Comparative modeling of UDP-N-acetylmuramoyl-glycyl-D-glutamate-2, 6-diaminopimelate ligase from Mycobacterium leprae and analysis of its binding features through molecular docking studies

Journal of Molecular Modeling

Volumn 18, Issue 1, 2012, Pages 115-125

  Shanmugam, Anusuya ^a   Natarajan, Jeyakumar ^b  

^a Vinayaka Missions University   (India)

^b BHARATHIAR UNIVERSITY   (India)

Author keywords

Comparative modeling; Docking; Leprosy; M. leprae; Peptidoglycan

Indexed keywords

LIGASE; UDP N ACETYLMURAMOYLGLYCYL DEXTRO GLUTAMATE 2,6 DIAMINOPIMELATE LIGASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR DOCKING; MOLECULAR MODEL; MYCOBACTERIUM LEPRAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ESCHERICHIA COLI; MODELS, CHEMICAL; MODELS, MOLECULAR; MYCOBACTERIUM LEPRAE; PEPTIDE SYNTHASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN;

MYCOBACTERIUM; MYCOBACTERIUM LEPRAE;

EID: 84856287465     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-011-1039-y     Document Type: Article

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