-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010;60:277-300
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
3
-
-
0033978220
-
Systemic therapy for renal cell carcinoma
-
Motzer RJ, Russo P. Systemic therapy for renal cell carcinoma. J Urol 2000;163:408-17 (Pubitemid 30060482)
-
(2000)
Journal of Urology
, vol.163
, Issue.2
, pp. 408-417
-
-
Motzer, R.J.1
Russo, P.2
-
5
-
-
17944397580
-
Five-year survival results of subcutaneous low-dose immunotherapy with interleukin-2 alone in metastatic renal cell cancer patients
-
Bordin V, Giani L, Meregalli S, et al. Five-year survival results of subcutaneous low-dose immunotherapy with interleukin-2 alone in metastatic renal cell cancer patients. Urol Int 2000;64:3-8 (Pubitemid 30224033)
-
(2000)
Urologia Internationalis
, vol.64
, Issue.1
, pp. 3-8
-
-
Bordin, V.1
Giani, L.2
Meregalli, S.3
Bukovec, R.4
Vaghi, M.M.5
Mandala, M.6
Paolorossi, F.7
Ardizzoia, A.8
Tancini, G.9
Barni, S.10
Frigerio, F.11
Fumagalli, L.12
Bordoni, A.13
Valsuani, G.14
Di Felice, G.15
Lissoni, P.16
-
6
-
-
24044489895
-
Metastatic renal carcinoma long-term survivors treated with s.c. interferon-alpha and s.c. interleukin-2
-
DOI 10.1089/cbr.2005.20.410
-
Atzpodien J, Reitz M. Metastatic renal carcinoma long-term survivors treated with s.c. interferon-alpha and s.c. interleukin-2. Cancer Biother Radiopharm 2005;20:410-16 (Pubitemid 41216105)
-
(2005)
Cancer Biotherapy and Radiopharmaceuticals
, vol.20
, Issue.4
, pp. 410-416
-
-
Atzpodien, J.1
Reitz, M.2
-
7
-
-
0032772880
-
Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
-
Motzer RJ, Mazumdar M, Bacik J, et al. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol 1999;17:2530-40 (Pubitemid 29368255)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.8
, pp. 2530-2540
-
-
Motzer, R.J.1
Mazumdar, M.2
Bacik, J.3
Berg, W.4
Amsterdam, A.5
Ferrara, J.6
-
8
-
-
0036138580
-
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
-
DOI 10.1200/JCO.20.1.289
-
Motzer RJ, Bacik J, Murphy BA, et al. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 2002;20:289-96 (Pubitemid 34032623)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.1
, pp. 289-296
-
-
Motzer, R.J.1
Bacik, J.2
Murphy, B.A.3
Russo, P.4
Mazumdar, M.5
-
9
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
Bjornsti MA, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev 2004;4:335-48 (Pubitemid 38579480)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 335-348
-
-
Bjornsti, M.-A.1
Houghton, P.J.2
-
10
-
-
34547192850
-
The mammalian target of rapamycin kinase and tumor growth inhibition
-
Boulay A, Lane HA. The mammalian target of rapamycin kinase and tumor growth inhibition. Recent Results Cancer Res 2007;172:99-124
-
(2007)
Recent Results Cancer Res
, vol.172
, pp. 99-124
-
-
Boulay, A.1
Lane, H.A.2
-
11
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G, Carducci M, Tomczak P, et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007;356:2271-81 (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
12
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 2008;372:449-56
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
13
-
-
34447120142
-
Sorafenib and sunitinib in renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-06-2844
-
Stein MN, Flaherty KT. CCR drug updates: sorafenib and sunitinib in renal cell carcinoma. Clin Cancer Res 2007;13:3765-70 (Pubitemid 47037579)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.13
, pp. 3765-3770
-
-
Stein, M.N.1
Flaherty, K.T.2
-
14
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007;356:115-24 (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
15
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 2009;27:3584-90
-
(2009)
J Clin Oncol
, vol.27
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
16
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010;28:1061-8
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
17
-
-
80052225008
-
Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): Results of phase III AXIS trial
-
Rini BI. Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): results of phase III AXIS trial. J Clin Oncol 2011;29:15S
-
(2011)
J Clin Oncol
, vol.29
-
-
Rini, B.I.1
-
18
-
-
77952300540
-
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
-
Escudier B, Bellmunt J, Negrier S, et al. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol 2010;28:2144-50
-
(2010)
J Clin Oncol
, vol.28
, pp. 2144-2150
-
-
Escudier, B.1
Bellmunt, J.2
Negrier, S.3
-
19
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, et al. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol 2010;28:2137-43
-
(2010)
J Clin Oncol
, vol.28
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
-
20
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-1443
-
Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109 (Pubitemid 39331023)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
21
-
-
33646272299
-
Pharmacodynamic study of BAY 43-9006 in patients with metastatic renal cell carcinoma [abstract 3005]. ASCO annual meeting proceedings, 41st annual meeting
-
O'Dwyer PJ, Rosen M, Gallagher M, et al. Pharmacodynamic study of BAY 43-9006 in patients with metastatic renal cell carcinoma [abstract 3005]. ASCO Annual Meeting Proceedings, 41st Annual Meeting. J Clin Oncol 2005;23:193S
-
(2005)
J Clin Oncol
, vol.23
-
-
O'dwyer, P.J.1
Rosen, M.2
Gallagher, M.3
-
22
-
-
20044382799
-
Phase I clinical and pharmacokinetic study of the novel raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
DOI 10.1200/JCO.2005.06.124
-
Strumberg D, Richly H, Hilger RA, et al. Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol 2005;23:965-72 (Pubitemid 46202316)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.5
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
Schleucher, N.4
Korfee, S.5
Tewes, M.6
Faghih, M.7
Brendel, E.8
Voliotis, D.9
Haase, C.G.10
Schwartz, B.11
Awada, A.12
Voigtmann, R.13
Scheulen, M.E.14
Seeber, S.15
-
23
-
-
0141634089
-
Results of phase i pharmacokinetic and pharmacodynamic studies of the Raf kinase inhibitor BAY 43-9006 in patients with solid tumors
-
Strumberg D, Voliotis D, Moeller JG, et al. Results of phase I pharmacokinetic and pharmacodynamic studies of the Raf kinase inhibitor BAY 43-9006 in patients with solid tumors. Int J Clin Pharmacol Ther 2002;40:580-1
-
(2002)
Int J Clin Pharmacol Ther
, vol.40
, pp. 580-581
-
-
Strumberg, D.1
Voliotis, D.2
Moeller, J.G.3
-
24
-
-
32444439875
-
Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: Is rash associated with treatment outcome?
-
DOI 10.1016/j.ejca.2005.11.014, PII S0959804905010701
-
Strumberg D, Awada A, Hirte H, et al. Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: is rash associated with treatment outcome? Eur J Cancer 2006;42:548-56 (Pubitemid 43227936)
-
(2006)
European Journal of Cancer
, vol.42
, Issue.4
, pp. 548-556
-
-
Strumberg, D.1
Awada, A.2
Hirte, H.3
Clark, J.W.4
Seeber, S.5
Piccart, P.6
Hofstra, E.7
Voliotis, D.8
Christensen, O.9
Brueckner, A.10
Schwartz, B.11
-
25
-
-
33744984843
-
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.03.6723
-
Ratain MJ, Eisen T, Stadler WM, et al. Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 2006;24:2505-12 (Pubitemid 46630627)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2505-2512
-
-
Ratain, M.J.1
Eisen, T.2
Stadler, W.M.3
Flaherty, K.T.4
Kaye, S.B.5
Rosner, G.L.6
Gore, M.7
Desai, A.A.8
Patnaik, A.9
Xiong, H.Q.10
Rowinsky, E.11
Abbruzzese, J.L.12
Xia, C.13
Simantov, R.14
Schwartz, B.15
O'Dwyer, P.J.16
-
26
-
-
70350602665
-
Treatment and dosing patterns for angiogenesis inhibitor (AIS) therapies in patients with metastatic renal cell carcinoma (MRCC) [abstract 593P]
-
Choueiri TK, Brick AJ, McDermott S, et al. Treatment and dosing patterns for angiogenesis inhibitor (AIS) therapies in patients with metastatic renal cell carcinoma (MRCC) [abstract 593P]. Ann Oncol 2008;19(Suppl):viii191
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL.
-
-
Choueiri, T.K.1
Brick, A.J.2
McDermott, S.3
-
27
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007;356:125-34 (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
28
-
-
70249097380
-
Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial
-
Escudier B, Eisen T, Stadler WM, et al. Sorafenib for treatment of renal cell carcinoma: final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. J Clin Oncol 2009;27:3312-18
-
(2009)
J Clin Oncol
, vol.27
, pp. 3312-3318
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
29
-
-
34648863567
-
The advanced renal cell carcinoma sorafenib (ARCSS) expanded access trial in North America: Safety and efficacy [abstract 5011]. ASCO annual meeting proceedings, 43rd annual meeting
-
Knox JJ, Figlin RA, Stadler WM, et al. The advanced renal cell carcinoma sorafenib (ARCSS) expanded access trial in North America: safety and efficacy [abstract 5011]. ASCO Annual Meeting Proceedings, 43rd Annual Meeting. J Clin Oncol 2007;25:237S
-
(2007)
J Clin Oncol
, vol.25
-
-
Knox, J.J.1
Figlin, R.A.2
Stadler, W.M.3
-
30
-
-
77956084780
-
Safety and efficacy of sorafenib in elderly patients treated in the North American advanced renal cell carcinoma sorafenib expanded access program
-
Bukowski RM, Stadler WM, McDermott DF, et al. Safety and efficacy of sorafenib in elderly patients treated in the North American advanced renal cell carcinoma sorafenib expanded access program. Oncology 2010;78:340-7
-
(2010)
Oncology
, vol.78
, pp. 340-347
-
-
Bukowski, R.M.1
Stadler, W.M.2
McDermott, D.F.3
-
31
-
-
41149106110
-
A large open-label, non-comparative, phase III study of the multi-targeted kinase inhibitor sorafenib in European patients with advanced renal cell carcinoma [abstract 4506]
-
Beck J, Bajetta E, Escudier B, et al. A large open-label, non-comparative, phase III study of the multi-targeted kinase inhibitor sorafenib in European patients with advanced renal cell carcinoma [abstract 4506]. Eur J Cancer 2007;5(Suppl):300
-
(2007)
Eur J Cancer
, vol.5
, Issue.SUPPL.
, pp. 300
-
-
Beck, J.1
Bajetta, E.2
Escudier, B.3
-
32
-
-
56449118248
-
The medical treatment of metastatic renal cell cancer in the elderly: Position paper of a SIOG Taskforce
-
Bellmunt J, Negrier S, Escudier B, et al. The medical treatment of metastatic renal cell cancer in the elderly: position paper of a SIOG Taskforce. Crit Rev Oncol Hematol 2009;69:64-72
-
(2009)
Crit Rev Oncol Hematol
, vol.69
, pp. 64-72
-
-
Bellmunt, J.1
Negrier, S.2
Escudier, B.3
-
33
-
-
41149108218
-
Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma
-
Bhojani N, Jeldres C, Patard JJ, et al. Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. Eur Urol 2008;53:917-30
-
(2008)
Eur Urol
, vol.53
, pp. 917-930
-
-
Bhojani, N.1
Jeldres, C.2
Patard, J.J.3
-
34
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial. Lancet 2007;370:2103-11 (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
35
-
-
84876491007
-
-
Available from: [last accessed 1 January]
-
Pfizer. Sutent (Sunitinib) Prescribing information. 2007. Available from: http://www.pfizer.com/pfizer/download/uspi-sutent.pdf [last accessed 1 January 2012]
-
(2012)
Sutent (Sunitinib) Prescribing Information. 2007
-
-
-
36
-
-
50849094516
-
Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate
-
Telli ML, Witteles RM, Fisher GA, et al. Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate. Ann Oncol 2008;19:1613-18
-
(2008)
Ann Oncol
, vol.19
, pp. 1613-1618
-
-
Telli, M.L.1
Witteles, R.M.2
Fisher, G.A.3
-
37
-
-
48349122489
-
The clinical implications of sunitinib-induced hypothyroidism: A prospective evaluation
-
Wolter P, Stefan C, Decallonne B, et al. The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. Br J Cancer 2008;99:448-54
-
(2008)
Br J Cancer
, vol.99
, pp. 448-454
-
-
Wolter, P.1
Stefan, C.2
Decallonne, B.3
-
39
-
-
49249113484
-
Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity
-
Azad NS, Posadas EM, Kwitkowski VE, et al. Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncol 2008;26:3709-14
-
(2008)
J Clin Oncol
, vol.26
, pp. 3709-3714
-
-
Azad, N.S.1
Posadas, E.M.2
Kwitkowski, V.E.3
-
40
-
-
57649111897
-
Characterization of hyperglycemia, hypercholesterolemia, and hyperlipidemia in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha [abstract 5116]. ASCO annual meeting proceedings, 44th annual meeting
-
De Souza PL, Radulovic S, Beck J, et al. Characterization of hyperglycemia, hypercholesterolemia, and hyperlipidemia in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha [abstract 5116]. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26:278S
-
(2008)
J Clin Oncol
, vol.26
-
-
De Souza, P.L.1
Radulovic, S.2
Beck, J.3
-
41
-
-
84856243810
-
RAD001 vs placebo in patients with metastatic renal cell carcinoma (RCC) after progression on VEGFr-TKI therapy: Results from a randomized, double-blind, multicenter phase-III study [LBA 5026]. ASCO annual meeting proceedings, 44th annual meeting
-
Motzer RJ, Escudier B, Oudard S, et al. RAD001 vs placebo in patients with metastatic renal cell carcinoma (RCC) after progression on VEGFr-TKI therapy: results from a randomized, double-blind, multicenter phase-III study [LBA 5026]. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26
-
(2008)
J Clin Oncol
, vol.26
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
42
-
-
77953328875
-
Incidence of brain metastases in renal cell carcinoma treated with sorafenib
-
Massard C, Zonierek J, Gross-Goupil M, et al. Incidence of brain metastases in renal cell carcinoma treated with sorafenib. Ann Oncol 2010;21:1027-31
-
(2010)
Ann Oncol
, vol.21
, pp. 1027-1031
-
-
Massard, C.1
Zonierek, J.2
Gross-Goupil, M.3
-
43
-
-
77950814307
-
Angiogenesis inhibitor therapies for metastatic renal cell carcinoma: Effectiveness, safety and treatment patterns in clinical practice-based on medical chart review
-
Choueiri TK, Duh MS, Clement J, et al. Angiogenesis inhibitor therapies for metastatic renal cell carcinoma: effectiveness, safety and treatment patterns in clinical practice-based on medical chart review. BJU Int 2010;105:1247-54
-
(2010)
BJU Int
, vol.105
, pp. 1247-1254
-
-
Choueiri, T.K.1
Duh, M.S.2
Clement, J.3
-
44
-
-
79953075835
-
Safety and treatment patterns of multikinase inhibitors in patients with metastatic renal cell carcinoma at a tertiary oncology center in Italy
-
Porta C, Paglino C, Imarisio I, et al. Safety and treatment patterns of multikinase inhibitors in patients with metastatic renal cell carcinoma at a tertiary oncology center in Italy. BMC Cancer 2011;11:105
-
(2011)
BMC Cancer
, vol.11
, pp. 105
-
-
Porta, C.1
Paglino, C.2
Imarisio, I.3
-
45
-
-
65949118243
-
Combination targeted therapy in advanced renal cell carcinoma
-
Sosman J, Puzanov I. Combination targeted therapy in advanced renal cell carcinoma. Cancer 2009;115(10 Suppl):2368-75
-
(2009)
Cancer
, vol.115
, Issue.10 SUPPL.
, pp. 2368-2375
-
-
Sosman, J.1
Puzanov, I.2
-
46
-
-
55349098735
-
Updated results of a phase i trial of sorafenib and bevacizumab in patients with metastatic renal cell cancer [abstract 5011]. ASCO annual meeting proceedings, 44th annual meeting
-
Sosman JA, Flaherty KT, Atkins MB, et al. Updated results of a phase I trial of sorafenib and bevacizumab in patients with metastatic renal cell cancer [abstract 5011]. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26:252S
-
(2008)
J Clin Oncol
, vol.26
-
-
Sosman, J.A.1
Flaherty, K.T.2
Atkins, M.B.3
-
47
-
-
67249106104
-
Phase i study of sorafenib and RAD001 for metastatic clear cell renal cell carcinoma [abstract 5109]. ASCO annual meeting proceedings, 44th annual meeting
-
Rosenberg JE, Weinberg VK, Claros C, et al. Phase I study of sorafenib and RAD001 for metastatic clear cell renal cell carcinoma [abstract 5109]. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26:276S
-
(2008)
J Clin Oncol
, vol.26
-
-
Rosenberg, J.E.1
Weinberg, V.K.2
Claros, C.3
-
48
-
-
84856270577
-
A phase i study with a daily regimen of the mTOR inhibitor RAD001 (everolimus) plus sorafenib for patients with metastatic renal cell cancer (mRCC) [abstract 14603]. ASCO annual meeting proceedings, 44th annual meeting
-
Giessinger S, Amato RJ, Jac J, et al. A phase I study with a daily regimen of the mTOR inhibitor RAD001 (everolimus) plus sorafenib for patients with metastatic renal cell cancer (mRCC) [abstract 14603]. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26:635S
-
(2008)
J Clin Oncol
, vol.26
-
-
Giessinger, S.1
Amato, R.J.2
Jac, J.3
-
49
-
-
36849031075
-
A phase I, pharmacokinetic and pharmacodynamic study of sorafenib, a multi-targeted kinase inhibitor in combination with temsirolimus, an mTOR inhibitor in patients with advanced solid malignancies [abstract 3512]. ASCO annual meeting proceedings, 43rd annual meeting
-
Patnaik A, Ricart A, Cooper J, et al. A phase I, pharmacokinetic and pharmacodynamic study of sorafenib, a multi-targeted kinase inhibitor in combination with temsirolimus, an mTOR inhibitor in patients with advanced solid malignancies [abstract 3512]. ASCO Annual Meeting Proceedings, 43rd Annual Meeting. J Clin Oncol 2007;25:141S
-
(2007)
J Clin Oncol
, vol.25
-
-
Patnaik, A.1
Ricart, A.2
Cooper, J.3
-
50
-
-
80255135379
-
AMG 386 in combination with sorafenib in patients with metastatic renal cell cancer (mRCC): A randomized, double-blind, placebo-controlled, phase II study
-
abstract 309
-
Rini BI, Szczylik C, Tannir NM, et al. AMG 386 in combination with sorafenib in patients with metastatic renal cell cancer (mRCC): a randomized, double-blind, placebo-controlled, phase II study. J Clin Oncol 2011;29(Suppl 7):abstract 309
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 7
-
-
Rini, B.I.1
Szczylik, C.2
Tannir, N.M.3
-
51
-
-
79954438593
-
Sorafenib with interleukin-2 vs sorafenib alone in metastatic renal cell carcinoma: The ROSORC trial
-
Procopio G, Verzoni E, Bracarda S, et al. Sorafenib with interleukin-2 vs sorafenib alone in metastatic renal cell carcinoma: the ROSORC trial. Br J Cancer 2011;104:1256-61
-
(2011)
Br J Cancer
, vol.104
, pp. 1256-1261
-
-
Procopio, G.1
Verzoni, E.2
Bracarda, S.3
-
52
-
-
34548263735
-
Phase II trial of sorafenib plus interferon alfa-2b as first- or second-line therapy in patients with metastatic renal cell cancer
-
DOI 10.1200/JCO.2007.10.8613
-
Gollob JA, Rathmell WK, Richmond TM, et al. Phase II trial of sorafenib plus interferon alfa-2b as firstor second-line therapy in patients with metastatic renal cell cancer. J Clin Oncol 2007;25:3288-95 (Pubitemid 47325614)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.22
, pp. 3288-3295
-
-
Gollob, J.A.1
Rathmell, W.K.2
Richmond, T.M.3
Marino, C.B.4
Miller, E.K.5
Grigson, G.6
Watkins, C.7
Gu, L.8
Peterson, B.L.9
Wright, J.J.10
-
53
-
-
36749064602
-
Antitumor Effects of Sunitinib or Sorafenib in Patients With Metastatic Renal Cell Carcinoma Who Received Prior Antiangiogenic Therapy
-
DOI 10.1016/j.juro.2007.08.127, PII S0022534707022938
-
Tamaskar I, Garcia JA, Elson P, et al. Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy. J Urol 2008;179:81-6.discussion 6 (Pubitemid 350216728)
-
(2008)
Journal of Urology
, vol.179
, Issue.1
, pp. 81-86
-
-
Tamaskar, I.1
Garcia, J.A.2
Elson, P.3
Wood, L.4
Mekhail, T.5
Dreicer, R.6
Rini, B.I.7
Bukowski, R.M.8
-
54
-
-
70350602664
-
Second line treatment of progressive metastatic renal cell cancer with temsirolimus following first-line therapy with sunitinib or sorafenib [abstract V684]
-
Richter S, Pfister D, Thuer D, et al. Second line treatment of progressive metastatic renal cell cancer with temsirolimus following first-line therapy with sunitinib or sorafenib [abstract V684]. Onkologie 2009;31(Suppl):324
-
(2009)
Onkologie
, vol.31
, Issue.SUPPL.
, pp. 324
-
-
Richter, S.1
Pfister, D.2
Thuer, D.3
-
55
-
-
74949115821
-
Phase II dose escalation study of sorafenib in patients with metastatic renal cell carcinoma (mRCC) who have had prior treatment with VEGFR-TKI antiangiogenic treatment. ASCO annual meeting proceedings, 45th annual meeting
-
abstract e16027
-
Mancuso AP, Donato De Paola E, Catalano A, et al. Phase II dose escalation study of sorafenib in patients with metastatic renal cell carcinoma (mRCC) who have had prior treatment with VEGFR-TKI antiangiogenic treatment. ASCO Annual Meeting Proceedings, 45th Annual Meeting. J Clin Oncol 2009;27:abstract e16027
-
(2009)
J Clin Oncol
, vol.27
-
-
Mancuso, A.P.1
Donato De Paola, E.2
Catalano, A.3
-
56
-
-
67649649641
-
Sorafenib as a second-line and sequential therapy for patients with metastatic renal cell carcinoma (mRCC): Analysis for safety and activity on sunitinib progressive patients. ASCO annual meeting proceedings, 44th annual meeting
-
abstract 16100
-
Sepulveda J, Maroto P, Andres R, et al. Sorafenib as a second-line and sequential therapy for patients with metastatic renal cell carcinoma (mRCC): analysis for safety and activity on sunitinib progressive patients. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26:abstract 16100
-
(2008)
J Clin Oncol
, vol.26
-
-
Sepulveda, J.1
Maroto, P.2
Andres, R.3
-
57
-
-
62849099971
-
Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib
-
Zimmermann K, Schmittel A, Steiner U, et al. Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib. Oncology 2009;76:350-4
-
(2009)
Oncology
, vol.76
, pp. 350-354
-
-
Zimmermann, K.1
Schmittel, A.2
Steiner, U.3
-
58
-
-
55649103188
-
Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: A retrospective outcome analysis
-
Eichelberg C, Heuer R, Chun FK, et al. Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis. Eur Urol 2008;54:1373-8
-
(2008)
Eur Urol
, vol.54
, pp. 1373-1378
-
-
Eichelberg, C.1
Heuer, R.2
Chun, F.K.3
-
59
-
-
58949092548
-
Sequential therapy with sorafenib and sunitinib in renal cell carcinoma
-
Dudek AZ, Zolnierek J, Dham A, et al. Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. Cancer 2009;115:61-7
-
(2009)
Cancer
, vol.115
, pp. 61-67
-
-
Dudek, A.Z.1
Zolnierek, J.2
Dham, A.3
-
60
-
-
67349163859
-
Sequential sorafenib and sunitinib for renal cell carcinoma
-
discussion
-
Sablin MP, Negrier S, Ravaud A, et al. Sequential sorafenib and sunitinib for renal cell carcinoma. J Urol 2009;182:29-34.discussion
-
(2009)
J Urol
, vol.182
, pp. 29-34
-
-
Sablin, M.P.1
Negrier, S.2
Ravaud, A.3
-
61
-
-
67650659867
-
Retrospective analysis of the sequential use of sorafenib and sunitinib in patients with advanced renal cell carcinoma (RCC)
-
abstract 252
-
Porta C, Procopio G, Sabbatini R, et al. Retrospective analysis of the sequential use of sorafenib and sunitinib in patients with advanced renal cell carcinoma (RCC). Eur Urol 2009;8(Suppl 4):abstract 252
-
(2009)
Eur Urol
, vol.8
, Issue.SUPPL. 4
-
-
Porta, C.1
Procopio, G.2
Sabbatini, R.3
-
62
-
-
84856362744
-
Sunitinib followed by sorafenib or vice versa for metastatic renal cell carcinoma - Data from the Czech registry
-
Epub ahead of print 2 May; doi: 10.1093/annonc/mdr065
-
Buchler T, Klapka R, Melichar B, et al. Sunitinib followed by sorafenib or vice versa for metastatic renal cell carcinoma - data from the Czech registry. Ann Oncol [Epub ahead of print 2 May 2011; doi: 10.1093/annonc/mdr065]
-
(2011)
Ann Oncol
-
-
Buchler, T.1
Klapka, R.2
Melichar, B.3
-
63
-
-
80255141916
-
Sequence therapy in patients with metastatic renal cell carcinoma: Comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors
-
Busch J, Seidel C, Kempkensteffen C, et al. Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors. Eur Urol 2011;60:1163-70
-
(2011)
Eur Urol
, vol.60
, pp. 1163-1170
-
-
Busch, J.1
Seidel, C.2
Kempkensteffen, C.3
-
64
-
-
79957504870
-
Sequential therapies with sorafenib and sunitinib in advanced or metastatic renal cell carcinoma
-
Herrmann E, Marschner N, Grimm MO, et al. Sequential therapies with sorafenib and sunitinib in advanced or metastatic renal cell carcinoma. World J Urol 2011;29:361-6
-
(2011)
World J Urol
, vol.29
, pp. 361-366
-
-
Herrmann, E.1
Marschner, N.2
Grimm, M.O.3
-
66
-
-
65549155468
-
A multicenter prospective trial of sorafenib in patients with metastatic clear cell renal cell carcinoma (mccRCC) refractory to prior sunitinib or bevacizumab [abstract 5123]. ASCO annual meeting proceedings, 44th annual meeting
-
Shepard DR, Rini RI, Garcia JA, et al. A multicenter prospective trial of sorafenib in patients with metastatic clear cell renal cell carcinoma (mccRCC) refractory to prior sunitinib or bevacizumab [abstract 5123]. ASCO Annual Meeting Proceedings, 44th Annual Meeting. J Clin Oncol 2008;26:280S
-
(2008)
J Clin Oncol
, vol.26
-
-
Shepard, D.R.1
Rini, R.I.2
Garcia, J.A.3
-
67
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009;15:220-31
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
|