Metabolic activation of sulfur mustard leads to oxygen free radical formation

Free Radical Biology and Medicine

Volumn 52, Issue 4, 2012, Pages 811-817

  Brimfield, A A ^a   Soni, S D ^a   Trimmer, K A ^a   Zottola, M A ^a   Sweeney, R E ^a   Graham, J S ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Free radical; Mechanism; Reactive oxygen species; Redox cycling; Sulfur mustard

Indexed keywords

5 TERT BUTOXYCARBONYL 5 METHYLPYRROLINE N OXIDE; CARBON; CATALASE; CYTOCHROME P450 REDUCTASE; HERBICIDE; HYDROXYL RADICAL; OXYGEN RADICAL; PEROXY RADICAL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFONIUM DERIVATIVE; SULFUR; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; DEOXYGENATION; ELECTRON SPIN RESONANCE; IN VITRO STUDY; METABOLIC ACTIVATION; MUSTARD; PRIORITY JOURNAL; QUANTUM MECHANICS; SIGNAL TRANSDUCTION;

ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; KINETICS; MODELS, CHEMICAL; MUSTARD GAS; NADP; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; OXYGEN; POLYPROPYLENES; PYRIDINES; REACTIVE OXYGEN SPECIES; SPIN LABELS;

EID: 84856219860     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.11.031     Document Type: Article

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