Hypothermia, immune suppression and SDD: Can we have our cake and eat it?

Critical Care

Volumn 15, Issue 2, 2011, Pages

  Polderman, Kees H ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CYTOKINE; LEUKOTRIENE; NITRIC OXIDE;

ACCIDENTAL HYPOTHERMIA; ANTIBIOTIC THERAPY; ASEPSIS; BRAIN ISCHEMIA; CYTOKINE RELEASE; HUMAN; IMMUNE RESPONSE; INDUCED HYPOTHERMIA; INFECTION; INFECTION RISK; INJURY SEVERITY; INTENSIVE CARE UNIT; INTRACRANIAL PRESSURE; LEUKOCYTE COUNT; LIPID PEROXIDATION; MACROPHAGE; NEUTROPHIL; NONHUMAN; NOTE; PRIORITY JOURNAL; RISK REDUCTION; STANDARD DECONTAMINATION OF THE DIGESTIVE TRACT; TISSUE REPAIR; TRAUMATIC BRAIN INJURY; VENTILATOR ASSOCIATED PNEUMONIA; BRAIN INJURY; DIGESTIVE SYSTEM; FEMALE; MALE; METHODOLOGY; MICROBIOLOGY; WASTE MANAGEMENT;

BRAIN INJURIES; DECONTAMINATION; DIGESTIVE SYSTEM; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; INFECTION; MALE;

EID: 84856206648     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc10080     Document Type: Note

References (17)

1. Kamps M, Bisschops L, van der Hoeven JG, Hoedemaekers CWE. Hypothermia does not increase the risk of infection: a case control study. Crit Care 2011, 15:R48. 10.1186/cc10012, 21291523.
2. Polderman KH. Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med 2009, 37:S186-S202. 10.1097/CCM.0b013e3181aa5241, 19535947.
3. Polderman KH, Herold I. Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods. Crit Care Med 2009, 37:1101-1120. 10.1097/CCM.0b013e3181962ad5, 19237924.
4. Polderman KH. Induced hypothermia and fever control for prevention and treatment of neurological injuries. Lancet 2008, 371:1955-1969. 10.1016/S0140-6736(08)60837-5, 18539227.
5. Aibiki M, Maekawa S, Ogura S, Kinoshita Y, Kawai N, Yokono S. Effect of moderate hypothermia on systemic and internal jugular plasma IL-6 levels after traumatic brain injury in humans. J Neurotrauma 1999, 16:225-232. 10.1089/neu.1999.16.225, 10195470.
6. Kimura A, Sakurada S, Ohkuni H, Todome Y, Kurata K. Moderate hypothermia delays proinflammatory cytokine production of human peripheral blood mononuclear cells. Crit Care Med 2002, 30:1499-1502. 10.1097/00003246-200207000-00017, 12130969.
7. Suehiro E, Fujisawa H, Akimura T, Ishihara H, Kajiwara K, Kato S, Fujii M, Yamashita S, Maekawa T, Suzuki M. Increased matrix metalloproteinase-9 in blood in association with activation of interleukin-6 after traumatic brain injury: influence of hypothermic therapy. J Neurotrauma 2004, 21:1706-1711. 10.1089/neu.2004.21.1706, 15684762.
8. Dietrich WD, Chatzipanteli K, Vitarbo E, Wada K, Kinoshita K. The role of inflammatory processes in the pathophysiology and treatment of brain and spinal cord trauma. Acta Neurochir Suppl 2004, 89:69-74.
9. Schmidt OI, Heyde CE, Ertel W, Stahel PF. Closed head injury - an inflammatory disease?. Brain Res Brain Res Rev 2005, 48:388-399. 10.1016/j.brainresrev.2004.12.028, 15850678.
10. Asensio VC, Campbell IL. Chemokines in the CNS: plurifunctional mediators in diverse states. Trends Neurosci 1999, 22:504-512. 10.1016/S0166-2236(99)01453-8, 10529818.
11. Merrill JE, Benveniste EN. Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 1996, 19:331-338. 10.1016/0166-2236(96)10047-3, 8843602.
12. Morganti-Kossmann MC, Rancan M, Stahel PF, Kossmann T. Inflamatory response in acute traumatic brain injury: a double-edged sword. Curr Opin Crit Care 2002, 8:101-105. 10.1097/00075198-200204000-00002, 12386508.
13. Hemmen TM, Raman R, Guluma KZ, Meyer BC, Gomes JA, Cruz-Flores S, Wijman CA, Rapp KS, Grotta JC, Lyden PD, . ICTuS-L Investigators Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results. Stroke 2010, 41:2265-2270. 10.1161/STROKEAHA.110.592295, 20724711, ICTuS-L Investigators.
14. Kurz A, Sessler DI, Lenhardt R, . Study of Wound Infection and Temperature Group Perioperative normothermia to reduce the incidence of surgicalwound infection and shorten hospitalization. N Engl J Med 1996, 334:1209-1215. 10.1056/NEJM199605093341901, 8606715, Study of Wound Infection and Temperature Group.
15. Polderman KH, Tjong Tjin Joe R, Peerdeman SM, Vandertop WP, Girbes AR. Effects of therapeutic hypothermia on intracranial pressure and outcome in patients with severe head injury. Intensive Care Med 2002, 28:1563-1573. 10.1007/s00134-002-1511-3, 12415442.
16. Polderman KH, Peerdeman SM, Girbes AR. Hypophosphatemia and hypomagnesemia induced by cooling in patients with severe head injury. J Neurosurg 2001, 94:697-705. 10.3171/jns.2001.94.5.0697, 11354399.
17. de Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS, van der Hoeven JG, Pickkers P, Bogaers-Hofman D, van der Meer NJ, Bernards AT, Kuijper EJ, Joore JC, Leverstein-van Hall MA, Bindels AJ, Jansz AR, Wesselink RM, de Jongh BM, Dennesen PJ, van Asselt GJ, te Velde LF, Frenay IH, Kaasjager K, Bosch FH, van Iterson M, Thijsen SF, Kluge GH, Pauw W, de Vries JW, Kaan JA, et al. Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 2009, 360:20-31. 10.1056/NEJMoa0800394, 19118302.