cAMP-dependent allostery and dynamics in Epac: An NMR view

Biochemical Society Transactions

Volumn 40, Issue 1, 2012, Pages 219-223

  Selvaratnam, Rajeevan ^a   Akimoto, Madoka ^a   VanSchouwen, Bryan ^a   Melacini, Giuseppe ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Allostery; cAMP; cGMP; Chemical shift covariance analysis (CHESCA); Exchange protein directly activated by cAMP (Epac); Nuclear magnetic resonance (NMR); Protein dynamics

Indexed keywords

CYCLIC AMP; CYCLIC AMP RECEPTOR; CYCLIC GMP; PROTEIN EPAC; UNCLASSIFIED DRUG;

ALLOSTERISM; BINDING SITE; CHEMICAL SHIFT COVARIANCE ANALYSIS; DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; REVIEW; STATISTICAL ANALYSIS;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; AMINO ACID MOTIFS; ANIMALS; CYCLIC AMP; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING;

EID: 84856272126     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20110628     Document Type: Review

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