HPLC-MS/MS method for the pharmacokinetic study of itraconazole a low UV absorbable drug involving Wistar rats

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 20, 2011, Pages 2565-2582

  Dharuman, J ^a   Vsudhevan, M ^b   Ajithlal, T ^b   Somasekaran, K N ^c  

^a KMCH COLLEGE OF PHARMACY   (India)

^b Roxaane Research Laboratories Pvt Ltd   (India)

^c SASTRA UNIVERSITY   (India)

Author keywords

itraconazole LCMASS; itraconazole LCMS; itraconazole LCMSMS; itraconazole mass; itraconazoletandem MSMS

Indexed keywords

AGILENT; AMMONIUM FORMATE; CHARACTERISTIC PEAKS; CHROMATOGRAPHIC SEPARATIONS; CONCENTRATION RANGES; DIETHYL ETHERS; HPLC-MS/MS; INTERNAL STANDARDS; ITRACONAZOLE; ITRACONAZOLE MASS; ITRACONAZOLETANDEM MSMS; LC-MS/MS; MOBILE PHASE; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; RAT PLASMA; SELECTIVE REACTION MONITORING; STATIONARY PHASE; TANDEM MASS SPECTROMETRY; VERAPAMIL; WISTAR RAT;

AMMONIUM COMPOUNDS; ELECTROSPRAY IONIZATION; ETHERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; RATS; SEPARATION;

PHARMACOKINETICS;

DICHLOROMETHANE; ETHER; ITRACONAZOLE; VERAPAMIL;

ACIDITY; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG DETERMINATION; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; RAT; TANDEM MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

EID: 84856276024     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.593068     Document Type: Article

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