Methylenetetrahydrofolate reductase gene polymorphisms in Turkish children with attention-deficit/hyperactivity disorder

Genetic Testing and Molecular Biomarkers

Volumn 16, Issue 1, 2012, Pages 67-69

  Ergul, Emel ^a   Sazci, Ali ^a   Kara, Ihsan ^b  

^a KOCAELI UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TURKEY (REPUBLIC);

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, SINGLE NUCLEOTIDE; TURKEY;

EID: 84856242112     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2011.0062     Document Type: Article

References (17)

1. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edition (DSM-IV). American Psychiatric Association Washington, DC.
2. Bobb AJ, Castellanos FX, Addington AM, Rapoport JL (2005) Molecular genetic studies of ADHD: 1991 to 2004. Am J Med Genet B Neuropsychiatry Genet 132:109-125. (Pubitemid 40066207)
3. Faraone SV, Sergeant J, Gillberg C, Biederman J (2003) The worldwide prevalence of ADHD: is it an American condition? World Psychiatry 2:104-113.
4. Franke B, Neale BM, Faraone SV (2009) Genome-wide association studies in ADHD. Hum Genet 126:13-50.
5. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, van den Heuvel LP, Rozen R (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10:111-113.
6. Kara I, Sazci A, Ergul E, Kaya G, Kilic G (2003) Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk. Mol Brain Res 111:84-90. (Pubitemid 36332332)
7. Kempisty B, Bober A, quczak M, Czerski P, Szczepankiewicz A, Hauser J, Jagodziński PP (2007) Distribution of 1298A >C polymorphism of methylenetetrahydrofolate reductase gene in patients with bipolar disorder and schizophrenia. Eur Psychiatry 22:39-43. (Pubitemid 46162184)
8. Krajinovic M, Robaey P, Chiasson S, Lemieux-Blanchard E, Rouillard M, Primeau M., Bournissen FG, Moghrabi A (2005) Polymorphisms of genes controlling homocysteine levels and IQ score following the treatment for childhood ALL. Pharmacogenomics 6:293-302. (Pubitemid 40601632)
9. Krull KR, Brouwers P, Jain N, Zhang L, Bomgaars L, Dreyer Z, Mahoney D, Bottomley S, Okcu MF (2008) Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors. J Pediatr 152:101-105. (Pubitemid 350265921)
10. Mill J, Petronis A (2008) Pre- and peri-natal environmental risks for attention-deficit hyperactivitydisorder (ADHD): the potential role of epigenetic processes in mediating susceptibility. J Child Psychol Psychiatry 49:1020-1030.
11. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215.
12. Nøvik TS, Hervas A, Ralston SJ, Dalsgaard S, Rodrigues Pereira R, Lorenzo MJ; ADORE Study Group (2006) Influence of gender on attention-deficit/ hyperactivity disorder in Europe-ADORE. Eur Child Adolesc Psychiatry Suppl 1:I15-I24.
13. Sazci A, Ergul E, Guzelhan Y, Kaya G, Kara I (2003) Methylenetetrahydrofolate reductase gene polymorphisms in patients with schizophrenia. Mol Brain Res 117:104-107. (Pubitemid 37123116)
14. Sazci A, Ergul E, Kucukali I, Kara I, Kaya G (2005) Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: association is significant in men but not in women. Prog Neuropsychopharmacol. Biol Psychiatry 29:1113-1123. (Pubitemid 41383510)
15. Scahill L, Schwab-Stone M (2000) Epidemiology of ADHD in school-age children. Child Adolesc Psychiatr Clin N Am 9:541-555. (Pubitemid 30620543)
16. Wallis D, Russell HF, Muenke M (2008) Review: genetics of attention deficit/hyperactivity disorder. J Pediatr Psychol 33:1085-1099.
17. Weisberg I, Tran P, Christensen B, Sibani S, Rozen R (1998) A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 64:169-172. (Pubitemid 28453294)