Wnt signaling: The β-cat(enin)'s meow

Genes and Development

Volumn 26, Issue 2, 2012, Pages 105-109

  Bauer, Matthieu ^a   Willert, Karl ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Canonical wnt signaling; Cell fate determination in the dorsal neural tube; Mouse strains expressing transcriptionally inactive catenin; Signaling versus structural function of catenin

Indexed keywords

CONNECTIN; CYTOPLASM PROTEIN; HEAT SHOCK PROTEIN 90; HISTONE LYSINE METHYLTRANSFERASE; MUSCLE PROTEIN; PROTEIN SMYD2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MUSCLE FUNCTION; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN METHYLATION; PROTEIN STABILITY; SKELETAL MUSCLE;

ANIMALS; BETA CATENIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL;

EID: 84856284501     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.185280.111     Document Type: Article

References (21)

1. Barker N, Hurlstone A, Musisi H, Miles A, Bienz M, Clevers H. 2001. The chromatin remodelling factor Brg-1 interacts with b-catenin to promote target gene activation. EMBO J 20: 4935-4943
2. Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. 1998. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol 8: 1323-1326
3. Dickinson DJ, Nelson WJ, Weis WI. 2011. A polarized epithelium organized by β-and α-catenin predates cadherin and metazoan origins. Science 331: 1336-1339
4. Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, Kemler R. 1995. Lack of β-catenin affects mouse development at gastrulation. Development 121: 3529-3537
5. Hecht A, Litterst CM, Huber O, Kemler R. 1999. Functional characterization of multiple transactivating elements in b-catenin, some of which interact with the TATA-binding protein in vitro. J Biol Chem 274: 18017-18025
6. Huber AH, Nelson WJ, Weis WI. 1997. Three-dimensional structure of the armadillo repeat region of b-catenin. Cell 90: 871-882
7. Huelsken J, Vogel R, Brinkmann V, Erdmann B, Birchmeier C, Birchmeier W. 2000. Requirement for b-catenin in anterior-posterior axis formation in mice. J Cell Biol 148: 567-578
8. Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. 2001. β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105: 533-545
9. Kramps T, Peter O, Brunner E, Nellen D, Froesch B, Chatterjee S, Murone M, Zullig S, Basler K. 2002. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear b-catenin-TCF complex. Cell 109: 47-60
10. Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, Karsten U, van de Wetering M, Clevers H, Schlag PM, Birchmeier W, et al. 2002. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol 22: 1184-1193
11. Maretto S, Cordenonsi M, Dupont S, Braghetta P, Broccoli V, Hassan AB, Volpin D, Bressan GM, Piccolo S. 2003. Mapping Wnt/b-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci 100: 3299-3304
12. McCrea PD, Brieher WM, Gumbiner BM. 1993. Induction of a secondary body axis in Xenopus by antibodies to β-catenin. J Cell Biol 123: 477-484
13. Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, Roose J, Destree O, Clevers H. 1996. XTcf-3 transcription factor mediates b-catenininduced axis formation in Xenopus embryos. Cell 86: 391-399
14. Orsulic S, Peifer M. 1996. An in vivo structure-function study of armadillo, the β-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling. J Cell Biol 134: 1283-1300
15. Parker DS, Jemison J, Cadigan KM. 2002. Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila. Development 129: 2565-2576
16. Takemaru KI, Moon RT. 2000. The transcriptional coactivator CBP interacts with b-catenin to activate gene expression. J Cell Biol 149: 249-254
17. Thompson B, Townsley F, Rosin-Arbesfeld R, Musisi H, Bienz M. 2002. A new nuclear component of the Wnt signalling pathway. Nat Cell Biol 4: 367-373
18. Valenta T, Gay M, Steiner S, Draganova K, Zemke M, Hoffmans R, Cinelli P, Aguet M, Sommer L, Basler K. 2011. Probing transcription-specific outputs of β-catenin in vivo. Genes Dev 25: 2631-2643
19. Vleminckx K, Kemler R, Hecht A. 1999. The C-terminal transactivation domain of β-catenin is necessary and sufficient for signaling by the LEF-1/ β-catenin complex in Xenopus laevis. Mech Dev 81: 65-74
20. Widmann TJ, Dahmann C. 2009. Wingless signaling and the control of cell shape in Drosophila wing imaginal discs. Dev Biol 334: 161-173
21. Wodarz A, Stewart DB, Nelson WJ, Nusse R. 2006. Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells. J Cell Sci 119: 2425-2434.