Serum ferritin level is associated with the prevalence of metabolic syndrome in Korean adults: The 2007-2008 Korean National Health and Nutrition Examination Survey

Clinica Chimica Acta

Volumn 413, Issue 5-6, 2012, Pages 636-641

  Kang, Hee Taik ^a,b   Linton, John A ^c   Shim, Jae Yong ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

Ferritin; Inflammation; Insulin resistance; Metabolic syndrome; Oxidative stress

Indexed keywords

FERRITIN; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; ETHNIC GROUP; FEMALE; FERRITIN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HUMAN; INSULIN RESISTANCE; KOREAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PREVALENCE; PRIORITY JOURNAL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE;

ADULT; FEMALE; FERRITINS; HEALTH SURVEYS; HUMANS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; REPUBLIC OF KOREA;

EID: 84856224129     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2011.12.011     Document Type: Article

References (28)

1. Eckel R.H., Grundy S.M., Zimmet P.Z. The metabolic syndrome. Lancet 2005, 365:1415-1428.
2. Yoon Y.S., Lee E.S., Park C., Lee S., Oh S.W. The new definition of metabolic syndrome by the international diabetes federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised national cholesterol education program: the Korea NHANES study. Int J Obes (Lond) 2007, 31:528-534.
3. Lann D., LeRoith D. Insulin resistance as the underlying cause for the metabolic syndrome. Med Clin North Am 2007, 91:1063-1077.
4. Furukawa S., Fujita T., Shimabukuro M., et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 2004, 114:1752-1761.
5. Rutter M.K., Meigs J.B., Sullivan L.M., D'Agostino R.B., Wilson P.W. C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 2004, 110:380-385.
6. Gabay C., Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999, 340:448-454.
7. Fearon I.M., Faux S.P. Oxidative stress and cardiovascular disease: novel tools give (free) radical insight. J Mol Cell Cardiol 2009, 47:372-381.
8. Gonzalez A.S., Guerreno D.B., Soto M.B., Diaz S.P., Martinez-Olmos M., Vidal O. Metabolic syndrome, insulin resistance and the inflammation markers C-reactive protein and ferritin. Eur J Clin Nutr 2006, 60:802-809.
9. Williams M.J., Poulton R., Williams S. Relationship of serum ferritin with cardiovascular risk factors and inflammation in young men and women. Atherosclerosis 2002, 165:179-184.
10. Wilson J.G., Lindquist J.H., Grambow S.C., Crook E.D., Maher J.F. Potential role of increased iron stores in diabetes. Am J Med Sci 2003, 325:332-339.
11. Ferrannini E. Insulin resistance, iron, and the liver. Lancet 2000, 355:2181-2182.
12. Jiang R., Manson J.E., Meigs J.B., Ma J., Rifai N., Hu F.B. Body iron stores in relation to risk of type 2 diabetes in apparently healthy women. JAMA 2004, 291:711-717.
13. Piperno A., Trombini P., Gelosa M., et al. Increased serum ferritin is common in men with essential hypertension. J Hypertens 2002, 20:1513-1518.
14. Halle M., Konig D., Berg A., Keul J., Baumstark M.W. Relationship of serum ferritin concentrations with metabolic cardiovascular risk factors in men without evidence for coronary artery disease. Atherosclerosis 1997, 128:235-240.
15. Gillum R.F. Association of serum ferritin and indices of body fat distribution and obesity in Mexican American men-the Third National Health and Nutrition Examination Survey. Int J Obes Relat Metab Disord 2001, 25:639-645.
16. Mateo-Gallego R., Calmarza P., Jarauta E., Burillo E., Cenarro A., Civeira F. Serum ferritin is a major determinant of lipid phenotype in familial combined hyperlipidemia and familial hypertriglyceridemia. Metabolism 2010, 59:154-158.
17. Kim C.H., Kim H.K., Bae S.J., Park J.Y., Lee K.U. Association of elevated serum ferritin concentration with insulin resistance and impaired glucose metabolism in Korean men and women. Metabolism 2011, 60:414-420.
18. Grundy S.M., Cleeman J.I., Danels S.R., et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112:2735-2752.
19. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
20. Evans J.L., Maddux B.A., Goldfine I.D. The molecular basis for oxidative stress-induced insulin resistance. Antioxid Redox Signal 2005, 7:1040-1052.
21. Ford E.S., Mokdad A.H., Giles W.H., Brown D.W. The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey. Diabetes 2003, 52:2346-2352.
22. Mukherjee S.P., Lynn W.S. Reduced nicotinamide adenine dinucleotide phosphate oxidase in adipocyte plasma membrane and its activation by insulin. Possible role in the hormone's effects on adenylate cyclase and the hexose monophosphate shunt. Arch Biochem Biophys 1977, 184:69-76.
23. Merkel P.A., Simonson D.C., Amiel S.A., et al. Insulin resistance and hyperinsulinemia in patients with thalassemia major treated by hypertransfusion. N Engl J Med 1988, 318:809-814.
24. Yao D., Shi W., Gou Y., et al. Fatty acid-mediated intracellular iron translocation: a synergistic mechanism of oxidative injury. Free Radic Biol Med 2005, 39:1385-1398.
25. Valko M., Leibfritz D., Moncol J., Cronin M.T., Mazur M., Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007, 39:44-84.
26. Jehn M., Clark J.M., Guallar E. Serum ferritin and risk of the metabolic syndrome in U.S. adults. Diabetes Care 2004, 27:2422-2428.
27. Davis R.J., Corvera S., Czech M.P. Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane. J Biol Chem 1986, 261:8708-8711.
28. Lee J.Y., Yoo K.H., Hahn S.H. HFE gene mutation, C282Y causing hereditary hemochromatosis in Caucasian is extremely rare in Korean population. J Korean Med Sci 2000, 15:179-182.