Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 36, Issue 4, 2011, Pages 249-256

  Li, Tingting ^a   Li, Ning ^a   Guo, Qinglong ^a   Ji, Hui ^a   Zhao, Di ^a   Xie, Shan ^a   Li, Xiaonan ^a   Qiu, Zhixia ^a   Han, Deen ^a   Chen, Xijing ^a   You, Qidong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Cytochrome P450; Drug drug interaction; Enzyme inhibition; Wogonin

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; WOGONIN;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; METABOLIC CLEARANCE RATE;

ARYL HYDROCARBON HYDROXYLASES; BIOCATALYSIS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; ENZYME INHIBITORS; FLAVANONES; HUMANS; MICROSOMES, LIVER;

EID: 84856294149     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-011-0050-0     Document Type: Article

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