Evaluation of a novel ELISA for serotonin: Urinary serotonin as a potential biomarker for depression

Analytical and Bioanalytical Chemistry

Volumn 402, Issue 4, 2012, Pages 1593-1600

  Nichkova, Mikaela I ^a   Huisman, Han ^a   Wynveen, Paul M ^a   Marc, David T ^b   Olson, Kelly L ^b   Kellermann, Gottfried H ^b  

^a Pharmasan Labs Inc   (United States)

^b NeuroScience Inc   (United States)

Author keywords

5 Hydroxytryptamine; Antidepressants; Depression; ELISA; Immunoassay; Urine

Indexed keywords

5-HYDROXYTRYPTAMINE; ANTIDEPRESSANTS; DEPRESSION; ELISA; IMMUNOASSAY; URINE;

AMINO ACIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BODY FLUIDS;

ANTIDEPRESSANT AGENT; BIOLOGICAL MARKER; SEROTONIN;

ADOLESCENT; ADULT; AGED; ARTICLE; DEPRESSION; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; FEMALE; HUMAN; LIMIT OF DETECTION; MALE; METHODOLOGY; MIDDLE AGED; STATISTICAL MODEL; URINE;

ADOLESCENT; ADULT; AGED; ANTIDEPRESSIVE AGENTS; BIOLOGICAL MARKERS; DEPRESSIVE DISORDER; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LIMIT OF DETECTION; LINEAR MODELS; MALE; MIDDLE AGED; SEROTONIN; YOUNG ADULT;

EID: 84856228692     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5583-1     Document Type: Article

References (36)

1. DT Marc JW Ailts DC Ailts-Campeau MJ Bull O Kl 2011 Neurotransmitters excreted in the urine as biomarkers of nervous system activity: validity and clinical applicability Neurosci Biobehav Rev 35 635 644 10.1016/j.neubiorev. 2010.07.007 1:CAS:528:DC%2BC3cXhsFCrurrE
2. MD Berry 2004 Mammalian central nervous system trace amines. Pharmacologic amphetamines, physiologic neuromodulators J Neurochem 90 257 271 10.1111/j.1471-4159.2004.02501.x 1:CAS:528:DC%2BD2cXmtVyrsbk%3D (Pubitemid 38938212)
3. IP Kema EG de Vries FA Muskiet 2000 Clinical chemistry of serotonin and metabolites J Chrom B 747 33 48 10.1016/S0378-4347(00)00341-8 1:CAS:528:DC%2BD3cXmvFylu7o%3D
4. DE Nichols CD Nichols 2008 Serotonin receptors Chem Rev 108 1614 1641 10.1021/cr078224o 1:CAS:528:DC%2BD1cXlslOisL8%3D (Pubitemid 351796401)
5. V Krishnan EJ Nestler 2010 Linking molecules to mood: new insight into the biology of depression Am J Psychiatry 167 1305 1320 10.1176/appi.ajp.2009. 10030434
6. IA Cook 2008 Biomarkers in psychiatry: potentials pitfalls and pragmatics Prim Psychiatr 15 54 59
7. ME Berman JI Tracy EF Coccaro 1997 The serotonin hypothesis of aggression revisited Clin Psychol Rev 17 651 665 10.1016/S0272-7358(97)00039-1 1:STN:280:DyaK2svnslOmtA%3D%3D (Pubitemid 127363434)
8. SC Risch CB Nemeroff 1992 Neurochemical alterations of serotonergic neuronal systems in depression J Clin Psychiatry 53 3 7
9. HM van Praag 1981 Management of depression with serotonin precursors Biol Psychiatry 16 291 310 (Pubitemid 11154883)
10. EH Cook BL Leventhal 1996 The serotonin system in autism Curr Opin Pediatr 8 348 354 10.1097/00008480-199608000-00008 1:STN:280: DyaK2s7pslCqtQ%3D%3D (Pubitemid 26393877)
11. GM Anderson 2002 Genetics of childhood disorders: XLV. Autism, part 4: serotonin in autism J Am Acad Child Adolesc Psychiatr 41 1513 1516 10.1097/00004583-200212000-00025 (Pubitemid 44698530)
12. EJ Mulder GM Anderson RFJ Kemperman A Oosterloo-Duinkerken RB Minderaa IP Kema 2010 Urinary excretion of 5-hydroxyindoleacetic acid, serotonin and 6-sulphatoxymelatonin in normoserotonemic and hyperserotonemic austistic individuals Neuropsychobiology 61 27 32 10.1159/000258640 1:CAS:528: DC%2BD1MXhsF2gtrvK
13. EH Turner JM Loftis AD Blackwell 2006 Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan Pharmacol Therapeut 109 325 338 10.1016/j.pharmthera.2005.06.004 1:CAS:528: DC%2BD28Xnslylsg%3D%3D (Pubitemid 43132816)
14. S Russo IP Kema F Bosker J Haavik J Korf 2009 Tryptophan as an evolutionarily conserved signal to brain serotonin: molecular evidence and psychiatric implications World J Biol Psychiatry 10 258 268 10.3109/ 15622970701513764
15. N Kotzailias M Marker B Jilma 2004 Early effects of paroxetine on serotonin storage, plasma levels and urinary excretion J Clin Psychopharmacol 24 536 539 10.1097/01.jcp.0000138765.08235.46 1:CAS:528:DC%2BD2cXnt1Oqs70%3D (Pubitemid 39274209)
16. K Hyland 2008 Clinical utility of monoamine neurotransmitter metabolite analysis in cerebrospinal fluid Clin Chem 54 633 641 10.1373/clinchem.2007. 099986 1:CAS:528:DC%2BD1cXkt1equro%3D (Pubitemid 351573703)
17. GM Anderson IN Mefford TJ Tolliver MA Riddle DM Ocame JF Leckman DJ Cohen 1990 Serotonin in human lumbar cerebrospinal fluid: a reassessment Life Sci 46 247 255 10.1016/0024-3205(90)90030-U 1:CAS:528:DyaK3cXpt1eruw%3D%3D (Pubitemid 20038356)
18. WHA De Jong MHLI Wilkens EGE De Vries IP Kema 2010 Automated mass spectrometric analysis of urinary and plasma serotonin Anal Bioanal Chem 396 2609 2616 10.1007/s00216-010-3466-5
19. E Pussard N Guigueno O Adam JF Giudicelli 1996 Validation of HPLC-amperometric detection to measure serotonin in plasma, platelets, whole blood, and urine Clin Chem 42 1086 1091 1:CAS:528:DyaK28XktFWmsLo%3D (Pubitemid 26231416)
20. JM Feldman 1986 Urinary serotonin in the diagnosis of carcinoid tumors Clin Chem 32 840 844 1:STN:280:DyaL287ptVGisQ%3D%3D (Pubitemid 17028362)
21. B Manz H Kosfeld G Harbauer HJ Grill K Pollow 1985 Radioimmunoassay of human serum serotonin J Clin Chem Clin Biochem 10 657 662 (Pubitemid 16242096)
22. J Chauveau V Fert AM Morel MA Delaage 1991 Rapid and specific enzyme immunoassay of serotonin Clin Chem 37 1178 1184 1:CAS:528:DyaK3MXkvVGmtL4%3D (Pubitemid 21925943)
23. H Huisman P Wynveen PW Setter 2010 Studies on the immune response and preparation of antibodies against a large panel of conjugated neurotransmitters and biogenic amines: specific polyclonal antibody response and tolerance J Neurochem 112 829 841 10.1111/j.1471-4159.2009.06492.x 1:CAS:528: DC%2BC3cXht1erurc%3D
24. LR Derogatis RS Lipman K Rickels EH Uhlenhuth L Covi 1974 The Hopkins Symptom Checklist (HSCL): a self-report symptom inventory Behav Sci 19 1 15 10.1002/bs.3830190102 1:STN:280:DyaE2c%2FltlOquw%3D%3D
25. LR Derogatis RS Lipman K Rickels EH Uhlenhuth L Covi 1974 The Hopkins Symptom Checklist (HSCL). A measure of primary symptom dimensions Mod Probl Pharmacopsychiatr 7 79 110 1:STN:280:DyaE2M%2Fhs1yitQ%3D%3D
26. RM Glass T Allan EH Uhlenhut CP Kimball DI Borinsetin 1978 Psychiatric screening in a medical clinic: an evaluation of a self-report inventory Arch Gen Psychiatry 35 1189 1195 10.1001/archpsyc.1978.01770340039003 1:STN:280:DyaE1M%2FitVCjtg%3D%3D (Pubitemid 9006025)
27. H Huisman P Wynveen M Nichkova G Kellermann 2010 Novel ELISAs for screening of the biogenic amines GABA, glycine, beta-phenylethylamine, agmatine, and taurine using one derivatization procedure of whole urine samples Anal Chem 82 6526 6533 10.1021/ac100858u 1:CAS:528:DC%2BC3cXotFKmsL0%3D
28. OM Poulsen E Holst JM Christensen 1997 Calculation and application of coverage intervals for biological reference values Pure Appl Chem 69 1601 1601 1611 10.1351/pac199769071601 1:CAS:528:DyaK2sXltFSmtr8%3D
29. R Grasbeck N Montalbetti C PetitClerc G Siest HE Solberg D Stamm P Wilding M Hjelm MHJ Leyssen L Tentori RL Verwilghen 1987 Approved recommendation on the theory of reference values. Part 5. Statistical treatment of collected reference values. Determination of reference limits Clin Chim Acta 170 S13 10.1016/0009-8981(87)90151-3
30. Clinical and Laboratory Standards Institute. Evaluation of the linearity of quantitative measurement procedures: a statistical approach; approved guideline. CLSI document EP6, 2003.
31. Clinical and Laboratory Standards Institute. Interference testing in clinical chemistry; approved guideline (2005) Second Edition. CLSI document EP7-A2, vol. 25, no. 27.
32. CM Masi EM Rickett LC Hawkley JT Cacioppo 2004 Gender and ethnic differences in urinary stress hormones: the population-based Chicago health, aging, and social relations study J Appl Physiol 97 941 947 10.1152/ japplphysiol.00256.2004 1:CAS:528:DC%2BD2cXnvVOrsLY%3D (Pubitemid 39121417)
33. JD Ropero-Miller H Paget-Wilkes PL Doering BA Goldberger 2000 Effect of oral creatinine supplementation on random urine creatinine, pH, and specific gravity measurements Clin Chem 46 295 297 1:CAS:528:DC%2BD3cXjvFGhtbg%3D (Pubitemid 30104260)
34. KH Le Quan-Bui O Plaisant M Leboyer C Gay L Kamal MA Devynck P Meyer 1984 Reduced platelet serotonin in depression Psychiatr Res 13 129 139 10.1016/0165-1781(84)90056-8 (Pubitemid 15214171)
35. M Vaswani FK Linda S Ramesh 2003 Role of selective serotonin reuptake inhibitors in psychiatry disorders: a comprehensive review Prog Neuropsychopharmacol Biol Psychiatry 27 85 102 10.1016/S0278-5846(02)00338-X 1:CAS:528:DC%2BD3sXmsFakuw%3D%3D (Pubitemid 36131110)
36. TC Li Kam Wa NJT Burns BC Williams S Freestone MR Lee 1995 Blood and urine 5-hydroxytrypthophan and 5-hydroxytryptamine levels after administration of two 5-hydroxytryptamine precursors in normal man Br J Clin Pharmacol 39 327 329 1:CAS:528:DyaK2MXkvVGmtr8%3D