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Volumn 47, Issue 10, 2011, Pages 707-715

Endocrine differentiation of rat enterocytes in long-term three-dimensional co-culture with intestinal myofibroblasts

Author keywords

Enterocytes; Epithelial mesenchymal interaction; IEC 6 cells; Myofibroblasts; pdx 1

Indexed keywords

CDX2 PROTEIN, RAT; HOMEODOMAIN PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 84856287723     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-011-9458-8     Document Type: Article
Times cited : (9)

References (53)
  • 1
    • 0034905055 scopus 로고    scopus 로고
    • Characterization of conditions for the primary culture of human small intestinal epithelial cells
    • 10.1046/j.1365-2249.2001.01522.x
    • Aldhous M. C.; Shmakov A. N.; Bode J.; Ghosh S. Characterization of conditions for the primary culture of human small intestinal epithelial cells. Clin. Exp. Immunol. 125: 32-40; 2004.
    • (2004) Clin. Exp. Immunol , vol.125 , pp. 32-40
    • Aldhous, M.C.1    Shmakov, A.N.2    Bode, J.3    Ghosh, S.4
  • 2
    • 0020595095 scopus 로고
    • The role of pancreatico-biliary secretions in intestinal adaptation after resection, and its relationship to plasma enteroglucagon
    • Al-Mukhtar M. Y.; Sagor G. R.; Ghatei M. A.; Bloom S. R.; Wright N. A. The role of pancreatico-biliary secretions in intestinal adaptation after resection, and its relationship to plasma enteroglucagon. Br. J. Surg. 70: 398-400; 1983. (Pubitemid 13067867)
    • (1983) British Journal of Surgery , vol.70 , Issue.7 , pp. 398-400
    • Al Mukhtar, M.Y.T.1    Sagor, G.R.2    Ghatei, M.A.3
  • 5
    • 0023902580 scopus 로고
    • Differentiation of rat small intestinal epithelial cells by extracellular matrix
    • 3348402 1:STN:280:DyaL1c7mtFCiug%3D%3D
    • Carroll K. M.; Wong T. T.; Drabik D. L.; Chang E. B. Differentiation of rat small intestinal epithelial cells by extracellular matrix. Am. J. Physiol. 254: G355-G360; 1988.
    • (1988) Am. J. Physiol , vol.254
    • Carroll, K.M.1    Wong, T.T.2    Drabik, D.L.3    Chang, E.B.4
  • 6
    • 0030937750 scopus 로고    scopus 로고
    • Homeosis and intestinal tumours in Cdx2 mutant mice
    • DOI 10.1038/386084a0
    • Chawengsaksophak K.; James R.; Hammond V. E.; Kontgen F.; Beck F. Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 386: 84-87; 1997. (Pubitemid 27130925)
    • (1997) Nature , vol.386 , Issue.6620 , pp. 84-87
    • Chawiengsaksophak, K.1    James, R.2    Hammond, V.E.3    Kontgen, F.4    Beck, F.5
  • 8
    • 0030911194 scopus 로고    scopus 로고
    • Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells
    • Duluc I.; Lorentz O.; Fritsch C.; Leberquier C.; Kedinger M.; Freund J. N. Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells. J. Cell Sci. 110: 1317-1324; 1997. (Pubitemid 27273702)
    • (1997) Journal of Cell Science , vol.110 , Issue.11 , pp. 1317-1324
    • Duluc, I.1    Lorentz, O.2    Fritsch, C.3    Leberquier, C.4    Kedinger, M.5    Freund, J.-N.6
  • 9
    • 0026502307 scopus 로고
    • The development of a method for the preparation of rat intestinal epithelial cell primary cultures
    • 1569126
    • Evans G. S.; Flint N.; Somers A. S.; Eyden B.; Potten C. S. The development of a method for the preparation of rat intestinal epithelial cell primary cultures. J. Cell Sci. 101: 219-231; 1992.
    • (1992) J. Cell Sci , vol.101 , pp. 219-231
    • Evans, G.S.1    Flint, N.2    Somers, A.S.3    Eyden, B.4    Potten, C.S.5
  • 10
    • 0022385925 scopus 로고
    • Chromogranin: A newly recognized marker for endocrine cells of the human gastrointestinal tract
    • Facer P.; Bishop A. E.; Lloyd R. V.; Wilson B. S.; Hennessy R. J.; Polak J. M. Chromogranin: a newly recognized marker for endocrine cells of the human gastrointestinal tract. Gastroenterology 89: 1366-1373; 1985. (Pubitemid 16228062)
    • (1985) Gastroenterology , vol.89 , Issue.6 , pp. 1366-1373
    • Facer, P.1    Bishop, A.E.2    Lloyd, R.V.3
  • 11
    • 20544447734 scopus 로고    scopus 로고
    • Notch signals control the fate of immature progenitor cells in the intestine
    • DOI 10.1038/nature03589
    • Fre S.; Huyghe M.; Mourikis P.; Robine S.; Louvard D.; Artavanis-Tsakonas S. Notch signals control the fate of immature progenitor cells in the intestine. Nature 435: 964-968; 2005. (Pubitemid 40896323)
    • (2005) Nature , vol.435 , Issue.7044 , pp. 964-968
    • Fre, S.1    Huyghe, M.2    Mourikis, P.3    Robine, S.4    Louvard, D.5    Artavanis-Tsakonas, S.6
  • 12
    • 0033134041 scopus 로고    scopus 로고
    • Characterization of human intestinal stromal cell lines: Response to cytokines and interactions with epithelial cells
    • DOI 10.1006/excr.1999.4414
    • Fritsch C.; Orian-Rousseaul V.; Lefebvre O.; Simon-Assmann P.; Reimund J. M.; Duclos S.; Kedinger M. Characterization of human intestinal stromal cell lines: response to cytokines and interactions with epithelial cells. Exp. Cell Res. 248: 391-406; 1999. (Pubitemid 29394799)
    • (1999) Experimental Cell Research , vol.248 , Issue.2 , pp. 391-406
    • Fritsch, C.1    Orian-Rousseaul, V.2    Lefebvre, O.3    Simon-Assmann, P.4    Reimund, J.M.5    Duclos, B.6    Kedinger, M.7
  • 13
    • 0031042610 scopus 로고    scopus 로고
    • Cytokines modulate fibroblast phenotype and epithelial-stroma interactions in rat intestine
    • DOI 10.1053/gast.1997.v112.pm9041244
    • Fritsch C.; Simon-Assmann P.; Kedinger M.; Evans G. S. Cytokines modulate fibroblast phenotype and epithelial-stroma interactions in rat intestine. Gastroenterology 112: 826-838; 1997. (Pubitemid 27113808)
    • (1997) Gastroenterology , vol.112 , Issue.3 , pp. 826-838
    • Fritsch, C.1    Simon-Assmann, P.2    Kedinger, M.3    Evans, G.S.4
  • 14
    • 24344470560 scopus 로고    scopus 로고
    • Characteristics of subepithelial fibrolasts as a mechano-sensor in the intestine: Cell-shape-dependent ATP release and P2Y1 signaling
    • DOI 10.1242/jcs.02453
    • Furuya K.; Sokabe M.; Furuya S. Characteristics of subepithelial fibroblasts as a mechano-sensor in the intestine: cell-shape-dependent ATP release and P2Y1 signaling. J. Cell Sci. 118: 3289-3304; 2005. (Pubitemid 41246086)
    • (2005) Journal of Cell Science , vol.118 , Issue.15 , pp. 3289-3304
    • Furuya, K.1    Sokabe, M.2    Furuya, S.3
  • 15
    • 0027327215 scopus 로고
    • Characteristics of cultured subepithelial fibroblasts of rat duodenal villi
    • Furuya S.; Furuya K. Characteristics of cultured subepithelial fibroblasts of rat duodenal villi. Anat. Embryol. (Berl) 187: 529-538; 1993. (Pubitemid 23280407)
    • (1993) Anatomy and Embryology , vol.187 , Issue.6 , pp. 529-538
    • Furuya, S.1    Furuya, K.2
  • 16
    • 0019438740 scopus 로고
    • The myofibroblast: A key cell for wound healing and fibrocontractive diseases
    • 7015359 1:STN:280:DyaL3M7pvFKltQ%3D%3D
    • Gabbiani G. The myofibroblast: a key cell for wound healing and fibrocontractive diseases. Prog. Clin. Biol. Res. 54: 183-194; 1981.
    • (1981) Prog. Clin. Biol. Res , vol.54 , pp. 183-194
    • Gabbiani, G.1
  • 17
    • 0015225464 scopus 로고
    • Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
    • 5132594 10.1007/BF02147594 1:STN:280:DyaE38%2Fns1Krtw%3D%3D
    • Gabbiani G.; Ryan G. B.; Majne G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia 27: 549-550; 1971.
    • (1971) Experientia , vol.27 , pp. 549-550
    • Gabbiani, G.1    Ryan, G.B.2    Majne, G.3
  • 18
    • 0028006911 scopus 로고
    • Differentiation and self-renewal in the mouse gastrointestinal epithelium
    • DOI 10.1016/0955-0674(94)90047-7
    • Gordon J. I.; Hermiston M. L. Differentiation and self-renewal in the mouse gastrointestinal epithelium. Curr. Opin. Cell Biol. 6: 795-803; 1994. (Pubitemid 24357908)
    • (1994) Current Opinion in Cell Biology , vol.6 , Issue.6 , pp. 795-803
    • Gordon, J.I.1    Hermiston, M.L.L.2
  • 19
    • 0142020885 scopus 로고    scopus 로고
    • Regulation of adherens junctions and epithelial paracellular permeability: A novel function for polyamines
    • 12853285 1:CAS:528:DC%2BD3sXpt1Kjt7w%3D
    • Guo X.; Rao J. N.; Liu L.; Zou T. T.; Turner D. J.; Bass B. L.; Wang J. Y. Regulation of adherens junctions and epithelial paracellular permeability: a novel function for polyamines. Am. J. Physiol. Cell Physiol. 285: C1174-C1187; 2003.
    • (2003) Am. J. Physiol. Cell Physiol , vol.285
    • Guo, X.1    Rao, J.N.2    Liu, L.3    Zou, T.T.4    Turner, D.J.5    Bass, B.L.6    Wang, J.Y.7
  • 20
    • 0029806623 scopus 로고    scopus 로고
    • Fibroblasts and transforming growth factor β induce organization and differentiation of T84 human epithelial cells
    • DOI 10.1053/gast.1996.v111.pm8898639
    • Halttunen T.; Marttinen A.; Rantala I.; Kainulainen H.; Maki M. Fibroblasts and transforming growth factor beta induce organization and differentiation of T84 human epithelial cells. Gastroenterology 111: 1252-1262; 1996. (Pubitemid 26362250)
    • (1996) Gastroenterology , vol.111 , Issue.5 , pp. 1252-1262
    • Halttunen, T.1    Marttinen, A.2    Rantala, I.3    Kainulainen, H.4    Maki, M.5
  • 21
    • 0030901415 scopus 로고    scopus 로고
    • Enteroglucagon
    • DOI 10.1146/annurev.physiol.59.1.257
    • Holst J. J. Enteroglucagon. Annu. Rev. Physiol. 59: 257-271; 1997. (Pubitemid 27142442)
    • (1997) Annual Review of Physiology , vol.59 , pp. 257-271
    • Holst, J.J.1
  • 22
    • 0022457698 scopus 로고
    • Fetal gut mesenchyme induces differentiation of cultured intestinal endodermal and crypt cells
    • Kedinger M.; Simon-Assmann P. M.; Lacroix B.; Marxer A.; Hauri H. P.; Haffen K. Fetal gut mesenchyme induces differentiation of cultured intestinal endodermal and crypt cells. Dev. Biol. 113: 474-483; 1986. (Pubitemid 16074699)
    • (1986) Developmental Biology , vol.113 , Issue.2 , pp. 474-483
    • Kedinger, M.1    Simon-Assmann, P.M.2    Lacroix, B.3
  • 24
    • 0023115518 scopus 로고
    • Effects of growth factors on an intestinal epithelial cell line: Transforming growth factor β inhibits proliferation and stimulates differentiation
    • DOI 10.1016/0006-291X(87)91481-1
    • Kurokowa M.; Lynch K.; Podolsky D. K. Effects of growth factors on an intestinal epithelial cell line: transforming growth factor beta inhibits proliferation and stimulates differentiation. Biochem. Biophys. Res. Commun. 142: 775-782; 1987. (Pubitemid 17021100)
    • (1987) Biochemical and Biophysical Research Communications , vol.142 , Issue.3 , pp. 775-782
    • Kurokowa, M.1    Lynch, K.2    Podolsky, D.K.3
  • 25
    • 0029784341 scopus 로고    scopus 로고
    • Role of stromal myofibroblasts infiltrating colon cancer in tumor invasion
    • Martin M.; Pujuguet P.; Martin F. Role of stromal myofibroblasts infiltrating colon cancer in tumor invasion. Pathol. Res. Pract. 192: 712-717; 1996. (Pubitemid 26302245)
    • (1996) Pathology Research and Practice , vol.192 , Issue.7 , pp. 712-717
    • Martin, M.1    Pujuguet, P.2    Martin, F.3
  • 26
    • 0242692443 scopus 로고    scopus 로고
    • Creation of luminal tissue covered with urothelium by implantation of cultured urothelial cells into the peritoneal cavity
    • DOI 10.1097/01.ju.0000095785.89925.aa
    • Moriya K.; Kakizaki H.; Murakumo M.; Watanabe S.; Chen Q.; Nonomura K.; Koyanagi T. Creation of luminal tissue covered with urothelium by implantation of cultured urothelial cells into the peritoneal cavity. J. Urol. 170: 2480-2485; 2003. (Pubitemid 37414039)
    • (2003) Journal of Urology , vol.170 , Issue.6 , pp. 2480-2485
    • Moriya, K.1    Kakizaki, H.2    Murakumo, M.3    Watanabe, S.4    Chen, Q.5    Nonomura, K.6    Koyanagi, T.7
  • 28
    • 0030877562 scopus 로고    scopus 로고
    • Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: In vitro analysis of tumor- stromal interactions
    • Nakamura T.; Matsumoto K.; Kiritoshi A.; Tano Y. Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: in vitro analysis of tumor-stromal interactions. Cancer Res. 57: 3305-3313; 1997. (Pubitemid 27351751)
    • (1997) Cancer Research , vol.57 , Issue.15 , pp. 3305-3313
    • Nakamura, T.1    Matsumoto, K.2    Kiritoshi, A.3    Tano, Y.4    Nakamura, T.5
  • 31
    • 0031810769 scopus 로고    scopus 로고
    • Subepithelial fibroblast cell lines from different levels of gut axis display regional characteristics
    • 9612277 1:CAS:528:DyaK1cXjsFSitb4%3D
    • Plateroti M.; Rubin D. C.; Duluc I.; Singh R.; Foltzer-Jourdainne C.; Freund J. N.; Kedinger M. Subepithelial fibroblast cell lines from different levels of gut axis display regional characteristics. Am. J. Physiol. 274: G945-G954; 1998.
    • (1998) Am. J. Physiol , vol.274
    • Plateroti, M.1    Rubin, D.C.2    Duluc, I.3    Singh, R.4    Foltzer-Jourdainne, C.5    Freund, J.N.6    Kedinger, M.7
  • 34
    • 0028065367 scopus 로고
    • Abnormal basement membrane in tumors induced by rat colon cancer cells
    • Pujuguet P.; Hammann A.; Martin F.; Martin M. Abnormal basement membrane in tumors induced by rat colon cancer cells. Gastroenterology 107: 701-711; 1994. (Pubitemid 24265516)
    • (1994) Gastroenterology , vol.107 , Issue.3 , pp. 701-711
    • Pujuguet, P.1    Hammann, A.2    Martin, F.3    Martin, M.4
  • 35
    • 0030065033 scopus 로고    scopus 로고
    • Expression of fibronectin ED-A+ and ED-B+ isoforms by human and experimental colorectal cancer. Contribution of cancer cells and tumor-associated myofibroblasts
    • 8579120 1:CAS:528:DyaK28Xit1CnsLc%3D
    • Pujuguet P.; Hammann A.; Moutet M.; Samuel J. L.; Martin F.; Martin M. Expression of fibronectin ED-A+ and ED-B+ isoforms by human and experimental colorectal cancer. Contribution of cancer cells and tumor-associated myofibroblasts. Am. J. Pathol. 148: 579-592; 1996.
    • (1996) Am. J. Pathol , vol.148 , pp. 579-592
    • Pujuguet, P.1    Hammann, A.2    Moutet, M.3    Samuel, J.L.4    Martin, F.5    Martin, M.6
  • 36
    • 0018853640 scopus 로고
    • Establishment and characterization of intestinal epithelial cell cultures
    • 7412573 10.1016/S0091-679X(08)60695-0 1:STN:280:DyaL3M%2FhtFChtw%3D%3D
    • Quaroni A.; May R. J. Establishment and characterization of intestinal epithelial cell cultures. Methods Cell Biol. 21B: 403-427; 1980.
    • (1980) Methods Cell Biol , vol.21 , pp. 403-427
    • Quaroni, A.1    May, R.J.2
  • 38
    • 0031456449 scopus 로고    scopus 로고
    • Intestinal-type fibroblasts selectively influence proliferation rate and peptide synthesis in the murine entero-endocrine cell line STC-1
    • DOI 10.1046/j.1432-0436.1997.6230139.x
    • Ratineau C.; Plateroti M.; Dumortier J.; Blanc M.; Kedinger M.; Chayvialle J. A.; Roche C. Intestinal-type fibroblasts selectively influence proliferation rate and peptide synthesis in the murine entero-endocrine cell line STC-1. Differentiation 62: 139-147; 1997. (Pubitemid 28014715)
    • (1997) Differentiation , vol.62 , Issue.3 , pp. 139-147
    • Ratineau, C.1    Plateroti, M.2    Dumortier, J.3    Blanc, M.4    Kedinger, M.5    Chayvialle, J.A.6    Roche, C.7
  • 39
    • 60849094060 scopus 로고    scopus 로고
    • Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interactions with myofibroblasts
    • 19073897 10.1152/ajpcell.00383.2008 1:CAS:528:DC%2BD1MXitVaqsro%3D
    • Samuel S.; Walsh R.; Webb J.; Robins A.; Potten C.; Mahida Y. R. Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interactions with myofibroblasts. Am. J. Physiol. Cell Physiol. 296: C296-C305; 2009.
    • (2009) Am. J. Physiol. Cell Physiol , vol.296
    • Samuel, S.1    Walsh, R.2    Webb, J.3    Robins, A.4    Potten, C.5    Mahida, Y.R.6
  • 40
    • 46249128798 scopus 로고    scopus 로고
    • Bmi1 is expressed in vivo in intestinal stem cells
    • DOI 10.1038/ng.165, PII NG165
    • Sangiorgi E.; Capecchi M. R. Bmi1 is expressed in vivo in intestinal stem cells. Nat. Genet. 40: 915-920; 2008. (Pubitemid 351913652)
    • (2008) Nature Genetics , vol.40 , Issue.7 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 41
    • 0034789091 scopus 로고    scopus 로고
    • Glicentin, an active enteroglucagon, has a significant trophic role on the small intestine but not on the colon in the rat
    • DOI 10.1046/j.1365-2036.2001.01082.x
    • Sasaki M.; Fitzgerald A. J.; Mandir N.; Sasaki K.; Wright N. A.; Goodlad R. A. Glicentin, an active enteroglucagon, has a significant trophic role on the small intestine but not on the colon in the rat. Aliment. Pharmacol. Ther. 15: 1681-1686; 2001. (Pubitemid 32912413)
    • (2001) Alimentary Pharmacology and Therapeutics , vol.15 , Issue.10 , pp. 1681-1686
    • Sasaki, M.1    Fitzgerald, A.J.2    Mandir, N.3    Sasaki, K.4    Wright, N.A.5    Goodlad, R.A.6
  • 43
    • 0036089466 scopus 로고    scopus 로고
    • Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: Effect of eradication of Helicobacter pylori
    • DOI 10.1046/j.1523-5378.2002.00080.x
    • Satoh K.; Mutoh H.; Eda A.; Yanaka I.; Osawa H.; Honda S.; Kawata H.; Kihira K.; Sugano K. Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. Helicobacter 7: 192-198; 2002. (Pubitemid 34665837)
    • (2002) Helicobacter , vol.7 , Issue.3 , pp. 192-198
    • Satoh, K.1    Mutoh, H.2    Eda, A.3    Yanaka, I.4    Osawa, H.5    Honda, S.6    Kawata, H.7    Kihira, K.8    Sugano, K.9
  • 44
    • 2542446343 scopus 로고    scopus 로고
    • Minireview: Development and differentiation of gut endocrine cells
    • DOI 10.1210/en.2004-0051
    • Schonhoff S. E.; Giel-Moloney M.; Leiter A. B. Minireview: development and differentiation of gut endocrine cells. Endocrinology 145: 2639-2644; 2004. (Pubitemid 38686209)
    • (2004) Endocrinology , vol.145 , Issue.6 , pp. 2639-2644
    • Schonhoff, S.E.1    Giel-Moloney, M.2    Leiter, A.B.3
  • 45
    • 34249987090 scopus 로고    scopus 로고
    • Intestine-Specific Ablation of Mouse atonal homolog 1 (Math1) Reveals a Role in Cellular Homeostasis
    • DOI 10.1053/j.gastro.2007.03.047, PII S0016508507005719
    • Shroyer N. F.; Helmrath M. A.; Wang V. Y.; Antalffy B.; Henning S. J.; Zoghbi H. Y. Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis. Gastroenterology 132: 2478-2488; 2007. (Pubitemid 46890862)
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2478-2488
    • Shroyer, N.F.1    Helmrath, M.A.2    Wang, V.Y.-C.3    Antalffy, B.4    Henning, S.J.5    Zoghbi, H.Y.6
  • 47
    • 0030032310 scopus 로고    scopus 로고
    • An intestine-specific homeobox gene regulates proliferation and differentiation
    • Suh E.; Traber P. G. An intestine-specific homeobox gene regulates proliferation and differentiation. Mol. Cell. Biol. 16: 619-625; 1996. (Pubitemid 26029101)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.2 , pp. 619-625
    • Suh, E.1    Traber, P.G.2
  • 48
    • 0041622897 scopus 로고    scopus 로고
    • Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells
    • DOI 10.1016/S0090-8258(03)00335-4
    • Tanaka R.; Saito T.; Ashihara K.; Nishimura M.; Mizumoto H.; Kudo R. Three-dimensional co-culture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells. Gynecol. Oncol. 90: 297-304; 2003. (Pubitemid 36952017)
    • (2003) Gynecologic Oncology , vol.90 , Issue.2 , pp. 297-304
    • Tanaka, R.1    Saito, T.2    Ashihara, K.3    Nishimura, M.4    Mizumoto, H.5    Kudo, R.6
  • 49
    • 67651159312 scopus 로고    scopus 로고
    • Stem cells, self-renewal, and differentiation in the intestinal epithelium
    • 10.1146/annurev.physiol.010908.163145
    • van der Flier L. G.; Clevers H. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu. Rev. Physiol. 71: 241-260; 2008.
    • (2008) Annu. Rev. Physiol , vol.71 , pp. 241-260
    • Van Der Flier, L.G.1    Clevers, H.2
  • 50
    • 40049083413 scopus 로고    scopus 로고
    • Deciphering the 'black box' of the intestinal stem cell niche: Taking direction from other systems
    • DOI 10.1097/MOG.0b013e3282f4954f, PII 0000157420080300000004
    • Walker M. R.; Stappenbeck T. S. Deciphering the black box of the intestinal stem cell niche: taking direction from other systems. Curr. Opin. Gastroenterol. 24: 115-120; 2008. (Pubitemid 351322775)
    • (2008) Current Opinion in Gastroenterology , vol.24 , Issue.2 , pp. 115-120
    • Walker, M.R.1    Stappenbeck, T.S.2
  • 52
    • 0037462878 scopus 로고    scopus 로고
    • Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression
    • DOI 10.1016/S0006-291X(02)02935-2
    • Yamamoto H.; Bai Y. Q.; Yuasa Y. Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression. Biochem. Biophys. Res. Commun. 300: 813-818; 2003. (Pubitemid 36259834)
    • (2003) Biochemical and Biophysical Research Communications , vol.300 , Issue.4 , pp. 813-818
    • Yamamoto, H.1    Bai, Y.-Q.2    Yuasa, Y.3


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