Comparison of fecal elastase-1 and pancreatic function testing in children

Journal of Pediatric Gastroenterology and Nutrition

Volumn 54, Issue 2, 2012, Pages 277-280

  Wali, Prateek D ^a   Loveridge Lenza, Beth ^a   He, Zhaoping ^a   Horvath, Karoly ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

fecal elastase 1; pancreatic elastase

Indexed keywords

PANCREATIC ELASTASE; SECRETIN;

ADOLESCENT; AGE; ARTICLE; CHILD; CONCENTRATION (PARAMETERS); CORRELATION ANALYSIS; CYSTIC FIBROSIS; ENZYME ACTIVITY; ENZYME DEFICIENCY; FALSE POSITIVE RESULT; FECES ANALYSIS; FEMALE; HUMAN; INFANT; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NON INVASIVE PROCEDURE; PANCREAS FUNCTION TEST; PANCREAS INSUFFICIENCY; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; STIMULATION; SUPPLEMENTATION; WEIGHT GAIN;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; EXOCRINE PANCREATIC INSUFFICIENCY; FECES; HUMANS; INFANT; PANCREAS; PANCREATIC ELASTASE; PANCREATIC FUNCTION TESTS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SECRETIN; SENSITIVITY AND SPECIFICITY;

EID: 84856248552     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31820b0227     Document Type: Article

References (29)

1. Walkowiak J, Nousia-Arvanitakis S, Henker J, et al. Indirect pancreatic function tests in children. J Pediatr Gastroenterol Nutr 2005;40:107-14. (Pubitemid 40269722)
2. Walkowiak J, Cichy WK, Herzig KH. Comparison of fecal elastase-1 determination with the secretin-cholecystokinin test in patients with cystic fibrosis. Scand J Gastroenterol 1999;34:202-7. (Pubitemid 29138874)
3. Sziegoleit A, Krause E, Klor HU, et al. Elastase 1 and chymotrypsin B in pancreatic juice and feces. Clin Biochem 1989;22:85-9. (Pubitemid 19121436)
4. Loser C, Mollgaard A, Folsch UR. Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test. Gut 1996; 39:580-6. (Pubitemid 26376043)
5. Glasbrenner B, Schon A, Klatt S, et al. Clinical evaluation of the faecal elastase test in the diagnosis and staging of chronic pancreatitis. Eur J Gastroenterol Hepatol 1996;8:1117-20. (Pubitemid 26383872)
6. Gullo L, Ventrucci M, Tomassetti P, et al. Fecal elastase 1 determination in chronic pancreatitis. Dig Dis Sci 1999;44:210-3. (Pubitemid 29053101)
7. Carroccio A, Verghi F, Santini B, et al. Diagnostic accuracy of fecal elastase 1 assay in patients with pancreatic maldigestion or intestinal malabsorption: a collaborative study of the Italian Society of Pediatric Gastroenterology and Hepatology. Dig Dis Sci 2001;46:1335-42. (Pubitemid 32523283)
8. Dominguez-Munoz JE, Hieronymus C, Sauerbruch T, et al. Fecal elastase test: evaluation of a new noninvasive pancreatic function test. Am J Gastroenterol 1995;90:1834-7.
9. Katschinski M, Schirra J, Bross A, et al. Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis. Pancreas 1997;15:191-200. (Pubitemid 27524696)
10. Luth S, Teyssen S, Forssmann K, et al. Fecal elastase-1 determination: "gold standard" of indirect pancreatic function tests? Scand J Gastroenterol 2001;36:1092-9. (Pubitemid 32801697)
11. Walkowiak J, Herzig KH, Strzykala K, et al. Fecal elastase-1 is superior to fecal chymotrypsin in the assessment of pancreatic involvement in cystic fibrosis. Pediatrics 2002;110(1 Pt 1):e7.
12. Sziegoleit A, Linder D. Studies on the sterol-binding capacity of human pancreatic elastase 1. Gastroenterology 1991;100:768-74.
13. Beharry S, Ellis L, Corey M, et al. How useful is fecal pancreatic elastase 1 as a marker of exocrine pancreatic disease? J Pediatr 2002;141:84-90. (Pubitemid 34774956)
14. Nousia-Arvanitakis S. Fecal elastase-1 concentration: an indirect test of exocrine pancreatic function and a marker of an enteropathy regardless of cause. J Pediatr Gastroenterol Nutr 2003;36:314-5. (Pubitemid 39274602)
15. Walkowiak J, Lisowska A. Re: fecal elastase: pancreatic status verification and influence on nutritional status in children with cystic fibrosis. J Pediatr Gastroenterol Nutr 2006;42:117-8.
16. Walkowiak J, Nousia-Arvanitakis S, Agguridaki C, et al. Longitudinal follow-up of exocrine pancreatic function in pancreatic sufficient cystic fibrosis patients using the fecal elastase-1 test. J Pediatr Gastroenterol Nutr 2003;36:474-8. (Pubitemid 39280886)
17. Walkowiak J, Lisowska A, Przyslawski J, et al. Faecal elastase-1 test is superior to faecal lipase test in the assessment of exocrine pancreatic function in cystic fibrosis. Acta Paediatr 2004;93:1042-5. (Pubitemid 39452783)
18. Nousia-Arvanitakis S, Karagiozoglou-Lamboudes T, Aggouridaki C, et al. Influence of jejunal morphology changes on exocrine pancreatic function in celiac disease. J Pediatr Gastroenterol Nutr 1999;29:81-5. (Pubitemid 30345833)
19. Walkowiak J, Herzig KH. Fecal elastase-1 is decreased in villous atrophy regardless of the underlying disease. Eur J Clin Invest 2001; 31:425-30. (Pubitemid 32476962)
20. Salvatore S, Finazzi S, Barassi A, et al. Low fecal elastase: potentially related to transient small bowel damage resulting from enteric pathogens. J Pediatr Gastroenterol Nutr 2003;36:392-6. (Pubitemid 39274615)
21. Ghishan FK, Lee PC, Lebenthal E, et al. Isolated congenital enterokinase deficiency. Recent findings and review of the literature. Gastroenterology 1983;85:727-31. (Pubitemid 13033136)
22. Ghishan FK, Moran JR, Durie PR, et al. Isolated congenital lipasecolipase deficiency. Gastroenterology 1984;86:1580-2.
23. Hildebrand H, Borgstrom B, Bekassy A, et al. Isolated co-lipase deficiency in two brothers. Gut 1982;23:243-6. (Pubitemid 12183738)
24. Ligumsky M, Granot E, Branski D, et al. Isolated lipase and colipase deficiency in two brothers. Gut 1990;31:1416-8.
25. Lilibridge CB, Townes PL. Physiologic deficiency of pancreatic amylase in infancy: a factor in iatrogenic diarrhea. J Pediatr 1973;82:279-82.
26. Mehta DI, Wang HH, Akins RE, et al. Isolated pancreatic amylase deficiency: probable error in maturation. J Pediatr 2000;136:844-6. (Pubitemid 30415666)
27. Meyts I, Wuyts W, Proesmans M, et al. Variability of fecal pancreatic elastase measurements in cystic fibrosis patients. J Cyst Fibros 2002; 1:265-8.
28. Del Rosario MA, Fitzgerald JF, Gupta SK, et al. Direct measurement of pancreatic enzymes after stimulation with secretin versus secretin plus cholecystokinin. J Pediatr Gastroenterol Nutr 2000;31:28-32. (Pubitemid 30456571)
29. Madrazo-de la Garza JA, Gotthold M, Lu RB, et al. A new direct pancreatic function test in pediatrics. J Pediatr Gastroenterol Nutr 1991;12:356-60.