Hypothermia does not increase the risk of infection: A case control study

Critical Care

Volumn 15, Issue 1, 2011, Pages

  Kamps, Marlijn ^a   Bisschops, Laurens A ^a   van der Hoeven, Johannes G ^a   Hoedemaekers, Cornelia W E ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ADULT; ARTICLE; BACTEREMIA; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BODY TEMPERATURE; BRAIN INJURY; CANDIDA; CASE CONTROL STUDY; CONTROLLED STUDY; FEMALE; GRAM NEGATIVE BACTERIUM; HUMAN; HYPOTHERMIA; INFECTION RISK; INJURY SEVERITY; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MENINGITIS; PNEUMONIA; PRIORITY JOURNAL; PROPENSITY SCORE; RETROSPECTIVE STUDY; STAPHYLOCOCCUS AUREUS; URINARY TRACT INFECTION; WOUND INFECTION; DIGESTIVE SYSTEM; HOSPITALIZATION; INDUCED HYPOTHERMIA; INFECTION; METHODOLOGY; MICROBIOLOGY; MIDDLE AGED; RISK ASSESSMENT; TIME; TREATMENT OUTCOME; WASTE MANAGEMENT;

ADULT; BRAIN INJURIES; CASE-CONTROL STUDIES; DECONTAMINATION; DIGESTIVE SYSTEM; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; INFECTION; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 79551541646     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc10012     Document Type: Article

References (27)

1. Jiang JY, Xu W, Li WP, Gao GY, Bao YH, Liang YM, Luo QZ. Effect of long-term mild hypothermia or short-term mild hypothermia on outcome of patients with severe traumatic brain injury. J Cereb Blood Flow Metab 2006, 26:771-776. 10.1038/sj.jcbfm.9600253, 16306933.
2. Jiang J, Yu M, Zhu C. Effect of long-term mild hypothermia therapy in patients with severe traumatic brain injury: 1-year follow-up review of 87 cases. J Neurosurg 2000, 93:546-549. 10.3171/jns.2000.93.4.0546, 11014530.
3. McIntyre LA, Fergusson DA, Hebert PC, Moher D, Hutchison JS. Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review. JAMA 2003, 289:2992-2999. 10.1001/jama.289.22.2992, 12799408.
4. Peterson K, Carson S, Carney N. Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis. J Neurotrauma 2008, 25:62-71. 10.1089/neu.2007.0424, 18355159.
5. Ishikawa K, Tanaka H, Shiozaki T, Takaoka M, Ogura H, Kishi M, Shimazu T, Sugimoto H. Characteristics of infection and leukocyte count in severely head-injured patients treated with mild hypothermia. J Trauma 2000, 49:912-922. 10.1097/00005373-200011000-00020, 11086785.
6. Fagerli J, Chendrasekhar A. The effect of severe closed head injury on the incidence of nosocomial infections. W V Med J 1996, 92:265-267.
7. Rondina C, Videtta W, Petroni G, Lujan S, Schoon P, Mori LB, Matkovich J, Carney N, Chesnut R. Mortality and morbidity from moderate to severe traumatic brain injury in Argentina. J Head Trauma Rehabil 2005, 20:368-376. 10.1097/00001199-200507000-00008, 16030443.
8. Oconnor E, Venkatesh B, Mashongonyika C, Lipman J, Hall J, Thomas P. Serum procalcitonin and C-reactive protein as markers of sepsis and outcome in patients with neurotrauma and subarachnoid haemorrhage. Anaesth Intensive Care 2004, 32:465-470.
9. Kox M, Pompe JC, Pickkers P, Hoedemaekers CW, van Vugt AB, van der Hoeven JG. Increased vagal tone accounts for the observed immune paralysis in patients with traumatic brain injury. Neurology 2008, 70:480-485. 10.1212/01.wnl.0000279479.69502.3e, 18250293.
10. Biggar WD, Bohn D, Kent G. Neutrophil circulation and release from bone marrow during hypothermia. Infect Immun 1983, 40:708-712. 264913, 6840858.
11. Biggar WD, Barker C, Bohn D, Kent G. Partial recovery of neutrophil functions during prolonged hypothermia in pigs. J Appl Physiol 1986, 60:1186-1189.
12. Diestel A, Roessler J, Berger F, Schmitt KR. Hypothermia downregulates inflammation but enhances IL-6 secretion by stimulated endothelial cells. Cryobiology 2008, 57:216-222. 10.1016/j.cryobiol.2008.08.005, 18790695.
13. Hashiguchi N, Shiozaki T, Ogura H, Tanaka H, Koh T, Noborio M, Fugita K, Akimau P, Kuwagata Y, Shimazu T, Sugimoto H. Mild hypothermia reduces expression of heat shock protein 60 in leukocytes from severely head-injured patients. J Trauma 2003, 55:1054-1060. 10.1097/01.TA.0000033252.43742.8B, 14676650.
14. Bergmans DC, Bonten MJ, Gaillard CA, Paling JC, van der Geest S, van Tiel FH, Beysens AJ, de Leeuw PW, Stobberingh EE. Prevention of ventilator-associated pneumonia by oral decontamination: a prospective, randomized, double-blind, placebo-controlled study. Am J Respir Crit Care Med 2001, 164:382-388.
15. Chan EY, Ruest A, Meade MO, Cook DJ. Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ 2007, 334:889. 10.1136/bmj.39136.528160.BE, 1857782, 17387118.
16. Pugin J, Auckenthaler R, Lew DP, Suter PM. Oropharyngeal decontamination decreases incidence of ventilator-associated pneumonia. A randomized, placebo-controlled, double-blind clinical trial. JAMA 1991, 265:2704-2710. 10.1001/jama.265.20.2704, 2023353.
17. de Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS, van der Hoeven JG, Pickkers P, Bogaers-Hofman D, van der Meer NJ, Bernards AT, Kuijper EJ, Joore JC, Leverstein-van Hall MA, Bindels AJ, Jansz AR, Wesselink RM, de Jongh BM, Dennesen PJ, van Asselt GJ, te Velde LF, Frenay IH, Kaasjager K, Bosch FH, van Iterson M, Thijsen SF, Kluge GH, Pauw W, de Vries JW, Kaan JA, et al. Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 2009, 360:20-31. 10.1056/NEJMoa0800394, 19118302.
18. Polderman KH. Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med 2009, 37:S186-S202. 10.1097/CCM.0b013e3181aa5241, 19535947.
19. Shiozaki T, Hayakata T, Taneda M, Nakajima Y, Hashiguchi N, Fujimi S, Nakamori Y, Tanaka H, Shimazu T, Sugimoto H. A multicenter prospective randomized controlled trial of the efficacy of mild hypothermia for severely head injured patients with low intracranial pressure. Mild Hypothermia Study Group in Japan. J Neurosurg 2001, 94:50-54. 10.3171/jns.2001.94.1.0050, 11147897.
20. Ewig S, Torres A, El-Ebiary M, Fábregas N, Hernández C, González J, Nicolás JM, Soto L. Bacterial colonization patterns in mechanically ventilated patients with traumatic and medical head injury. Incidence, risk factors, and association with ventilator-associated pneumonia. Am J Respir Crit Care Med 1999, 159:188-198.
21. Stoutenbeek CP, van Saene HK, Miranda DR, Zandstra DF. The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients. Intensive Care Med 1984, 10:185-192. 10.1007/BF00259435, 6470306.
22. Bergmans DC, Bonten MJ, Gaillard CA, Paling JC, van der Geest S, van Tiel FH, Beysens AJ, de Leeuw PW, Stobberingh EE. Prevention of ventilator-associated pneumonia by oral decontamination: a prospective, randomized, double-blind, placebo-controlled study. Am J Respir Crit Care Med 2001, 164:382-388.
23. Schuetz P, Affolter B, Hunziker S, Winterhalder C, Fischer M, Balestra GM, Hunziker P, Marsch S. Serum procalcitonin, C-reactive protein and white blood cell levels following hypothermia after cardiac arrest: a retrospective cohort study. Eur J Clin Invest 2010, 40:376-381. 10.1111/j.1365-2362.2010.02259.x, 20192974.
24. Verwaest C, Verhaegen J, Ferdinande P, Schetz M, Van den Berghe G, Verbist L, Lauwers P. Randomized, controlled trial of selective digestive decontamination in 600 mechanically ventilated patients in a multidisciplinary intensive care unit. Crit Care Med 1997, 25:63-71. 10.1097/00003246-199701000-00014, 8989178.
25. Lingnau W, Berger J, Javorsky F, Fille M, Allerberger F, Benzer H. Changing bacterial ecology during a five-year period of selective intestinal decontamination. J Hosp Infect 1998, 39:195-206. 10.1016/S0195-6701(98)90258-4, 9699139.
26. Hammond JM, Potgieter PD, Saunders GL, Forder AA. Double-blind study of selective decontamination of the digestive tract in intensive care. Lancet 1992, 340:5-9. 10.1016/0140-6736(92)92422-C, 1351620.
27. de Jonge E, Schultz MJ, Spanjaard L, Bossuyt PM, Vroom MB, Dankert J, Kesecioglu J. Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial. Lancet 2003, 362:1011-1016. 10.1016/S0140-6736(03)14409-1, 14522530.