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Volumn 402, Issue 3, 2012, Pages 1249-1255
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Qualitative studies on the metabolism and the toxicological detection of the fentanyl-derived designer drugs 3-methylfentanyl and isofentanyl in rats using liquid chromatography-linear ion trap-mass spectrometry (LC-MS n)
a
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Author keywords
3 Methylfentanyl; CYP isoenzymes; Isofentanyl; LC MS; Metabolism; Rat urine
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Indexed keywords
3-METHYLFENTANYL;
BENZYL MOIETIES;
CLANDESTINE LABORATORIES;
CYP2C19;
CYTOCHROME P450;
DESIGNER DRUGS;
DETECTABILITY;
FENTANYLS;
FIVE PHASE;
FOUR-PHASE;
GLUCURONIDES;
HIGH POTENCY;
HYDROXY METABOLITES;
ION-TRAP MASS SPECTROMETRY;
ISOFENTANYL;
LC-MS;
LC-MS N;
N-DEALKYLATION;
N-OXIDATION;
NINE-PHASE;
PHASE I;
PHASE II;
QUALITATIVE STUDY;
RAT URINE;
SCREENING APPROACHES;
SIDE-CHAINS;
ALKYLATION;
ANESTHETICS;
BIOMOLECULES;
BODY FLUIDS;
CARBOXYLIC ACIDS;
DESIGN;
DRUG DOSAGE;
ELECTRON TRAPS;
HYDROXYLATION;
ISOENZYMES;
LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETRY;
METABOLITES;
PHYSIOLOGY;
RATS;
METABOLISM;
3-METHYLFENTANYL;
CYTOCHROME P450;
DESIGNER DRUG;
DRUG DERIVATIVE;
FENTANYL;
ISOFENTANYL;
MEFENTANYL;
NARCOTIC ANALGESIC AGENT;
ANIMAL;
ARTICLE;
LIQUID CHROMATOGRAPHY;
MALE;
MASS SPECTROMETRY;
METABOLISM;
METHODOLOGY;
RAT;
URINE;
WISTAR RAT;
ANALGESICS, OPIOID;
ANIMALS;
CHROMATOGRAPHY, LIQUID;
CYTOCHROME P-450 ENZYME SYSTEM;
DESIGNER DRUGS;
FENTANYL;
MALE;
MASS SPECTROMETRY;
RATS;
RATS, WISTAR;
RATTUS;
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EID: 84856220952
PISSN: 16182642
EISSN: 16182650
Source Type: Journal
DOI: 10.1007/s00216-011-5528-8 Document Type: Article |
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Times cited : (37)
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References (17)
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