Sensorimotor gating and clinical outcome following cognitive behaviour therapy for psychosis

Schizophrenia Research

Volumn 134, Issue 2-3, 2012, Pages 232-238

  Kumari, Veena ^a,b   Premkumar, Preethi ^a,c   Fannon, Dominic ^a   Aasen, Ingrid ^a   Raghuvanshi, Satya ^d   Anilkumar, Anantha P ^b   Antonova, Elena ^a   Peters, Emmanuelle R ^a,b   Kuipers, Elizabeth ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

^c NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Antipsychotics; Medication resistance; Prepulse inhibition; Schizophrenia; Startle; Symptoms

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; NEUROLEPTIC AGENT;

ADULT; ARTICLE; COGNITION; COGNITIVE THERAPY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; OUTPATIENT CARE; PARANOID SCHIZOPHRENIA; PREPULSE INHIBITION; PRIORITY JOURNAL; PSYCHOSIS; SCHIZOAFFECTIVE PSYCHOSIS; SENSORY GATING; SYMPTOM;

ACOUSTIC STIMULATION; ADULT; ANALYSIS OF VARIANCE; ANTIPSYCHOTIC AGENTS; CASE-CONTROL STUDIES; COGNITIVE THERAPY; COHORT STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; SENSORY GATING; TREATMENT OUTCOME;

EID: 84856295485     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2011.11.020     Document Type: Article

References (65)

1. Antonova E., Sharma T., Morris R., Kumari V. The relationship between brain structure and neurocognition in schizophrenia: a selective review. Schizophr. Res. 2004, 70(2-3):117-145.
2. Bellebaum C., Daum I. Cerebellar involvement in executive control. Cerebellum 2007, 6:184-192.
3. Bitsios P., Giakoumaki S.G. Relationship of prepulse inhibition of the startle reflex to attentional and executive mechanisms in man. Int. J. Psychophysiol. 2005, 55(2):229-241.
4. Bitsios P., Giakoumaki S.G., Theou K., Frangou S. Increased prepulse inhibition of the acoustic startle response is associated with better strategy formation and execution times in healthy males. Neuropsychologia 2006, 44(12):2494-2499.
5. Bluementhal T.D. Short lead interval startle modification. Startle Modification: Implications for Neuroscience, Cognitive Science and Clinical Science 1999, 51-77. Cambridge University Press, Cambridge. M.E. Dawson, A.M. Schell, A.H. Böhmelt (Eds.).
6. Brabban A., Tai S., Turkington D. Predictors of outcome in brief cognitive behavior therapy for schizophrenia. Schizophr. Bull. 2009, 35(5):859-864.
7. Braff D.L., Stone C., Callaway E., Geyer M., Glick I., Bali L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology 1978, 15:339-343.
8. Braff D.L., Grillon C., Geyer M.A. Gating and habituation of the startle reflex in schizophrenic patients. Arch. Gen. Psychiatry 1992, 49(3):206-215.
9. Braff D.L., Geyer M.A., Swerdlow N.R. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology 2001, 156(2-3):234-258.
10. Butler R.W., Jenkins M.A., Geyer M.A., Braff D.L. Wisconsin Card Sorting deficits and diminished sensorimotor gating in a discrete subgroup of schizophrenic patients. Schizophrenia Research: Advances in Neuropsychiatry and Psychopharmacology 1991, vol. 1:163-168. Raven Press, New York. C.A. Tamminga, S.C. Schulz (Eds.).
11. Conley R.R., Kelly D.L. Management of treatment resistance in schizophrenia. Biol. Psychiatry 2001, 50:898-911.
12. Dawson M.E., Schell A.M., Swerdlow N.R., Filion D.L. Cognitive, clinical, and neuropsychological implications of startle modulation. Attention and Orienting: Sensory and Motivational Processes 1997, 257-279. Lawrence Erlbaum Associates, NJ. P. Lang, R. Simons, M. Balaban, N. Mahwah (Eds.).
13. Dixon L.B., Dickerson F., Bellack A.S., Bennett M., Dickinson D., Goldberg R.W., Lehman A., Tenhula W.N., Calmes C., Pasillas R.M., Peer J., Kreyenbuhl J. The 2009 schizophrenia PORT psychosocial treatment recommendations and summary statements. Schizophr. Bull. 2010, 36(1):48-70.
14. Filion D.L., Poje A.B. Selective and nonselective attention effects on prepulse inhibition of startle: a comparison of task and no-task protocols. Biol. Psychol. 2003, 64:283-296.
15. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV-TR Axis I Disorders - Patient Edition (SCID-I/P, 11/2002 revision) 2002, Biometrics Research Department New York, NY.
16. Fowler D., Garety P., Kuipers E. Cognitive Behaviour Therapy for Psychosis: Theory and Practice 1995, Wiley Chichester.
17. Garety P.A., Fowler D., Kuipers E., Freeman D., Dunn G., Bebbington P., Hadley C., Jones S. London-East Anglia randomised controlled trial of cognitive-behavioural therapy for psychosis. II: predictors of outcome. Br. J. Psychiatry 1997, 171:420-426.
18. Geyer M.A. The family of sensorimotor gating disorders: comorbidities or diagnostic overlaps?. Neurotox. Res. 2006, 10(3-4):211-220.
19. Geyer M.A., Braff D.L. Habituation of the blink reflex in normals and schizophrenic patients. Psychophysiology 1982, 19:1-6.
20. Geyer M.A., Braff D.L. Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr. Bull. 1987, 13(4):643-668.
21. Geyer M.A., Swerdlow N.R., Mansbach R.S., Braff D.L. Startle response models of sensorimotor gating and habituation deficits in schizophrenia. Brain Res. Bull. 1990, 1990(25):485-498.
22. Giakoumaki S.G., Bitsios P., Frangou S. The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing. Brain Res. 2006, 1078(1):168-170.
23. Graham F.K. The more or less startling effects of weak prestimuli. Psychophysiology 1975, 12(238):248.
24. Granholm E., McQuaid J.R., Link P.C., Fish S., Patterson T., Jeste D.V. Neuropsychological predictors of functional outcome in Cognitive Behavioral Social Skills Training for older people with schizophrenia. Schizophr. Res. 2008, 100:133-143.
25. Hazlett E.A., Buchsbaum M.S. Sensorimotor gating deficits and hypofrontality in schizophrenia. Front. Biosci. 2001, 6:D1069-D1072.
26. Jennings P.D., Schell A.M., Filion D.L., Dawson M.E. Tracking early and late stages of information processing: contributions of startle eyeblink reflex modification. Psychophysiology 1996, 33:148-155.
27. Julian L.J., Mohr D.C. Cognitive predictors of response to treatment for depression in multiple sclerosis. J. Neuropsychiat. Clin. Neurosci. 2006, 18(3):356-363.
28. Karper L.P., Freeman G.K., Grillon C., Morgan C.A., Charney D.S., Krystal J.H. Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis. J. Neuropsychiatry Clin. Neurosci. 1996, 8(1):60-66.
29. Kasper S. Optimisation of long-term treatment in schizophrenia: treating the true spectrum of symptoms. Eur. Neuropsychopharmacol. 2006, 16(Suppl 3):S135-S141.
30. Kay S.R., Fiszbein P.S., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13:261-276.
31. Kumari V., Soni W., Sharma T. Influence of cigarette smoking on prepulse inhibition of the acoustic startle response in schizophrenia. Hum. Psychopharmacol. 2001, 16(4):321-326.
32. Kumari V., Antonova E., Geyer M.A., ffytche D., Williams S.C., Sharma T. A fMRI investigation of startle gating deficits in schizophrenia patients treated with typical or atypical antipsychotics. Int. J. Neuropsychopharmacol. 2007, 10(4):463-477.
33. Kumari V., Fannon D., Geyer M.A., Premkumar P., Antonova E., Simmons A., Kuipers E. Cortical grey matter volume and sensorimotor gating in schizophrenia. Cortex 2008, 44(9):1206-1214.
34. Kumari V., Peters E.R., Fannon D., Premkumar P., Aasen I., Cooke M.A., Anilkumar A.P., Kuipers E. Uncontrollable voices and their relationship to gating deficits in schizophrenia. Schizophr. Res. 2008, 101(1-3):185-194.
35. Kumari V., Peters E.R., Fannon D., Antonova E., Premkumar P., Anilkumar A.P., Williams S.C., Kuipers E. Dorsolateral prefrontal cortex activity predicts responsiveness to cognitive-behavioral therapy in schizophrenia. Biol. Psychiatry 2009, 66(6):594-602.
36. Kumari V., Antonova E., Fannon D., Peters E.R., Ffytche D.H., Premkumar P., Raveendran V., Andrew C., Johns L.C., McGuire P.A., Williams S.C., Kuipers E. Beyond dopamine: functional MRI predictors of responsiveness to cognitive behaviour therapy for psychosis. Front. Behav. Neurosci. 2010, 4(4):1-10.
37. Kumari V., Fannon D., Peters E.R., Ffytche D.H., Sumich A.L., Premkumar P., Anilkumar A.P., Andrew C., Phillips M.L., Williams S.C.R., Kuipers E. Neurobiology of cognitive behaviour therapy in psychosis: a longitudinal fMRI study. Brain 2011, 134(Pt 8):2396-2407.
38. Meincke U., Morth D., Voss T., Thelen B., Geyer M.A., Gouzoulis-Mayfrank E. Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis - a longitudinal study. Eur. Arch. Psychiatry Clin. Neurosci. 2004, 254(6):415-421.
39. Mohlman J., Gorman J.M. The role of executive functioning in CBT: a pilot study with anxious older adults. Behav. Res. Therapy 2005, 43(4):447-465.
40. Moorey S., Holting C., Hughes P., Knynenberg P., Michael A. Does problem solving ability predict therapy outcome in a clinical setting?. Behav. Cogn. Psychother. 2001, 29:485-495.
41. Nelson H., Willison J. National Adult Reading Test Manual 1991, Nfer-Nelson, Windsor.
42. NICE Schizophrenia: Core Interventions in the Treatment and Management of Schizophrenia in Primary and Secondary Care (update) 2009, Gaskell Press London, UK.
43. Penades R., Catalán R., Pujol N., Puig O., Guarch J., Masana G., Navarro V., Gastó C. Is memory impairment a rate limiter in cognitive behavioural therapy for chronic schizophrenia?. Psychother. Psychosom. 2010, 79(2):129-130.
44. Perivoliotis D., Grant P.M., Peters E.R., Ison R., Kuipers E., Beck A. Cognitive insight predicts favorable outcome in cognitive behavioural therapy for psychosis. Psychosis 2010, 2(1):23-33.
45. Perry W., Braff D. Information-processing deficits and thought disorder in Schizophrenia. Am. J. Psychiatry 1994, 151:363-367.
46. Perry W., Geyer M.A., Braff D.L. Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients. Arch. Gen. Psychiatry 1999, 56(3):277-281.
47. Peters E., Landau S., McCrone P., Cooke M., Fisher P., Steel C., Evans R., Carswell K., Dawson K., Williams S., Howard A., Kuipers E. A randomised controlled trial of cognitive behaviour therapy for psychosis in a routine clinical service. Acta Psychiatr. Scand. 2010, 122(4):302-318.
48. Pfammatter M., Junghan U.M., Brenner H.D. Efficacy of psychological therapy in schizophrenia: conclusions from meta-analyses. Schizophr. Bull. 2006, 32(Suppl 1):S64-S80.
49. Pilling S., Bebbington P., Kuipers E., Garety P., Geddes J., Geddes J., Orbach G., Morgan C. Psychological treatments in schizophrenia: I. Meta-analysis of family intervention and cognitive behaviour therapy. Psychol. Med. 2002, 32:763-782.
50. Potkin S.G., Weiden P.J., Loebel A.D., Warrington L.E., Watsky E.J., Siu C.O. Remission in schizophrenia: 196-week, double-blind treatment with ziprasidone vs. haloperidol. Int. J. Neuropsychopharmacol. 2009, 1-16.
51. Premkumar P., Fannon D., Kuipers E., Peters E.R., Anilkumar A.P., Simmons A., Kumari V. Structural magnetic resonance imaging predictors of responsiveness to cognitive behaviour therapy in psychosis. Schizophr. Res. 2009, 115(2-3):146-155.
52. Premkumar P., Parbhakar V.A., Fannon D., Lythgoe D., Williams S.C., Kuipers E., Kumari V. N-acetyl aspartate concentration in the anterior cingulate cortex in patients with schizophrenia: a study of clinical and neuropsychological correlates and preliminary exploration of cognitive behaviour therapy effects. Psychiatry Res. 2010, 182(3):251-260.
53. Premkumar P., Peters E.R., Fannon D., Anilkumar A.P., Kuipers E., Kumari V. Coping styles predict responsiveness to cognitive behaviour therapy in psychosis. Psychiatry Res. 2011, 187(3):354-362.
54. Sarin F., Wallin L., Widerlov B. Cognitive behaviour therapy for schizophrenia: a meta-analytical review of randomised controlled trials. Nord. J. Psychiatry 2011, 65(3):162-174.
55. Schell A.M., Wynn J.K., Dawson M.E., Sinaii N., Niebala C.B. Automatic and controlled attentional processes in startle eyeblink modification: effects of habituation of the prepulse. Psychophysiology 2000, 37:409-417.
56. Scholes K.E., Martin-Iverson M.T. Disturbed prepulse inhibition in patients with schizophrenia is consequential to dysfunction of selective attention. Psychophysiology 2010, 47(2):223-235.
57. Sensky T., Turkington D., Kingdon D., Scott J.L., Scott J., Siddle R., O'Carroll M., Barnes T.R. A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication. Arch. Gen. Psychiatry 2000, 57(2):165-172.
58. Siegle G.J., Carter C.S., Thase M.E. Use of FMRI to predict recovery from unipolar depression with cognitive behavior therapy. Am. J. Psychiatry 2006, 163(4):735-738.
59. Swerdlow N.R. Are we studying and treating schizophrenia correctly?. Schizophr. Res. 2011, 130(1-3):1-10.
60. Swerdlow N.R., Light G.A., Cadenhead K.S., Sprock J., Hsieh M.H., Braff D.L. Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch. Gen. Psychiatry 2006, 63(12):1325-1335.
61. Swerdlow N.R., Weber M., Qu Y., Light G.A., Braff D.L. Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology 2008, 199(3):331-388.
62. Takahashi H., Iwase M., Ishii R., Ohi K., Fukumoto M., Azechi M., Ikezawa K., Kurimoto R., Canuet L., Nakahachi T., Iike N., Tagami S., Morihara T., Okochi M., Tanaka T., Kazui H., Yoshida T., Tanimukai H., Yasuda Y., Kudo T., Hashimoto R., Takeda M. Impaired prepulse inhibition and habituation of acoustic startle response in Japanese patients with schizophrenia. Neurosci. Res. 2008, 62(3):187-194.
63. van der Gaag M. A neuropsychiatric model of biological and psychological processes in the remission of delusions and auditory hallucinations. Schizophr. Bull. 2006, 32(Suppl 1):S113-S122.
64. Wykes T., Steel C., Everitt B., Tarrier N. Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor. Schizophr. Bull. 2008, 34(3):523-537.
65. Zimmermann G., Favrod J., Trieu V.H., Pomini V. The effect of cognitive behavioral treatment on the positive symptoms of schizophrenia spectrum disorders: a meta-analysis. Schizophr. Res. 2005, 77:1-9.