. (Pubitemid 44056529)
17. Karu T,. Primary and secondary mechanisms of action of visible to near-IR radiation on cells. J Photochem Photobiol B 2001; 49: 1-17. (Pubitemid 29229670)
18. Stadler I, Evans R, Kolb B, et al. In vitro effects of low-level laser irradiation at 660 nm on peripheral blood lymphocytes. Lasers Surg Med 2000; 27: 255-261.
19. El-Ghorr AA, Norval M,. Biological effects of narrow-band (311 nm TL01) UVB irradiation: a review. J Photochem Photobiol B 1997; 38: 99-106. (Pubitemid 27277864)
20. Hamilton FL, Car J, Lyons C, Car M, Layton A, Majeed A,. Laser and other light therapies for the treatment of acne vulgaris: systematic review. Br J Dermatol 2009; 160: 1273-1285.
21. Lee SY, You CE, Park MY,. Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV. Lasers Surg Med 2007; 39: 180-188. (Pubitemid 46411414)
22. Pathak MA, RILEY FJ, Fitzpatrick TB, et al. Melanin formation in human skin induced by long-wave ultra-violet and visible light. Nature 1962; 193: 148-150.
23. Porges SB, Kaidbey KH, Grove GL,. Quantification of visible light-induced melanogenesis in human skin. Photodermatology 1988; 5: 197-200. (Pubitemid 19026800)
24. Kleinpenning MM, Smits T, Frunt MH, et al. Clinical and histological effects of blue light on normal skin. Photodermatol Photoimmunol Photomed 2010; 26: 16-21.
25. Kirke SM, Lowder S, Lloyd JJ, et al. A randomized comparison of selective broadband UVB and narrowband UVB in the treatment of psoriasis. J Invest Dermatol 2007; 127: 1641-1646. (Pubitemid 46933429)