Clinical evaluation of the faecal elastase test in the diagnosis and staging of chronic pancreatitis

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 11, 1996, Pages 1117-1120

  Glasbrenner, Bernhard ^a   Schön, Annett ^a   Klatt, Stefan ^a   Beckh, Karlheinz ^a   Adler, Guido ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Chronic pancreatitis; Exocrine pancreatic function; Faecal chymotrypsin; Faecal elastase test; Pancreolauryl serum test

Indexed keywords

CHYMOTRYPSIN; ELASTASE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC PANCREATITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PANCREAS FUNCTION; PANCREAS FUNCTION TEST; PANCREOLAURYL TEST; PRIORITY JOURNAL; SMALL INTESTINE DISEASE; STAGING;

EID: 0029805783     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199611000-00016     Document Type: Article

References (26)

1. Gullo L: Value and clinical role of intubation tests in chronic pancreatitis. In Chronic Pancreatitis. Edited by Beger HG, Büchler M, Ditschuneit H, Malfertheiner P. Berlin, Heidelberg: Springer Verlag; 1990:287-290.
2. Forsmark CE, Toskes PP: What does an abnormal pancreatogram mean? Gastrointest Endosc Clin North Am 1995, 5:105-123.
3. Malfertheiner P, Glasbrenner B: Exokrine Pankreasfunktions tests. In Erkrankungen des Exkretorischen Pankreas. Edited by Mössner J, Adler G, Fölsch UR, Singer MV. Jena, Stuttgart: Gustav Fischer Verlag; 1995:147-156.
4. Lankisch PG: Value of indirect pancreatic function tests. In Chronic Pancreatitis. Edited by Beger HG, Büchler M, Ditschuneit H, Malfertheiner P. Berlin, Heidelberg: Springer Verlag; 1990:291-301.
5. Lankisch PG: Function tests in the diagnosis of chronic pancreatitis. Int J Pancreatol 1993, 14:9-20.
6. Lankisch PG: The indirect pancreatic function test 'Pancreolauryl' in chronic pancreatitis. In Diagnostic Procedures in Pancreatic Disease. Edited by Malfertheiner P, Ditschuneit H. Berlin, Heidelberg: Springer Verlag; 1986:223-230.
7. Malfertheiner P, Büchler M, Müller A, Ditschuneit H: Fluorescein dilaurate (FDL) serum test - a rapid tubeless pancreatic function test. Pancreas 1987, 2:53-60.
8. Adler C, Weidenbach H: Fecal chymotrypsin in chronic pancreatic disease. In Diagnostic Procedures in Pancreatic Disease. Edited by Malfertheiner P, Ditschuneit H. Berlin, Heidelberg: Springer Verlag; 1986:231-237.
9. Ammann R, Tagwercher E, Kashiwagi H, Rosenmund H: Diagnostic value of fecal chymotrypsin and trypsin assessment for detection of pancreatic disease. Am J Dig Dis 1968, 13:123-146.
10. Dürr GHK, Otte M, Forell MM; Bode JC: Fecal chymotrypsin: a study on its diagnostic value by comparison with the secretin-cholecystokinin test. Digestion 1978, 17:404-409.
11. DiMagno EP: Ultrasound, computed tomography and endoscopic retrograde pancreatography in the diagnosis of chronic pancreatitis: a comparative evaluation. In Diagnostic Procedures in Pancreatic Disease. Edited by Malfertheiner P, Ditschuneit H. Berlin, Heidelberg: Springer Verlag; 1986:185-191.
12. Rösch T, Classen M: Role of ERCP in chronic pancreatitis. In Chronic Pancreatitis. Edited by Beger HG, Büchler M, Ditschuneit H, Malfertheiner P. Berlin, Heidelberg: Springer Verlag; 1990:319-329.
13. Szigoleit A, Linder D: Die menschliche Pankreaselastase 1. Biochemische und klinische Aspekte. Med Welt 1991, 42:682-684.
14. Scheefers-Borchel U, Scheefers H, Arnold R, Fischer P, Szigoleit A: Pankreatische Elastase 1: Parameter für die chronische und akute Pankreatitis. Lab Med 1992, 16:427-432.
15. Katschinski M, Schirra J, Broß A, Arnold R, Göke B: Patterns of duodenal secretion and fecal excretion of pancreatic elastase 1 in healthy humans and patients with exocrine pancreatic insufficiency [abstract]. Digestion 1994, 55:307.
16. Dominguez-Munoz JE, Hieronymus C, Sauerbruch T, Malfertheiner P: Fecal elastase test: evaluation of a new non-invasive pancreatic function lest. Am J Gastroenterol 1995, 90:1834-1837.
17. Stein J, Jung M, Sziegoleit A, Zeuzem S, Caspary WF, Lembcke B: Immunoreactive elastase I: clinical evaluation of a new noninvasive test of pancreatic function. Clin Chem 1996, 42:222-226.
18. Löser C, Mölgaard A, Fölsch UR: Fecal elastase 1: an easy, inexpensive and highly sensitive and specific tubeless routine test in pancreatic insufficiency [abstract]. Gut 1995, 37(suppl. 2):A140.
19. Glasbrenner B, Beckh KH, Adler G: Comparison of fecal elastase 1 with other indirect pancreatic function tests [abstract]. Digestion 1994, 55:301.
20. Axon ATR, Classen M, Cotton PB, Cremer M, Freeny PC, Lees WR: Pancreatography in chronic pancreatitis: international definitions. Gut 1984; 25:1107-1112.
21. Kaspar P, Moeller G, Wahlefeld AW, Staehler F: A new photometric method for the determination of chymotrypsin in stool. Z Anal Chem 1982, 311:391-392.
22. Brown CA, Sule SE, Williams J, Puntis JWL, Booth IW, McNeish AS: Feacal chymotrypsin: a reliable index of exocrine pancreatic function. Arch Dis Child 1988, 63:785-789.
23. Lankisch PG, Brauneis J, Otto J, Coke B: Pancreolauryl and PABA tests. Are serum tests more practicable alternatives to urine tests in the diagnosis of exocrine pancreatic insufficiency. Gastroenterology 1986, 90:350-354.
24. Buscail L, Escourrou J, Moreau J, Delvaux M, Louvel D, Lapeyre F, et al.: Endoscopic ultrasonography in chronic pancreatitis: a comparative study with conventional ultrasonography, computed tomography, and ERCP. Pancreas 1995, 10:251-257.
25. Schneider R, Dürr HK, Bode J: Diagnostische Wertigkeit der Bestimmung von Chymotrypsin im Stuhl für die Erfassung einer exokrinen Pankreasinsuffizienz. Dtsch Med Wochenschr 1974, 99:1449-1454.
26. Lankisch PG, Löhr M, König H, Schmidt I, Knollmann R, Liebe S: Fecal elastase-1: not helpful in diagnosing chronic pancreatitis with slight to moderate exocrine pancreatic in sufficiency. Gastroenterology 1996, 110:A408.