Gradual pore formation in natural origin scaffolds throughout subcutaneous implantation

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 3, 2012, Pages 599-612

  Martins, Ana M ^a,b   Kretlow, James D ^b   Costa Pinto, Ana R ^a   Malafaya, Patrícia B ^a   Fernandes, Emanuel M ^a   Neves, Nuno M ^a   Alves, Catarina M ^a   Mikos, Antonios G ^b   Kasper, F Kurtis ^b   Reis, Rui L ^a  

^a UNIVERSITY OF MINHO   (Portugal)

^b Rice University   (United States)

Author keywords

enzymes; in situ pore formation; in vivo degradation; natural origin materials; tissue response

Indexed keywords

CELLULAR INGROWTH; EXPERIMENTAL GROUPS; FUNCTION OF TIME; HISTOLOGICAL ANALYSIS; IMPLANTATION MODELS; IN VIVO DEGRADATION; IN-SITU; IN-VIVO; MICROCOMPUTED TOMOGRAPHY; PORE FORMATION; SCAFFOLD DEGRADATION; TIME POINTS; TISSUE REACTIONS; TISSUE RESPONSE; WEIGHT LOSS;

BIOMIMETICS; CALCIUM PHOSPHATE; CHITOSAN; COMPUTERIZED TOMOGRAPHY; DEGRADATION; ENZYMES; PHOSPHATE COATINGS; PORE SIZE; RAT CONTROL; TISSUE;

SCAFFOLDS (BIOLOGY);

CALCIUM PHOSPHATE; CHITOSAN; LYSOZYME; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CHANNEL GATING; CONTROLLED STUDY; DEGRADATION; HISTOLOGY; IMPLANTATION; MALE; MATERIAL COATING; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; POROSITY; RAT; WEIGHT REDUCTION;

ANIMALS; CALCIUM PHOSPHATES; CHITOSAN; COATED MATERIALS, BIOCOMPATIBLE; HUMANS; IMPLANTS, EXPERIMENTAL; MALE; MATERIALS TESTING; MURAMIDASE; POROSITY; RATS; RATS, WISTAR; SURFACE PROPERTIES; TISSUE ENGINEERING; TISSUE SCAFFOLDS; X-RAY MICROTOMOGRAPHY;

EID: 84856214868     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33261     Document Type: Article

References (46)

1. Martins AM, Santos MI, Azevedo HS, Malafaya PB, Reis RL,. Natural origin scaffolds with in situ pore forming capability for bone tissue engineering applications. Acta Biomater 2008; 4: 1637-1645.
2. Martins AM, Pereira RC, Leonor IB, Azevedo HS, Reis RL,. Chitosan scaffolds incorporating lysozyme into CaP coatings produced by a biomimetic route: A novel concept for tissue engineering combining a self-regulated degradation system with in situ pore formation. Acta Biomater 2009; 5: 3328-3336.
3. Martins AM, Pham QP, Malafaya PB, Raphael RM, Kasper FK, Reis RL, Mikos AG,. Natural stimulus responsive scaffolds/cells for bone tissue engineering: Influence of lysozyme upon scaffold degradation and osteogenic differentiation of cultured marrow stromal cells induced by CaP coatings. Tissue Eng Part A 2009; 15: 1953-1963.
4. Martins AM, Salgado AJ, Azevedo HS, Leonor IB, Reis RL,. Lysozyme incorporation in biomimetic coated chitosan scaffolds: Development and behaviour in contact with osteoblastic-like cells. Tissue Eng 2006; 12: 1018-1019.
5. Reis RL, Cunha AM, Fernandes MH, Correia RN,. Treatments to induce the nucleation and growth of apatite-like layers on polymeric surfaces and foams. J Mater Sci Mater Med 1997; 8: 897-905. (Pubitemid 28005935)
6. Oliveira AL, Elvira C, Reis RL, Vazquez B, San Roman J,. Surface modification tailors the characteristics of biomimetic coatings nucleated on starch-based polymers. J Mater Sci Mater Med 1999; 10: 827-835. (Pubitemid 30064209)
7. Oliveira AL, Malafaya PB, Reis RL,. Sodium silicate gel as a precursor for the in vitro nucleation and growth of a bone-like apatite coating in compact and porous polymeric structures. Biomaterials 2003; 24: 2575-2584. (Pubitemid 36506480)
8. Habibovic P, de Groot K,. Osteoinductive biomaterials-Properties and relevance in bone repair. J Tissue Eng Regen Med 2007; 1: 25-32.
9. Liu Y, Hunziker EB, Layrolle P, De Bruijn JD, De Groot K,. Bone morphogenetic protein 2 incorporated into biomimetic coatings retains its biological activity. Tissue Eng 2004; 10: 101-108. (Pubitemid 38199365)
10. Azevedo HS, Leonor IB, Alves CM, Reis RL,. Incorporation of proteins and enzymes at different stages of the preparation of calcium phosphate coatings on a degradable substrate by a biomimetic methodology. Mater Sci Eng C: Biomimetic Supramol Sys 2005; 25: 169-179. (Pubitemid 40584239)
11. Oliveira JM, Rodrigues MT, Silva SS, Malafaya PB, Gomes ME, Viegas CA, Dias IR, Azevedo JT, Mano JF, Reis RL,. Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells. Biomaterials. 2006; 27: 6123-6137. (Pubitemid 44429972)
12. Malafaya PB, Santos TC, van Griensven M, Reis RL,. Morphology, mechanical characterization and in vivo neo-vascularization of chitosan particle aggregated scaffolds architectures. Biomaterials 2008; 29: 3914-3926.
13. Costa-Pinto AR, Salgado AJ, Correlo VM, Sol P, Bhattacharya M, Charbord P, Reis RL, Neves NM,. Adhesion, proliferation, and osteogenic differentiation of a mouse mesenchymal stem cell line (BMC9) seeded on novel melt-based chitosan/polyester 3D porous scaffolds. Tissue Eng Part A 2008; 14: 1049-1057. (Pubitemid 351862218)
14. Mendes SC, Reis RL, Bovell YP, Cunha AM, van Blitterswijk CA, de Bruijn JD,. Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: A preliminary study. Biomaterials 2001; 22: 2057-2064. (Pubitemid 32567645)
15. Marques AP, Reis RL, Hunt JA,. The biocompatibility of novel starch-based polymers and composites: In vitro studies. Biomaterials 2002; 23: 1471-1478. (Pubitemid 34037084)
16. Salgado AJ, Coutinho OP, Reis RL, Davies JE,. In vivo response to starch-based scaffolds designed for bone tissue engineering applications. J Biomed Mater Res A 2007; 80: 983-989.
17. Azevedo HS, Gama FM, Reis RL,. In vitro assessment of the enzymatic degradation of several starch based biomaterials. Biomacromolecules 2003; 4: 1703-1712. (Pubitemid 37460961)
18. Gomes ME, Azevedo HS, Moreira AR, Ella V, Kellomaki M, Reis RL,. Starch-poly(epsilon-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: Structure, mechanical properties and degradation behaviour. J Tissue Eng Regen Med 2008; 2: 243-252.
19. Tuzlakoglu K, Alves CM, Mano JF, Reis RL,. Production and characterization of chitosan fibers and 3D fiber mesh scaffolds for tissue engineering applications. Macromol Biosci 2004; 4: 811-819. (Pubitemid 39257145)
20. Pham QP, Kasper FK, Mistry AS, Sharma U, Yasko AW, Jansen JA, Mikos AG,. Analysis of the osteoinductive capacity and angiogenicity of an in vitro generated extracellular matrix. J Biomed Mater Res A 2009; 88: 295-303.
21. Young S, Patel ZS, Kretlow JD, Murphy MB, Mountziaris PM, Baggett LS, Ueda H, Tabata Y, Jansen JA, Wong M, Mikos AG,. Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng Part A 2009; 15: 2347-2362.
22. Yoshikawa T, Ohgushi H, Akahane M, Tamai S, Ichijima K,. Analysis of gene expression in osteogenic cultured marrow/hydroxyapatite construct implanted at ectopic sites: A comparison with the osteogenic ability of cancellous bone. J Biomed Mater Res. 1998; 41: 568-573. (Pubitemid 28355441)
23. Nishikawa M, Myoui A, Ohgushi H, Ikeuchi M, Tamai N, Yoshikawa H,. Bone tissue engineering using novel interconnected porous hydroxyapatite ceramics combined with marrow mesenchymal cells: Quantitative and three-dimensional image analysis. Cell Transplant 2004; 13: 367-376. (Pubitemid 39163081)
24. Uemura T, Dong J, Wang Y, Kojima H, Saito T, Iejima D, Kikuchi M, Tanaka J, Tateishi T,. Transplantation of cultured bone cells using combinations of scaffolds and culture techniques. Biomaterials 2003; 24: 2277-2286. (Pubitemid 36434046)
25. Oliveira JM, Kotokuki N, Tadokoro M, Hirose M, Mano JF, Reis RL, Ohgushi H,. Ex vivo culturing of rat bone marrow stromal cells with dexamethasone-loaded carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles enhances ectopic bone formation on tissue engineered constructs. Bone 2010; 46: 1424-1435.
26. Datta N, Holtorf HL, Sikavitsas VI, Jansen JA, Mikos AG,. Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials. 2005; 26: 971-977. (Pubitemid 39208984)
27. De Jong WH, Eelco Bergsma J, Robinson JE, Bos RR,. Tissue response to partially in vitro predegraded poly- L -lactide implants. Biomaterials 2005; 26: 1781-1791. (Pubitemid 39575321)
28. Hankiewicz J, Swierczek E,. Lysozyme in human body fluids. Clin Chim Acta 1974; 57: 205-209.
29. Porstmann B, Jung K, Schmechta H, Evers U, Pergande M, Porstmann T, Kramm HJ, Krause H,. Measurement of lysozyme in human body fluids: Comparison of various enzyme immunoassay techniques and their diagnostic application. Clin Biochem 1989; 22: 349-355. (Pubitemid 19256223)
30. Tomihata K, Ikada Y,. In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. Biomaterials 1997; 18: 567-575. (Pubitemid 27156271)
31. Lim SM, Song DK, Oh SH, Lee-Yoon DS, Bae EH, Lee JH,. In vitro and in vivo degradation behavior of acetylated chitosan porous beads. J Biomater Sci Polym Ed 2008; 19: 453-466. (Pubitemid 351311664)
32. Junge W, Troge B, Klein G, Poppe W, Gerber M,. Evaluation of a new assay for pancreatic amylase: Performance characteristics and estimation of reference intervals. Clin Biochem 1989; 22: 109-114. (Pubitemid 19121440)
33. Williams DF,. On the mechanisms of biocompatibility. Biomaterials 2008; 29: 2941-2953.
34. Babensee JE, Anderson JM, McIntire LV, Mikos AG, Host response to tissue engineered devices. Adv Drug Delivery Rev 1998; 33: 111-139. (Pubitemid 28403539)
35. Anderson JM,. Biological responses to materials. Ann Rev Mater Res 2001; 31: 81-110. (Pubitemid 33073846)
36. Luttikhuizen DT, van Amerongen MJ, de Feijter PC, Petersen AH, Harmsen MC, van Luyn MJA,. The correlation between difference in foreign body reaction between implant locations and cytokine and MMP expression. Biomaterials 2006; 27: 5763-5770. (Pubitemid 44308346)
37. denDunnen WFA, Robinson PH, vanWessel R, Pennings AJ, vanLeeuwen MBM, Schakenraad JM,. Long-term evaluation of degradation and foreign-body reaction of subcutaneously implanted poly(DL -lactide-epsilon-caprolactone). J Biomed Mater Res 1997; 36: 337-346. (Pubitemid 27335204)
38. Abe Y, Kokubo T, Yamamuro T,. Apatite coating on ceramics: Metals and polymers utilizing a biological process. J Mater Sci: Mater Med 1990; 1: 233-238. (Pubitemid 21650010)
39. Barrere F, van der Valk CM, Dalmeijer RA, van Blitterswijk CA, de Groot K, Layrolle P,. In vitro and in vivo degradation of biomimetic octacalcium phosphate and carbonate apatite coatings on titanium implants. J Biomed Mater Res A 2003; 64: 378-387. (Pubitemid 37521459)
40. Heughebaert M, LeGeros RZ, Gineste M, Guilhem A, Bonel G,. Physicochemical characterization of deposits associated with HA ceramics implanted in nonosseous sites. J Biomed Mater Res Appl Biomater 1988; 22: 257-268. (Pubitemid 19003136)
41. Radin SR, Ducheyne P,. The effect of calcium phosphate ceramic composition and structure on in vitro behavior. II. Precipitation. J Biomed Mater Res 1993; 27: 35-45. (Pubitemid 23002765)
42. den Hollander W, Patka P, Klein CP, Heidendal GA,. Macroporous calcium phosphate ceramics for bone substitution: A tracer study on biodegradation with 45Ca tracer. Biomaterials 1991; 12: 569-573.
43. Barrere F, van Blitterswijk CA, de Groot K,. Bone regeneration: Molecular and cellular interactions with calcium phosphate ceramics. Int J Nanomedicine 2006; 1: 317-332.
44. Leeuwenburgh SC, Wolke JG, Siebers MC, Schoonman J, Jansen JA,. In vitro and in vivo reactivity of porous, electrosprayed calcium phosphate coatings. Biomaterials 2006; 27: 3368-3378.
45. Dhert WJ, Klein CP, Jansen JA, van der Velde EA, Vriesde RC, Rozing PM, de Groot K,. A histological and histomorphometrical investigation of fluorapatite, magnesiumwhitlockite, and hydroxylapatite plasma-sprayed coatings in goats. J Biomed Mater Res 1993; 27: 127-138. (Pubitemid 23002775)
46. Klein CP, Wolke JG, de Blieck-Hogervorst JM, de Groot K,. Calcium phosphate plasma-sprayed coatings and their stability: An in vivo study. J Biomed Mater Res 1994; 28: 909-917. (Pubitemid 24237854)