Silencing of P2Y 2 receptors reduces intraocular pressure in New Zealand rabbits

British Journal of Pharmacology

Volumn 165, Issue 4 B, 2012, Pages 1163-1172

  Martin Gil, Alba ^a   De Lara, María Jesús Perez ^a   Crooke, Almudena ^a   Santano, Concepciõn ^a   Peral, Assumpta ^a   Pintor, Jesus ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

eye; glaucoma; intraocular pressure; P2Y 2 receptor; siRNA; uridine nucleotides

Indexed keywords

2 THIOURIDINE 5' TRIPHOSPHATE; 2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; CIBACRON BLUE F3GA; COMPLEMENTARY DNA; MRS 2578; NUCLEOTIDE; PURINERGIC P2Y1 RECEPTOR ANTAGONIST; PURINERGIC P2Y2 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RECEPTOR BLOCKING AGENT; SMALL INTERFERING RNA; SURAMIN; UNCLASSIFIED DRUG; URIDINE 5'(GAMMA THIO) TRIPHOSPHATE; URIDINE DERIVATIVE; URIDINE TRIPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CILIARY BODY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FOLLOW UP; GENE AMPLIFICATION; GENE SILENCING; GLAUCOMA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; RAPID AMPLIFICATION OF CDNA ENDS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS; SINGLE DRUG DOSE;

AMINO ACID SEQUENCE; ANIMALS; GENE SILENCING; INTRAOCULAR PRESSURE; MALE; MOLECULAR SEQUENCE DATA; OCULAR HYPERTENSION; PURINERGIC P2Y RECEPTOR AGONISTS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RABBITS; RECEPTORS, PURINERGIC P2Y2; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA; THIONUCLEOTIDES; URIDINE TRIPHOSPHATE;

EID: 84856324600     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01586.x     Document Type: Article

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